chitosan has been researched along with Spinal Cord Injuries in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (7.35) | 29.6817 |
| 2010's | 38 (55.88) | 24.3611 |
| 2020's | 25 (36.76) | 2.80 |
| Authors | Studies |
|---|---|
| Asghari, A; Gholami, M; Gilanpour, H; Sadeghinezhad, J | 1 |
| Bao, Z; Fan, D; Gao, H; Li, Z; Tian, S; Zhang, H; Zhang, W; Zhu, L | 1 |
| Bačová, M; Bimbová, K; Gálik, J; Karasová, M; Kisucká, A; Lukačová, N; Medvecky, L; Stropkovská, A; Šulla, I | 1 |
| Duan, H; Fan, Y; Gao, Y; Hao, P; Li, X; Rao, JS; Shang, J; Sun, YE; Yang, Z; Zhao, C; Zhao, W | 1 |
| An, J; Li, Y; Mei, X; Tian, H; Tong, L; Wu, C; Wu, Q; Zou, Z | 1 |
| Hu, T; Jiang, GB; Li, S; Li, WX; Liu, J; Qi, J; Xiong, M; Zhang, H; Zhou, X | 1 |
| Dai, H; Dong, X; Liu, K; Wang, Y; Wu, X | 1 |
| Duan, H; Gao, Y; Gu, Y; Hao, F; Hao, P; Li, X; Song, J; Wang, Z; Yang, Z; Zhao, W | 1 |
| Ashraf, SS; Frounchi, M; Heydari, Y; Kheirabadi, MZ; Kiani, S; Mashayekhan, S; Sabourian, P | 1 |
| Cao, H; Jiang, T; Jin, L; Luo, Y; Tao, F; Tao, H; Xiang, W | 1 |
| Arabzadeh, E; Ramirez-Campillo, R; Zargani, M | 1 |
| Feng, X; Hu, JL; Liu, JP; Luo, HL; Xu, YS; Zhang, WJ; Zuo, C | 1 |
| Bashakhanov, RM; Botasheva, VS; Grin, AA; Kovalev, DA; Lebenstein-Gumovski, MV; Shatohkin, AA; Zhirov, AM | 1 |
| Chen, C; Duan, JH; Li, XH; Liang, J; Liu, XY; Ming, D; Sun, XZ; Tu, Y; Wang, JJ; Wang, KQ; Wang, Y; Wei, MG; Zhang, S; Zhao, CY; Zhong, L | 1 |
| Bonferoni, MC; Collina, S; Fagiani, F; Ferrari, F; Lanni, C; Rossi, S; Rui, M; Sandri, G; Vigani, B | 1 |
| Ham, TR; Hamrangsekachaee, M; Leipzig, ND; Pukale, DD | 2 |
| Chen, Y; Cheng, T; Gao, F; Guan, F; Yao, M; Zhang, J | 1 |
| Liu, Z; Wang, D; Wang, K; Wang, Z; Wu, H | 2 |
| Han, GH; Han, IB; Kim, SJ; Ko, WK; Lee, D; Lee, JS; Nah, H; Sohn, S | 1 |
| Ghorbani, R; Hashemnia, M; Javdani, M | 1 |
| Delaney, KH; Kwiecien, JM; Lucas, AR; Yaron, JR | 1 |
| Feng, X; Gao, J; Gu, J; Shao, H; Song, X; Wu, J; Xu, Y | 1 |
| Gwak, SJ; Ha, Y; Jeong, HJ; Lee, SJ; Yun, Y | 1 |
| Basak, AT; Bozkurt, G; Cakici, N; Cetinkaya, DU; Denkbas, EB; Korkusuz, P; Purali, N | 1 |
| Dai, Y; Ding, E; Ding, J; Huang, C; Le, L; Liu, Y; Wang, L; Yang, J | 1 |
| Decherchi, P; Marqueste, T; Modrzejewska, Z; Nawrotek, K; Rusak, A; Zarzycki, R | 1 |
| Gao, W; Li, J | 1 |
| Benassy, MN; Chedly, J; David, L; Montembault, A; Mouffle, C; Nothias, F; Soares, S; Taxi, J; Veron-Ravaille, M; von Boxberg, Y | 1 |
| Chen, XG; Hua, F; Tang, HH; Wang, SG | 1 |
| Duan, H; Fan, KS; Hao, P; He, Q; Li, X; Liu, Z; Rao, JS; Shang, J; Song, W; Sun, YE; Tian, Z; Wei, RH; Yang, Z; Yu, J; Zhang, A; Zhao, C; Zhao, W | 1 |
| Farrag, M; Grimm, RK; Leipzig, ND; Mohrman, AE | 1 |
| Dalton Dietrich, W | 1 |
