chloral hydrate has been researched along with Aneuploid in 27 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In view of tissue- and sex-specific differences in chemically-induced aneuploidy, we analysed the effects of chloral hydrate (CH) on cell-cycle progression, spindle formation and aneuploidy in in vitro maturing mouse oocytes with cytogenetic and immunofluorescent methods." | 7.69 | Chloral hydrate induced spindle aberrations, metaphase I arrest and aneuploidy in mouse oocytes. ( Betzendahl, I; Eichenlaub-Ritter, U, 1995) |
| "The induction of aneuploidy in cultured Chinese hamster cells by propionaldehyde (PA) and chloral hydrate (CH) has been studied." | 7.68 | The induction of aneuploidy in cultured Chinese hamster cells by propionaldehyde and chloral hydrate. ( Dulout, FN; Furnus, CC; Terreros, MC; Ulrich, MA, 1990) |
| "Chloral hydrate (CH) has been assayed for its ability to induce chromosome number variation in human lymphocytes in culture." | 5.28 | Aneuploidy induced by chloral hydrate detected in human lymphocytes with the Y97 probe. ( De Carli, L; De Sario, A; Vagnarelli, P, 1990) |
| "Induced aneuploidy can be distinguished from chromosome breakage by the pattern of marker segregation." | 5.27 | Tests which distinguish induced crossing-over and aneuploidy from secondary segregation in Aspergillus treated with chloral hydrate or gamma-rays. ( Käfer, E, 1986) |
| "The synopsis of the in vivo test results in the first collaborative CEC Aneuploidy Project with 10 selected chemicals, colchicine (COL), econazole (EZ), chloral hydrate (CH), hydroquinone (HQ), diazepam (DZ), thiabendazole (TB), cadmium chloride (CD), thimerosal (TM), pyrimethamine (PY) and vinblastine (VBL), allowed several conclusions." | 4.78 | Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study. ( Adler, ID, 1993) |
| "In view of tissue- and sex-specific differences in chemically-induced aneuploidy, we analysed the effects of chloral hydrate (CH) on cell-cycle progression, spindle formation and aneuploidy in in vitro maturing mouse oocytes with cytogenetic and immunofluorescent methods." | 3.69 | Chloral hydrate induced spindle aberrations, metaphase I arrest and aneuploidy in mouse oocytes. ( Betzendahl, I; Eichenlaub-Ritter, U, 1995) |
| "The possibility of using a micronucleus (MN) assay in mouse germ cells for the identification of aneuploidogenic agents was evaluated by comparing the pattern of effects induced by 4 chemicals with different mechanisms of action (adriamycin, ADM; mitomycin C, MMC; chloral hydrate, CH; ethylenedinitrilotetraacetic acid, EDTA)." | 3.68 | Detection of aneuploidy in male germ cells of mice by means of a meiotic micronucleus assay. ( Levis, AG; Russo, A, 1992) |
| "We tested the 10 known or suspected spindle poisons (colchicine, econazole nitrate, chloral hydrate, hydroquinone, diazepam, thiabendazole, cadmium chloride, thimerosal, pyrimethamine and vinblastine) of the coordinated EEC programme for induction of aneuploidy with the in vitro porcine brain tubulin assembly assay." | 3.68 | Effects of 10 known or suspected spindle poisons in the in vitro porcine brain tubulin assembly assay. ( Albertini, S; Brunner, M; Würgler, FE, 1991) |
| "The induction of aneuploidy in cultured Chinese hamster cells by propionaldehyde (PA) and chloral hydrate (CH) has been studied." | 3.68 | The induction of aneuploidy in cultured Chinese hamster cells by propionaldehyde and chloral hydrate. ( Dulout, FN; Furnus, CC; Terreros, MC; Ulrich, MA, 1990) |
| "EMS and methotrexate modestly induced aneuploidy, while chloral hydrate and MMS failed to illicit any significant induction." | 1.31 | Simultaneous measurement of the frequencies of intrachromosomal recombination and chromosome gain using the yeast DEL assay. ( Howlett, NG; Schiestl, RH, 2000) |
| "Pyrimethamine did not inhibit the assembly of microtubules, but produced aberrant forms." | 1.29 | Effects of potential aneuploidy inducing agents on microtubule assembly in vitro. ( Hartley-Asp, B; Wallin, M, 1993) |
