chlorambucil has been researched along with Bacterial Disease in 6 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with hairy cell leukemia have a significant susceptibility to infections that can affect morbidity and mortality." | 1.27 | Infectious complications in 127 patients with hairy cell leukemia. ( Golomb, HM; Hadad, LJ, 1984) |
| "Azathioprine was best tolerated, but gave only medium results whereas procarbazine, as a very potent drug, had the highest rate of side effects (especially depression of bone marrow, infections, gastrointestinal manifestations etc." | 1.25 | [Side effects in immunosuppressive therapy]. ( Thumb, N, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Golomb, HM | 1 |
| Hadad, LJ | 1 |
| Pascual, JF | 1 |
| Molina, M | 1 |
| Lopez, J | 1 |
| Wiltshaw, E | 1 |
| Thumb, N | 1 |
| Cayla, J | 1 |
| Rondier, J | 1 |
| Deshayes, P | 1 |
| Rénier, JC | 1 |
| Bregeon, C | 1 |
| Houdent, G | 1 |
1 review available for chlorambucil and Bacterial Disease
| Article | Year |
|---|---|
Chemotherapy in chronic lymphocytic leukaemia.
Topics: Adrenal Cortex Hormones; Bacterial Infections; Bone Marrow; Cell Transformation, Neoplastic; Chloram | 1977 |
5 other studies available for chlorambucil and Bacterial Disease
| Article | Year |
|---|---|
Infectious complications in 127 patients with hairy cell leukemia.
Topics: Bacterial Infections; Blood Cell Count; Chlorambucil; Humans; Leukemia, Hairy Cell; Splenectomy | 1984 |
Long-term assessment of chlorambucil in children with nephrotic syndrome who fail to respond adequately to corticosteroids.
Topics: Adolescent; Anemia; Bacterial Infections; Child; Child, Preschool; Chlorambucil; Drug Resistance; Fe | 1981 |
[Side effects in immunosuppressive therapy].
Topics: Alopecia; Amenorrhea; Anemia; Azathioprine; Bacterial Infections; Chlorambucil; Female; Humans; Immu | 1975 |
[Treatment of 67 rheumatoid polyarthritis cases with chlorambucil].
Topics: Adult; Age Factors; Aged; Amenorrhea; Arthritis, Rheumatoid; Bacterial Infections; Blood Cell Count; | 1971 |
[Complications and sequelae of immunosuppressive therapy of rheumatoid arthritis].
Topics: Alopecia; Amenorrhea; Anemia; Arthritis, Rheumatoid; Bacterial Infections; Chlorambucil; Cyclophosph | 1971 |