Compounds > chitosan
Page last updated: 2024-08-25

chitosan and Disease Models, Animal

chitosan has been researched along with Disease Models, Animal in 578 studies

Research

Studies (578)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (1.90)18.2507
2000's65 (11.25)29.6817
2010's375 (64.88)24.3611
2020's127 (21.97)2.80

Authors

AuthorsStudies
Cui, X; Hao, Y; Li, G; Li, L; Li, Y; Ma, Y; Sha, X; Tang, PF; Wang, H; Wang, L; Zhang, K; Zhang, Z; Zhou, J1
Asghari, A; Gholami, M; Gilanpour, H; Sadeghinezhad, J1
Dai, S; Hu, F; Liu, Y; Meng, T; Qiu, G; Wen, L; Yu, F; Yuan, H; Zhou, X; Zhu, Y1
da Silva, NS; da Silva-Júnior, AA; Daniele-Silva, A; de Andrade, RCLC; de Araújo, NK; de Assis, CF; de Freitas Fernandes-Pedrosa, M; de Medeiros Dantas, JM; De Santis Ferreira, L; de Souza Paiva, W; Furtado, AA; Rocha, HAO; Torres-Rêgo, M; Ururahy, MAG1
Dong, Y; Fu, Z; Huo, J; Ju, J; Lv, J; Niu, W; Wang, L; Zhang, Z1
Chen, X; Cui, Z; Gu, S; Huang, X; Liu, X; Mei, H; Nie, G; Teng, W; Wang, K; Xu, J; Zhang, Y1
Ding, W; Gao, J; Jia, Z; Li, L; Liang, X; Song, M; Xia, L; Zhang, J1
Abdelkader, H; Alany, RG; Fathalla, Z; Moharram, H; Mustafa, WW; Sabry, AM1
Bankhead-Kendall, B; Beagle, J; Breen, K; Dorken Gallastegi, A; Dowling, M; Duggan, MJ; King, CDR; Mashbari, HNA; Naar, L; Pallotta, JB; Velmahos, GC; Wallace, B1
Fallah, M; Khorshidvand, Z; Khosravi, A; Larki-Harchegani, A; Maghsood, AH; Mahboobian, MM1
Amooee, A; Karimi, N; SafiDahaj, F1
Lu, J; Qu, Y; Wang, B; Wang, L; Xia, W1
Danesteh, H; Eftekharian, HR; Fazel, S; Ghadimi, N; Hosseini, SMH; Mardani, M; Mohammadi, H; Naseri, M1
Fan, Y; Jiang, Z; Liu, T; Liu, Z; Peng, N; Zhang, Z1
Kim, HJ; Kim, MA; Lee, CM; Lee, JS; Shin, SR1
Chen, J; Chen, X; Ge, Y; Huang, K; Lin, Z; Lv, Z; Pan, Y; Sun, X; Yao, Q; Yu, H1
El-Maraghy, SA; Motawi, TK; Nady, OM; Sabry, D; Senousy, MA1
Han, P; Jensen, DM; Kriegel, AJ; Liang, M; Liu, J; Lopez-Berestein, G; Mangala, LS; Sood, AK; Usa, K; Widlansky, ME1
Das, S; Mahapatra, PK; Mondal, S; Saha, KD1
Chen, H; Dong, Z; Li, N; Li, Y; Wang, J; Wu, C; Zhang, M; Zhang, Y; Zheng, T; Zou, P1
Karnam, K; Krishna Venuganti, V; Kulkarni, OP; Mahale, A; Sedmaki, K; Sharma, P1
Gong, T; Hou, M; Liu, Y; Wang, Y; Zhang, Y1
Du, Q; Jin, Y; Li, B; Li, R; Shen, X; Xuan, H; Yuan, H; Zhou, J1
Alexandrova, A; Andreeva, M; Atanasova, D; Georgieva, A; Kanzova, H; Petrov, L; Philipov, S; Pramatarov, G; Stoilova, O; Tsvetanova, E1
Fu, Y; Wang, S; Xie, Y; Xiong, H; Xue, G1
Azzi, F; Cunningham, N; Lapointe, R; Lerouge, S; Malaret, T; St-Jean, G; Thébault, P; Trudel, D1
Pu, S; Sun, L; Zhao, K; Zhou, D1
Hu, K; Liu, M; Ni, S; Sun, L; Wang, J; Xu, X; Zhao, X1
Chen, X; Deng, J; Hu, X; Li, D; Peng, M; Xiao, D; Xie, L; Xie, Y; Yang, X; Zhang, X1
Alves, SF; Amaral, AC; Costa, AF; da Silva, JT; Dantas de Sousa, PH; de Menezes, LB; Pellegrini, F1
Koumaravelou, K; Sarathchandiran, I; Selvasudha, N1
Alleva, M; Casadomé-Perales, Á; de la Fuente, JM; Dotti, CG; Esteban, JA; Infantes-Rodríguez, C; Matteis, L; Nebreda, AR; Palomares-Pérez, I; Saido, TC; Saito, T1
Bushkalova, R; Cussac, D; Duployer, B; Farno, M; Girod Fullana, S; Parini, A; Sallerin, B; Tenailleau, C1
Cheng, T; Cheng, Y; Li, J; Qu, Y; Zhang, X1
Akbari, MR; Ghorbani, HM; Honari, H; Saadati, M1
Bukka, R; Khezri, FANZ; Lakshmi, CSR; Nargund, SL; Nidhi, M1
Chen, Z; Fu, C; Gao, F; Geng, F; Hu, Y; Li, J; Ma, X; Zhang, C; Zhang, J1
Chang, SJ; Cherng, JH; Fan, GY; Hong, ZJ; Hsu, SD; Lin, YC; Liu, CC; Wang, YH; Wang, YW1
Alliegro, AA; des Rieux, A; Maugéri, IL; Porcionatto, MA; Teixeira, D; Zamproni, LN1
Kong, ZL; Lai, CS; Sudirman, S; Yan, YL; Yeh, HI1
Li, PF; Liu, XY; Qi, XJ; Qiu, F; Tang, LM; Yang, AH1
Li, P; Liu, Y; Qiao, C; Sun, X; Wen, M; Wu, T; Zhang, W1
Fihurka, O; Khvorova, A; Sanchez-Ramos, J; Sava, V1
Han, Z; Yu, F; Zhang, AY; Zheng, M1
Bhatt, DC; Jindal, DK; Kandav, G1