| Cheng, L; Duan, H; Haggerty, AE; Hao, P; Lemmon, VP; Li, X; Liebl, DJ; Oudega, M; Shang, J; Shi, Y; Sun, J; Sun, YE; Wang, Z | 1 |
| Fang, X; Song, H | 1 |
| Boido, M; Favaro, E; Fusaro, R; Gentile, P; Ghibaudi, M; Tonda-Turo, C | 1 |
| Aili, D; Chen, Q; Hu, X; Jin, Q; Li, Y; Qian, H; Tang, W; Zhou, X | 1 |
| Shea, LD; Thomas, AM | 1 |
| Abdel-Aziz, MT; Abdel-Fattah, DS; Amr, SM; Atta, HM; Galal, AA; Gouda, A; Koptan, WT; Rashed, LA | 1 |
| Cheng, JX; Lee, SY; Ouyang, Z; Park, K; Tyler, JY; Wang, H; Wu, W; Wu, X; Xu, XM | 1 |
| Choi, BH; Kim, M; Park, SR | 1 |
| Donius, AE; Francis, NL; Hunger, PM; Wegst, UG; Wheatley, MA | 1 |
| Fangling, X; Huasong, G; Jian, R; Jianhong, S; Lei, Z; Qingfeng, H; Sheyu, L; Xiaojian, L; Xing, S; Yan, Z; Yaohua, Y; Yilu, G; Yixu, Y | 1 |
| Gwak, SJ; Ha, Y; Kim, K; Koo, H; Lee, HY; Yhee, JY; Yoon, DH; Yun, Y | 1 |
| Almazan, G; Mekhail, M; Tabrizian, M | 1 |
| Huang, S; Li, X; Ni, S; Qi, H; Wang, J; Xia, T; Zhu, X | 1 |
| Duan, H; Hao, P; Li, X; Sun, YE; Yang, Z; Ye, K; Zhang, A; Zhang, S | 1 |
| Chen, Z; Cheng, L; Cheng, Y; Duan, H; Fan, KS; Ge, W; Horvath, S; Li, X; Luo, D; Sofroniew, MV; Sun, YE; Xi, Y; Yang, Z; Zhang, A | 1 |
| De Filippis, L; Pang, ZP; Südhof, TC | 1 |
| Kingham, PJ; Kjems, J; Kolar, MK; Louw, AM; Novikov, LN; Novikova, LN; Wiberg, M | 1 |
| Bao, G; Chen, J; Cui, Z; Feng, G; Feng, X; Gu, Z; Lu, X; Lu, Y; Sun, Y; Xu, G; Xu, L; Zhang, J | 1 |
| Ha, KY; Kim, JW; Kim, YC; Kim, YH | 1 |
| Bin, S; Pan, F; Pan, J; Wu, XF; Zhou, N; Zhou, ZH | 1 |
| Guo, XD; Kim, H; Morshead, C; Nomura, H; Shoichet, M; Tator, C; Zahir, T | 1 |
| Baladie, B; Katayama, Y; Morshead, CM; Nomura, H; Shoichet, MS; Tator, CH | 1 |
| Chen, W; Li, X; Wang, T; Yang, Z; Zhang, A | 1 |
| Ban, DX; Chang, J; Feng, SQ; Kong, XH; Liu, Y; Wang, CY; Wang, HJ; Zhang, DP | 1 |
| Lan, X; Li, H; Wang, D; Wen, Y | 1 |
| Borgens, RB; Cho, Y; Shi, R | 1 |
| Kim, H; Kulbatski, I; Morshead, CM; Mothe, A; Nomura, H; Shoichet, MS; Tator, CH; Zahir, T | 1 |
| Beskonakli, E; Bodur, E; Eroglu, H; Nacar, O; Nemutlu, E; Oner, L; Sargon, MF; Turkoglu, OF | 1 |
| Bozkurt, G; Kim, H; Mothe, AJ; Shoichet, MS; Tator, CH; Zahir, T | 1 |
| An, SS; Gwak, SJ; Ha, Y; Jung, JK; Kim, HJ; Kim, KN; Kong, MH; Lee, HY; Oh, JS; Pennant, WA; Yoon, DH | 1 |
| Chen, X; Chen, Y; Gao, Y; Gu, X; Li, Y; Lin, W; Wang, X; Yang, Y; Yao, J | 1 |
| Guo, X; Katayama, Y; Morshead, CM; Mothe, A; Shoichet, MS; Tator, CH; Zahir, T | 1 |
| Kazazian, K; Shoichet, MS; Yu, LM | 1 |
| Katayama, Y; Kim, H; Kulbatski, I; Morshead, CM; Nomura, H; Shoichet, MS; Tator, CH; Zahir, T | 1 |
4 review(s) available for chitosan and Spinal Cord Injuries
| Article | Year |
|---|---|
Applications of chitosan-based biomaterials: From preparation to spinal cord injury neuroprosthetic treatment.
