chlorambucil has been researched along with Anti-Glomerular Basement Membrane Disease in 7 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Anti-Glomerular Basement Membrane Disease: An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simon, NM | 1 |
| Rosenberg, MJ | 1 |
| Pokorny, CS | 1 |
| Adler, GF | 1 |
| Méry, JP | 1 |
| Girard, JF | 1 |
| Johnson, JR | 1 |
| McGovern, VJ | 1 |
| Cameron, JS | 1 |
| Seaton, A | 1 |
| Meland, JM | 1 |
| Lapp, NL | 1 |
| Del Río, G | 1 |
| Elizalde, C | 1 |
2 reviews available for chlorambucil and Anti-Glomerular Basement Membrane Disease
| Article | Year |
|---|---|
Medical treatment of glomerular diseases.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Child; Chlorambucil; Cyclophosphamid | 1978 |
Immunosuppressant agents in the treatment of glomerulonephritis. 2. Cytotoxic drugs.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antilymphocyte Serum; Antineoplastic Agents; Azath | 1971 |
5 other studies available for chlorambucil and Anti-Glomerular Basement Membrane Disease
| Article | Year |
|---|---|
Hodgkin's disease occurring in a patient treated successfully for Goodpasture's syndrome.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Chlorambucil; Hodgkin Disease; Humans; Male; Predn | 1988 |
[Indications for immunosuppressive agents in glomerular nephropathies].
Topics: Adrenal Cortex Hormones; Anti-Glomerular Basement Membrane Disease; Azathioprine; Chlorambucil; Cycl | 1974 |
Focal necrotizing glomerulonephritis.
Topics: Adolescent; Adult; Aged; Anti-Glomerular Basement Membrane Disease; Biopsy; Blood Urea Nitrogen; Cap | 1973 |
Remission in Goodpasture's syndrome: report of two patients treated by immunosuppression and review of the literature.
Topics: Anti-Glomerular Basement Membrane Disease; Azathioprine; Chlorambucil; Humans; Immunosuppression The | 1971 |
[Good pasture's syndrome. Treatment in 2 new cases. Remission].
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Biopsy; Chlorambucil; Female; Glucoc | 1969 |