Chu, K; Han, L; Li, T; Ouyang, H; Qiu, L; Wang, X; Xu, W; Zhang, X1
Cox, BC; Li, D; Naples, JG; Ruckenstein, MJ; Singh, J1
Hashmi, U; Khalil, M; Riaz, R; Rukh Abbas, S1
Abdel Ghaffar, AM; Ali, HE; Radwan, RR1
Kanoujia, J; Kumar, P; Mazhar, I; Parashar, P; Saha, S; Saraf, SA; Yadav, A1
Acartürk, F; Coşkun Cevher, Ş; Demiröz, FT; Özoğul, C; Sarıbaş, S; Tort, S1
Fang, QQ; Hu, YY; Ma, L; Shi, BH; Tan, WQ; Wang, XF; Wang, XW; Zhang, DD; Zhang, T; Zhao, WY; Zheng, B1
de Camargo Forte, MM; Gómez Ribelles, JL; Machado, DC; Mazzuca, R; Viezzer, C1
Batool, S; Dar, MJ; Din, FU; Khaleeq, N; Khan, GM; Kim, DW; Rabia, S1
Arantes, VT; Barcelos, LS; Cassini-Vieira, P; Faraco, AAG; Ferreira, FB; Ferreira, LAM; Goulart, GAC; Martins-Santos, E; Oliveira, CA1
Kumar, TV; Nandi, S; Rahaman, SA; Roy, H1
Banáth, J; Chen, WR; Gallagher, P; Hode, T; Korbelik, M; Lam, SSK; Zeng, H; Zhang, W; Zhao, J1
Dai, F; Lan, G; Li, Q; Lu, F; Shang, S; Wang, Y; Xie, R1
Dua, K; Gandhi, H; Negi, P; Rathore, C; Tambuwala, MM; Vihal, S1
Golmohammadi, R; Hosseini, SMJ; Najar-Peerayeh, S; Tohidi Moghadam, T1
Bayramov, DF; Miao, J; Neff, JA; Patel, EA1
Alhakamy, NA; Anwer, MK; Bhattamisra, SK; Choudhury, H; Lim, WM; Md, S; Radhakrishnan, AK; Safian, NH; Shahzad, N; Shak, AT; Xi, LW1
Abdel-Salam, FS; Amer, MS; Basalious, EB; Elkasabgy, NA; Elkheshen, SA; Mahmoud, AA; Mostafa, AA1
Chai, Z; Chen, H; Chen, W; Chu, R; Feng, W; Li, X; Liang, S; Wang, B; Wang, M; Yu, H; Zheng, L; Zhou, S1
Altıntop, I; Karakükçü, Ç; Öztürk, A; Soyer, Z; Tatlı, M; Yay, AH1
Han, Y; Li, D; Li, H; Li, S; Li, X; Lv, Z; Wang, S; Zhao, W; Zhou, Y1
Bai, K; He, J; Hong, B; Huang, W1
Jang, Y; Jeong, KC; Kang, M; Ma, Z; Meng, S; Tong, Z; Yoon, SD1
Alkhamis, K; Almaaytah, AM; Altaani, BM; Dadou, S; Daradka, MH; Hananeh, W1
Abd Eldaim, MA; Abdallah, AEM; Abdel-Daim, MM; Abdelaziz, SAM; Abdul Rashid, S; Abdullah, AS; Abdullah, LC; Abramson, MJ; Ahmed, HB; Ahmed, MM; Ahn, YC; Alexander, DC; Ando, T; Angelone, AM; Anglani, F; Ap, Y; Arthanari, SK; Axelrad, C; Bai, S; Bakonyi, P; Barnes, E; Beckmann, NA; Bélafi-Bakó, K; Bennett, CM; Bestha, RM; Bitsch, RG; Bradley, CA; Bu, Y; Calò, LA; Cañedo-Villaroya, E; Carlson, L; Caruso, S; Casado-Flores, J; Ceol, M; Cesarino, I; Chen, IL; Chen, R; Chen, X; Chilvers, MI; Cho, WK; Choong, TSY; Conceição-Neto, N; Culver, EL; Dai, X; de Lama Caro-Patón, G; De Rosa, I; Del Prete, D; Dharmage, SC; Dimitriadis, E; Dittakavi, S; Dobrowolski, JC; Edin, S; Elgarawany, GE; Emam, HE; Emmens, RW; Erbas, B; Erwich, JJHM; Farghali, M; Feng, L; Funston, RN; Gabler, NK; Gale, P; Ganesh, M; Gao, J; Gao, L; Gao, X; García-Salido, A; Gatto, R; Gautam, S; Ge, C; Ghogomu, SM; Gianesello, L; Gonçales, VR; Gooch, JL; Gooding, JJ; Gourley, GG; Gu, H; Gu, X; Gu, Z; Guerreri, M; Guillén, M; Hazzaa, SM; Heylen, E; Hicks, R; Hong, X; Hoshi, M; Hu, B; Hu, LX; Hu, R; Hu, S; Huang, J; Huang, K; Hubbard, WB; Hui, J; Hwang, NY; Iannacci, J; Ianus, A; Iglesias-Bouzas, MI; Ihara, I; Iwasaki, M; Jaeger, S; Kandel, YR; Karpińska, G; Kim, HK; Klopfenstein, TJ; Knorr, D; Koók, L; Kotb, S; Kruithof, S; Larsson, P; Laurence, C; Leng, J; Li, H; Li, J; Li, Q; Li, S; Li, X; Li, Z; Lian, J; Liang, JX; Liang, X; Lighaam, LC; Lin, CW; Lin, HC; Lin, J; Ling, A; Liu, J; Liu, P; Liu, YS; Ljuslinder, I; Lo, GH; Lodge, CJ; Löfgren-Burström, A; Lowe, AJ; Lu, M; Lu, N; Lucero-Prisno, DE; Luebbe, KM; Luo, X; Ma, Z; Maes, P; Makuch, M; Malekbala, MR; Mao, Z; Martínez-Romera, I; Marzo, G; Mathew, FM; Mattei, A; Matthijnssens, J; Mayumi, M; Morita, N; Mueller, DS; Mullangi, R; Mummolo, S; Murthi, P; Myte, R; Nabeshima, T; Nakamoto, K; Nehdi, IA; Nemestóthy, N; Niessen, HWM; Noh, JM; Nota, A; Nunes, D; Oh, D; Öhlund, D; Olsen, KM; Ono, H; Osawa, Y; Palmqvist, R; Palombo, M; Park, M; Patience, JF; Peng, Y; Perng, DS; Persano, A; Priante, G; Prince, SJ; Pulipati, S; Pyo, H; Qiu, X; Quan, J; Quaranta, F; Quinzi, V; Rademacher, CJ; Rajaraman, G; Rashid, U; Rauch, JC; Rector, A; Remmerswaal, EBM; Ren, R; Rispens, T; Rocha, GS; Saad, NM; Saito, K; Salamova, A; Sarfaraz, K; Satoshi, A; Schnellmann, RG; Scholpa, NE; Schonhoff, M; Schwartz, KJ; Schwarze, M; Schweer, WP; Seiichi, Y; Serrano-González, A; Severino, J; Shemesh, N; Shi, ZQ; Shike, DW; Shim, YM; Siciliano, PA; Siebenrock, KA; Silva, MKL; Smith, DL; Soltani, S; Song, YM; Spry, ML; Stalker, LA; Stokes, RS; Sullivan, PG; Sun, JM; Sun, S; Svanes, C; Syo, K; Tai, CM; Takashima, S; Tashita, C; Taurino, A; Ten