chlorambucil has been researched along with Anemia, Hemolytic, Autoimmune in 33 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Progressive B-cell chronic lymphocytic leukemia (B-CLL) is often complicated by autoimmune hemolytic anemia (AIHA), which in some cases may be refractory to conventional therapy such as corticosteroids, rituximab and splenectomy." | 1.34 | Treatment of severe refractory autoimmune hemolytic anemia in B-cell chronic lymphocytic leukemia with alemtuzumab (humanized CD52 monoclonal antibody). ( Celsing, F; Hansson, L; Karlsson, C; Lundin, J, 2007) |
| "Fifty-two cases of autoimmune hemolytic anemia (AHA) were observed within a series of 1203 patients (4." | 1.31 | Autoimmune hemolytic anemia in chronic lymphocytic leukemia: clinical, therapeutic, and prognostic features. ( Cerretti, R; Coluzzi, S; Foa, R; Giannarelli, D; Girelli, G; Mandelli, F; Mauro, FR, 2000) |
| "Chlorambucil has been used for many years for the treatment of low-grade B-cell lymphoproliferative disorders, including chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma." | 1.31 | High-dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma. ( Mounter, PJ; Proctor, SJ; Summerfield, GP; Taylor, PR, 2002) |
| "In mild chronic cold agglutinin disease preventing cold exposure usually suffices to avoid disease exacerbation." | 1.29 | [Treatment of severe idiopathic cold-agglutinin diseases using interferon-alpha 2b]. ( Barth, A; Nydegger, U; Rordorf, R; Tobler, A, 1994) |
| "One response, however, did relate that diffuse histiocytic lymphoma developed in three of 141 patients receiving prolonged chlorambucil therapy for polycythemia vera." | 1.26 | Lymphoma in primary chronic cold hemagglutinin disease treated with chlorambucil. ( Chaplin, H, 1982) |
| "Progressive and severe autoimmune hemolytic anemia developed in a patient with chronic lymphocytic leukemia (CLL) despite treatment with chlorambucil, high doses of corticosteroids and attempts to transfuse packed red blood cells." | 1.26 | Specific immunoadsorption of IgG antibody in a patient with chronic lymphocytic leukemia and autoimmune hemolytic anemia. A new form of therapy for the acute critical stage. ( Bassett, JG; Besa, EC; Cooper, DR; Idiculla, A; Joseph, RR; Ray, PK; Rhoads, JE; Swami, VK, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (63.64) | 18.7374 |
| 1990's | 6 (18.18) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Velázquez, D | 1 |
| de Pablo, P | 1 |
| García, D | 1 |
| Ramírez, JR | 1 |
| MOLANDER, DW | 1 |
| LADUE, JS | 1 |
| OLESEN, H | 1 |
| Shvidel, L | 1 |
| Shtalrid, M | 1 |
| Berrebi, A | 1 |
| Sinha, A | 1 |
| Richardson, G | 1 |
| Patel, RT | 1 |
| Karlsson, C | 1 |
| Hansson, L | 1 |
| Celsing, F | 1 |
| Lundin, J | 1 |
| Chaplin, H | 1 |
| Besa, EC | 1 |
| Ray, PK | 1 |
| Swami, VK | 1 |
| Idiculla, A | 1 |
| Rhoads, JE | 1 |
| Bassett, JG | 1 |
| Joseph, RR | 1 |
| Cooper, DR | 1 |
| Economopoulos, T | 1 |
| Stathakis, N | 1 |
| Constantinidou, M | 1 |
| Papageorgiou, E | 1 |
| Anastassiou, C | 1 |
| Raptis, S | 1 |
| Rordorf, R | 1 |
| Barth, A | 1 |
| Nydegger, U | 1 |
| Tobler, A | 1 |
| Emilia, G | 1 |
| Messora, C | 1 |
| Majumdar, G | 1 |
| Brown, S | 1 |
| Slater, NG | 1 |
| Singh, AK | 1 |
| Remenyik, E | 1 |
