chlorambucil has been researched along with Acquired Immunodeficiency Syndrome in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pneumocystis carinii pneumonia is today an opportunistic infection of major importance, occurring in immunosuppressed patients." | 1.27 | Pneumocystis carinii pneumonia in Johannesburg. ( Abramowitz, JA; Hurwitz, MD; Kallenbach, JM; Pincus, PS; Zwi, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pincus, PS | 1 |
| Hurwitz, MD | 1 |
| Kallenbach, JM | 1 |
| Abramowitz, JA | 1 |
| Zwi, S | 1 |
1 other study available for chlorambucil and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Pneumocystis carinii pneumonia in Johannesburg.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Chlorambucil; Female; Humans; Immunologic Def | 1987 |