chlorambucil has been researched along with Allergic Alveolitis, Extrinsic in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient developed an interstitial pneumonitis while receiving chlorambucil for a chronic lymphocytic leukemia (cumulative dose, 8,340 mg)." | 1.29 | Chlorambucil-associated pneumonitis. ( Clauvel, JP; Couderc, LJ; Crestani, B; Frija, J; Israël-Biet, D; Jaccard, A, 1994) |
| "Chlorambucil has only rarely been implicated in this complication." | 1.26 | Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia. ( Besa, EC; Joseph, RR; Justh, G; Lane, SD, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lane, SD | 1 |
| Besa, EC | 1 |
| Justh, G | 1 |
| Joseph, RR | 1 |
| Crestani, B | 1 |
| Jaccard, A | 1 |
| Israël-Biet, D | 1 |
| Couderc, LJ | 1 |
| Frija, J | 1 |
| Clauvel, JP | 1 |
2 other studies available for chlorambucil and Allergic Alveolitis, Extrinsic
| Article | Year |
|---|---|
Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia.
Topics: Aged; Alveolitis, Extrinsic Allergic; Biopsy; Chlorambucil; Dose-Response Relationship, Drug; Humans | 1981 |
Chlorambucil-associated pneumonitis.
Topics: Alveolitis, Extrinsic Allergic; Bronchoalveolar Lavage Fluid; Chlorambucil; Humans; Leukemia, Lympho | 1994 |