chloral hydrate has been researched along with Necrosis in 4 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " On the basis of the mild liver toxicity (histopathological and clinical) observed in males at the highest doses (168 mg/kg-day), the no observed adverse effect level (NOAEL) for oral exposure of rats to chloral hydrate for 90 days is considered to be 96 mg/kg-day (600 mg/L)." | 1.28 | Ninety-day toxicity study of chloral hydrate in the Sprague-Dawley rat. ( Daniel, FB; Olson, GR; Page, NP; Robinson, M; Stober, JA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzdal'skaia, IP | 1 |
| Ivakhniuk, IS | 1 |
| Magloczky, Z | 1 |
| Freund, TF | 1 |
| Daniel, FB | 1 |
| Robinson, M | 1 |
| Stober, JA | 1 |
| Page, NP | 1 |
| Olson, GR | 1 |
| Veller, ID | 1 |
| Richardson, JP | 1 |
| Doyle, JC | 1 |
| Keating, M | 1 |
4 other studies available for chloral hydrate and Necrosis
| Article | Year |
|---|---|
[Dependence of the rate of development of Zenker's necrosis in the fibers of the frog sartorius muscle on the concentration of chloral hydrate, urea and urethane].
Topics: Animals; Chloral Hydrate; Dose-Response Relationship, Drug; In Vitro Techniques; Muscles; Necrosis; | 1983 |
Selective neuronal death in the contralateral hippocampus following unilateral kainate injections into the CA3 subfield.
Topics: Anesthetics; Animals; Biomarkers; Calbindin 2; Cell Death; Chloral Hydrate; Disease Models, Animal; | 1993 |
Ninety-day toxicity study of chloral hydrate in the Sprague-Dawley rat.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Behavior, Animal; Blood Urea Nitrogen; B | 1992 |
Gastric necrosis: a rare complication of chloral hydrate intoxication.
Topics: Adult; Chloral Hydrate; Esophagus; Female; Humans; Necrosis; Stomach; Stomach Diseases | 1972 |