chlorambucil has been researched along with Bright Disease in 103 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Bright Disease: A historical classification which is no longer used. It described acute glomerulonephritis, acute nephritic syndrome, or acute nephritis. Named for Richard Bright.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty adults with steroid resistant idiopathic glomerulonephritis were randomly assigned to symptomatic treatment only or to a 6-month course of methylprednisolone and prednisolone alternated with chlorambucil every other month." | 9.08 | Evaluation of efficacy of methylprednisolone, prednisolone and chlorambucil in idiopathic glomerulonephritis. ( Das, R; Jaswal, TS; Nand, N, 1997) |
| " The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy." | 7.67 | Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984) |
| "Patients with prednisone-resistant nephrotic syndrome and biopsy-proven focal segmental glomerulosclerosis were treated with intravenous methylprednisone." | 7.67 | Treatment of childhood prednisone-resistant nephrotic syndrome and focal segmental glomerulosclerosis with intravenous methylprednisolone and oral alkylating agents. ( Brock, P; Griswold, WR; Mendoza, SA; Prime, DJ; Reznik, VM; Tune, BM; Vazquez, M, 1987) |
| "Thirty adults with steroid resistant idiopathic glomerulonephritis were randomly assigned to symptomatic treatment only or to a 6-month course of methylprednisolone and prednisolone alternated with chlorambucil every other month." | 5.08 | Evaluation of efficacy of methylprednisolone, prednisolone and chlorambucil in idiopathic glomerulonephritis. ( Das, R; Jaswal, TS; Nand, N, 1997) |
| "Twenty-five adult patients with idiopathic membranous nephropathy (IMN) and nephrotic syndrome (NS) who had participated at a long-term randomized trial with steroid and chlorambucil for six months, underwent repeated renal biopsies." | 5.06 | Clinical and morphologic evolution of idiopathic membranous nephropathy. ( Cagnoli, L; Casanova, S; Donini, U; Pasquali, S; Zucchelli, P, 1986) |
| "Sixty-seven adults with idiopathic membranous nephropathy and the nephrotic syndrome were randomly assigned to symptomatic treatment only or to a six-month course of methylprednisolone alternated with chlorambucil every other month." | 5.05 | Controlled trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy. ( Cagnoli, L; Grassi, C; Imbasciati, E; Limido, D; Pasquali, S; Passerini, P; Ponticelli, C; Pozzi, C; Volpini, T; Zucchelli, P, 1984) |
| "In 110 patients with mesangioproliferative glomerulonephritis the treatment (n = 48) with chlorambucil, warfarin, dipyridamol and prednisone (CAA) and the treatment with imuran and prednisone (CP, n = 23) are compared with the conditions of an untreated control group." | 5.05 | [Glomerulonephritis therapy. Immunosuppression or coagulation inhibitors - a comparison]. ( Lakner, V; Ratner, M; Schmitt, E; Sinn, W; Tomilina, N, 1980) |
| " For instance, in patients with idiopathic membranous glomerulonephritis a six months treatment with chlorambucil (0." | 5.05 | [Drug treatment of chronic glomerulonephritis: pro]. ( Brodehl, J; Helmchen, U; Koch, KM; Kühn, K, 1985) |
| "163 patients with diffuse lupus glomerulonephritis, proven by renal biopsy, were divided into four therapeutic trial groups: 67 were put on corticosteroids alone, 11 on corticosteroids and azathioprine, 32 on corticosteroids and cyclophosphamide, and 53 on corticosteroids and chlorambucil and were followed up for several years." | 5.04 | Comparison of chlorambucil, azathioprine or cyclophosphamide combined with corticosteroids in the treatment of lupus nephritis. ( Osman, LM; Sabbour, MS, 1979) |
