chloral hydrate has been researched along with Carcinoma, Hepatocellular in 2 studies
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloral hydrate, which is used as a sedative in pediatric medicine and is a by-product of water chlorination, is hepatocarcinogenic in B6C3F1 mice, a strain that can exhibit high rates of background liver tumor incidence, which are associated with increased body weight." | 3.72 | Dietary controlled carcinogenicity study of chloral hydrate in male B6C3F1 mice. ( Allaben, WT; Allen, LJ; Hussain, N; Latendresse, JR; Leakey, JE; Seng, JE, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leakey, JE | 2 |
| Seng, JE | 2 |
| Allaben, WT | 2 |
| Latendresse, JR | 1 |
| Hussain, N | 1 |
| Allen, LJ | 1 |
2 other studies available for chloral hydrate and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Body weight considerations in the B6C3F1 mouse and the use of dietary control to standardize background tumor incidence in chronic bioassays.
Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinogenicity Tests; Carcinoma, Hepatocellular; Chloral | 2003 |
Dietary controlled carcinogenicity study of chloral hydrate in male B6C3F1 mice.
Topics: Adenoma, Liver Cell; Administration, Oral; Animals; Body Weight; Carcinogenicity Tests; Carcinoma, H | 2003 |