Berge, IJM; Tenuta, AU; Teo, SH; Tilley, RD; Trivedi, RK; Umetsu, K; Unger, PA; van Bruggen, R; van Ham, SM; Van Ranst, M; Vanitha, J; Vekaria, HJ; Venier, M; Venkateshwaran, K; Venkert, A; Vermeulen, E; Wan, C; Wang, H; Wang, N; Wang, P; Wang, T; Wang, X; Wang, Y; Wise, KA; Wolbink, GJ; Wu, J; Wu, P; Wu, S; Wu, Y; Xia, Q; Xin, W; Xiong, Q; Xu, H; Xu, P; Xue, S; Yamamoto, Y; Yamashiro, T; Yan, F; Yan, H; Yan, S; Yan, Y; Yang, JM; Yang, L; Yang, P; Ye, W; Yeh, JH; Yinda, CK; Ying, GG; Ying, L; Yoon, HG; Yu, H; Zainuddin, M; Zakkula, A; Zeller, M; Zeng, Y; Zha, J; Zhang, F; Zhang, H; Zhang, M; Zhang, Q; Zhang, S; Zhang, T; Zhang, Z; Zhao, C; Zhao, J; Zhao, Y; Zhong, Q; Zhu, J; Zingmark, C; Zo, JI; Zou, Y1
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; 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Alper, M; Cevher, E; Mülazimoğlu, L; Orhan, Z; Ozsoy, Y; Sensoy, D; Yildiz, A1
Amidi, M; Bungener, L; Crommelin, DJ; Huckriede, A; Jiskoot, W; Junginger, HE; Romeijn, SG; Verhoef, JC1
Ahuja, N; Al-Mubarak, GA; Alam, HB; Chen, Z; Conran, R; Demoya, M; Ostomel, TA; Rhee, P; Stucky, GD; Velmahos, G1
Beauvais, A; Bose, I; Breger, JA; Doering, TL; Griffith, CL; Kim, MJ; Latge, JP; Liu, H; Mylonakis, E; Osumi, M; Reese, AJ; Sefko, JA; Skau, C; Yang, S; Yoneda, A1
Cho, CS; Kim, IY; Kim, SK; Lee, HC; Na, HS; Park, SS; Seo, JH; Yoo, MK1
Ao, Q; Gong, K; Gong, Y; Liu, X; Wang, A; Wei, Y; Zhang, X; Zhao, N1
Bony, C; Caillot, L; Fabre, S; Jorgensen, C; Moukoko, D; Mrugala, D; Neves, N; Noël, D1
Behrens, P; Brandes, G; Krueger, I; Lenarz, T; Mojallal, H; Stieve, M; Turck, C1
Gu, Q; Hou, C; Liu, Y1
Chae, HJ; Chae, SW; Kim, DS; Kim, EC; Kim, HM; Kim, HR; Lee, GY; Yang, SK; Yun, KJ1
Bertrand, JR; Couvreur, P; de Martimprey, H; Fusco, A; Malvy, C; Santoro, M; Vauthier, C1
Bentley, MV; Defino, HL; Issa, JP; Iyomasa, MM; Regalo, SC; Siéssere, S; Spadaro, AC1
Cai, FC; Deng, B; Li, X; Zhang, XP; Zheng, H; Zhong, M1
Godinez, FS; Henao, J; Johnson, AS; Kircher, SJ; Kozen, BG1
Chang, SH; Cho, CS; Cho, MH; Chung, YS; Hwang, SK; Jin, H; Kim, DY; Kim, HW; Kim, TH; Kwon, JT; Lee, ES; Lee, KH; Minai-Tehrani, A; Noh, MS; Park, SJ; Shin, JY; Woo, M; Xu, CX; Yoon, BI; Youn, HJ1
Cui, X; Gao, Y; Wang, Y; Zhang, B1
Elson, C; Lee, TD; Liwski, RS; Zhou, J1
Athanasiadis, T; Beule, AG; Robinson, BH; Robinson, SR; Shi, Z; Wormald, PJ1
Hong, HY; Kim, IS; Kwon, IC; Lee, BH; Moon, HJ; Park, K; Rhee, K1
Du, LQ; Li, MC; Pang, KP; Wang, SG; Wu, XY1
Biagini, G; Castaldini, C; Ilari, P; Mattioli Belmonte, M; Muzzarelli, RA; Pugnaloni, A; Zucchini, C1
Ciona, C; Costain, DJ; Kennedy, R; Lee, TD; McAlister, VC1
Abe, T; Chanda, J; Kuribayashi, R; Sekine, S; Shibata, Y; Yamagishi, I1
Iinuma, N; Kato, S; Kobayashi, N; Nagano, N; Nishitoba, T; Sato, H; Yagi, M1
Holmes, CC; Miller, TE; Ormrod, DJ1
Bertolami, CN; Fukayama, H; Klokkevold, PR; Sung, EC1
Huang, SK; Leong, KW; Mao, HQ; Roy, K1
Fujita, T; Muranishi, S; Odoriba, T; Okabe, S; Terabe, A; Tozaki, H; Yamamoto, A1
Kimura, Y; Okuda, H; Onoyama, M; Sera, T1
Gu, X; Hou, C; Kang, Y; Wang, Q; Wu, Y; Xiang, Y; Xu, W; Yang, X1
Chen, A; Gu, Q; Hou, C; Zhang, W1
Hayashi, K; Ito, M1
Abe, H; Campeau, JD; Fukasawa, M; Horikawa, H; Masaoka, T; Orita, H; Washio, M1
Bertolami, CN; Fukayama, H; Klokkevold, PR; Subar, P1

