chloral hydrate has been researched along with Acidosis, Lactic in 2 studies
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloral hydrate was introduced into therapeutics more than 100 years ago, and since then a number of kinetic and metabolic studies have been conducted on this drug." | 2.68 | Kinetics and metabolism of chloral hydrate in children: identification of dichloroacetate as a metabolite. ( Davydova, N; Henderson, GN; James, MO; Stacpoole, PW; Yan, Z, 1997) |
| "Chloral hydrate (CH) is a widely used sedative." | 1.30 | Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry. ( Henderson, GN; James, MO; Stacpoole, PW; Yan, Z, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henderson, GN | 2 |
| Yan, Z | 2 |
| James, MO | 2 |
| Davydova, N | 1 |
| Stacpoole, PW | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for chloral hydrate and Acidosis, Lactic
| Article | Year |
|---|---|
Kinetics and metabolism of chloral hydrate in children: identification of dichloroacetate as a metabolite.
Topics: Acidosis, Lactic; Adolescent; Biotransformation; Child; Child, Preschool; Chloral Hydrate; Dichloroa | 1997 |
1 other study available for chloral hydrate and Acidosis, Lactic
| Article | Year |
|---|---|
Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry.
Topics: Acetals; Acetates; Acidosis, Lactic; Administration, Oral; Child; Chloral Hydrate; Dichloroacetic Ac | 1999 |