chlorambucil has been researched along with Ascites in 12 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Ascites: Accumulation or retention of free fluid within the peritoneal cavity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorambucil treatment also caused morphological abnormalities in red blood cells, majority of which include acanthocytes, burr and microcystis." | 5.40 | Chlorambucil and ascorbic acid-mediated anticancer activity and hematological toxicity in Dalton's ascites lymphoma-bearing mice. ( Kalita, S; Prasad, SB; Verma, AK, 2014) |
| "Chlorambucil treatment also caused morphological abnormalities in red blood cells, majority of which include acanthocytes, burr and microcystis." | 1.40 | Chlorambucil and ascorbic acid-mediated anticancer activity and hematological toxicity in Dalton's ascites lymphoma-bearing mice. ( Kalita, S; Prasad, SB; Verma, AK, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalita, S | 1 |
| Verma, AK | 1 |
| Prasad, SB | 1 |
| ZELENIK, JS | 1 |
| HALPERN, AJ | 1 |
| WILLIAMS, DW | 1 |
| LEBHERZ, TB | 1 |
| HUSTON, JW | 1 |
| AUSTIN, JA | 1 |
| BOYCE, CR | 1 |
| PALLESCHI, M | 1 |
| Riches, PG | 1 |
| Gascoigne, EW | 1 |
| Leese, CL | 1 |
| Harrap, KR | 1 |
| Kelsey, PR | 1 |
| Geary, CG | 1 |
| Villasanta, U | 1 |
| Bloedorn, FG | 1 |
| Clark, DG | 1 |
| Hilaris, BS | 1 |
| Ochoa, M | 1 |
| Freel, JH | 1 |
| Speckhard, ME | 1 |
| Hurley, JD | 1 |
| Fetherston, WC | 1 |
| Grueninger, AJ | 1 |
| Julian, CG | 1 |
| Woodruff, JD | 1 |
| McCann, WJ | 1 |
| Cappelletti, RR | 1 |
| Neumann, CG | 1 |
| Papavasiliou, A | 1 |
| Sfikakis, P | 1 |
| Nicolaidis, C | 1 |
2 reviews available for chlorambucil and Ascites
| Article | Year |
|---|---|
Management of idiopathic myelofibrosis.
Topics: Anemia; Ascites; Blood Coagulation Disorders; Bone Marrow; Busulfan; Chlorambucil; Humans; Hypertens | 1987 |
The role of chemotherapy in the treatment of primary ovarian malignancy.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Ascites; Chlorambucil; Chromium; DNA Repl | 1969 |
10 other studies available for chlorambucil and Ascites
| Article | Year |
|---|---|
Chlorambucil and ascorbic acid-mediated anticancer activity and hematological toxicity in Dalton's ascites lymphoma-bearing mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascites; Ascorbic Acid; Blood Ce | 2014 |
TREATMENT OF NEOPLASTIC EFFUSIONS WITH CHLORAMBUCIL.
Topics: Ascites; Chlorambucil; Female; Humans; Neoplasms; Ovarian Neoplasms; Pharmacology; Pleural Effusion; | 1964 |
SUSTAINED PALLIATION IN OVARIAN CARCINOMA.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Carcinoma; Chlorambucil; Dysgerminoma; Female; Gr | 1965 |
[FINDINGS ON A CASE OF CHRONIC LYMPHATIC LEUKOSIS WITH ASCITES AND ITS THERAPY].
Topics: Ascites; Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid | 1965 |
The effects of chlorambucil on the utilization of exogenous thymidine by tumour cells.
Topics: Alkylating Agents; Animals; Ascites; Cells, Cultured; Chlorambucil; DNA, Neoplasm; Neoplasm Transpla | 1975 |
Operation, external irradiation, radioactive isotopes, and chemotherapy in treatment of metastatic ovarian malignancies.
Topics: Ascites; Carcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Follow-Up St | 1968 |
Interdisciplinary approach to advanced ovarian cancer.
Topics: Alkylating Agents; Ascites; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Fluoroura | 1974 |
Integrated therapy in the treatment of ovarian cancer with surgery, radiation and chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Chlorambucil; Cobalt Isotopes; Cyclophosphamide; | 1972 |
Ileo-entectropy for ascites associated with ovarian tumors.
Topics: Ascites; Ascitic Fluid; Chlorambucil; Female; Humans; Ileum; Methods; Middle Aged; Ovarian Neoplasms | 1968 |
[Treatment of ascites associated with advanced ovarian cancer].
Topics: Ascites; Carcinoma; Chlorambucil; Female; Humans; Ovarian Neoplasms | 1968 |