| "A prospective study was performed in order to evaluate the efficacy of oral cyclophosphamide and chlorambucil in inducing a remission in children with steroid-resistant primary nephrotic syndrome (NS)." | 3.68 | Long-term follow-up in children with steroid-resistant nephrotic syndrome. ( Bakkaloglu, A; Besbas, N; Saatci, O; Topaloglu, R, 1992) |
| "Children suffering from different forms of glomerulonephritis were examined for the sensitivity of peripheral blood lymphocytes to the antiproliferative action of chlorambucil in vitro." | 3.68 | [Antiprolifirative effect of chlorbutin and sensitivity of patients with glomerulonephritis to this drug]. ( Dolomanova, OE; Naumova, VI; Pukhal'skiĭ, AL; Toptygina, AP; Torubarova, NA, 1991) |
| " The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy." | 3.67 | Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984) |
| "Patients with prednisone-resistant nephrotic syndrome and biopsy-proven focal segmental glomerulosclerosis were treated with intravenous methylprednisone." | 3.67 | Treatment of childhood prednisone-resistant nephrotic syndrome and focal segmental glomerulosclerosis with intravenous methylprednisolone and oral alkylating agents. ( Brock, P; Griswold, WR; Mendoza, SA; Prime, DJ; Reznik, VM; Tune, BM; Vazquez, M, 1987) |
| "A 55-year-old man was treated during 22 months with chlorambucil (total dose : 4 218 g) for glomerulonephritis." | 3.66 | [Acute leukaemia during immunosuppressive treatment. One case (author's transl)]. ( Blanc, AP; Carcassonne, Y; Dalivoust, P; Gastaut, JA; Murisasco, A; Sébahoun, G, 1981) |
| "The classical type of Wegener's granulomatosis encompasses a necrotizing granulomatous vasculitis of the upper and lower respiratory tracts and a necrotizing glomerulonephritis." | 2.36 | [Wegener's granulomatosis and Wegener's Granuloma (author's transl)]. ( Chilla, R, 1980) |
| "Children with systemic lupus erythematosus and nephritis may benefit from the addition of cytotoxic agents to their corticosteroid regime, although the indications for this are not clear, and controlled evidence is lacking." | 2.36 | Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children. ( Cameron, JS, 1979) |
| "Juvenile idiopathic arthritis was diagnosed and kidney biopsy examination showed mesangial glomerulonephritis with immunoglobulin M deposits." | 1.39 | Nephrotic syndrome due to immunoglobulin M mesangial glomerulonephritis preceding juvenile idiopathic arthritis. ( Alvarado, C; Balestracci, A; Cuttica, RJ; Lago, N; Voyer, LE; Zardini, M, 2013) |
| "Nephrotic syndrome was observed in nine patients." | 1.28 | Glomerulonephritis in chronic lymphocytic leukemia and related B-cell lymphomas. ( Fillastre, JP; Francois, A; Mignon, F; Mougenot, B; Moulin, B; Ronco, PM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (91.26) | 18.7374 |
| 1990's | 7 (6.80) | 18.2507 |
| 2000's | 1 (0.97) | 29.6817 |
| 2010's | 1 (0.97) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Voyer, LE | 1 |
| Alvarado, C | 1 |
| Cuttica, RJ | 1 |
| Balestracci, A | 1 |
| Zardini, M | 1 |
| Lago, N | 1 |
| BARIETY, J | 9 |
| LAGRUE, G | 9 |
| SAFAR, M | 1 |
| HESSE, JC | 1 |
| MILLIEZ, P | 4 |
| Alzamora, MG | 1 |
| Schmidli, M | 1 |
| Hess, U | 1 |
| Cathomas, R | 1 |
| von Moos, R | 1 |
| Zosin, C | 2 |
| Mănescu, N | 2 |
| Schwarzkopf, A | 2 |
| Adams, DA | 1 |
| Gordon, A | 1 |
| Maxwell, MH | 1 |
| Chilla, R | 1 |
| Andreeva, NE | 1 |
| Nikolaev, AIu | 1 |
| Varshavskii, VA | 1 |
| Chernokhvostova, EV | 1 |
| Guseĭnova, LA | 1 |
| Ponticelli, C | 6 |
| Banfi, G | 1 |
| Imbasciati, E | 3 |
| Tarantino, A | 1 |
| Zucchelli, P | 6 |
| Cagnoli, L | 3 |
| Pozzi, C | 2 |
| Grassi, C | 2 |
| Limido, D | 2 |
| Pasquali, S | 3 |
| Passerini, P | 3 |
