chlorambucil has been researched along with Cancer, Embryonal in 33 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with germ cell tumors may be divided into "good risk" (high likelihood of complete response) and "poor risk" (low likelihood of complete response) based on pretreatment serum tumor markers, extent of disease, histology, and primary site." | 2.37 | Chemotherapy for germ cell tumors. ( Bosl, GJ; Motzer, RJ, 1987) |
| "Incidence of testicular cancer is low in Japan." | 1.33 | Treatment outcome of metastatic testicular cancer at a single institution in Japan, a country with low incidence of germ cell tumor. ( Akaza, H; Hasegawa, Y; Hattori, K; Hinotsu, S; Kawai, K; Kojima, H; Miyanaga, N; Oikawa, T; Sekido, N; Shimazui, T, 2006) |
| "Testicular tumor is a rare diseases in Japan." | 1.27 | [Clinical management of testicular tumors]. ( Kotake, T; Miki, T, 1984) |
| "Disseminated germ cell testicular cancer proved to be highly sensitive to platinum-containing chemotherapy regimens." | 1.27 | Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum for advanced germ cell testis tumors: Brazilian experience. ( de Góes, GM; Simon, SD; Srougi, M, 1985) |
| "Bilateral primary germ cell tumors are uncommon but not rare in men with primary testicular tumors." | 1.26 | Problems in management of primary bilateral germ cell testicular tumors: report of 3 cases and review of literature. ( Constable, WC; Morris, SA; Vaughan, ED, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (90.91) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 1 (3.03) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MIALE, A | 1 |
| KESLER, K | 1 |
| Kawai, K | 1 |
| Hinotsu, S | 1 |
| Oikawa, T | 1 |
| Sekido, N | 1 |
| Hattori, K | 1 |
| Miyanaga, N | 1 |
| Hasegawa, Y | 1 |
| Kojima, H | 1 |
| Shimazui, T | 1 |
| Akaza, H | 1 |
| Base, J | 1 |
| Navrátil, P | 1 |
| Vugrin, D | 5 |
| Martini, N | 3 |
| Whitmore, WF | 7 |
| Golbey, RB | 6 |
| Herr, HW | 1 |
| Sogani, P | 3 |
| Kotake, T | 1 |
| Miki, T | 1 |
| Morris, SA | 1 |
| Vaughan, ED | 1 |
| Constable, WC | 1 |
| Valdez, VA | 1 |
| Planas, AT | 1 |
| Lopez, VF | 1 |
| Goldberg, M | 1 |
| Herrera, NE | 1 |
| Abdyldaev, TA | 1 |
| Tiuliandin, SA | 3 |
| Batov, SV | 1 |
| Srougi, M | 1 |
| Simon, SD | 1 |
| de Góes, GM | 1 |
| Fraley, EE | 1 |
| Narayan, P | 1 |
| Vogelzang, NJ | 2 |
| Kennedy, BJ | 1 |
| Lange, PH | 1 |
| Israel, A | 1 |
| Bosl, GJ | 6 |
| Whitmore, W | 1 |
| Germa Lluch, JR | 1 |
| Brenner, J | 1 |
| Bassoulet, J | 1 |
| Raoul, Y | 1 |
| Garetta, L | 1 |
| Gluckman, R | 1 |
| Geller, NL | 2 |
| Herr, H | 2 |
| Morse, M | 2 |
| Bains, M | 1 |
| Carey, R | 1 |
| Auman, J | 1 |
| Chan, E | 1 |
| Hida, S | 1 |
| Kawakita, M | 1 |
| Takenawa, J | 1 |
| Fukuzawa, S | 1 |
| Okuno, H | 1 |
| Yamauchi, T | 1 |
| Oishi, K | 1 |
| Nishio, Y | 1 |
| Takeuchi, H | 1 |
| Okada, K | 1 |
| Motzer, RJ | 1 |
| Leitner, SP | 1 |
| Atlas, SA | 1 |
| Sealey, JE | 1 |
| Preibisz, JJ | 1 |
| Scheiner, E | 1 |
| Bajorunas, D | 1 |
| Carter, GE | 1 |
| Lieskovsky, G | 1 |
| Skinner, DG | 1 |
| Daniels, JR | 1 |
| Sakalo, VS | 1 |
| Klimenko, IA | 1 |
| Iaremko, VN | 1 |
| Zaparin, VK | 1 |
| Weissbach, L | 2 |
| Lange, CE | 1 |
| Meyhöfer, W | 1 |
| Ryssel, HJ | 1 |
| Sonntag, RW | 1 |
| Brunner, KW | 1 |
| Dargent, M | 1 |
| Pommatau, E | 1 |
| Brunat, M | 1 |
| Gudgeon, DH | 1 |
| Vahlensieck, W | 2 |
2 reviews available for chlorambucil and Cancer, Embryonal
| Article | Year |
|---|---|
Chemotherapy for germ cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1987 |
[Chemotherapy of disseminated germ cell tumors of the testis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1987 |
1 trial available for chlorambucil and Cancer, Embryonal
| Article | Year |
|---|---|
VAB-6: an effective chemotherapy regimen for patients with germ-cell tumors.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleo | 1986 |
30 other studies available for chlorambucil and Cancer, Embryonal
| Article | Year |
|---|---|
OVARIAN DISGERMINOMA. REPORT OF A CASE TREATED WITH ACTINOMYCIN D, CHLORAMBUCIL, AND METHOTREXATE AFTER MASSIVE IRRADIATION.
