chlorambucil has been researched along with Bone Loss, Osteoclastic in 3 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with chlorambucil resulted in normalization of the peripheral blood smear, but the malignant infiltration of the bone marrow continued and manifested itself by appearance of new osteolytic lesions, though some of the old lesions underwent recalcification after treatment." | 1.26 | Macroglobulinemia of Waldenström associated with severe osteolytic lesions. ( Krausz, Y; Zlotnick, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DUMA, RJ | 1 |
| BOYETT, JD | 1 |
| BEETHAM, WP | 1 |
| Krausz, Y | 1 |
| Zlotnick, A | 1 |
| von Domarus, H | 1 |
3 other studies available for chlorambucil and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
MEDICAL GRAND ROUNDS FROM THE UNIVERSITY OF ALABAMA MEDICAL CENTER.
Topics: Beta-Globulins; Blood Protein Disorders; Bone Marrow Examination; Bone Resorption; Chlorambucil; Dia | 1964 |
Macroglobulinemia of Waldenström associated with severe osteolytic lesions.
Topics: Aged; Bone Resorption; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Osteolysis; Waldenstrom Mac | 1977 |
[Pains in the face and jaws, due to Wegener's granuloma (author's transl)].
Topics: Adult; Bone Resorption; Chlorambucil; Facial Neuralgia; Female; Glomerulonephritis; Granulomatosis w | 1973 |