Topics: Biocompatible Materials; Chitosan; Humans; Spinal Cord Injuries; Spinal Cord Regeneration; Tissue Scaffolds | 2023 |
Biomaterials and strategies for repairing spinal cord lesions.
Topics: Animals; Astrocytes; Axons; Biocompatible Materials; Chitosan; Collagen; Gliosis; Humans; Hyaluronic Acid; Nanostructures; Nerve Regeneration; Spinal Cord Injuries | 2021 |
Application of stem cells and chitosan in the repair of spinal cord injury.
Topics: Animals; Chitosan; Humans; Nerve Growth Factors; Neural Stem Cells; Recovery of Function; Spinal Cord Injuries; Stem Cell Transplantation; Tissue Scaffolds | 2019 |
Biomaterial scaffolds used for the regeneration of spinal cord injury (SCI).
Topics: Alginates; Animals; Apoptosis; Axons; Biocompatible Materials; Chitosan; Collagen; Disease Models, Animal; Drug Delivery Systems; Fibrin; Humans; Hyaluronic Acid; Inflammation; Lactic Acid; Materials Testing; Peptides; Polyesters; Polymers; Sepharose; Spinal Cord; Spinal Cord Injuries; Spinal Cord Regeneration; Stem Cells; Tissue Engineering; Tissue Scaffolds | 2014 |
64 other study(ies) available for chitosan and Spinal Cord Injuries
| Article | Year |
|---|---|
Facile fabrication of an erythropoietin-alginate/chitosan hydrogel and evaluation of its local therapeutic effects on spinal cord injury in rats.
Topics: Alginates; Animals; bcl-2-Associated X Protein; Cell Line; Cell Survival; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Erythropoietin; Gene Expression Regulation; Humans; Hydrogels; Male; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2021 |
Preparation of Drug Sustained-Release Scaffold with De-Epithelized Human Amniotic Epithelial Cells and Thiolated Chitosan Nanocarriers and Its Repair Effect on Spinal Cord Injury.
Topics: Animals; Chitosan; Delayed-Action Preparations; Epithelial Cells; Humans; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tissue Scaffolds | 2022 |
Combined therapy (Rho-A-kinase inhibitor and chitosan/collagen porous scaffold) provides a supportive environment for endogenous regenerative processes after spinal cord trauma.
Topics: Animals; Chitosan; Collagen; Nerve Regeneration; Porosity; Rats; Spinal Cord; Spinal Cord Injuries | 2022 |
Chronic spinal cord injury repair by NT3-chitosan only occurs after clearance of the lesion scar.
Topics: Animals; Chitosan; Cicatrix; Diffusion Tensor Imaging; Nerve Regeneration; Rats; Spinal Cord Injuries | 2022 |
Chitosan-modified hollow manganese dioxide nanoparticles loaded with resveratrol for the treatment of spinal cord injury.
Topics: Animals; Apoptosis; Caspase 3; Chitosan; Manganese Compounds; Nanoparticles; Oxidative Stress; Oxides; Rats; Rats, Sprague-Dawley; Resveratrol; Spinal Cord Injuries | 2022 |
Cannabidiol-loaded injectable chitosan-based hydrogels promote spinal cord injury repair by enhancing mitochondrial biogenesis.
Topics: Animals; Cannabidiol; Chitosan; Hydrogels; Organelle Biogenesis; Rats; Spinal Cord Injuries | 2022 |
Dopamine-modified chitosan hydrogel for spinal cord injury.
