chlorambucil has been researched along with Cancer of Gastrointestinal Tract in 6 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with intestinal small cell lymphosarcoma can present identical clinical signs, and differentiating between these two conditions can be a challenge." | 1.39 | Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis. ( Al-Ghazlat, S; de Rezende, CE, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Rezende, CE | 1 |
| Al-Ghazlat, S | 1 |
| Móller, TR | 1 |
| Brandt, L | 1 |
| Kónyves, I | 1 |
| Lindberg, G | 1 |
| Bennett, JM | 1 |
| Moloney, WC | 1 |
| Greene, MH | 1 |
| Boice, JD | 1 |
| Berk, PD | 1 |
| Goldberg, JD | 1 |
| Donovan, PB | 1 |
| Fruchtman, SM | 1 |
| Berlin, NI | 1 |
| Wasserman, LR | 1 |
| Berenbaum, MC | 1 |
| Sheard, CE | 1 |
| Reittie, JR | 1 |
| Bundick, RV | 1 |
| Halkin, H | 1 |
| Meytes, D | 1 |
| Militeanu, J | 1 |
| Ramot, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Phase 2 Study of Efficacy and Safety of Pegylated Interferon-alfa 2a in Polycythemia Vera Patients[NCT00241241] | Phase 2 | 40 participants | Interventional | 2004-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for chlorambucil and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols.
Topics: Acute Disease; Age Factors; Bloodletting; Chlorambucil; Combined Modality Therapy; False Positive Re | 1986 |
5 other studies available for chlorambucil and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cat Diseases; Cats; Chlorambucil; Diet; Gastr | 2013 |
Therapeutic effect of Leo 1031, an alkylating corticosteroid ester; in lymphoproliferative disorders. II. Lymphocytic lymphoma.
Topics: Adult; Aged; Bone Marrow; Chlorambucil; Drug Evaluation; Drug Therapy, Combination; Esters; Female; | 1975 |
Acute myeloid leukemia and other myelopathic disorders following treatment with alkylating agents.
Topics: Adolescent; Adult; Aged; Alkylating Agents; Anemia, Aplastic; Child; Child, Preschool; Chlorambucil; | 1987 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; | 1974 |
Multiple lymphomatous polyposis of the gastrointestinal tract.
Topics: Autopsy; Biopsy; Celiac Disease; Chlorambucil; Gastrointestinal Neoplasms; Humans; Intestinal Polyps | 1973 |