| "The test chemicals included in the EC Aneuploidy Project were evaluated for their ability to induce aneuploidy or aneuploidy related endpoints in assays using in vitro tubulin polymerisation, fungi and wheat." | 1.29 | An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens. ( Parry, JM, 1993) |
| "Cadmium chloride was negative in the chromosome enumeration assay and hydroquinone yielded inconclusive results." | 1.29 | A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens. ( Parry, EM; Parry, JM; Warr, TJ, 1993) |
| "Mitomycin-C (MMC) was used as a positive control for the induction of micronuclei." | 1.29 | The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens. ( Lynch, AM; Parry, JM, 1993) |
| "An analysis of chromosomal aberrations was carried out in bone marrow cells of mice with the first five chemicals: colchicine (COL), econazole (EZ), chloralhydrate (CH), hydroquinone (HQ) and diazepam (DIAZ)." | 1.28 | Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells. ( Adler, ID; Xu, W, 1990) |
| "Colchicine was the only compound tested that resulted in a statistically significant (P less than 0." | 1.27 | Analysis of mouse metaphase II oocytes as an assay for chemically induced aneuploidy. ( Mailhes, JB; Payne, HS; Preston, RJ; Yuan, ZP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (18.52) | 18.7374 |
| 1990's | 21 (77.78) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferguson, LR | 1 |
| Morcombe, P | 1 |
| Triggs, CN | 1 |
| Natarajan, AT | 2 |
| Leopardi, P | 1 |
| Zijno, A | 1 |
| Bassani, B | 1 |
| Pacchierotti, F | 1 |
| Adler, ID | 2 |
| Wallin, M | 1 |
| Hartley-Asp, B | 1 |
| Parry, JM | 4 |
| Warr, TJ | 1 |
| Parry, EM | 1 |
| Sors, A | 1 |
| Duivenvoorden, WC | 1 |
| Meijers, M | 1 |
| Zwanenburg, TS | 1 |
| Lynch, AM | 1 |
| Gibson, DP | 1 |
| Aardema, MJ | 2 |
| Kerckaert, GA | 1 |
| Carr, GJ | 1 |
| Brauninger, RM | 1 |
| LeBoeuf, RA | 1 |
| Mailhes, JB | 2 |
| Marchetti, F | 1 |
| Eichenlaub-Ritter, U | 2 |
| Betzendahl, I | 2 |
| Baart, E | 1 |
| Yin, H | 1 |
| Howlett, NG | 1 |
| Schiestl, RH | 1 |
| Russo, A | 1 |
| Levis, AG | 1 |
| Antoccia, A | 1 |
| Degrassi, F | 2 |
| Battistoni, A | 1 |
| Ciliutti, P | 1 |
| Tanzarella, C | 2 |
| Brunner, M | 1 |
| Albertini, S | 1 |
| Würgler, FE | 1 |
| Crebelli, R | 1 |
| Conti, G | 1 |
| Conti, L | 1 |
| Carere, A | 1 |
| Vagnarelli, P | 1 |
| De Sario, A | 1 |
| De Carli, L | 1 |
| Furnus, CC | 1 |
| Ulrich, MA | 1 |
| Terreros, MC | 1 |
| Dulout, FN | 1 |
| Xu, W | 1 |
| Kappas, A | 1 |
| Käfer, E | 2 |
| Preston, RJ | 1 |
| Yuan, ZP | 1 |
| Payne, HS | 1 |
2 reviews available for chloral hydrate and Aneuploid
| Article | Year |
|---|---|
Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromos | 1993 |
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
Topics: Aneuploidy; Animals; Aspergillus; Cadmium; Cadmium Chloride; Cell Cycle; Cells, Cultured; Chloral Hy | 1993 |
25 other studies available for chloral hydrate and Aneuploid
| Article | Year |
|---|---|
The size of cytokinesis-blocked micronuclei in human peripheral blood lymphocytes as a measure of aneuploidy induction by Set A compounds in the EEC trial.
Topics: Aneuploidy; Cell Division; Cells, Cultured; Chloral Hydrate; Colchicine; Cytoplasm; Diazepam; Dose-R | 1993 |
An overview of the results of testing of known or suspected aneugens using mammalian cells in vitro.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Cells, Cultured; Chloral H | 1993 |
In vivo studies on chemically induced aneuploidy in mouse somatic and germinal cells.
Topics: Aneuploidy; Animals; Bone Marrow; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Colchicine; | 1993 |
Effects of potential aneuploidy inducing agents on microtubule assembly in vitro.
Topics: Aneuploidy; Animals; Brain; Cadmium; Cadmium Chloride; Cattle; Chloral Hydrate; Chlorides; Colchicin | 1993 |
An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens.