Reviews

8 review(s) available for chitosan and Disease Models, Animal

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

2016
Emergent nanotherapies in microcrystal-induced arthritis.
    International immunopharmacology, 2018, Volume: 61

    Topics: Animals; Calcium Phosphates; Chitosan; Chondrocalcinosis; Crystal Arthropathies; Diclofenac; Disease Models, Animal; Gold; Humans; Inflammation Mediators; Nanoparticles; Peptide Hydrolases; Urate Oxidase; Uric Acid

2018
Micelle-like nanoparticles as siRNA and miRNA carriers for cancer therapy.
    Biomedical microdevices, 2018, 07-12, Volume: 20, Issue:3

    Topics: Animals; Cell Line, Tumor; Chitosan; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Disease Models, Animal; Drug Delivery Systems; Humans; Micelles; MicroRNAs; Nanoparticles; Neoplasms; Polyamines; Polyethyleneimine; Polylysine; RNA, Small Interfering

2018
    Acta stomatologica Croatica, 2018, Volume: 52, Issue:2

    Topics: Administration, Oral; Adult; Aged; Air Pollutants; Air Pollution; Alginates; Animals; Animals, Genetically Modified; Axon Guidance; Axons; Barium Sulfate; Bifidobacterium; Capsules; Case-Control Studies; Chitosan; Cities; Colitis; Colony Count, Microbial; Computer Systems; Contrast Media; Dextran Sulfate; Disease Models, Animal; Disease Progression; Environmental Exposure; Feces; Female; Gastrointestinal Tract; Gene Knockdown Techniques; Glucuronic Acid; Hepatitis, Autoimmune; Hexuronic Acids; Humans; Hypergammaglobulinemia; Interleukin-17; Interleukin-33; Interleukin-4; Liver; Male; Mice; Mice, Inbred C57BL; Microbial Viability; Middle Aged; Nerve Tissue Proteins; Particulate Matter; Republic of Korea; Retinal Neurons; Signal Transduction; Th1 Cells; Th2 Cells; Tomography, X-Ray Computed; X-Ray Diffraction; Zebrafish; Zebrafish Proteins

2018
Biomaterial scaffolds used for the regeneration of spinal cord injury (SCI).
    Histology and histopathology, 2014, Volume: 29, Issue:11

    Topics: Alginates; Animals; Apoptosis; Axons; Biocompatible Materials; Chitosan; Collagen; Disease Models, Animal; Drug Delivery Systems; Fibrin; Humans; Hyaluronic Acid; Inflammation; Lactic Acid; Materials Testing; Peptides; Polyesters; Polymers; Sepharose; Spinal Cord; Spinal Cord Injuries; Spinal Cord Regeneration; Stem Cells; Tissue Engineering; Tissue Scaffolds

2014
Challenges for nerve repair using chitosan-siloxane hybrid porous scaffolds.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Humans; Mesenchymal Stem Cells; Myelin Sheath; Nerve Fibers, Myelinated; Nerve Regeneration; Neurodegenerative Diseases; Porosity; Rats; Sciatic Nerve; Silanes; Siloxanes; Tissue Scaffolds; Umbilical Cord

2014
Topical antimicrobials for burn wound infections.
    Recent patents on anti-infective drug discovery, 2010, Volume: 5, Issue:2

    Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Antimicrobial Cationic Peptides; Burns; Chitosan; Disease Models, Animal; Drug Resistance, Microbial; Humans; Iodine; Models, Biological; Patents as Topic; Photochemotherapy; Silver; Skin, Artificial; Wound Infection

