chloral hydrate has been researched along with Vomiting in 11 studies
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloral hydrate was safe and relatively effective, causing more satisfactory behavioral and physiological outcomes than a placebo." | 2.73 | A randomized double-blinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation. ( da Costa, LR; da Costa, PS; Lima, AR, 2007) |
| "Chloral hydrate is a sedative that has been used for magnetic resonance imaging (MRI)." | 1.42 | Chloral hydrate in pediatric magnetic resonance imaging: evaluation of a 10-year sedation experience administered by radiologists. ( Angel, GJ; Arango, A; Calvo, V; Delgado, J; Delgado, JA; Rascovsky, S; Toro, R, 2015) |
| "The study investigated patient discharge parameters and postdischarge adverse events after discharge among children who received oral conscious sedation for dental treatment." | 1.42 | Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients. ( Huang, A; Tanbonliong, T, 2015) |
| "Chloral hydrate is a safe and effective agent for sedation in children with an age and weight dependent response." | 1.33 | Chloral hydrate. An effective agent for sedation in children with age and weight dependent response. ( Al-Eissa, YA; Haidar, NA; Hijazi, OM, 2005) |
| "Chloral hydrate was used in 30 patients and IV pentobarbital in 337 patients." | 1.32 | Is administration of enteric contrast material safe before abdominal CT in children who require sedation? Experience with chloral hydrate and pentobarbital. ( Donnelly, LF; Fricke, BL; Ziegler, MA, 2003) |
| " We characterize the fasting status of patients receiving procedural sedation and analgesia in a pediatric ED and assess the relationship between fasting status and adverse events." | 1.32 | Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003) |
| "Chloral hydrate is a safe and effective agent for sedation of children with known or suspected congenital heart disease who are undergoing echocardiography in the outpatient cardiology clinic." | 1.29 | Safety and efficacy of chloral hydrate sedation in children undergoing echocardiography. ( Ingall, CG; Martin, GR; Napoli, KL, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuen, VM | 1 |
| Li, BL | 1 |
| Cheuk, DK | 1 |
| Leung, MKM | 1 |
| Hui, TWC | 1 |
| Wong, IC | 1 |
| Lam, WW | 1 |
| Choi, SW | 1 |
| Irwin, MG | 1 |
| Delgado, J | 1 |
| Toro, R | 1 |
| Rascovsky, S | 1 |
| Arango, A | 1 |
| Angel, GJ | 1 |
| Calvo, V | 1 |
| Delgado, JA | 1 |
| Huang, A | 1 |
| Tanbonliong, T | 1 |
| Ghaffar, S | 1 |
| Haverland, C | 1 |
| Ramaciotti, C | 1 |
| Scott, WA | 1 |
| Lemler, MS | 1 |
| Ziegler, MA | 1 |
| Fricke, BL | 1 |
| Donnelly, LF | 1 |
| Agrawal, D | 1 |
| Manzi, SF | 1 |
| Gupta, R | 1 |
| Krauss, B | 1 |
| Hijazi, OM | 1 |
| Haidar, NA | 1 |
| Al-Eissa, YA | 1 |
| Lu, DP | 1 |
| Lu, WI | 1 |
| da Costa, LR | 1 |
| da Costa, PS | 1 |
| Lima, AR | 1 |
| Napoli, KL | 1 |
| Ingall, CG | 1 |
| Martin, GR | 1 |
| Robbins, MB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638] | 240 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | |||
| Effect of Increasing Depth of Dexmedetomidine and Propofol Anesthesia on Upper Airway Morphology in Children With History of Obstructive Sleep Apnea[NCT01344759] | Phase 4 | 60 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
This is the count of the number of patients who needed an artificial airway. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | Number of artifical airway events (Number) |
|---|---|
| Mild OSA and Dexmedetomidine | 0 |
| Mild OSA and Propofol | 1 |
| Moderate OSA and Dexmedetomidine | 1 |
| Moderate OSA and Propofol | 1 |
| Severe OSA and Dexmedetomidine | 2 |
| Severe OSA and Propofol | 5 |
The Obstructive Index is a count of the obstructive apnea events per hour of sleep (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | Apnea events/hour of sleep (Mean) |
|---|---|
| Mild OSA and Dexmedetomidine | 4.2 |
| Mild OSA and Propofol | 3.0 |
| Moderate OSA and Dexmedetomidine | 8.0 |
| Moderate OSA and Propofol | 8.0 |
| Severe OSA and Dexmedetomidine | 16.7 |
