chloral hydrate has been researched along with Stroke in 3 studies
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloral hydrate preconditioning significantly improved the neurological outcomes and reduced the infarction and brain edema after ischemia." | 7.81 | Chloral Hydrate Preconditioning Protects Against Ischemic Stroke via Upregulating Annexin A1. ( Feng, D; Li, XF; Liu, JH; Pei, L; Shang, Y; Wu, Y; Zhang, YF, 2015) |
| "Since an ethical issue has been raised regarding the use of the well-known anesthetic agent chloral hydrate, owing to its mutagenic and carcinogenic effects in animals, attention of neuroscientists has turned to finding out an alternative agent able to meet not only potency, safety, and analgesic efficacy, but also reduced neuroprotective effect for stroke research." | 7.80 | Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue. ( Cédrick, L; Maud, P; Michèle, B; Olivier, P; Régis, B; Thavarak, O; Vincent, B, 2014) |
| "Thiopental is an anesthetic used for controlling high intracranial pressure (ICP) caused by brain surgery, brain trauma, and severe stroke." | 7.75 | Thiopental exaggerates ischemic brain damage and neurological deficits after experimental stroke in spontaneously hypertensive rats. ( Duan, WM; Duan, YF; Liu, C; Zhao, LR; Zhao, YF, 2009) |
| "Chloral hydrate preconditioning significantly improved the neurological outcomes and reduced the infarction and brain edema after ischemia." | 3.81 | Chloral Hydrate Preconditioning Protects Against Ischemic Stroke via Upregulating Annexin A1. ( Feng, D; Li, XF; Liu, JH; Pei, L; Shang, Y; Wu, Y; Zhang, YF, 2015) |
| "Since an ethical issue has been raised regarding the use of the well-known anesthetic agent chloral hydrate, owing to its mutagenic and carcinogenic effects in animals, attention of neuroscientists has turned to finding out an alternative agent able to meet not only potency, safety, and analgesic efficacy, but also reduced neuroprotective effect for stroke research." | 3.80 | Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue. ( Cédrick, L; Maud, P; Michèle, B; Olivier, P; Régis, B; Thavarak, O; Vincent, B, 2014) |
| "Thiopental is an anesthetic used for controlling high intracranial pressure (ICP) caused by brain surgery, brain trauma, and severe stroke." | 3.75 | Thiopental exaggerates ischemic brain damage and neurological deficits after experimental stroke in spontaneously hypertensive rats. ( Duan, WM; Duan, YF; Liu, C; Zhao, LR; Zhao, YF, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maud, P | 1 |
| Thavarak, O | 1 |
| Cédrick, L | 1 |
| Michèle, B | 1 |
| Vincent, B | 1 |
| Olivier, P | 1 |
| Régis, B | 1 |
| Liu, JH | 1 |
| Feng, D | 1 |
| Zhang, YF | 1 |
| Shang, Y | 1 |
| Wu, Y | 1 |
| Li, XF | 1 |
| Pei, L | 1 |
| Duan, YF | 1 |
| Liu, C | 1 |
| Zhao, YF | 1 |
| Duan, WM | 1 |
| Zhao, LR | 1 |
3 other studies available for chloral hydrate and Stroke
| Article | Year |
|---|---|
Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Bioethical Issues; Chloral Hydrate; Disease Models, An | 2014 |
Chloral Hydrate Preconditioning Protects Against Ischemic Stroke via Upregulating Annexin A1.
Topics: Animals; Annexin A1; Brain; Brain Edema; Brain Ischemia; Chloral Hydrate; Cytokines; Disease Models, | 2015 |
Thiopental exaggerates ischemic brain damage and neurological deficits after experimental stroke in spontaneously hypertensive rats.
Topics: Anesthetics, Intravenous; Animals; Brain; Brain Ischemia; Chloral Hydrate; Disease Models, Animal; D | 2009 |