chlorambucil has been researched along with Agammaglobulinemia in 12 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Agammaglobulinemia: An immunologic deficiency state characterized by an extremely low level of generally all classes of gamma-globulin in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An important biological alteration in chronic lymphocytic leukemia (CLL) is the dysregulation of immunoglobulin production, as a consequence of complex and yet incompletely understood interactions between plasma cells and the neoplastic B-cell clone." | 1.35 | Serum globulins as marker of immune restoration after treatment with high-dose rituximab for chronic lymphocytic leukemia. ( Alexandrescu, DT; Wiernik, PH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, S | 1 |
| Sears, M | 1 |
| Crawford, S | 1 |
| Cicci, C | 1 |
| Diskin, CJ | 1 |
| Alexandrescu, DT | 1 |
| Wiernik, PH | 1 |
| Alfinito, F | 1 |
| Formisano, S | 1 |
| Rotoli, B | 1 |
| Greco, MM | 1 |
| Patakfalvi, A | 1 |
| Richards, F | 1 |
| Spurr, CL | 1 |
| Pajak, TF | 1 |
| Blake, DD | 1 |
| Raben, M | 1 |
| Pinkhas, J | 1 |
| Oliver, I | 1 |
| De Vries, A | 1 |
| Spitzer, SA | 1 |
| Henig, E | 1 |
| Fayemi, AO | 1 |
| Williams, J | 1 |
| Cuttner, J | 1 |
| Cohen, ML | 1 |
| Weiss, EB | 1 |
| Degos, R | 1 |
| Blanchet, P | 1 |
| Rain, JD | 1 |
| Reboul, D | 1 |
| Wright, ES | 1 |
| MacPhee, IW | 1 |
| Lee, SL | 1 |
| Rosner, F | 1 |
| Ruberman, W | 1 |
| Glasberg, S | 1 |
12 other studies available for chlorambucil and Agammaglobulinemia
| Article | Year |
|---|---|
Membranous Glomerulopathy in Hypogammaglobulinemia.
Topics: Agammaglobulinemia; Chlorambucil; gamma-Globulins; Glomerulonephritis, Membranous; Humans; Infusions | 2017 |
Serum globulins as marker of immune restoration after treatment with high-dose rituximab for chronic lymphocytic leukemia.
Topics: Agammaglobulinemia; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine- | 2008 |
Familial leukemia: uncommon type of chronic lymphocytic leukemia in two sisters.
Topics: Agammaglobulinemia; Anemia; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Middle Aged; Prednison | 1982 |
[Prognosis in chronic lymphocytic leukemia].
Topics: Agammaglobulinemia; Chlorambucil; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukocyte Co | 1981 |
Secondary antibody deficiency syndrome in haemoblastosis.
Topics: Agammaglobulinemia; Antibodies; Antigens, Bacterial; Blood Protein Disorders; Blood Proteins; Busulf | 1972 |
Thymic irradiation. An approach to chronic lymphocytic leukemia.
Topics: Adult; Agammaglobulinemia; Aged; Blood Platelets; Blood Protein Electrophoresis; Bone Marrow; Bone M | 1974 |
Pulmonary nocardiosis complicating malignant lymphoma successfully treated with chemotherapy.
Topics: Agammaglobulinemia; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Humans; Lung Diseases; Ly | 1973 |
Systemic Weber-Christian disease and thrombocythemia terminating in reticulum-cell sarcoma.
Topics: Adipose Tissue; Adult; Agammaglobulinemia; Arteritis; Arthritis, Rheumatoid; Autopsy; Blood Platelet | 1974 |
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylam | 1971 |
[Chronic cutaneous herpes during a lymphoid blood disease treated by chemotherapy and corticoids].
Topics: Agammaglobulinemia; Chlorambucil; Herpes Simplex; Humans; Immunosuppression Therapy; Leukemia, Lymph | 1971 |
The effect of lymphocyte depletion and hypogammaglobulinemia on the survival of skin homografts.
Topics: Agammaglobulinemia; Animals; Chlorambucil; Hydrocortisone; Leukocytes; Lymphocytes; Rats; Skin Trans | 1965 |
Mu-chain disease.
Topics: Adult; Agammaglobulinemia; Anemia; Bence Jones Protein; Chlorambucil; Female; Fractures, Bone; Heavy | 1971 |