chlorambucil has been researched along with Anorexia in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With long-term administration (the longest term, 20 weeks, 36 patients), the dose-limiting factor was concluded to be a decrease in the peripheral leukocyte count when the total amount administered reached about 10 g." | 1.27 | [Phase I study of bestrabucil (KM 2210)]. ( Agatsuma, T; Fugiwara, A; Fujita, K; Goto, T; Isurugi, K; Kamei, H; Kubota, T; Nakao, I; Suga, S; Takenaka, K, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamei, H | 1 |
| Takenaka, K | 1 |
| Goto, T | 1 |
| Suga, S | 1 |
| Fugiwara, A | 1 |
| Nakao, I | 1 |
| Agatsuma, T | 1 |
| Fujita, K | 1 |
| Isurugi, K | 1 |
| Kubota, T | 1 |
1 other study available for chlorambucil and Anorexia
| Article | Year |
|---|---|
[Phase I study of bestrabucil (KM 2210)].
Topics: Adult; Aged; Animals; Anorexia; Chlorambucil; Dose-Response Relationship, Drug; Drug Administration | 1986 |