Topics: Animals; Antioxidants; Chitosan; Citric Acid; Dopamine; Hydrogels; Rats; Spinal Cord; Spinal Cord Injuries | 2022 |
Circuit reconstruction of newborn neurons after spinal cord injury in adult rats via an NT3-chitosan scaffold.
Topics: Animals; Chitosan; Motor Neurons; Nerve Regeneration; Paraplegia; Pyramidal Tracts; Rats; Spinal Cord; Spinal Cord Injuries | 2023 |
Targeting reactive astrocytes by pH-responsive ligand-bonded polymeric nanoparticles in spinal cord injury.
Topics: Animals; Astrocytes; Chitosan; Hydrogen-Ion Concentration; Ligands; Lipopolysaccharides; Nanoparticles; Rats; Spinal Cord Injuries | 2023 |
Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats.
Topics: Animals; Antioxidants; Arginine; Atrophy; Autophagy; Brain-Derived Neurotrophic Factor; Chitosan; gamma-Aminobutyric Acid; Microtubule-Associated Proteins; Motor Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Swimming | 2023 |
Chitosan biomaterial enhances the effect of OECs on the inhibition of sciatic nerve injury-induced neuropathic pain.
Topics: Analgesics; Animals; Biocompatible Materials; Chitosan; Nerve Regeneration; Neuralgia; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatic Neuropathy; Spinal Cord Injuries | 2023 |
[Recovery of spinal cord functions after experimental complete crossection under the effect of chitosan polymeric compounds].
Topics: Animals; Chitosan; Polyethylene Glycols; Rabbits; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2023 |
Diffusion tensor imaging predicting neurological repair of spinal cord injury with transplanting collagen/chitosan scaffold binding bFGF.
Topics: Animals; Blood Vessel Prosthesis; Chitosan; Collagen; Diffusion Tensor Imaging; Fibroblast Growth Factor 2; Rats; Spinal Cord Injuries | 2019 |
Dual-Functioning Scaffolds for the Treatment of Spinal Cord Injury: Alginate Nanofibers Loaded with the Sigma 1 Receptor (S1R) Agonist RC-33 in Chitosan Films.
Topics: Alginates; Biphenyl Compounds; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Humans; Molecular Weight; Nanofibers; Neuroblastoma; Neuroprotective Agents; Piperidines; Polyethylene Glycols; Receptors, sigma; Sigma-1 Receptor; Spinal Cord Injuries | 2019 |
Subcutaneous priming of protein-functionalized chitosan scaffolds improves function following spinal cord injury.
Topics: Animals; Chitosan; Gait; Hydrogels; Neural Stem Cells; Spinal Cord Injuries; Tissue Engineering; Tissue Scaffolds | 2020 |
A chitosan-based thermosensitive scaffold loaded with bone marrow-derived mesenchymal stem cells promotes motor function recovery in spinal cord injured mice.
Topics: Animals; Apoptosis; Biocompatible Materials; Body Temperature; Bone Marrow Cells; Cellulose; Chitosan; Culture Media; Hydrogels; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Motor Skills; Nerve Growth Factors; Neurons; Pressure; Rheology; Spinal Cord Injuries; Tissue Engineering | 2020 |
Subcutaneous priming of protein-functionalized chitosan scaffolds improves function following spinal cord injury.
Topics: Acrylamides; Animals; Antigens, Nuclear; Chitosan; Female; Intermediate Filaments; Nerve Tissue Proteins; Nestin; Neural Stem Cells; Peptides; Rats, Inbred F344; Recovery of Function; Spinal Cord Injuries; Subcutaneous Tissue; Tissue Scaffolds | 2020 |
Valproic acid-labeled chitosan nanoparticles promote recovery of neuronal injury after spinal cord injury.
Topics: Animals; Chitosan; Male; Nanoparticles; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Valproic Acid | 2020 |
Injectable Hydrogel Containing Tauroursodeoxycholic Acid for Anti-neuroinflammatory Therapy After Spinal Cord Injury in Rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Behavior, Animal; Chitosan; Cytokines; Glial Fibrillary Acidic Protein; Hyaluronic Acid; Hydrogels; Inflammation Mediators; Injections; MAP Kinase Signaling System; Motor Activity; Neuraminidase; Phosphorylation; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Taurochenodeoxycholic Acid; Tumor Necrosis Factor-alpha | 2020 |
Histopathological Evaluation of Spinal Cord with Experimental Traumatic Injury Following Implantation of a Controlled Released Drug Delivery System of Chitosan Hydrogel Loaded with Selenium Nanoparticle.