2010

Trials

5 trial(s) available for chitosan and Disease Models, Animal

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

2016
Chitosan membranes in a rat model of full-thickness cutaneous wounds: healing and IL-4 levels.
    Journal of wound care, 2015, Volume: 24, Issue:6

    Topics: Animals; Biological Dressings; Chitosan; Disease Models, Animal; Interleukin-4; Male; Rats; Rats, Sprague-Dawley; Skin; Wound Healing; Wounds, Penetrating

2015
Hemostatic efficacy of local chitosan linear polymer granule in an experimental sheep model with severe bleeding of arteria and vena femoralis.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2016, Volume: 22, Issue:3

    Topics: Animals; Chitosan; Disease Models, Animal; Female; Femoral Artery; Femoral Vein; Groin; Hemorrhage; Hemostatic Techniques; Hemostatics; Male; Occlusive Dressings; Polymers; Sheep; Wounds and Injuries

2016
Sprayable chitosan/starch-based sealant reduces adhesion formation in a sheep model for chronic sinusitis.
    The Laryngoscope, 2013, Volume: 123, Issue:1

    Topics: Animals; Chitosan; Chronic Disease; Disease Models, Animal; Endoscopy; Paranasal Sinuses; Postoperative Complications; Prospective Studies; Rhinitis; Sheep; Sinusitis; Starch; Tissue Adhesions

2013

Other Studies

567 other study(ies) available for chitosan and Disease Models, Animal

ArticleYear
Instant hydrogelation encapsulates drugs onto implants intraoperatively against osteoarticular tuberculosis.
    Journal of materials chemistry. B, 2021, 10-06, Volume: 9, Issue:38

    Topics: Animals; Antitubercular Agents; Biocompatible Materials; Calcium Phosphates; Cell Line; Cell Survival; Chitosan; Disease Models, Animal; Drug Carriers; Drug Liberation; Femur; Glycerophosphates; Hydrogels; Isoniazid; Mice; Mycobacterium tuberculosis; Porosity; Prostheses and Implants; Rifampin; Tuberculosis, Osteoarticular

2021
Facile fabrication of an erythropoietin-alginate/chitosan hydrogel and evaluation of its local therapeutic effects on spinal cord injury in rats.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2021, Volume: 29, Issue:2

    Topics: Alginates; Animals; bcl-2-Associated X Protein; Cell Line; Cell Survival; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Erythropoietin; Gene Expression Regulation; Humans; Hydrogels; Male; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2021
All-Trans Retinoic Acid and Doxorubicin Delivery by Folic Acid Modified Polymeric Micelles for the Modulation of Pin1-Mediated DOX-Induced Breast Cancer Stemness and Metastasis.
    Molecular pharmaceutics, 2021, 11-01, Volume: 18, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chitosan; Disease Models, Animal; Doxorubicin; Drug Liberation; Drug Synergism; Female; Folic Acid; Gene Knockdown Techniques; Humans; Mice; Micelles; Nanoparticle Drug Delivery System; Neoplastic Stem Cells; NIMA-Interacting Peptidylprolyl Isomerase; Tissue Distribution; Tretinoin

2021
Production and Characterization of Chitooligosaccharides: Evaluation of Acute Toxicity, Healing, and Anti-Inflammatory Actions.
    International journal of molecular sciences, 2021, Sep-30, Volume: 22, Issue:19

    Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents; Bacillus; Biocompatible Materials; Cell Movement; Cell Survival; Chitosan; Cytokines; Disease Models, Animal; Ear Diseases; Edema; Female; Fibroblasts; Glycoside Hydrolases; Hydrolysis; Inflammation; Leukocytes; Male; Mice; Mice, Inbred BALB C; Oligosaccharides; Wound Healing

2021
Effects of molecular weight of chitosan on anti-inflammatory activity and modulation of intestinal microflora in an ulcerative colitis model.
    International journal of biological macromolecules, 2021, Dec-15, Volume: 193, Issue:Pt B

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Chitosan; Colitis, Ulcerative; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred ICR; Molecular Weight; RAW 264.7 Cells

2021
Local delivery of biocompatible lentinan/chitosan composite for prolonged inhibition of postoperative breast cancer recurrence.
    International journal of biological macromolecules, 2022, Jan-01, Volume: 194

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chitosan; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Lentinan; Mice; Postoperative Care; Recurrence; Spectrum Analysis; Treatment Outcome; Xenograft Model Antitumor Assays

2022
Up-regulation of caveolin 1 mediated by chitosan activates Wnt/ β-catenin pathway in chronic refractory wound diabetic rat model.
    Bioengineered, 2022, Volume: 13, Issue:1

    Topics: Animals; beta Catenin; Binding Sites; Caveolin 1; Cell Line; Chitosan; Diabetes Complications; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Indenes; Male; Molecular Docking Simulation; Protein Binding; Rats; Sequence Analysis, RNA; Sulfonamides; Wnt Signaling Pathway; Wound Healing

2022
Hybrid thermosensitive-mucoadhesive
    Drug delivery, 2022, Volume: 29, Issue:1

    Topics: Administration, Topical; Animals; Carnosine; Chemistry, Pharmaceutical; Chitosan; Cornea; Corneal Ulcer; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Liberation; Gels; Methylcellulose; Poloxamer; Rabbits; Rheology; Temperature; Wound Healing

2022
Chitosan-based lifefoam improves survival in lethal noncompressible abdominal bleeding in swine.
    Surgery, 2022, Volume: 172, Issue:1

    Topics: Animals; Chitosan; Disease Models, Animal; Fluid Therapy; Hemorrhage; Hemostatic Techniques; Hemostatics; Humans; Swine

2022
Novel naltrexone hydrochloride nanovaccine based on chitosan nanoparticles promotes induction of Th1 and Th17 immune responses resulting in protection against Toxoplasma gondii tachyzoites in a mouse model.
    International journal of biological macromolecules, 2022, May-31, Volume: 208

    Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; Chitosan; Disease Models, Animal; Immunity, Humoral; Interleukin-17; Interleukin-4; Mice; Mice, Inbred BALB C; Naltrexone; Nanoparticles; Protozoan Proteins; Protozoan Vaccines; Recombinant Proteins; Th1 Cells; Th17 Cells; Toxoplasma

2022
Comparison of the effect of PerClot® powder and a chitosan derivative on postoperative intra-abdominal adhesions in rat animal models.
    Polski przeglad chirurgiczny, 2021, Dec-22, Volume: 94, Issue:2

    Topics: Animals; Chitosan; Disease Models, Animal; Hemostatics; Humans; Male; Powders; Rats; Rats, Wistar; Tissue Adhesions

2021
Chitosan oligosaccharides exert neuroprotective effects
    Food & function, 2022, May-23, Volume: 13, Issue:10

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Chitosan; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt

2022
Hemostatic efficacy of composite polysaccharide powder (starch-chitosan) for emergency bleeding control: An animal model study.
    Surgery, 2022, Volume: 172, Issue:3

    Topics: Animals; Chitosan; Disease Models, Animal; Hemorrhage; Hemostasis; Hemostatics; Iran; Male; Polysaccharides; Powders; Rabbits; Starch; Water

2022
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
    Microbiology spectrum, 2022, 08-31, Volume: 10, Issue:4

    Topics: Animals; Bacillus coagulans; Chitosan; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Interleukin-4; Mice; Oligosaccharides

2022
Chemo-photothermal therapeutic effect of chitosan-gelatin hydrogels containing methotrexate and melanin on a collagen-induced arthritis mouse model.
    International journal of biological macromolecules, 2022, Oct-01, Volume: 218

    Topics: Animals; Arthritis, Experimental; Chitosan; Disease Models, Animal; Doxorubicin; Gelatin; Hydrogels; Infrared Rays; Melanins; Methotrexate; Mice; Phototherapy

2022
Immunomodulation of MiRNA-223-based nanoplatform for targeted therapy in retinopathy of prematurity.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 350

    Topics: Animals; Chitosan; Disease Models, Animal; Folic Acid; Humans; Immunomodulation; Infant, Newborn; Inflammation; Interleukin-6; Mice; MicroRNAs; Neovascularization, Pathologic; Oxygen; Retinopathy of Prematurity; Silicon Dioxide

2022
Cromolyn chitosan nanoparticles reverse the DNA methylation of RASSF1A and p16 genes and mitigate DNMT1 and METTL3 expression in breast cancer cell line and tumor xenograft model in mice.
    Chemico-biological interactions, 2022, Sep-25, Volume: 365

    Topics: Animals; Ascites; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Chitosan; Cromolyn Sodium; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Heterografts; Humans; Mice; Nanoparticles; RNA, Neoplasm

2022
Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2022, 11-02, Volume: 30, Issue:11

    Topics: Angiotensin II; Animals; Chitosan; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Fibrosis; Humans; Hypertension; Mice; Mice, Inbred Strains; Mice, Knockout, ApoE; MicroRNAs; Thiolester Hydrolases

2022
Morin-VitaminE-β-CyclodextrinInclusionComplexLoadedChitosanNanoparticles (M-Vit.E-CD-CSNPs) Ameliorate Arsenic-Induced Hepatotoxicityina Murine Model.
    Molecules (Basel, Switzerland), 2022, Sep-08, Volume: 27, Issue:18

    Topics: Animals; Antioxidants; Arsenic; beta-Cyclodextrins; Chitosan; Disease Models, Animal; Drinking Water; Drug Carriers; Flavones; Mice; Nanoparticles; Reactive Oxygen Species; Vitamin E; Vitamins

2022
Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota.
    Molecules (Basel, Switzerland), 2022, Sep-15, Volume: 27, Issue:18

    Topics: Animals; Berberine; Chitosan; Claudin-2; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Eosine Yellowish-(YS); Excipients; Gastrointestinal Microbiome; Hematoxylin; Humans; Hypromellose Derivatives; Interleukin-6; Mice; Mice, Inbred C57BL; Occludin; Pectins; RNA, Ribosomal, 16S

2022
HDAC5 RNA interference ameliorates acute renal injury by upregulating KLF2 and inhibiting NALP3 expression in a mouse model of oxalate nephropathy.
    International immunopharmacology, 2022, Volume: 112

    Topics: Acute Kidney Injury; Animals; Chitosan; Creatinine; Disease Models, Animal; Histone Deacetylases; Inflammasomes; Interleukin-1beta; Kruppel-Like Transcription Factors; Lipocalin-2; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Oxalates; RNA Interference; RNA, Small Interfering; Transcription Factors; Tumor Necrosis Factor-alpha

2022
The Anti-inflammatory Effect of Chitosan Oligosaccharide on Heart Failure in Mice.
    BioMed research international, 2022, Volume: 2022

    Topics: Animals; Anti-Inflammatory Agents; Chitosan; Disease Models, Animal; Heart Failure; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oligosaccharides; Ventricular Remodeling

2022
Shape-Memory-Reduced Graphene/Chitosan Cryogels for Non-Compressible Wounds.
    International journal of molecular sciences, 2023, Jan-10, Volume: 24, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Chitosan; Cryogels; Disease Models, Animal; Dopamine; Graphite; Hemostatics; Mice

2023
Effect of Chitosan-Diosgenin Combination on Wound Healing.
    International journal of molecular sciences, 2023, Mar-06, Volume: 24, Issue:5

    Topics: Animals; Antioxidants; Chitosan; Diosgenin; Disease Models, Animal; Ethanol; Glutathione; Mice; Wound Healing