| Volpini, T | 2 |
| Locatelli, F | 1 |
| Mustonen, J | 1 |
| Pasternack, A | 1 |
| Abuelo, JG | 1 |
| Esparza, AR | 1 |
| Garella, S | 1 |
| Vasmant, D | 1 |
| Bensman, A | 1 |
| Baudon, JJ | 1 |
| Rathery, S | 1 |
| Lasfargues, G | 1 |
| Blanc, AP | 2 |
| Gastaut, JA | 2 |
| Sébahoun, G | 1 |
| Dalivoust, P | 1 |
| Murisasco, A | 1 |
| Carcassonne, Y | 2 |
| Kleinknecht, C | 2 |
| Broyer, M | 2 |
| Jarde, O | 1 |
| Guillot, M | 1 |
| McEnery, PT | 1 |
| Strife, CF | 1 |
| Donadio, JV | 2 |
| Schmähl, D | 1 |
| Habs, M | 1 |
| Lorenz, M | 1 |
| Wagner, I | 1 |
| Schmitt, E | 1 |
| Sinn, W | 3 |
| Lakner, V | 1 |
| Ratner, M | 2 |
| Tomilina, N | 2 |
| Nand, N | 1 |
| Das, R | 1 |
| Jaswal, TS | 1 |
| Dussol, B | 1 |
| Kaplanski, G | 1 |
| Daniel, L | 1 |
| Brunet, P | 1 |
| Pellissier, JF | 1 |
| Berland, Y | 1 |
| Schütterle, G | 1 |
| Goubeaud, G | 1 |
| Sabbour, MS | 1 |
| Osman, LM | 1 |
| Simon, NM | 1 |
| Rosenberg, MJ | 1 |
| Sitnitskaia, IG | 1 |
| Bagdasarova, IV | 1 |
| Panchenko, VI | 1 |
| Hagge, W | 1 |
| Cameron, JS | 4 |
| Slack, TK | 1 |
| Holley, KE | 1 |
| Ilstrup, DM | 1 |
| Ratner, MIa | 4 |
| Tomilina, NA | 3 |
| Samokhina, NM | 2 |
| Klaus, D | 1 |
| Wasik, M | 1 |
| Rancewicz, Z | 2 |
| Morzycka, M | 1 |
| Juskowa, J | 1 |
| Orłowski, T | 1 |
| Bernard, D | 1 |
| Druet, P | 2 |
| Guenel, J | 1 |
| Pollak, VE | 1 |
| Brandis, M | 2 |
| Krohn, HP | 1 |
| Hanke, K | 1 |
| Brodehl, J | 2 |
| Lenoir, G | 1 |
| Guesry, P | 1 |
| Gagnadoux, MF | 1 |
| Coggins, CH | 1 |
| Gavriushova, LP | 1 |
| Matvvev, MP | 1 |
| Kliukina, SS | 1 |
| Shevchenko, IA | 1 |
| Budakova, LV | 1 |
| Naumova, VI | 2 |
| Traver, JA | 1 |
| Guajardo, DS | 1 |
| Botella, J | 1 |
| Epstein, WV | 2 |
| Gordon, RI | 1 |
| Smirnova, MP | 1 |
| Gnateĭko, OZ | 1 |
| Krause, PH | 1 |
| Hünermund, G | 1 |
| Bahlmann, J | 1 |
| Etienne, I | 2 |
| Moulin, B | 3 |
| Godin, M | 2 |
| Czernichow, P | 2 |
| Dubois, D | 2 |
| Dhib, M | 2 |
| Fillastre, JP | 3 |
| Besbas, N | 1 |
| Topaloglu, R | 1 |
| Saatci, O | 1 |
| Bakkaloglu, A | 1 |
| Ronco, PM | 1 |
| Mougenot, B | 1 |
| Francois, A | 1 |
| Mignon, F | 1 |
| Pukhal'skiĭ, AL | 1 |
| Toptygina, AP | 1 |
| Dolomanova, OE | 1 |
| Torubarova, NA | 1 |
| Schulman, SL | 1 |
| Kaiser, BA | 1 |
| Polinsky, MS | 1 |
| Srinivasan, R | 1 |
| Baluarte, HJ | 1 |
| Mohácsi, G | 1 |
| Magori, A | 1 |
| Sonkodi, S | 1 |
| Casanova, S | 1 |
| Donini, U | 1 |
| Klinkmann, H | 1 |
| Nizze, H | 1 |
| Griswold, WR | 1 |
| Tune, BM | 1 |
| Reznik, VM | 1 |
| Vazquez, M | 1 |
| Prime, DJ | 1 |
| Brock, P | 1 |
| Mendoza, SA | 1 |
| Biriukova, LS | 2 |
| Makurov, AI | 1 |
| Andrassy, K | 1 |
| Waldherr, R | 1 |
| Ritz, E | 1 |
| Kühn, K | 1 |
| Koch, KM | 1 |
| Helmchen, U | 1 |
| Monchakovskiĭ, SF | 1 |
| Boulton-Jones, M | 1 |
| Robinson, R | 1 |
| Ogg, C | 1 |
| Mukherjee, AP | 1 |
| Kampf, D | 1 |
| Baethke, R | 1 |
| Golde, D | 1 |
| Epstein, W | 1 |
| Wojnarowski, M | 2 |
| Wyszyńska, T | 2 |
| Barnett, EV | 1 |
| Bluestone, R | 1 |
| Cracchiolo, A | 1 |
| Goldberg, LS | 1 |
| Kantor, GL | 1 |
| McIntosh, RM | 1 |
| Rafii, MR | 1 |
| Betow, C | 1 |
| Ogg, CS | 1 |
| Turner, DR | 1 |
| Weller, RO | 1 |
| Zech, P | 1 |
| Richard, P | 1 |
| Blanc-Brunat, N | 1 |
| Labeeuw, M | 1 |
| Colon, S | 1 |
| Pozet, N | 1 |
| Dupont, E | 1 |
| Fries, D | 1 |
| Traeger, J | 1 |
| Skinner, MD | 1 |
| Schwartz, RS | 1 |
| Clarkson, AR | 1 |
| Robson, JS | 1 |
| Habib, R | 1 |
| Levy, M | 1 |
| Linshaw, MA | 1 |
| Gruskin, AB | 1 |
| Joppich, R | 1 |
| Orlowski, T | 1 |
| Gradowska, L | 1 |
| Lao, M | 1 |
| Rowinska, D | 1 |
| Shekhter, SIu | 1 |
| Ar'eva, EM | 1 |
| Tsykin, DB | 1 |
| Hirbec, G | 1 |
| Johnson, JR | 2 |
| McGovern, VJ | 2 |
| May, J | 1 |