Topics: Animals; Chitosan; Drug Delivery Systems; Female; Hydrogels; Nanoparticles; Rats; Rats, Sprague-Dawley; Selenium; Spinal Cord; Spinal Cord Injuries | 2021 |
Neurologic and Histologic Tests Used to Measure Neuroprotective Effectiveness of Virus-Derived Immune-Modulating Proteins.
Topics: Animals; Anti-Inflammatory Agents; Chitosan; Disease Models, Animal; Drug Delivery Systems; Hydrogels; Immunologic Factors; Injections, Epidural; Macrophages; Male; Motor Activity; Myxoma virus; Neuroprotective Agents; Rats; Rats, Long-Evans; Receptors, Interferon; Spinal Cord; Spinal Cord Injuries; Viral Proteins | 2021 |
Valproic Acid Labeled Chitosan Nanoparticles Promote the Proliferation and Differentiation of Neural Stem Cells After Spinal Cord Injury.
Topics: Animals; Cell Differentiation; Cell Proliferation; Chitosan; Locomotion; Male; Nanoparticles; Neural Stem Cells; Rats, Sprague-Dawley; Spinal Cord Injuries; Valproic Acid | 2021 |
A sandwich structured drug delivery composite membrane for improved recovery after spinal cord injury under longtime controlled release.
Topics: Chitosan; Delayed-Action Preparations; Humans; Mesenchymal Stem Cells; Microspheres; Spinal Cord; Spinal Cord Injuries | 2021 |
Chitosan Channels Stuffed with Mesenchyme Originated Stem/Progenitor Cells for Renovate Axonal Regeneration in Complete Spinal Cord Transection.
Topics: Animals; Axons; Biocompatible Materials; Chitosan; Female; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mesoderm; Nerve Regeneration; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries | 2021 |
Thermosensitive quaternized chitosan hydrogel scaffolds promote neural differentiation in bone marrow mesenchymal stem cells and functional recovery in a rat spinal cord injury model.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Chitosan; Hydrogels; Male; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Transfection | 2021 |
Thermogelling chitosan lactate hydrogel improves functional recovery after a C2 spinal cord hemisection in rat.
Topics: Animals; Cell Line; Chitosan; Hydrogels; Lactic Acid; Male; Mice; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2017 |
Targeted siRNA delivery reduces nitric oxide mediated cell death after spinal cord injury.
Topics: Animals; Apoptosis; Cells, Cultured; Chitosan; Female; Macrophages; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Small Interfering; RNAi Therapeutics; Spinal Cord Injuries; Transfection | 2017 |
Physical chitosan microhydrogels as scaffolds for spinal cord injury restoration and axon regeneration.
Topics: Animals; Axons; Biocompatible Materials; Chitosan; Cicatrix; Female; Hydrogel, Polyethylene Glycol Dimethacrylate; Locomotion; Myelin Sheath; Nerve Regeneration; Rats; Rats, Wistar; Recovery of Function; Schwann Cells; Spinal Cord Injuries; Tissue Scaffolds; Water | 2017 |
Albumin-Conjugated Lipid-Based Multilayered Nanoemulsion Improves Drug Specificity and Anti-Inflammatory Potential at the Spinal Cord Injury gSite after Intravenous Administration.
Topics: Administration, Intravenous; Albumins; Animals; Anti-Inflammatory Agents; Apoptosis; Astrocytes; Cell Survival; Chitosan; Drug Liberation; Emulsions; Female; Lipids; Methylprednisolone; Nanostructures; Particle Size; Rats; Spinal Cord Injuries | 2018 |
NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury.
Topics: Animals; Axons; Chitosan; Diffusion Tensor Imaging; Female; Haplorhini; Motor Neurons; Nerve Regeneration; Neurotrophin 3; Pyramidal Tracts; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2018 |
Evaluation of in situ gelling chitosan-PEG copolymer for use in the spinal cord.
Topics: Animals; Biocompatible Materials; Cells, Cultured; Chitosan; Elastic Modulus; Humans; Hydrogels; Injections; Male; Materials Testing; Polyethylene Glycols; Rats; Rats, Wistar; Spinal Cord Injuries | 2018 |
Clinical significance and potential translation of neural regeneration and functional recovery in monkeys after spinal cord injury.