| Ujj, G | 1 |
| Kiss, A | 1 |
| Kószó, F | 1 |
| Horkay, I | 1 |
| Antich Rojas, J | 1 |
| Balaguer, H | 1 |
| Cladera, A | 1 |
| Mauro, FR | 1 |
| Foa, R | 1 |
| Cerretti, R | 1 |
| Giannarelli, D | 1 |
| Coluzzi, S | 1 |
| Mandelli, F | 1 |
| Girelli, G | 1 |
| Summerfield, GP | 1 |
| Taylor, PR | 1 |
| Mounter, PJ | 1 |
| Proctor, SJ | 1 |
| Schmitt, T | 1 |
| Mathiot, C | 1 |
| Benveniste, M | 1 |
| Varet, B | 1 |
| Levy, JP | 1 |
| Pirofsky, B | 1 |
| Zupańska, B | 1 |
| Sylwestrowicz, T | 1 |
| Rechowicz, K | 1 |
| Górska, B | 1 |
| Pawelski, S | 1 |
| Thompson-Moya, L | 1 |
| Martin, T | 1 |
| Heuft, HG | 1 |
| Neubauer, A | 1 |
| Herrmann, R | 1 |
| Budmiger, H | 1 |
| Rhyner, K | 1 |
| Siegenthaler-Zuber, G | 1 |
| Bollinger, A | 1 |
| Donham, JA | 1 |
| Denning, V | 1 |
| Stacher, A | 1 |
| Delespesse, G | 1 |
| Kennes, B | 1 |
| Duchateau, J | 1 |
| Worlledge, SM | 1 |
| Brain, MC | 1 |
| Cooper, AC | 1 |
| Hobbs, JR | 1 |
| Dacie, JV | 2 |
| André, R | 1 |
| Duhamel, G | 1 |
| Salmon, C | 1 |
| Najman, A | 1 |
| Homberg, JC | 1 |
| Stojcevski, T | 1 |
| Palazzo, E | 1 |
| Oberling, F | 1 |
| North, ML | 1 |
| Lang, JM | 1 |
| Mayer, S | 1 |
| Waitz, R | 1 |
| Zittoun, R | 1 |
| Drox, JP | 1 |
| de Carbonniére, C | 1 |
| Bernadou, A | 1 |
| Bilski-Pasquier, G | 1 |
| Bousser, J | 1 |
| Presant, CA | 1 |
| Wiernik, PH | 1 |
| Serpick, AA | 1 |
| Schumacher, K | 1 |
| Gross, R | 1 |
| Lewis, FB | 1 |
| Schwartz, RS | 1 |
| Dameshek, W | 1 |
1 review available for chlorambucil and Anemia, Hemolytic, Autoimmune
| Article | Year |
|---|---|
[Auto-immune diseases and immunodepressive therapy. II. Current clinical indications].
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Arteritis; Autoimmune | 1974 |
32 other studies available for chlorambucil and Anemia, Hemolytic, Autoimmune
| Article | Year |
|---|---|
Primary cutaneous marginal zone B-cell lymphoma: An atypical case.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Murine-Derived; Antigens, CD; Antineopl | 2010 |
CHRONIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alkylating Agents; Anemia; Anemia, Hemolytic, | 1964 |
CHLORAMBUCIL TREATMENT IN THE COLD AGGLUTININ SYNDROME.
Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Blood Cell Count; Blood Protein Electrophoresis; B | 1964 |
Intractable autoimmune hemolytic anemia in B cell chronic lymphocytic leukemia resolved by Rituximab.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antin | 2004 |
Cold agglutinin related acrocyanosis and paroxysmal haemolysis.
Topics: Anemia, Hemolytic, Autoimmune; Antineoplastic Agents, Alkylating; Chlorambucil; Cyanosis; Diagnosis, | 2005 |
Treatment of severe refractory autoimmune hemolytic anemia in B-cell chronic lymphocytic leukemia with alemtuzumab (humanized CD52 monoclonal antibody).
Topics: Aged; Alemtuzumab; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclonal, Hu | 2007 |
Lymphoma in primary chronic cold hemagglutinin disease treated with chlorambucil.
Topics: Anemia, Hemolytic, Autoimmune; Chlorambucil; Chronic Disease; Cold Temperature; Humans; Lymphoma, La | 1982 |
Specific immunoadsorption of IgG antibody in a patient with chronic lymphocytic leukemia and autoimmune hemolytic anemia. A new form of therapy for the acute critical stage.