| Lauer, C | 1 |
| von Domarus, H | 1 |
| Ignatova, MS | 3 |
| Fokeeva, VV | 3 |
| Korovina, NA | 3 |
| Levitskaia, SV | 3 |
| Halpern, B | 1 |
| Morard, JC | 1 |
| Fray, A | 1 |
| Samarcq, P | 1 |
| Fritel, D | 1 |
| Lur'e, KB | 1 |
| Iakubchik, FM | 1 |
| Iacob, G | 1 |
| Sabo, I | 1 |
| Gluhovschi, G | 1 |
| Manassero, J | 1 |
| Vaillaud, JC | 1 |
| Paglia, R | 1 |
| Geneste, F | 1 |
| Lurbe, KB | 1 |
| Oechslen, D | 1 |
| Kluthe, R | 1 |
| Sarre, H | 1 |
| Rowecka-Trzebicka, K | 1 |
| Nowak, S | 1 |
| Bodalski, J | 1 |
| Margolis, A | 1 |
| Michalak, A | 1 |
| Brass, H | 1 |
| Jacquillat, C | 1 |
| Grupe, WE | 1 |
| Heymann, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study of Rituximab or Cyclophosphamide Combined With Steroids in the Treatment of Idiopathic Membranous Nephropathy[NCT05514015] | Phase 4 | 72 participants (Anticipated) | Interventional | 2022-08-25 | Not yet recruiting | ||
| Ofatumumab in Children With Steroid- and Calcineurin-inhibitor-resistant Nephrotic Syndrome: a Double-blind Randomized, Controlled, Superiority Trial[NCT02394106] | Phase 2 | 13 participants (Actual) | Interventional | 2015-07-31 | Terminated | ||
| Ofatumumab Versus Rituximab in Children With Steroid and Calcineurin Inhibitor-dependent Idiopathic Nephrotic Syndrome: an Open-label, Randomized, Controlled, Superiority Trial.[NCT02394119] | Phase 2 | 140 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for chlorambucil and Bright Disease
| Article | Year |
|---|---|
[Wegener's granulomatosis and Wegener's Granuloma (author's transl)].
Topics: Chlorambucil; Cyclophosphamide; Glomerulonephritis; Glucocorticoids; Granuloma, Lethal Midline; Gran | 1980 |
Immunosuppressive therapy in primary glomerulonephritis (pros).
Topics: Adrenocorticotropic Hormone; Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulone | 1982 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Medical treatment of glomerular diseases.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Child; Chlorambucil; Cyclophosphamid | 1978 |
[Haematuria in children. III. Treatment of glomerular diseases (author's transl)].
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Glomerulonephri | 1978 |
Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children.
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppressive A | 1979 |
Therapy of idiopathic membranous nephropathy.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Chlorambucil; Drug Evaluation; Drug Therapy, C | 1987 |
[Therapy of lupus-nephritis using corticosteroids and immunosuppressive agents].
Topics: Adrenal Cortex Hormones; Antibodies, Antinuclear; Azathioprine; Beta-Globulins; Chlorambucil; Cyclop | 1974 |
[Indications for immunosuppressive treatment in kidney diseases of children].
Topics: Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Azathioprine; Chil | 1969 |
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
The effect of drugs on immunological renal disease.
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Azathioprine; Chlorambucil; Cyclophosphamide; Glomeru | 1972 |
Management of the nephrotic syndrome.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos | 1974 |
[Nephrotic syndrome in childhood].
Topics: Adolescent; Age Factors; Azathioprine; Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphami | 1974 |
Immunosuppressant agents in the treatment of glomerulonephritis. 2. Cytotoxic drugs.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antilymphocyte Serum; Antineoplastic Agents; Azath | 1971 |
15 trials available for chlorambucil and Bright Disease
| Article | Year |
|---|---|
Controlled trial of monthly alternated courses of steroid and chlorambucil for idiopathic membranous nephropathy.