Topics: Aneuploidy; Animals; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Co | 1993 |
A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat | 1993 |
Induction of mitotic aneuploidy using Chinese hamster primary embryonic cells. Test results of 10 chemicals.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Colchic | 1993 |
The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat | 1993 |
Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo (SHE) cell transformation assay.
Topics: Aneuploidy; Animals; Asbestos; Benomyl; Cadmium; Cadmium Chloride; Carcinogenicity Tests; Carcinogen | 1995 |
Investigation of aneuploidy induction in mouse oocytes following exposure to vinblastine-sulfate, pyrimethamine, diethylstilbestrol diphosphate, or chloral hydrate.
Topics: Aneuploidy; Animals; Chloral Hydrate; Diethylstilbestrol; Dose-Response Relationship, Drug; Female; | 1993 |
Chloral hydrate induced spindle aberrations, metaphase I arrest and aneuploidy in mouse oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Aneuploidy; Animals; Cell Cycle; Cells, Cultured; Chloral Hydrate; Chro | 1995 |
Mechanisms of spontaneous and chemically-induced aneuploidy in mammalian oogenesis: basis of sex-specific differences in response to aneugens and the necessity for further tests.
Topics: Age Factors; Aneuploidy; Animals; Chloral Hydrate; Diazepam; Female; Meiosis; Metaphase; Mice; Mitoc | 1996 |
Simultaneous measurement of the frequencies of intrachromosomal recombination and chromosome gain using the yeast DEL assay.
Topics: Aneuploidy; Benomyl; Chloral Hydrate; Chromosomes, Fungal; Dactinomycin; Ethyl Methanesulfonate; Flo | 2000 |
Detection of aneuploidy in male germ cells of mice by means of a meiotic micronucleus assay.
Topics: Aneuploidy; Animals; Chloral Hydrate; Doxorubicin; Edetic Acid; Male; Meiosis; Mice; Mice, Inbred BA | 1992 |
In vitro micronucleus test with kinetochore staining: evaluation of test performance.
Topics: Aneuploidy; Antibodies, Monoclonal; Cadmium; Cadmium Chloride; Cell Line; Chloral Hydrate; Chromosom | 1991 |
Effects of 10 known or suspected spindle poisons in the in vitro porcine brain tubulin assembly assay.
Topics: Aneuploidy; Animals; Brain; Chloral Hydrate; Colchicine; Diazepam; Hydroquinones; Microtubules; Muta | 1991 |
In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans.
Topics: Aneuploidy; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chromosomes, Fungal; C | 1991 |
Aneuploidy induced by chloral hydrate detected in human lymphocytes with the Y97 probe.
Topics: Aneuploidy; Cell Survival; Cells, Cultured; Chloral Hydrate; DNA Probes; Humans; Lymphocyte Activati | 1990 |
The induction of aneuploidy in cultured Chinese hamster cells by propionaldehyde and chloral hydrate.
Topics: Aldehydes; Aneuploidy; Animals; Cell Line; Chloral Hydrate; Chromosome Aberrations; Cricetinae | 1990 |
Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells.
Topics: Aneuploidy; Animals; Bone Marrow; Bone Marrow Cells; Chloral Hydrate; Chromosome Aberrations; Colchi | 1990 |
On the mechanisms of induced aneuploidy in Aspergillus nidulans and validation of tests for genomic mutations.
Topics: Aneuploidy; Animals; Aspergillus nidulans; Benomyl; Chloral Hydrate; Colchicine; Econazole; Hydroqui | 1989 |
Immunofluorescent staining of kinetochores in micronuclei: a new assay for the detection of aneuploidy.
Topics: Aneuploidy; Animals; Autoantibodies; Cell Line; Cell Nucleus; Chloral Hydrate; Chromosome Aberration | 1988 |
MMS-induced primary aneuploidy and other genotoxic effects in mitotic cells of Aspergillus.
Topics: Aneuploidy; Aspergillus; Chloral Hydrate; Chromosome Aberrations; Crossing Over, Genetic; Diploidy; | 1988 |
Analysis of mouse metaphase II oocytes as an assay for chemically induced aneuploidy.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Chloral Hydrate; Colchicine; Diethylstilbestrol; Fem | 1988 |
Tests which distinguish induced crossing-over and aneuploidy from secondary segregation in Aspergillus treated with chloral hydrate or gamma-rays.
Topics: Alleles; Aneuploidy; Aspergillus nidulans; Chloral Hydrate; Crossing Over, Genetic; Gamma Rays; Muta | 1986 |