Topics: Chlorambucil; Dactinomycin; Drug Therapy; Dysgerminoma; Female; Humans; Methotrexate; Neoplasms; Neo | 1964 |
Treatment outcome of metastatic testicular cancer at a single institution in Japan, a country with low incidence of germ cell tumor.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Ci | 2006 |
Modern trends in the management of non-seminomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined | 1984 |
VAB-3 combination chemotherapy in primary mediastinal germ cell tumors.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisp | 1982 |
VAB-6 combination chemotherapy in resected stage II-B testis cancer.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; | 1983 |
VAB-5 combination chemotherapy in prognostically poor risk patients with germ cell tumors.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisp | 1983 |
Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum combination chemotherapy in metastatic testis cancer--a 1-year program.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; | 1982 |
[Clinical management of testicular tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1984 |
Problems in management of primary bilateral germ cell testicular tumors: report of 3 cases and review of literature.
Topics: Adult; Chlorambucil; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Germ Cell and Embryonal; P | 1976 |
Adenosarcoma of uterus and ovary: a clinicopathologic study of two cases.
Topics: Adult; Chlorambucil; Cyclophosphamide; Cytoplasm; Female; Humans; Middle Aged; Neoplasm Metastasis; | 1979 |
[Results of chemotherapy in patients with disseminated testicular tumors].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1990 |
[Infusion of high doses of platidiam in the treatment of patients with germ cell testicular tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1990 |
Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum for advanced germ cell testis tumors: Brazilian experience.
Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brazil; Chlorambucil; Ci | 1985 |
Surgical treatment of patients with stages I and II nonseminomatous testicular cancer.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Castration; Chlorambuc | 1985 |
The results of chemotherapy for extragonadal germ-cell tumors in the cisplatin era: the Memorial Sloan-Kettering Cancer Center experience (1975 to 1982).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1985 |
Bleomycin in germ cell testicular tumors (GCTT).
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1985 |
Effect of treatment on fertility and sexual function in males with metastatic nonseminomatous germ cell tumors of testis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1985 |
[Advanced non-seminoma germinal tumors of the testicle. Therapeutic strategy and method of action of chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1986 |
Alternating cycles of etoposide plus cisplatin and VAB-6 in the treatment of poor-risk patients with germ cell tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1987 |
[VAB-6 combination chemotherapy in patients with stage II, III testicular tumor].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1986 |
Altered renin and aldosterone excretion in patients treated for metastatic germ cell tumours.
Topics: Aldosterone; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyc | 1987 |
Pituitary and testicular hormonal function after treatment for germ cell tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1987 |
Reassessment of the role of adjunctive surgical therapy in the treatment of advanced germ cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1987 |
[Experience in the treatment of stage III and IV testicular tumors other than seminoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Ci | 1988 |
[Testicular histology, ejaculate and nucleoprotein content of spermatozoa in patients with treated testicular tumors].
Topics: Adult; Biopsy; Chlorambucil; Dactinomycin; DNA; Dysgerminoma; Ejaculation; Fertility; Humans; Male; | 1974 |
[The treatment of choriocarcinoma and malignant testicular neoplasms].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide; | 1967 |
[Apropos of an experience with the polychemotherapy of cancer].
Topics: Adult; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Dysgermi | 1968 |
Mixed mesodermal tumour of the uterus occurring after radiotherapy.
Topics: Aged; Chlorambucil; Cystadenoma; Female; Humans; Neoplasms, Germ Cell and Embryonal; Neoplasms, Mult | 1968 |
[Extended semicastration, lymphadenectomy and extended lymphadenectomy, radiotherapy and cystostatic triple-drug interval therapy of germinal testicular neoplasms].
Topics: Antineoplastic Agents; Castration; Chlorambucil; Cobalt Isotopes; Dactinomycin; Humans; Lymph Node E | 1968 |
Operative and cytostatic treatment of germinal tumours of the testis.
Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Child, Preschool; Chlorambucil; Cyclic | 1973 |