chlorambucil has been researched along with Anemia, Hemolytic in 20 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of marginal zone lymphoma complicated by CAIA that responded to rituximab after failing to respond to corticosteroids and chlorambucil." | 3.72 | Refractory cold agglutinin-immunohaemolytic anaemia associated to marginal zone lymphoma responding to rituximab. ( Clavo, M; de Sevilla, AF; Domingo-Doménech, E; González-Barca, E; Grañena, A; Petit, J, 2003) |
| "Castleman disease is a rare cause of lymphoid hyperplasia and may result in localized symptoms or an aggressive, multisystem disorder." | 1.48 | Sjögren's and plasma cell variant Castleman disease: a case report. ( Abrahams, AD; Dei-Adomakoh, YA; Dey, DI; Quarcoopome, L; Segbefia, CI, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dei-Adomakoh, YA | 1 |
| Quarcoopome, L | 1 |
| Abrahams, AD | 1 |
| Segbefia, CI | 1 |
| Dey, DI | 1 |
| van Gaalen, FA | 1 |
| Zanin, DE | 1 |
| Brand, A | 1 |
| Smolej, L | 1 |
| Belada, D | 1 |
| Cermanová, M | 1 |
| Maisnar, V | 1 |
| Lunáková, E | 1 |
| BURNINGHAM, RA | 1 |
| RESTREPO, A | 1 |
| PUGH, RP | 1 |
| BROWN, EB | 1 |
| SCHLOSSMAN, SF | 1 |
| KHURI, PD | 1 |
| LESSNER, HE | 1 |
| HARRINGTON, WJ | 1 |
| OLESEN, H | 2 |
| Petit, J | 1 |
| Clavo, M | 1 |
| de Sevilla, AF | 1 |
| González-Barca, E | 1 |
| Domingo-Doménech, E | 1 |
| Grañena, A | 1 |
| Dearden, C | 1 |
| Wade, R | 1 |
| Else, M | 1 |
| Richards, S | 1 |
| Milligan, D | 1 |
| Hamblin, T | 1 |
| Catovsky, D | 1 |
| Kay, LA | 1 |
| Saunders, PW | 1 |
| Horler, AR | 1 |
| Proctor, SJ | 1 |
| Oken, MM | 1 |
| Griffiths, RW | 1 |
| Williams, RC | 1 |
| Reimann, BE | 1 |
| Wuhrmann, F | 1 |
| Märki, HH | 1 |
| Hippe, E | 1 |
| Jensen, KB | 1 |
| Lind, K | 1 |
| Thomsen, PE | 1 |
| Pronk, EA | 1 |
| Elkerbout, F | 1 |
| Klein, F | 1 |
| Radema, H | 1 |
| Cleton, FJ | 1 |
| Barnett, EV | 1 |
| Bluestone, R | 1 |
| Cracchiolo, A | 1 |
| Goldberg, LS | 1 |
| Kantor, GL | 1 |
| McIntosh, RM | 1 |
| Evans, RS | 1 |
| Baxter, E | 1 |
| Gilliland, BC | 1 |
| Stojcevski, T | 1 |
| Romeo, JA | 1 |
| Schmidt, RB | 1 |
| Klemm, D | 1 |
| Poth, JL | 1 |
| Sharp, GS | 1 |
| Schrier, SL | 1 |
| Marie, J | 1 |
| Lévèque, B | 1 |
| Courtecuisse, V | 1 |
| Debauchez, C | 1 |
| Desbois, JC | 1 |
| Momenzadeh, A | 1 |
2 trials available for chlorambucil and Anemia, Hemolytic
| Article | Year |
|---|---|
The prognostic significance of a positive direct antiglobulin test in chronic lymphocytic leukemia: a beneficial effect of the combination of fludarabine and cyclophosphamide on the incidence of hemolytic anemia.
Topics: Aged; Anemia, Hemolytic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlo | 2008 |
Therapy of macroglobulinaemia. Comparison of the effect of therapy on the level of monoclonal immunoglobulins and on clinical symptoms in four cases of waldenström's macroglobulinaemia and one case of IgA myeloma.
