chlorambucil has been researched along with Bone Marrow Diseases in 11 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Bone Marrow Diseases: Diseases involving the BONE MARROW.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disease progression was significantly more frequent in patients presenting an immunological event or an M component." | 2.41 | Treatment of splenic marginal zone B-cell lymphoma: an analysis of 81 patients. ( Arcache, J; Arnaud, P; Berger, F; Callet-Bauchu, E; Coiffier, B; Dumontet, C; Felman, P; Hequet, O; Salles, G; Thieblemont, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmitt, B | 1 |
| Wendtner, CM | 1 |
| Bergmann, M | 1 |
| Busch, R | 1 |
| Franke, A | 1 |
| Pasold, R | 1 |
| Schlag, R | 1 |
| Hopfinger, G | 1 |
| Hiddemann, W | 1 |
| Emmerich, B | 1 |
| Hallek, M | 1 |
| Thieblemont, C | 1 |
| Felman, P | 1 |
| Berger, F | 1 |
| Dumontet, C | 1 |
| Arnaud, P | 1 |
| Hequet, O | 1 |
| Arcache, J | 1 |
| Callet-Bauchu, E | 1 |
| Salles, G | 1 |
| Coiffier, B | 1 |
| Wang, AY | 1 |
| Li, PK | 1 |
| Lai, FM | 1 |
| Chow, KM | 1 |
| Szeto, CC | 1 |
| Leung, CB | 1 |
| Lui, SF | 1 |
| Selby, P | 1 |
| Patel, P | 1 |
| Milan, S | 1 |
| Meldrum, M | 1 |
| Mansi, J | 1 |
| Mbidde, E | 1 |
| Brada, M | 1 |
| Perren, T | 1 |
| Forgeson, G | 1 |
| Gore, M | 1 |
| Thumb, N | 1 |
| Shekhter, SIu | 1 |
| Ar'eva, EM | 1 |
| Tsykin, DB | 1 |
| Fairley, GH | 1 |
| Ultmann, JE | 1 |
| Nixon, DD | 1 |
| Currey, HL | 1 |
| Marcolongo, R | 1 |
| Di Paolo, N | 1 |
| Bianco, G | 1 |
| Bravi, A | 1 |
| Ansfield, FJ | 1 |
| Carter, AC | 1 |
| Goldenberg, IS | 1 |
| Segaloff, A | 1 |
4 reviews available for chlorambucil and Bone Marrow Diseases
| Article | Year |
|---|---|
Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Alemtuzumab; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodie | 2002 |
Treatment of splenic marginal zone B-cell lymphoma: an analysis of 81 patients.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combin | 2002 |
The therapy of lymphoma.
Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow Diseases; Chlorambucil; Cyclophosphamide; Cytarab | 1969 |
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; | 1970 |
2 trials available for chlorambucil and Bone Marrow Diseases
| Article | Year |
|---|---|
[Immunosuppressive therapy chronic polyarthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Diseases; Chlorambucil; Clinical Trial | 1972 |
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; | 1970 |
6 other studies available for chlorambucil and Bone Marrow Diseases
| Article | Year |
|---|---|
Severe bone marrow failure associated with the use of alternating steroid with chlorambucil in lupus membranous nephropathy in Chinese.
Topics: Adult; Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Diseases; China; Chlorambucil; Fe | 2001 |
ChlVPP combination chemotherapy for Hodgkin's disease: long-term results.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Mar | 1990 |
[Hematopoiesis in patients with diffuse glomerulonephritis treated with cytostatic drugs].
Topics: Adult; Bone Marrow Diseases; Chlorambucil; Female; Glomerulonephritis; Hematopoiesis; Humans; Male | 1972 |
The treatment of Hodgkin's disease.
Topics: Agranulocytosis; Antineoplastic Agents; Bone Marrow Diseases; Chlorambucil; Drug Combinations; Hodgk | 1972 |
[Clinical usefulness of eticholanolone in the evaluation of bone marrow reserves in patients treated with myelosuppressive drugs and with radiotherapy].
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Bone Marrow Examination | 1969 |
Phase I study of phenesterin (NSC-104469).
Topics: Administration, Oral; Adult; Aged; Androgens; Antineoplastic Agents; Blood Cell Count; Blood Platele | 1971 |