Topics: Animals; Chitosan; Haplorhini; Nerve Regeneration; Recovery of Function; Spinal Cord Injuries | 2018 |
Validation study of neurotrophin-3-releasing chitosan facilitation of neural tissue generation in the severely injured adult rat spinal cord.
Topics: Animals; Chitosan; Drug Implants; Female; Nerve Regeneration; Neurotrophin 3; Random Allocation; Rats; Rats, Wistar; Severity of Illness Index; Spinal Cord; Spinal Cord Injuries | 2019 |
Synthesis of cerium oxide nanoparticles loaded on chitosan for enhanced auto-catalytic regenerative ability and biocompatibility for the spinal cord injury repair.
Topics: Biocompatible Materials; Catalysis; Cerium; Chitosan; Metal Nanoparticles; Regenerative Medicine; Spinal Cord Injuries | 2019 |
Chitosan-based hydrogel to support the paracrine activity of mesenchymal stem cells in spinal cord injury treatment.
Topics: Animals; Cell Death; Cell Line; Cell Proliferation; Cell Survival; Cells, Immobilized; Chitosan; Elastic Modulus; Glycerophosphates; Humans; Hydrogels; Hydrogen-Ion Concentration; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred C57BL; Paracrine Communication; Rheology; Spectroscopy, Fourier Transform Infrared; Spinal Cord Injuries; Temperature; Time Factors; Water | 2019 |
Polysaccharide-modified scaffolds for controlled lentivirus delivery in vitro and after spinal cord injury.
Topics: Animals; Chitosan; Female; Gene Transfer Techniques; Genetic Therapy; HEK293 Cells; Heparin; Humans; Hyaluronic Acid; Lactic Acid; Lentivirus; Luciferases; Mice; Mice, Inbred C57BL; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spinal Cord Injuries; Tissue Scaffolds | 2013 |
Bridging defects in chronic spinal cord injury using peripheral nerve grafts combined with a chitosan-laminin scaffold and enhancing regeneration through them by co-transplantation with bone-marrow-derived mesenchymal stem cells: case series of 14 patient
Topics: Adolescent; Adult; Bone Marrow Cells; Cell Transplantation; Child; Chitosan; Female; Follow-Up Studies; Humans; Laminin; Male; Mesenchymal Stem Cells; Middle Aged; Nerve Regeneration; Peripheral Nerves; Recovery of Function; Spinal Cord Injuries; Young Adult | 2014 |
Neuroprotective ferulic acid (FA)-glycol chitosan (GC) nanoparticles for functional restoration of traumatically injured spinal cord.
Topics: Animals; Biological Availability; Cells, Cultured; Chitosan; Coumaric Acids; Locomotion; Male; Nanoparticles; Neuroprotective Agents; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Spinal Cord Injuries | 2014 |
Strategies for neurotrophin-3 and chondroitinase ABC release from freeze-cast chitosan-alginate nerve-guidance scaffolds.
Topics: Alginates; Animals; Axons; Chitosan; Chondroitin ABC Lyase; Drug Compounding; Glucuronic Acid; Hexuronic Acids; Neuroglia; Neurons; Neurotrophin 3; Polymers; Spinal Cord Injuries; Tissue Engineering; Tissue Scaffolds | 2017 |
Repair of spinal cord injury by chitosan scaffold with glioma ECM and SB216763 implantation in adult rats.
Topics: Animals; Cell Line, Tumor; Chitosan; Glioma; Indoles; Maleimides; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tissue Scaffolds | 2015 |
Multifunctional nanoparticles for gene delivery and spinal cord injury.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; beta-Galactosidase; Chitosan; Gene Transfer Techniques; Luciferases; Male; Methylprednisolone; Mice; Nanoparticles; Neural Stem Cells; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Spinal Cord Injuries; Transfection | 2015 |
Purine-crosslinked injectable chitosan sponges promote oligodendrocyte progenitor cells' attachment and differentiation.
Topics: Animals; Cell Differentiation; Chitosan; Drug Delivery Systems; Guanosine Diphosphate; Myelin Basic Protein; Nerve Regeneration; Oligodendroglia; Porifera; Purines; Spinal Cord Injuries; Stem Cells | 2015 |
Sustained delivery of chondroitinase ABC by poly(propylene carbonate)-chitosan micron fibers promotes axon regeneration and functional recovery after spinal cord hemisection.