Topics: Adsorption; Aged; Anemia, Hemolytic, Autoimmune; Antibody Specificity; Cell Separation; Chlorambucil | 1981 |
Cold agglutinin disease in non-Hodgkin's lymphoma.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; | 1995 |
[Treatment of severe idiopathic cold-agglutinin diseases using interferon-alpha 2b].
Topics: Anemia, Hemolytic, Autoimmune; Bilirubin; Chlorambucil; Combined Modality Therapy; Female; Hemoglobi | 1994 |
Interaction between cyclosporin and chlorambucil.
Topics: Anemia, Hemolytic, Autoimmune; Chlorambucil; Cyclosporine; Drug Interactions; Female; Humans; Leukem | 1993 |
Clinical spectrum of autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Chlorambucil; Cyclophosphamide; Drug Therapy, Com | 1993 |
Porphyria cutanea tarda and chronic lymphoid leukemia.
Topics: Anemia, Hemolytic, Autoimmune; Antineoplastic Agents, Alkylating; Blood Transfusion; Chlorambucil; C | 1996 |
[Selective aplasia of the red-cell series after fludarabine administration in a patient with chronic B-cell lymphatic leukemia].
Topics: Anemia, Hemolytic, Autoimmune; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy | 1997 |
Autoimmune hemolytic anemia in chronic lymphocytic leukemia: clinical, therapeutic, and prognostic features.
Topics: Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antineoplastic Combined Chemotherapy Protoco | 2000 |
High-dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents, Alkylating; Ch | 2002 |
[Auto-immune hemolytic anemia associated with Kaposi's sarcoma. Report of a new case (author's transl)].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Female; Humans; Immune System Diseases; Lymphatic | 1979 |
When autoimmune hemolytic anemia complicates chronic lymphocytic leukemia.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Chlorambucil; Female; Humans; Leukemia, Lymphoid; | 1978 |
[Results of treatment of autoimmune hemolytic anemias].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Alkylating Agents; Anemia, Hemolytic, Autoimmune; | 1978 |
Allergic reaction with immune hemolytic anemia resulting from chlorambucil.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Coombs Test; Drug Hypersensitivity; Female; Human | 1989 |
[Idiopathic cold agglutinin disease. Clinical aspects, therapy and course in 6 patients].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Eryt | 1988 |
Cold agglutinin syndrome: nursing management.
Topics: Acute Disease; Anemia, Hemolytic, Autoimmune; Blood Transfusion; Chlorambucil; Chronic Disease; Comb | 1985 |
[Immunosuppressive therapy in hematology].
Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Myelophthis | 1972 |
Immmunosuppressive drugs in the treatment of autoimmune haemolytic anaemia.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies; Azathioprine; Chlorambucil; Cryoglobulins; gamma-Globulin | 1968 |
[Autoimmune hemolytic anemia with lymphatic nodules in the bone marrow].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow; Bone Marrow Examination; Chlorambu | 1968 |
Clinical immunology and the physician. Blood.
Topics: Adrenocorticotropic Hormone; Anemia, Hemolytic, Autoimmune; Anemia, Macrocytic; Blood Transfusion; C | 1974 |
Haemolytic anaemia in malignant lymphoreticuloendothelial diseases.
Topics: Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow Examination; Ce | 1974 |
Sarcoidosis in a patient with cold haemagglutinin disease.
Topics: Adult; Agglutinins; Anemia, Hemolytic, Autoimmune; Autoantibodies; Azathioprine; Bronchi; Chlorambuc | 1972 |
[The evolution of idiopathic autoimmune hemolytic anemia].
Topics: Age Factors; Anemia, Hemolytic, Autoimmune; Antibodies; Chlorambucil; Cyclophosphamide; Female; Huma | 1973 |
Disseminated extrapulmonary nocardiosis presenting as a renal abscess.
Topics: Abscess; Adult; Anemia, Hemolytic, Autoimmune; Autopsy; Brain Diseases; Chlorambucil; Diagnosis, Dif | 1970 |
[Immunosuppressive treatment of autoantibody anemia and idiopathic thrombocytopenic purpura].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Autoantibodie | 1972 |
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non- | 1966 |