chlorambucil has been researched along with Bone Cancer in 11 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized study compared the response of patients with multiple myeloma to chlorambucil, melphalan, and azathioprine." | 5.04 | Treatment of myeloma. Comparison of melphalan, chlorambucil, and azathioprine. ( , 1975) |
| " Progressive severe pancytopenia due to the diffuse bone marrow infiltration led to life-threatening infections following oral chlorambucil treatment." | 3.72 | Remarkable response to rituximab in a patient with atypical CD20(++) mantle cell lymphoma of the bone marrow leading to severe pancytopenia. ( Ho, AD; Kraemer, A; Seggewiss, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aktan, M | 1 |
| Akkaya, A | 1 |
| Doğan, O | 1 |
| Dincol, G | 1 |
| Seggewiss, R | 1 |
| Ho, AD | 1 |
| Kraemer, A | 1 |
| Smith, PJ | 1 |
| Ekert, H | 1 |
| Campbell, PE | 1 |
| Farmer, W | 1 |
| Ravin, C | 1 |
| Schachter, EN | 1 |
| Donat, J | 1 |
| Fernández-Delgado, R | 1 |
| Fernández, L | 1 |
| Jubert, A | 1 |
| Dargent, M | 1 |
| Pommatau, E | 1 |
| Brunat, M | 1 |
| Astaldi, G | 1 |
| Meardi, G | 1 |
| Yalçin, B | 1 |
| Osterberg, G | 1 |
| Rausing, A | 1 |
| Stern, OS | 1 |
| Tulgan, H | 1 |
| Budnitz, J | 1 |
| Haidak, G | 1 |
| Jenkin, RD | 1 |
1 trial available for chlorambucil and Bone Cancer
| Article | Year |
|---|---|
Treatment of myeloma. Comparison of melphalan, chlorambucil, and azathioprine.
Topics: Azathioprine; Blood Urea Nitrogen; Bone Neoplasms; Chlorambucil; Drug Therapy, Combination; Fluoxyme | 1975 |
10 other studies available for chlorambucil and Bone Cancer
| Article | Year |
|---|---|
Chronic lymphocytic leukemia and multiple myeloma in the same patient: case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Neoplasms; Chlorambucil; C | 2003 |
Remarkable response to rituximab in a patient with atypical CD20(++) mantle cell lymphoma of the bone marrow leading to severe pancytopenia.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic | 2004 |
Improved prognosis in disseminated histiocytosis.
Topics: Adolescent; Bone Neoplasms; Child; Child, Preschool; Chlorambucil; Female; Humans; Infant; Liver Neo | 1976 |
Hyperlucent lung after radiation therapy.
Topics: Angiography; Bone Neoplasms; Breast Neoplasms; Chlorambucil; Dyspnea, Paroxysmal; Female; Humans; Lu | 1975 |
[Histiocytosis X: localized and disseminated forms. Apropos of 13 cases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child, Preschool; Chlorambucil; Comb | 1986 |
[Apropos of an experience with the polychemotherapy of cancer].
Topics: Adult; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Dysgermi | 1968 |
[Medical treatment of multiple myeloma].
Topics: Antineoplastic Agents; Bone Neoplasms; Chlorambucil; Humans; Melphalan; Multiple Myeloma | 1973 |
Reticulum cell sarcoma in Waldenström's macroglobulinemia after chlorambucil treatment.
Topics: Amyloidosis; Bone Marrow Cells; Bone Neoplasms; Chlorambucil; Female; Humans; Lymphoma, Non-Hodgkin; | 1970 |
Endobronchial presentation of malignant lymphoma.
Topics: Bone Neoplasms; Bronchial Neoplasms; Bronchoscopy; Chlorambucil; Hodgkin Disease; Humans; Male; Mech | 1968 |
Ewing's sarcoma a study of treatment methods.
Topics: Adolescent; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Mechloretha | 1966 |