Topics: Animals; Axons; Chitosan; Chondroitin ABC Lyase; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation; Motor Activity; Nerve Tissue Proteins; Propane; Rats; Rats, Wistar; Recovery of Function; Regeneration; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors | 2015 |
NT3-chitosan elicits robust endogenous neurogenesis to enable functional recovery after spinal cord injury.
Topics: Analysis of Variance; Animals; Cellular Microenvironment; Chitosan; Electromyography; Evoked Potentials; Fluorescence; Immunohistochemistry; Microscopy, Immunoelectron; Neural Stem Cells; Neurogenesis; Neurotrophin 3; Rats; Recovery of Function; Spinal Cord Injuries | 2015 |
Transcriptome analyses reveal molecular mechanisms underlying functional recovery after spinal cord injury.
Topics: Animals; Cellular Microenvironment; Chitosan; Computational Biology; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Microarray Analysis; Neovascularization, Physiologic; Neurogenesis; Neurotrophin 3; Polymerase Chain Reaction; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries | 2015 |
Harness the power of endogenous neural stem cells by biomaterials to treat spinal cord injury.
Topics: Animals; Biocompatible Materials; Chitosan; Evoked Potentials; Humans; Neural Stem Cells; Neurogenesis; Neurotrophin 3; Spinal Cord Injuries | 2015 |
Chitosan polyplex mediated delivery of miRNA-124 reduces activation of microglial cells in vitro and in rat models of spinal cord injury.
Topics: Animals; Cells, Cultured; Chitosan; Female; Humans; Inflammation; Macrophages; Microglia; Microinjections; MicroRNAs; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Transfection | 2016 |
Chitosan scaffolds induce human dental pulp stem cells to neural differentiation: potential roles for spinal cord injury therapy.
Topics: Adolescent; Animals; beta Catenin; Caspase 3; Cell Differentiation; Cells, Cultured; Chitosan; Dental Pulp; Gene Knockdown Techniques; Humans; Male; Motor Activity; Nerve Growth Factors; Neurons; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Stem Cell Transplantation; Stem Cells; Tissue Scaffolds; Wnt Signaling Pathway; Young Adult | 2016 |
Transplantation of Mesenchymal Stem Cells for Acute Spinal Cord Injury in Rats: Comparative Study between Intralesional Injection and Scaffold Based Transplantation.
Topics: Animals; Bone Marrow Cells; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cells, Cultured; Chitosan; Immunophenotyping; Injections, Intralesional; Lactic Acid; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Microscopy, Fluorescence; Nerve Growth Factors; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Tissue Scaffolds; Transplantation, Homologous | 2016 |
Nano-carrier mediated co-delivery of methyl prednisolone and minocycline for improved post-traumatic spinal cord injury conditions in rats.
Topics: Albumins; Animals; Anti-Inflammatory Agents; Astrocytes; Behavior, Animal; Cell Survival; Chitosan; Drug Carriers; Drug Combinations; Drug Delivery Systems; Female; Lactic Acid; Methylprednisolone; Minocycline; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2017 |
Bioengineering neural stem/progenitor cell-coated tubes for spinal cord injury repair.
Topics: Animals; Animals, Genetically Modified; Cell Differentiation; Chitosan; Green Fluorescent Proteins; Models, Biological; Neurons; Rats; Spinal Cord Injuries; Stem Cell Transplantation; Stem Cells | 2008 |
Delayed implantation of intramedullary chitosan channels containing nerve grafts promotes extensive axonal regeneration after spinal cord injury.
Topics: Animals; Animals, Genetically Modified; Axons; Cell Movement; Chitosan; Female; Nerve Regeneration; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spinal Cord Injuries; Time Factors; Transplants | 2008 |
Repair of thoracic spinal cord injury by chitosan tube implantation in adult rats.
Topics: Animals; Axons; Chitosan; Fluorescein-5-isothiocyanate; Motor Activity; Prosthesis Implantation; Rats; Rats, Wistar; Recovery of Function; Regeneration; Spinal Cord Injuries; Thoracic Vertebrae; Wound Healing | 2009 |
Novel multifunctional polyethylene glycol-transactivating-transduction protein-modified liposomes cross the blood-spinal cord barrier after spinal cord injury.