| Severe OSA and Propofol | 17.1 |
The respiratory disturbance index is a count of respiratory disturbance events per hour of sleep. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | respir.disturbance events/hr of sleep (Mean) |
|---|---|
| Mild OSA and Dexmedetomidine | 5.1 |
| Mild OSA and Propofol | 3.2 |
| Moderate OSA and Dexmedetomidine | 8.8 |
| Moderate OSA and Propofol | 7.1 |
| Severe OSA and Dexmedetomidine | 16.6 |
| Severe OSA and Propofol | 25.2 |
The patient's oxygen saturation on room air. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | percentage of SpO2 (Mean) |
|---|---|
| Mild OSA and Dexmedetomidine | 87.2 |
| Mild OSA and Propofol | 88.0 |
| Moderate OSA and Dexmedetomidine | 86.3 |
| Moderate OSA and Propofol | 89.0 |
| Severe OSA and Dexmedetomidine | 84.0 |
| Severe OSA and Propofol | 88.0 |
The primary outcome measures will be the cross sectional area of the pharyngeal airway of the patients measured at two levels soft palate (nasopharyngeal) and base of the tongue (retroglossal). Magnetic resonance images of the airway were obtained during low (1 mcg/kg/hr) and high (3 mcg/kg/hr) doses of DEX or low (100 mcg/kg/m) and high (200 mcg/kg/m) doses of Propofol. All were administered through an intravenous (IV) catheter. (NCT01344759)
Timeframe: during MRI within first 10 minutes of scanning
| Intervention | mm^2 (Median) | |||
|---|---|---|---|---|
| Low Dose Sedative, Nasopharyngeal measurement | High Dose Sedative, Nasopharyngeal measurement | Low Dose Sedative, Retroglossal measurement | High dose sedative, Retroglossal measurement | |
| Dexmedetomidine | 178.5 | 235.4 | 120.9 | 120.5 |
| Propofol | 239.9 | 201.6 | 115.1 | 108.1 |
3 trials available for chloral hydrate and Vomiting
| Article | Year |
|---|---|
A randomised controlled trial of oral chloral hydrate vs. intranasal dexmedetomidine before computerised tomography in children.
Topics: Administration, Intranasal; Administration, Oral; Child; Child, Preschool; Chloral Hydrate; Consciou | 2017 |
A randomized double-blinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation.
Topics: Anesthesia, Dental; Blood Pressure; Child Behavior; Child, Preschool; Chloral Hydrate; Conscious Sed | 2007 |
Chloral hydrate and promethazine as premedicants for the apprehensive child.
Topics: Anesthetics, Local; Child; Child, Preschool; Chloral Hydrate; Drug Synergism; Fear; Humans; Infant; | 1967 |
8 other studies available for chloral hydrate and Vomiting
| Article | Year |
|---|---|
Chloral hydrate in pediatric magnetic resonance imaging: evaluation of a 10-year sedation experience administered by radiologists.
Topics: Age Distribution; Akathisia, Drug-Induced; Child; Chloral Hydrate; Colombia; Deep Sedation; Dose-Res | 2015 |
Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients.
Topics: Administration, Oral; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Inhalation; Child; Child | 2015 |
Sedation for pediatric echocardiography: evaluation of preprocedure fasting guidelines.
Topics: Arrhythmias, Cardiac; Child, Preschool; Chloral Hydrate; Cyanosis; Echocardiography; Fasting; Heart | 2002 |
Is administration of enteric contrast material safe before abdominal CT in children who require sedation? Experience with chloral hydrate and pentobarbital.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Chloral Hydrate; Conscious Sedation; Cont | 2003 |
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C | 2003 |
Chloral hydrate. An effective agent for sedation in children with age and weight dependent response.
Topics: Administration, Oral; Age Factors; Body Weight; Child, Preschool; Chloral Hydrate; Conscious Sedatio | 2005 |
Practical oral sedation in dentistry. Part II--Clinical application of various oral sedatives and discussion.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Anesthesia, Dental; Child; Child, | 2006 |
Safety and efficacy of chloral hydrate sedation in children undergoing echocardiography.
Topics: Adolescent; Age Factors; Ambulatory Care; Blood Pressure; Child; Child, Preschool; Chloral Hydrate; | 1996 |