Topics: Agar; Aged; Alkylating Agents; Anemia, Hemolytic; Blood Coagulation Disorders; Blood Protein Disorde | 1969 |
18 other studies available for chlorambucil and Anemia, Hemolytic
| Article | Year |
|---|---|
Sjögren's and plasma cell variant Castleman disease: a case report.
Topics: Adult; Anemia, Hemolytic; Castleman Disease; Chlorambucil; Diagnosis, Differential; Drug Therapy, Co | 2018 |
Erythrocyte survival tests in cases of anti-AnWj antibodies.
Topics: Anemia, Hemolytic; Blood Group Antigens; Blood Group Incompatibility; Chlorambucil; Coombs Test; Ery | 2009 |
Severe anemia caused by combination of autoimmune hemolysis, pure red cell aplasia and massive bone marrow infiltration in an elderly patient with chronic lymphocytic leukemia: successful treatment with rituximab.
Topics: Aged; Anemia, Hemolytic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas | 2010 |
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia; | 1964 |
CHLORAMBUCIL TREATMENT IN THE COLD AGGLUTININ SYNDROME.
Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Blood Cell Count; Blood Protein Electrophoresis; B | 1964 |
Refractory cold agglutinin-immunohaemolytic anaemia associated to marginal zone lymphoma responding to rituximab.
Topics: Adrenal Cortex Hormones; Aged; Anemia, Hemolytic; Antibodies, Monoclonal; Antibodies, Monoclonal, Mu | 2003 |
Lymphoplasmacytoid lymphoma, associated paraproteinaemia and haemolytic anaemia: a report of 2 cases and review of the literature.
Topics: Anemia, Hemolytic; Chlorambucil; Female; Humans; Immunoglobulin D; Immunoglobulin G; Immunoglobulin | 1983 |
Possible NZB syndrome in man.
Topics: Adult; Agglutinins; Anemia, Hemolytic; Antibodies, Antinuclear; Autoimmune Diseases; Blood Protein E | 1973 |
[Therapy of Waldenström disease].
Topics: Anemia, Hemolytic; Antineoplastic Agents; Blood Viscosity; Chlorambucil; Cyclophosphamide; gamma-Glo | 1968 |
Chlorambucil treatment of patients with cold agglutinin syndrome.
Topics: Aged; Alopecia; Anemia, Hemolytic; Antibodies; Blood Protein Electrophoresis; Chlorambucil; Cryoglob | 1970 |
Cryoglobulinemia and disease.
Topics: Adult; Anemia, Hemolytic; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Beta-Globulins | 1970 |
Chronic hemolytic anemia due to cold agglutinins: a 20-year history of benign gammopathy with response to chlorambucil.
Topics: Agglutinins; Anemia, Hemolytic; Autoantibodies; Bence Jones Protein; Blood Protein Electrophoresis; | 1973 |
Haemolytic anaemia in malignant lymphoreticuloendothelial diseases.
Topics: Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow Examination; Ce | 1974 |
Primary macroglobulinemia: report of a case and clinical discussion.
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic; Blood Proteins; Blood Sedimentation; Chlorambucil; Femal | 1967 |
[Paraproteinemic diseases].
Topics: Anemia, Hemolytic; Blood Protein Disorders; Chlorambucil; Cryoglobulins; Cyclophosphamide; Diagnosis | 1969 |
Pipobroman (Vercyte) - a new antineoplastic drug.
Topics: Anemia, Hemolytic; Antineoplastic Agents; Bone Marrow; Busulfan; Chlorambucil; Gastrointestinal Hemo | 1967 |
Cold agglutinin disease and the nephrotic syndrome.
Topics: Aged; Anemia, Hemolytic; Autopsy; Bone Marrow; Chlorambucil; Coombs Test; Cryoglobulins; Female; Hum | 1970 |
[Hemolytic and uremic syndrome associated with an idiopathic nephrotic syndrome of 4 years' development].
Topics: Anemia, Hemolytic; Biopsy; Child; Chlorambucil; Female; Glucocorticoids; Hemoglobinuria; Humans; Hyp | 1969 |