chlorambucil has been researched along with Acute Kidney Injury in 8 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil." | 5.35 | Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia. ( Damaj, G; Gruson, B; Makdassi, R; Roszkiewicz, F; Vaida, I, 2009) |
| "The clinical manifestations were acute renal failure and seizures." | 5.27 | Acute renal failure and seizures associated with chlorambucil overdose. ( Blank, DW; Hudman, C; Nanji, AA; Sanders, HD; Schreiber, DH, 1983) |
| "He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil." | 1.35 | Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia. ( Damaj, G; Gruson, B; Makdassi, R; Roszkiewicz, F; Vaida, I, 2009) |
| "Treatment with prednisolone and cyclophosphamide induced a rapid recovery from acute renal failure." | 1.31 | A case with acute renal failure complicated by Waldenström's macroglobulinemia and cryoglobulinemia. ( Fujigaki, Y; Hishida, A; Ikegaya, N; Sano, K; Suzuki, T; Yonemura, K, 2000) |
| "The clinical manifestations were acute renal failure and seizures." | 1.27 | Acute renal failure and seizures associated with chlorambucil overdose. ( Blank, DW; Hudman, C; Nanji, AA; Sanders, HD; Schreiber, DH, 1983) |
| "In addition, acute renal failure developed in both patients, and myolysis in one." | 1.27 | Purpura fulminans in pneumococcal sepsis. ( Berneman, ZN; Bieger, R; Bridts, C; Buyssens, N; Hautekeete, ML; Peetermans, ME; Stevens, WJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vaida, I | 1 |
| Roszkiewicz, F | 1 |
| Gruson, B | 1 |
| Makdassi, R | 1 |
| Damaj, G | 1 |
| Blank, DW | 1 |
| Nanji, AA | 1 |
| Schreiber, DH | 1 |
| Hudman, C | 1 |
| Sanders, HD | 1 |
| Ponticelli, C | 1 |
| Passerini, P | 1 |
| Como, G | 1 |
| Melis, P | 1 |
| Viganò, E | 1 |
| Pozzi, C | 1 |
| Altieri, P | 1 |
| Comerma-Coma, MI | 1 |
| Sans-Boix, A | 1 |
| Tuset-Andújar, E | 1 |
| Andreu-Navarro, J | 1 |
| Pérez-Ruiz, A | 1 |
| Naval-Marcos, I | 1 |
| Yonemura, K | 1 |
| Suzuki, T | 1 |
| Sano, K | 1 |
| Fujigaki, Y | 1 |
| Ikegaya, N | 1 |
| Hishida, A | 1 |
| Schnitzer, TJ | 1 |
| Ansell, BM | 1 |
| Hagge, W | 1 |
| Hautekeete, ML | 1 |
| Berneman, ZN | 1 |
| Bieger, R | 1 |
| Stevens, WJ | 1 |
| Bridts, C | 1 |
| Buyssens, N | 1 |
| Peetermans, ME | 1 |
2 reviews available for chlorambucil and Acute Kidney Injury
| Article | Year |
|---|---|
Primary nephrotic syndrome in the elderly.
Topics: Actuarial Analysis; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Aged; Chlorambucil; Female; | 1993 |
[Haematuria in children. III. Treatment of glomerular diseases (author's transl)].
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Glomerulonephri | 1978 |
6 other studies available for chlorambucil and Acute Kidney Injury
| Article | Year |
|---|---|
Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Aged; Chlorambucil; Drug Eruptions; Eosinophilia; Exan | 2009 |
Acute renal failure and seizures associated with chlorambucil overdose.
Topics: Acute Kidney Injury; Adult; Chlorambucil; Creatinine; Humans; Male; Seizures | 1983 |
Reversible renal failure due to specific infiltration of the kidney in chronic lymphocytic leukaemia.
Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Chlorambucil | 1998 |
A case with acute renal failure complicated by Waldenström's macroglobulinemia and cryoglobulinemia.
Topics: Acute Kidney Injury; Chlorambucil; Combined Modality Therapy; Cryoglobulinemia; Follow-Up Studies; H | 2000 |
Amyloidosis in juvenile chronic polyarthritis.
Topics: Acute Kidney Injury; Adolescent; Adult; Amyloidosis; Arthritis, Juvenile; Child; Child, Preschool; C | 1977 |
Purpura fulminans in pneumococcal sepsis.
Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Fema | 1986 |