chlorambucil has been researched along with Bladder Cancer in 12 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Data on the possible increased risk of malignancy in rheumatoid arthritis are still being collected, and until further information is available, the use of immunosuppressive drugs, particularly alkylating agents, in the treatment of rheumatoid arthritis should be reserved for patients with severe progressive disease or life-threatening complications." | 1.27 | Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens. ( Hazleman, B, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gedon, J | 1 |
| Kehl, A | 1 |
| Aupperle-Lellbach, H | 1 |
| von Bomhard, W | 1 |
| Schmidt, JM | 1 |
| Schrempp, DR | 1 |
| Childress, MO | 1 |
| Stewart, JC | 1 |
| Leach, TN | 1 |
| Tan, KM | 1 |
| Abbo, AH | 1 |
| de Gortari, AE | 1 |
| Bonney, PL | 1 |
| Knapp, DW | 1 |
| BOYLAND, E | 1 |
| KINDER, CH | 1 |
| WILLIAMS, K | 1 |
| Froehner, M | 1 |
| Haase, M | 1 |
| Hakenberg, OW | 1 |
| Wirth, MP | 1 |
| Farr, MJ | 1 |
| Newling, DW | 1 |
| Raper, C | 1 |
| Belman, AB | 1 |
| Baum, ES | 1 |
| Hall, RR | 1 |
| Calvert, AH | 1 |
| De Stavola, B | 1 |
| Freedman, LS | 1 |
| Goodman, S | 1 |
| Kaye, S | 1 |
| Rogers, AC | 1 |
| Nasu, Y | 2 |
| Saegusa, M | 2 |
| Hara, M | 2 |
| Ochi, J | 2 |
| Akagi, T | 2 |
| Obama, T | 2 |
| Tsushima, T | 2 |
| Yoshimoto, J | 2 |
| Ozaki, Y | 1 |
| Matsumura, Y | 2 |
| Ohmori, H | 1 |
| Hazleman, B | 1 |
| Berenbaum, MC | 1 |
| Sheard, CE | 1 |
| Reittie, JR | 1 |
| Bundick, RV | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
1 trial available for chlorambucil and Bladder Cancer
| Article | Year |
|---|---|
Metronomic administration of chlorambucil for treatment of dogs with urinary bladder transitional cell carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Chlorambucil; Dog Diseases; Dogs; Drug | 2013 |
11 other studies available for chlorambucil and Bladder Cancer
| Article | Year |
|---|---|
BRAF mutation status and its prognostic significance in 79 canine urothelial carcinomas: A retrospective study (2006-2019).
Topics: Animals; Carcinoma, Transitional Cell; Chlorambucil; Dog Diseases; Dogs; Female; Male; Meloxicam; Mi | 2022 |
THE TREATMENT OF CARCINOMA IN DOGS' BLADDERS WITH CYTOTOXIC DRUGS.
Topics: Alkylating Agents; Antineoplastic Agents; Carcinogens; Carcinoma; Chlorambucil; Cyclophosphamide; Do | 1965 |
Urinary immunocytology for primary bladder B cell lymphoma.
Topics: Aged; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocy | 2004 |
Simple chemotherapy for bladder lymphoma with bilateral hydronephrosis.
Topics: Chlorambucil; Humans; Hydronephrosis; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prednisolone; Urinar | 1978 |
Current trends in treatment of childhood rhabdomyosarcoma of lower genitourinary tract.
Topics: Biopsy, Needle; Child; Child, Preschool; Chlorambucil; Dactinomycin; Humans; Infant; Male; Prostatic | 1976 |
Phase II trials in metastatic bladder cancer.
Topics: Aged; Antineoplastic Agents; Carboplatin; Chlorambucil; Drug Evaluation; Humans; Neoplasm Metastasis | 1986 |
[A new anti-cancer agent, bestrabucil (KM 2210): I. Concentration in the serum and tissue in urogenital tumors].
Topics: Administration, Oral; Chlorambucil; Estradiol; Humans; Kidney Neoplasms; Male; Prostatic Neoplasms; | 1987 |
[Clinical effects of bestrabucil (KM2210) in bladder cancer].
Topics: Chlorambucil; Drug Administration Schedule; Estradiol; Humans; Male; Middle Aged; Urinary Bladder Ne | 1987 |
Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Cystitis; Humans; Immunosuppres | 1985 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; | 1974 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |