chlorambucil has been researched along with Adjuvant Arthritis in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with chlorambucil intra-articularly was clearly more effective than with methylprednisolone or 90Y at the doses employed and deserves further study as a potential treatment for chronic synovitis." | 1.29 | Treatment of antigen-induced arthritis in rabbits by the intra-articular injection of methylprednisolone, 90Y or chlorambucil. ( Foong, WC; Green, KL, 1993) |
| "Aminochlorambucil was effective on adjuvant arthritis only and IV b (n = 1) had no activity." | 1.26 | [Chemical reactivity and biological properties of a series of aminochlorambucil derivatives]. ( Bazely, N; Brouilhet, H; Delbarre, F; Marchal, S; Rabaud, M; Redel, J, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Green, KL | 1 |
| Foong, WC | 1 |
| Redel, J | 1 |
| Brouilhet, H | 1 |
| Bazely, N | 1 |
| Marchal, S | 1 |
| Rabaud, M | 1 |
| Delbarre, F | 1 |
2 other studies available for chlorambucil and Adjuvant Arthritis
| Article | Year |
|---|---|
Treatment of antigen-induced arthritis in rabbits by the intra-articular injection of methylprednisolone, 90Y or chlorambucil.
Topics: Animals; Arthritis, Experimental; Chlorambucil; Knee Joint; Methylprednisolone; Rabbits; Yttrium | 1993 |
[Chemical reactivity and biological properties of a series of aminochlorambucil derivatives].
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Experimental; Chlorambucil; Imm | 1978 |