chlorambucil has been researched along with Besnier-Boeck Disease in 14 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1) PURPOSE: To demonstrate usefulness of chlorambucil in patients with severe sarcoidosis unresponsive to, or intolerant of, corticosteroids." | 7.68 | Chlorambucil treatment of sarcoidosis. ( Israel, HL; McComb, BL, 1991) |
| "Ten patients with biopsy-proven sarcoidosis with progressive disease were treated with chlorambucil alone or in combination with corticosteroids." | 7.66 | Chlorambucil in sarcoidosis. ( Kataria, YP, 1980) |
| "The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate." | 4.84 | Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007) |
| "1) PURPOSE: To demonstrate usefulness of chlorambucil in patients with severe sarcoidosis unresponsive to, or intolerant of, corticosteroids." | 3.68 | Chlorambucil treatment of sarcoidosis. ( Israel, HL; McComb, BL, 1991) |
| "Ten patients with biopsy-proven sarcoidosis with progressive disease were treated with chlorambucil alone or in combination with corticosteroids." | 3.66 | Chlorambucil in sarcoidosis. ( Kataria, YP, 1980) |
| "Prednisone dosage was successfully tapered to 10 to 20 mg/d without worsening symptoms in 10 (38%) of the 26 patients studied." | 2.68 | Therapeutic considerations in patients with refractory neurosarcoidosis. ( Agbogu, BN; Sewell, C; Stern, BJ; Yang, G, 1995) |
| "Sarcoidosis is a systemic granulomatous disease that the epidemiology remains unknown." | 2.41 | [Non-steroid therapy for sarcoidosis]. ( Konishi, M; Takahashi, K; Yoneda, K; Yoshimoto, E, 2002) |
| "Chlorambucil was effective on both diseases." | 2.38 | [Association of sarcoidosis and Waldenström's macroglobulinemia]. ( Boulitrop-Morvan, C; Camus, P; Collet, E; Dalac, S; Lambert, D, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Konishi, M | 1 |
| Yoneda, K | 1 |
| Takahashi, K | 1 |
| Yoshimoto, E | 1 |
| RAEVSKII, IG | 1 |
| Badgwell, C | 1 |
| Rosen, T | 1 |
| Hughes, GS | 1 |
| Kataria, YP | 2 |
| O'Brien, TF | 1 |
| Chanda, JJ | 1 |
| Callen, JP | 1 |
| Sahgal, SM | 1 |
| Sharma, OP | 1 |
| Agbogu, BN | 1 |
| Stern, BJ | 1 |
| Sewell, C | 1 |
| Yang, G | 1 |
| Collet, E | 1 |
| Boulitrop-Morvan, C | 1 |
| Dalac, S | 1 |
| Camus, P | 1 |
| Lambert, D | 1 |
| Israel, HL | 3 |
| McComb, BL | 1 |
| Palazzo, E | 1 |
| Oberling, F | 1 |
| North, ML | 1 |
| Lang, JM | 1 |
| Mayer, S | 1 |
| Waitz, R | 1 |
| Westcott, JL | 1 |
| Noehren, TH | 1 |
| Goldstein, RA | 1 |
| Becker, KL | 1 |
| Moore, CF | 1 |
3 reviews available for chlorambucil and Besnier-Boeck Disease
| Article | Year |
|---|---|
[Non-steroid therapy for sarcoidosis].
Topics: Anti-Inflammatory Agents; Antimalarials; Azathioprine; Chlorambucil; Chloroquine; Cyclophosphamide; | 2002 |
Cutaneous sarcoidosis therapy updated.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents | 2007 |
[Association of sarcoidosis and Waldenström's macroglobulinemia].
Topics: Chlorambucil; Female; Humans; Middle Aged; Sarcoidosis; Skin Diseases; Waldenstrom Macroglobulinemia | 1992 |
2 trials available for chlorambucil and Besnier-Boeck Disease
| Article | Year |
|---|---|
Therapeutic considerations in patients with refractory neurosarcoidosis.
Topics: Adult; Azathioprine; Chlorambucil; Cyclophosphamide; Cyclosporine; Female; Humans; Immunosuppressive | 1995 |
The treatment of sarcoidosis.
Topics: Chlorambucil; Clinical Trials as Topic; Humans; Methotrexate; Placebos; Prednisone; Sarcoidosis | 1970 |
9 other studies available for chlorambucil and Besnier-Boeck Disease
| Article | Year |
|---|---|
[EXPERIENCE IN THE USE OF CHLORBUTENE IN LYMPHOGRANULOMATOSIS].
Topics: Chlorambucil; Hodgkin Disease; Sarcoidosis | 1963 |
Sarcoidosis presenting as biliary cirrhosis: treatment with chlorambucil.
Topics: Chlorambucil; Diabetes Mellitus, Type 1; Diagnosis, Differential; Humans; Liver; Liver Cirrhosis, Bi | 1983 |
Necrotizing vasculitis (angiitis) with granulomatosis.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Granuloma, Lethal Midline; Gr | 1984 |
Fatal herpes simplex infection during chlorambucil therapy for sarcoidosis.
Topics: Chlorambucil; Female; Herpes Simplex; Humans; Lung Diseases; Middle Aged; Sarcoidosis | 1984 |
Chlorambucil in sarcoidosis.
Topics: Adult; Chlorambucil; Dermatitis; Drug Therapy, Combination; Female; Humans; Lung Diseases; Middle Ag | 1980 |
Chlorambucil treatment of sarcoidosis.
Topics: Adult; Chlorambucil; Female; Humans; Lung; Male; Middle Aged; Radiography; Sarcoidosis; Sarcoidosis, | 1991 |
Sarcoidosis in a patient with cold haemagglutinin disease.
Topics: Adult; Agglutinins; Anemia, Hemolytic, Autoimmune; Autoantibodies; Azathioprine; Bronchi; Chlorambuc | 1972 |
Bronchial stenosis in chronic sarcoidosis.
Topics: Aged; Airway Obstruction; Bronchial Diseases; Chlorambucil; Constriction; Female; Humans; Middle Age | 1973 |
The infrequency of hypercalcemia in sarcoidosis.
Topics: Adolescent; Adult; Blood Proteins; Chlorambucil; Female; Filtration; Humans; Hypercalcemia; Magnesiu | 1971 |