2023
Eudragit-coated chitosan-tripterygium glycoside conjugate microspheres alleviate DSS-induced experimental colitis by inhibiting the TLR4/NF-κB signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 158

    Topics: Animals; Cardiac Glycosides; Chitosan; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Glycosides; Mice; Microspheres; NF-kappa B; Renal Dialysis; Signal Transduction; Toll-Like Receptor 4; Tripterygium

2023
T cell-loaded injectable chitosan scaffold shows short-term efficacy in localised cancer immunotherapy in mice.
    Biomaterials science, 2023, May-16, Volume: 11, Issue:10

    Topics: Animals; Chitosan; Disease Models, Animal; Humans; Hydrogels; Immunotherapy; Mice; Mice, Inbred C57BL; Neoplasms; T-Lymphocytes

2023
Gentiopicroside-Loaded Chitosan Nanoparticles Inhibit TNF-α-Induced Proliferation and Inflammatory Response in HaCaT Keratinocytes and Ameliorate Imiquimod-Induced Dermatitis Lesions in Mice.
    International journal of nanomedicine, 2023, Volume: 18

    Topics: Animals; Cell Proliferation; Chitosan; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Interleukin-17; Interleukin-6; Keratinocytes; Mice; Mice, Inbred BALB C; Nanoparticles; Psoriasis; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2023
Nose to brain delivery of Astragaloside IV by β-Asarone modified chitosan nanoparticles for multiple sclerosis therapy.
    International journal of pharmaceutics, 2023, Sep-25, Volume: 644

    Topics: Animals; Brain; Chitosan; Disease Models, Animal; Mice; Multiple Sclerosis

2023
Metformin-Loaded Chitosan Hydrogels Suppress Bladder Tumor Growth in an Orthotopic Mouse Model via Intravesical Administration.
    Molecules (Basel, Switzerland), 2023, Sep-20, Volume: 28, Issue:18

    Topics: Administration, Intravesical; Animals; Chitosan; Disease Models, Animal; Hydrogels; Metformin; Mice; Urinary Bladder; Urinary Bladder Neoplasms

2023
Fluconazole and propolis co-encapsulated in chitosan nanoparticles for the treatment of vulvovaginal candidiasis in a murine model.
    Medical mycology, 2023, Nov-06, Volume: 61, Issue:11

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; Chitosan; Disease Models, Animal; Female; Fluconazole; Mice; Microbial Sensitivity Tests; Nanoparticles; Propolis; Rodent Diseases

2023
Interaction pattern and
    Drug development and industrial pharmacy, 2019, Volume: 45, Issue:11

    Topics: Administration, Oral; Animals; Chitosan; Cholesterol, Dietary; Delayed-Action Preparations; Disease Models, Animal; Drug Administration Schedule; Drug Carriers; Drug Compounding; Drug Liberation; Female; Humans; Hyperlipidemias; Mice; Molecular Docking Simulation; Nanoparticles; Particle Size; Proton Magnetic Resonance Spectroscopy; Simvastatin; Spectroscopy, Fourier Transform Infrared

2019
Inhibition of p38 MAPK in the brain through nasal administration of p38 inhibitor loaded in chitosan nanocapsules.
    Nanomedicine (London, England), 2019, Volume: 14, Issue:18

    Topics: Administration, Intranasal; Alzheimer Disease; Animals; Benzamides; Brain; Cell Line; Chitosan; Disease Models, Animal; Drug Delivery Systems; Female; Male; Mice; Nanocapsules; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridones; Rats, Wistar

2019
Alginate-chitosan PEC scaffolds: A useful tool for soft tissues cell therapy.
    International journal of pharmaceutics, 2019, Nov-25, Volume: 571

    Topics: Alginates; Animals; Biocompatible Materials; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Combined Modality Therapy; Disease Models, Animal; Feasibility Studies; Female; Humans; Ischemia; Male; Materials Testing; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Polyelectrolytes; Porosity; Primary Cell Culture; Rats; Rats, Inbred Lew; Tissue Engineering; Tissue Scaffolds

2019
Triamcinolone acetonide-chitosan coated liposomes efficiently treated retinal edema as eye drops.
    Experimental eye research, 2019, Volume: 188

    Topics: Administration, Ophthalmic; Animals; Biological Availability; Blood-Retinal Barrier; Chitosan; Coated Materials, Biocompatible; Disease Models, Animal; Drug Delivery Systems; Female; Fluorescent Dyes; Glucocorticoids; Intraocular Pressure; Intravitreal Injections; Liposomes; Ophthalmic Solutions; Papilledema; Rats; Rats, Inbred BN; Tomography, Optical Coherence; Triamcinolone Acetonide; Visual Acuity

2019
IpaD-loaded N-trimethyl Chitosan Nanoparticles Can Efficiently Protect Guinea Pigs against Shigella flexneri.
    Iranian journal of immunology : IJI, 2019, Volume: 16, Issue:3

    Topics: Administration, Oral; Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Proteins; Chitosan; Disease Models, Animal; Dysentery, Bacillary; Guinea Pigs; Humans; Immunity, Mucosal; Immunization; Immunoglobulin A; Immunoglobulin G; Nanoparticles; Protein Domains; Shigella flexneri; Shigella Vaccines; Vaccination

2019
Pharmacokinetic study and brain tissue analysis of Zolmitriptan loaded chitosan nanoparticles in rats by LC-MS method.
    International journal of biological macromolecules, 2020, Jan-01, Volume: 142

    Topics: Administration, Intranasal; Animals; Brain; Chitosan; Chromatography, Liquid; Disease Models, Animal; Male; Migraine Disorders; Nanoparticles; Oxazolidinones; Particle Size; Rats; Rats, Wistar; Tandem Mass Spectrometry; Tryptamines

2020
A feasible biocompatible hydrogel film embedding Periplaneta americana extract for acute wound healing.
    International journal of pharmaceutics, 2019, Nov-25, Volume: 571

