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chlorambucil and ATLL

chlorambucil has been researched along with ATLL in 5 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Research Excerpts

ExcerptRelevanceReference
"Both human lymphoblastoid interferon (HLBI) and bestrabucil, the conjugate of chlorambucil and beta-estradiol, have antitumor activity against adult T-cell leukemia-lymphoma (ATLL)."5.07A combination trial of human lymphoblastoid interferon and bestrabucil (KM2210) for adult T-cell leukemia-lymphoma. ( Ezaki, K; Hirano, M; Hirota, Y; Kimura, K; Naito, K; Ohno, R; Shirakawa, S; Yamada, K, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mentz, F1
Baudet, S1
Blanc, C1
Issaly, F1
Binet, JL1
Merle-Beral, H1
Cabrera, ME1
Labra, S1
Ford, A1
Matutes, E1
Kode, J1
Advani, S1
Chiplunkar, S1
Tsurumi, H1
Tani, K1
Tsuruta, T1
Shirato, R1
Matsudaira, T1
Tojo, A1
Wada, C1
Uchida, H1
Ozawa, K1
Asano, S1
Ezaki, K1
Hirano, M1
Ohno, R1
Yamada, K1
Naito, K1
Hirota, Y1
Shirakawa, S1
Kimura, K1

Trials

1 trial available for chlorambucil and ATLL

ArticleYear
A combination trial of human lymphoblastoid interferon and bestrabucil (KM2210) for adult T-cell leukemia-lymphoma.
    Cancer, 1991, Aug-15, Volume: 68, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Estrad

1991

Other Studies

4 other studies available for chlorambucil and ATLL

ArticleYear
Simple, fast method of detection apoptosis in lymphoid cells.
    Cytometry, 1998, Jun-01, Volume: 32, Issue:2

    Topics: Apoptosis; Blood Cell Count; Cells, Cultured; Chlorambucil; Flow Cytometry; Humans; Immunohistochemi

1998
HTLV-I induced intestinal lymphoma.
    Leukemia & lymphoma, 1999, Volume: 35, Issue:5-6

    Topics: Adult; Antineoplastic Agents, Alkylating; Chile; Chlorambucil; Diarrhea; DNA, Viral; Duodenal Neopla

1999
T-cell receptor gamma and delta gene rearrangements in T-cell acute lymphoblastic leukemia in Indian patients.
    Leukemia & lymphoma, 2000, Volume: 36, Issue:3-4

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child,

2000
Adult T-cell leukemia developing during immunosuppressive treatment in a renal transplant recipient.
    American journal of hematology, 1992, Volume: 41, Issue:4

    Topics: Adult; Antineoplastic Agents; Carrier State; Chlorambucil; Estradiol; Humans; Immunosuppression Ther

1992