Topics: Animals; Chitosan; Cholesterol; Disease Models, Animal; Drug Delivery Systems; Gene Products, tat; Iron; Liposomes; Magnetic Resonance Imaging; Magnetics; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Peptide Fragments; Peptides; Polyethylene Glycols; Rats; Spectrophotometry, Atomic; Spinal Cord; Spinal Cord Injuries; Surface Properties | 2010 |
[Experimental study on bone marrow mesenchymal stem cells seeded in chitosan-alginate scaffolds for repairing spinal cord injury].
Topics: Alginates; Animals; Bone Marrow Cells; Chitosan; Coculture Techniques; Female; Glucuronic Acid; Hexuronic Acids; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tissue Engineering; Tissue Scaffolds | 2010 |
Chitosan produces potent neuroprotection and physiological recovery following traumatic spinal cord injury.
Topics: Action Potentials; Animals; Cell Membrane; Chitosan; Female; Guinea Pigs; Lipid Peroxidation; Nanoparticles; Neural Conduction; Neurons; Neuroprotective Agents; Reactive Oxygen Species; Spinal Cord; Spinal Cord Injuries; Tissue Engineering | 2010 |
Endogenous radial glial cells support regenerating axons after spinal cord transection.
Topics: Animals; Axons; Chitosan; Female; Immunohistochemistry; Microscopy, Confocal; Nerve Regeneration; Neuroglia; Neurons; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Stem Cells | 2010 |
A quadruped study on chitosan microspheres containing atorvastatin calcium: preparation, characterization, quantification and in-vivo application.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Chitosan; Heptanoic Acids; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Microspheres; Neuroprotective Agents; Pyrroles; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Wounds and Injuries | 2010 |
Chitosan channels containing spinal cord-derived stem/progenitor cells for repair of subacute spinal cord injury in the rat.
Topics: Animals; Cell Division; Cell Survival; Chitosan; Disease Models, Animal; Ectodysplasins; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hemostatics; Indoles; Locomotion; Neural Stem Cells; Psychomotor Performance; Rats; Rats, Transgenic; Rats, Wistar; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Stem Cell Transplantation | 2010 |
Chitosan/TPP-hyaluronic acid nanoparticles: a new vehicle for gene delivery to the spinal cord.
Topics: Animals; Cell Survival; Cells, Cultured; Chitosan; Disease Models, Animal; DNA; Gene Transfer Techniques; Heterocyclic Compounds; Hyaluronic Acid; Male; Mice; Nanoparticles; Neural Stem Cells; Organophosphorus Compounds; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tissue Culture Techniques | 2012 |
Bone marrow stromal cells-loaded chitosan conduits promote repair of complete transection injury in rat spinal cord.
Topics: Animals; Bone Marrow Cells; Chitosan; Nerve Regeneration; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Stromal Cells; Tissue Engineering; Tissue Scaffolds | 2011 |
The effect of growth factors and soluble Nogo-66 receptor protein on transplanted neural stem/progenitor survival and axonal regeneration after complete transection of rat spinal cord.
Topics: Animals; Axons; Cell Differentiation; Chitosan; Epidermal Growth Factor; Fibroblast Growth Factor 2; GPI-Linked Proteins; Immunoglobulin Fc Fragments; Intercellular Signaling Peptides and Proteins; Ki-67 Antigen; Male; Myelin Proteins; Nerve Regeneration; Neural Stem Cells; Nogo Receptor 1; Oligodendroglia; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, Cell Surface; Recombinant Fusion Proteins; Spinal Cord Injuries | 2012 |
Peptide surface modification of methacrylamide chitosan for neural tissue engineering applications.
Topics: Acrylamides; Amino Acid Sequence; Animals; Cell Adhesion; Cells, Cultured; Chitosan; Coated Materials, Biocompatible; Magnetic Resonance Spectroscopy; Materials Testing; Microscopy, Electron, Scanning; Molecular Structure; Nerve Regeneration; Neurons; Oligopeptides; Rats; Spinal Cord Injuries; Superior Cervical Ganglion; Tissue Engineering | 2007 |
Extramedullary chitosan channels promote survival of transplanted neural stem and progenitor cells and create a tissue bridge after complete spinal cord transection.
Topics: Animals; Animals, Genetically Modified; Cell Differentiation; Cell Survival; Chitosan; Female; Green Fluorescent Proteins; Male; Microscopy, Electron, Transmission; Multipotent Stem Cells; Neurons; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recombinant Proteins; Spinal Cord Injuries; Stem Cell Transplantation; Tissue Engineering; Tissue Scaffolds | 2008 |