chlorambucil has been researched along with Alveolitis, Extrinsic Allergic in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Alveolitis, Extrinsic Allergic: A common interstitial lung disease caused by hypersensitivity reactions of PULMONARY ALVEOLI after inhalation of and sensitization to environmental antigens of microbial, animal, or chemical sources. The disease is characterized by lymphocytic alveolitis and granulomatous pneumonitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient developed an interstitial pneumonitis while receiving chlorambucil for a chronic lymphocytic leukemia (cumulative dose, 8,340 mg)." | 1.29 | Chlorambucil-associated pneumonitis. ( Clauvel, JP; Couderc, LJ; Crestani, B; Frija, J; Israël-Biet, D; Jaccard, A, 1994) |
| "Chlorambucil has only rarely been implicated in this complication." | 1.26 | Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia. ( Besa, EC; Joseph, RR; Justh, G; Lane, SD, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lane, SD | 1 |
| Besa, EC | 1 |
| Justh, G | 1 |
| Joseph, RR | 1 |
| Crestani, B | 1 |
| Jaccard, A | 1 |
| Israël-Biet, D | 1 |
| Couderc, LJ | 1 |
| Frija, J | 1 |
| Clauvel, JP | 1 |
2 other studies available for chlorambucil and Alveolitis, Extrinsic Allergic
| Article | Year |
|---|---|
Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia.
Topics: Aged; Alveolitis, Extrinsic Allergic; Biopsy; Chlorambucil; Dose-Response Relationship, Drug; Humans | 1981 |
Chlorambucil-associated pneumonitis.
Topics: Alveolitis, Extrinsic Allergic; Bronchoalveolar Lavage Fluid; Chlorambucil; Humans; Leukemia, Lympho | 1994 |