Topics: Chlorambucil; Clinical Trials as Topic; Creatinine; Drug Administration Schedule; Drug Therapy, Comb | 1983 |
Controlled trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Creatinine; Drug Administration Schedule; Femal | 1984 |
[Glomerulonephritis therapy. Immunosuppression or coagulation inhibitors - a comparison].
Topics: Anticoagulants; Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Drug Therapy, Combinatio | 1980 |
Evaluation of efficacy of methylprednisolone, prednisolone and chlorambucil in idiopathic glomerulonephritis.
Topics: Adult; Anti-Inflammatory Agents; Chlorambucil; Drug Therapy, Combination; Female; Follow-Up Studies; | 1997 |
Comparison of chlorambucil, azathioprine or cyclophosphamide combined with corticosteroids in the treatment of lupus nephritis.
Topics: Adolescent; Adult; Azathioprine; Child; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dr | 1979 |
[Use of leukeran in the overall therapy of chronic glomerulonephritis in children].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Chronic Disease; Clinical Trials as Topic; Drug E | 1977 |
[Treatment with chlorambucil and azathioprine in primary glomerulonephritis. Results of a "controlled" study].
Topics: Anti-Bacterial Agents; Antihypertensive Agents; Azathioprine; Chlorambucil; Clinical Trials as Topic | 1975 |
Prognosis and treatment of membranous nephropathy.
Topics: Biopsy; Capillaries; Chlorambucil; Clinical Trials as Topic; Complement C3; Cyclophosphamide; Glomer | 1986 |
The advantages of immunosuppressive therapy in renal disease.
Topics: Chlorambucil; Clinical Trials as Topic; Follow-Up Studies; Glomerulonephritis; Humans; Immunosuppres | 1988 |
Clinical and morphologic evolution of idiopathic membranous nephropathy.
Topics: Adolescent; Adult; Aged; Basement Membrane; Biopsy; Chlorambucil; Clinical Trials as Topic; Female; | 1986 |
[New results concerning the effectiveness of therapy of chronic glomerulonephritis. Results of cytostatics-anticoagulants-aggregation inhibitors, cystostatics-anticoagulants-aggregation inhibitors-prednisone and cystostatics-prednisone therapy, derived fr
Topics: Anticoagulants; Chlorambucil; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Drug Thera | 1986 |
[Drug treatment of chronic glomerulonephritis: contra].
Topics: Azathioprine; Chlorambucil; Chronic Disease; Clinical Trials as Topic; Cyclophosphamide; Drug Therap | 1985 |
[Drug treatment of chronic glomerulonephritis: pro].
Topics: Chlorambucil; Chronic Disease; Clinical Trials as Topic; Cyclophosphamide; Cyclosporins; Glomerulone | 1985 |
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
Management of the nephrotic syndrome.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos | 1974 |
76 other studies available for chlorambucil and Bright Disease
| Article | Year |
|---|---|
Nephrotic syndrome due to immunoglobulin M mesangial glomerulonephritis preceding juvenile idiopathic arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Biopsy; Child, Preschool; Chlorambucil; Glomeruloneph | 2013 |
[THE NEPHROTIC SYNDROME OF "RHEUMATOID PURPURA"].
Topics: Abdomen; Abdomen, Acute; Abdominal Cavity; Child; Chlorambucil; Diagnosis; Glomerulonephritis; Hemat | 1964 |
Minimal change glomerulonephritis in chronic lymphocytic leukemia: pathophysiological and therapeutic aspects.
Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Chlorambucil; Drug Combina | 2006 |
[The treatment of the nephrotic syndrome with the aid of immunosuppressive drugs].
Topics: Chlorambucil; Glomerulonephritis; Humans; Immunosuppressive Agents; Nephrotic Syndrome; Prednisone | 1967 |
Azathioprine treatment of immunological renal disease.
Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Cortisone; Female; Glomerulonephritis; Humans; Lupus | 1967 |
[Association of glomerulonephritis in essential mixed cryoglobulinemia with IgA nephropathy. Effect of treatment with plasmapheresis and chlorbutin].
Topics: Chlorambucil; Cryoglobulinemia; Female; Glomerulonephritis; Humans; Immune Complex Diseases; Immunog | 1984 |
A patient with IgA GN with steroid-dependent nephrotic syndrome.
Topics: Chlorambucil; Glomerulonephritis; Humans; Immunoglobulin A; Male; Methylprednisolone; Middle Aged; N | 1984 |
Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil.
Topics: Adult; Chlorambucil; Female; Glomerulonephritis; Humans; Lupus Erythematosus, Systemic; Nephrotic Sy | 1984 |
[Global pancreatic and gastric deficiency after a familial membranous glomerulonephritis in a child treated by corticoids and chlorambucil for a long time (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Chlorambucil; Gastritis; Glomerulonephritis; Humans; Long-Term | 1982 |
[Acute leukaemia during immunosuppressive treatment. One case (author's transl)].
Topics: Blood Cell Count; Chlorambucil; Glomerulonephritis; Humans; Leukemia, Myeloid, Acute; Male; Middle A | 1981 |
Treatment of the idiopathic nephrotic syndrome.
Topics: Alkylating Agents; Child; Chlorambucil; Cyclophosphamide; Drug Resistance; Glomerulonephritis; Human | 1981 |
Primary glomerular disease: to treat or not to treat.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulonephritis; Glomerulosclerosis, | 1982 |
Occurrence of second tumors in man after anticancer drug treatment.
Topics: Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Azathiopri | 1982 |
Simultaneous occurrence of fibrillary glomerulopathy and AL amyloid.
Topics: Amyloid; Amyloidosis; Antineoplastic Agents, Alkylating; Biopsy; Chlorambucil; Follow-Up Studies; Gl | 1998 |
[Possibilities and limitations of immunosuppressive therapy for glomerulonephritis].
Topics: Acute Disease; Antilymphocyte Serum; Azathioprine; Chlorambucil; Chronic Disease; Cyclophosphamide; | 1977 |
Acute leukemia after prolonged immunosuppressive therapy for glomerulonephritis.
Topics: Adolescent; Alkylating Agents; Chlorambucil; Dipyridamole; Glomerulonephritis; Humans; Indomethacin; | 1978 |
Idiopathic membranoproliferative (mesangiocapillary) glomerulonephritis: a clinicopathologic study.
Topics: Adolescent; Adult; Aged; Azathioprine; Child; Chlorambucil; Complement C3; Cyclophosphamide; Drug Th | 1979 |
[Criteria for the outcome of treatment of chronic glomerulonephritis and the evaluation of the effectiveness of current therapeutic methods].
Topics: Adult; Aged; Chlorambucil; Chronic Disease; Drug Evaluation; Female; Glomerulonephritis; Heparin; Hu | 1978 |
[Conservative therapy of chronic glomerulonephritis].
Topics: Acidosis; Azathioprine; Chlorambucil; Chronic Disease; Chronic Kidney Disease-Mineral and Bone Disor | 1978 |
Study of antibody dependent cellular cytotoxicity (ADCC). III. Preliminary findings concerning the influence of immunosuppressive drugs.
Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Azathioprine; Chlorambucil; Drug Therapy, Combination; | 1978 |
Treatment of lupus nephritis.
Topics: Adrenal Cortex Hormones; Adult; Animals; Antibody Formation; Azathioprine; Chlorambucil; Cyclophosph | 1976 |
[Experiences with cytotoxic drugs in therapy of the nephrotic syndrome].
Topics: Adolescent; Adult; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Huma | 1977 |
[Extragonadal complications of chlorambucil in children. Report of 300 cases of glomerulonephritis].
Topics: Adolescent; Adult; Child; Child, Preschool; Chlorambucil; France; Glomerulonephritis; Hematologic Di | 1977 |
Editorial: Four plus: the management of nephrosis.
Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Drug Tolerance; Glomerulonephritis; Humans; Nephrosis; | 1976 |
[Immunosuppressive therapy of diffuse glomerulonephritis in children].
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Drug Evaluation; Female; Glomerulon | 1976 |
[Urgent problems of treatment of glomerulonephritis in childhood].
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Drug Evaluation; Glomerulonephritis; Humans; Pr | 1976 |
[Treatment of primary chronic glomerulonephritis with a triple combination of prednisone, azathioprine and a nitrogen mustard derivative].
Topics: Adolescent; Adult; Azathioprine; Child; Chlorambucil; Cyclophosphamide; Drug Evaluation; Drug Therap | 1975 |
Specificity of SLE serum antibody for single-stranded and double-stranded DNA configuration.
Topics: Adolescent; Ammonium Sulfate; Antibody Specificity; Arthritis, Rheumatoid; Chemical Precipitation; C | 1975 |
[Treatment of chronic glomerulonephritis].
Topics: Anticoagulants; Chlorambucil; Chronic Disease; Dipyridamole; Drug Therapy, Combination; Glomerulonep | 1975 |
[Comparative characteristics of the spectrum of free amino acids of blood serum and urine in children with glomerulonephritis treated with prednisolone, leukeran and anabolic steroids].
Topics: Adolescent; Amino Acids; Anabolic Agents; Child; Child, Preschool; Chlorambucil; Glomerulonephritis; | 1975 |
[Rapidly progressive glomerulonephritis in a child. Clinical and histological observation over 3 1/2 years (author's transl)].
Topics: Acute Disease; Anuria; Biopsy, Needle; Child; Chlorambucil; Glomerular Filtration Rate; Glomerulonep | 1976 |
[Should adult nephrotic syndrome secondary to idiopathic extramembranous glomerulonephritis be treated? An approach by decisional analysis].
Topics: Adrenal Cortex Hormones; Chlorambucil; Glomerulonephritis; Humans; Nephrotic Syndrome | 1992 |
[Adult idiopathic extramembranous glomerulonephritis (EMG): results of treatment with corticoids and chlorambucil].
Topics: Adolescent; Adult; Aged; Chlorambucil; Female; Glomerulonephritis; Humans; Male; Methylprednisolone; | 1992 |
Long-term follow-up in children with steroid-resistant nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Resistance; Female; Follow | 1992 |
Glomerulonephritis in chronic lymphocytic leukemia and related B-cell lymphomas.
Topics: Adult; Aged; Aged, 80 and over; B-Lymphocytes; Chlorambucil; Female; Glomerulonephritis; Glomerulone | 1992 |
[Antiprolifirative effect of chlorbutin and sensitivity of patients with glomerulonephritis to this drug].
Topics: Adolescent; Adult; Alkylating Agents; Cell Division; Child; Chlorambucil; Drug Therapy, Combination; | 1991 |
Predicting the response to cytotoxic therapy for childhood nephrotic syndrome: superiority of response to corticosteroid therapy over histopathologic patterns.
Topics: Adolescent; Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Glo | 1988 |
Long-term effects of steroid and cytostatic treatment on the clinical course of idiopathic membranous glomerulonephritis (retrospective study).
Topics: Adolescent; Adult; Aged; Azathioprine; Chlorambucil; Cyclophosphamide; Drug Administration Schedule; | 1988 |
Treatment of childhood prednisone-resistant nephrotic syndrome and focal segmental glomerulosclerosis with intravenous methylprednisolone and oral alkylating agents.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Resi | 1987 |
[Course and therapy of membranous glomerulonephritis].
Topics: Adult; Chlorambucil; Glomerulonephritis; Humans; Kidney Glomerulus; Methylprednisolone; Prognosis | 1987 |
Treatment of idiopathic membranous nephropathy.
Topics: Chlorambucil; Dose-Response Relationship, Drug; Follow-Up Studies; Glomerulonephritis; Glucocorticoi | 1987 |
[Indications and effectiveness of combined therapy in chronic glomerulonephritis].
Topics: Adolescent; Adult; Anticoagulants; Chlorambucil; Chronic Disease; Dipyridamole; Drug Evaluation; Dru | 1987 |
[Therapy of glomerulonephritis].
Topics: Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Glomerulonephritis; Humans; Prednisone | 1986 |
[Further study of the indications for combination cytostatic-anticoagulant-antiaggregation-corticosteroid therapy of chronic glomerulonephritis].
Topics: Adolescent; Adult; Anticoagulants; Cell Division; Chlorambucil; Chronic Disease; Dipyridamole; Drug | 1985 |
Treatment of lupus nephritis with cyclophosphamide.
Topics: Adolescent; Adult; Age Factors; Azathioprine; Biopsy; Chlorambucil; Cortisone; Cyclophosphamide; Fem | 1970 |
Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults.
Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Cholesterol; Creatinine; Cyclophosphamide; Female; Gl | 1971 |
Mixed cryoglobulins and glomerulonephritis.
Topics: Beta-Globulins; Chlorambucil; Creatinine; Cryoglobulins; Fluorescent Antibody Technique; gamma-Globu | 1968 |
Cryoglobulinemia and disease.
Topics: Adult; Anemia, Hemolytic; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Beta-Globulins | 1970 |
[Wegener's granulomatosis. Contribution to the diagnosis, therapy and course].
Topics: Aged; Chlorambucil; Cyclophosphamide; Female; Glomerulonephritis; Granulomatosis with Polyangiitis; | 1974 |
Focal glomerulosclerosis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyc | 1973 |
[Course of nephropathy in systemic lupus erythematosus . Influence of the treatment on clinical symptoms, renal function and histology].
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antimalarials; Azathioprine; Biopsy; Chlorambucil; | 1972 |
[Nephropathies of rheumatoid purpura in children. Clinical and anatomical study of 60 cases].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Diagnosis, Differential; Female; Fluorescent Anti | 1972 |
Immunologic events preceding clinical exacerbation of systemic lupus erythematosus.
Topics: Adolescent; Antibodies; Chlorambucil; Complement System Proteins; Glomerulonephritis; Humans; Immuno | 1973 |
[Treatment of chronic glomerulopathy].
Topics: Anti-Inflammatory Agents; Azathioprine; Biopsy; Chlorambucil; Chronic Disease; Creatine; Cyclophosph | 1972 |
[Hematopoiesis in patients with diffuse glomerulonephritis treated with cytostatic drugs].
Topics: Adult; Bone Marrow Diseases; Chlorambucil; Female; Glomerulonephritis; Hematopoiesis; Humans; Male | 1972 |
[2 cases of apparently primary glomerulopathies with deposits. Recovery with immunodepressive agents. Secondary onset of an acute S.L.E. without renal involvement].
Topics: Acute Disease; Biopsy; Chlorambucil; Glomerulonephritis; Humans; Inclusion Bodies, Viral; Kidney Glo | 1972 |
Focal necrotizing glomerulonephritis: treatment with prednisone and chlorambucil.
Topics: Adult; Aged; Biopsy; Child; Chlorambucil; Female; Follow-Up Studies; Glomerulonephritis; Humans; Kid | 1973 |
[Pains in the face and jaws, due to Wegener's granuloma (author's transl)].
Topics: Adult; Bone Resorption; Chlorambucil; Facial Neuralgia; Female; Glomerulonephritis; Granulomatosis w | 1973 |
[Differential approach to prescribing of immunodepressive agents to children with nephritis].
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppressive A | 1973 |
Focal necrotizing glomerulonephritis.
Topics: Adolescent; Adult; Aged; Anti-Glomerular Basement Membrane Disease; Biopsy; Blood Urea Nitrogen; Cap | 1973 |
[Studies on experimental hetero-immune nephritis. II. Prevention by immunosuppressive agents and certain anticoagulants].
Topics: Animals; Chlorambucil; Ducks; Glomerulonephritis; Heparin; Hypersensitivity, Immediate; Immune Sera; | 1967 |
[Recovery of normal ultrastructure in 2 cases of primary glomerulonephritis with diffuse extra-membranous deposits].
Topics: Adult; Basement Membrane; Biopsy; Chlorambucil; Female; Glomerulonephritis; Glucocorticoids; Hematur | 1968 |
[Leukeran in the treatment of glomerulonephritis in children].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Glomerulonephritis; Humans; Immunosuppressive Age | 1971 |
[Use of cytostatic drugs for glomerulonephritis in children].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Glomerulonephritis; Humans; Mercaptopurine; Nitro | 1971 |
[Immunodepressive therapy in nephropathies].
Topics: Azathioprine; Chlorambucil; Collagen Diseases; Diabetic Nephropathies; Glomerulonephritis; Humans; I | 1969 |
[Correlations between the histological changes and results of treatment with corticoids and immunosuppressive agents in primary glomerulonephritis].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Azathioprine; Chlorambucil; Glomerulonephritis; Humans; | 1970 |
[A case of acute glomerulonephritis supposed to be malignant. Complete clinical, biological and histological remission after a combined chlorambucil and indomethacin treatment].
Topics: Acute Disease; Child; Chlorambucil; Diagnosis, Differential; Female; Glomerulonephritis; Humans; Ind | 1970 |
[Primary glomerulopathies--therapy using corticosteroids and cytostatics (immunosuppressive agents)].
Topics: Antineoplastic Agents; Azathioprine; Chlorambucil; Glomerulonephritis; Humans; Immunosuppressive Age | 1970 |
[Experience with using certain cytostatic agents in glomerulonephritis in children].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Chronic Disease; Female; Glomerulonephritis; Huma | 1970 |
[Cytostatic treatment of the steroid-resistant nephrotic syndrome. (Long term study on 24 patients)].
Topics: Adult; Azathioprine; Biopsy; Chlorambucil; Female; Glomerulonephritis; Humans; Kidney Function Tests | 1968 |
[Lupus nephropathies and their treatment].
Topics: Chlorambucil; Glomerulonephritis; Humans; Kidney Diseases; Lupus Erythematosus, Systemic; Prednisolo | 1968 |
[Results of immunosuppressive treatment of diseases of renal glomerulus in children].
Topics: Azathioprine; Child; Child, Preschool; Chlorambucil; Chronic Disease; Female; Glomerulonephritis; Hu | 1969 |
[Attempts of the use of cytostatic agents in some forms of glomerulonephritis in children].
Topics: Adolescent; Antineoplastic Agents; Azathioprine; Child; Child, Preschool; Chlorambucil; Chronic Dise | 1969 |
[Therapeutic possibilities in chronic glomerulonephritis].
Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Chronic Disease; Glomerulonephritis; Humans; Immunosu | 1969 |
[Extended chemotherapy of nephrotic syndromes and of certain glomerular nephropathies].
Topics: Chlorambucil; Glomerulonephritis; Humans; Mechlorethamine; Nephrotic Syndrome | 1965 |
Cytotoxic drugs in steroid-resistant renal disease. Alkylating and antimetabolic agents in the treatment of nephrotic syndrome, lupus nephritis, chronic glomerulonephritis, and purpura nephritis in children.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosp | 1966 |