    Topics: Acrylic Resins; Animals; Bandages, Hydrocolloid; Biocompatible Materials; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Glycerol; Humans; Hydrogels; Male; Materia Medica; Methylgalactosides; Mice; Periplaneta; Polyvinyl Alcohol; Re-Epithelialization; Skin

2019
Evaluation of Chitosan-based Dressings in a Swine Model of Artery-Injury-Related Shock.
    Scientific reports, 2019, 10-10, Volume: 9, Issue:1

    Topics: Animals; Bandages; Chitosan; Disease Models, Animal; Femoral Artery; Hemorrhage; Hemostasis; Male; Materials Testing; Resuscitation; Shock; Swine; Treatment Outcome

2019
Decreased viability and neurite length in neural cells treated with chitosan-dextran sulfate nanocomplexes.
    Neurotoxicology, 2020, Volume: 76

    Topics: Animals; Cell Line, Tumor; Cell Survival; Chemokine CXCL12; Chitosan; Dextran Sulfate; Disease Models, Animal; Drug Carriers; Encephalitis; Female; Humans; Jurkat Cells; Mice, Inbred C57BL; Nanoparticles; Neural Stem Cells; Neurites; Stroke

2020
Histological evidence of chitosan-encapsulated curcumin suppresses heart and kidney damages on streptozotocin-induced type-1 diabetes in mice model.
    Scientific reports, 2019, 10-23, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Curcumin; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Diabetic Nephropathies; Disease Models, Animal; Heart; Kidney; Male; Mice; Mice, Inbred C57BL; Streptozocin

2019
Anti-depressant effect of curcumin-loaded guanidine-chitosan thermo-sensitive hydrogel by nasal delivery.
    Pharmaceutical development and technology, 2020, Volume: 25, Issue:3

    Topics: Administration, Intranasal; Animals; Antidepressive Agents; Chitosan; Curcumin; Depression; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Liberation; Guanidine; Hydrogels; Male; Mice; Mice, Inbred ICR; Solubility; Temperature; Viscosity

2020
Chitosan Hydrogel Enhances the Therapeutic Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells for Myocardial Infarction by Alleviating Vascular Endothelial Cell Pyroptosis.
    Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:1

    Topics: Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Disease Models, Animal; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydrogels; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Transgenic; Myocardial Infarction; Paracrine Communication; Pyroptosis; Recovery of Function; Ventricular Function, Left

2020
Enriched chitosan nanoparticles loaded with siRNA are effective in lowering Huntington's disease gene expression following intranasal administration.
    Nanomedicine : nanotechnology, biology, and medicine, 2020, Volume: 24

    Topics: Administration, Intranasal; Animals; Chitosan; Disease Models, Animal; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Nanoparticles; RNA, Small Interfering

2020
A cerium oxide loaded glycol chitosan nano-system for the treatment of dry eye disease.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 12-10, Volume: 315

    Topics: Animals; Antioxidants; Cerium; Chitosan; Conjunctiva; Cornea; Disease Models, Animal; Dry Eye Syndromes; Female; Mice; Mice, Inbred C57BL; Nanoparticles; Reactive Oxygen Species; Solubility; Superoxide Dismutase; Tears

2019
Targeting kidneys by superparamagnetic allopurinol loaded chitosan coated nanoparticles for the treatment of hyperuricemic nephrolithiasis.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2019, Volume: 27, Issue:2

    Topics: Administration, Oral; Allopurinol; Animals; Chemical Precipitation; Chitosan; Disease Models, Animal; Drug Delivery Systems; Kidney; Magnetite Nanoparticles; Mice; Nanoparticles; Nephrolithiasis; Oxonic Acid; Uric Acid

2019
Evaluation of intestinal permeation enhancement with carboxymethyl chitosan-rhein polymeric micelles for oral delivery of paclitaxel.
    International journal of pharmaceutics, 2020, Jan-05, Volume: 573

    Topics: Administration, Oral; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Intestinal Mucosa; Male; Mice; Micelles; Neoplasms; Paclitaxel; Permeability; Rats; Tissue Distribution; Verapamil

2020
Intratympanic Diltiazem-Chitosan Hydrogel as an Otoprotectant Against Cisplatin-Induced Ototoxicity in a Mouse Model.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2020, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents; Chitosan; Cisplatin; Diltiazem; Disease Models, Animal; Drug Carriers; Evoked Potentials, Auditory, Brain Stem; Female; Hydrogels; Injection, Intratympanic; Mice; Mice, Inbred CBA; Ototoxicity

2020
Chitosan coated liposomes (CCL) containing triamcinolone acetonide for sustained delivery: A potential topical treatment for posterior segment diseases.
    International journal of biological macromolecules, 2020, Jan-15, Volume: 143

    Topics: Animals; Chitosan; Choroidal Neovascularization; Coated Materials, Biocompatible; Delayed-Action Preparations; Disease Models, Animal; Humans; Liposomes; Rats; Triamcinolone

2020
Gamma radiation preparation of chitosan nanoparticles for controlled delivery of memantine.
    Journal of biomaterials applications, 2020, Volume: 34, Issue:8

    Topics: Acetic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antiparkinson Agents; Brain; Chitosan; Disease Models, Animal; Drug Compounding; Drug Liberation; Gamma Rays; Humans; Interleukins; Male; Memantine; Morris Water Maze Test; Nanocapsules; Rats; Solubility; Tumor Necrosis Factor-alpha; Water

2020
Appraisal of anti-gout potential of colchicine-loaded chitosan nanoparticle gel in uric acid-induced gout animal model.
    Archives of physiology and biochemistry, 2022, Volume: 128, Issue:2

    Topics: Animals; Chitosan; Colchicine; Disease Models, Animal; Gout; Nanoparticles; Uric Acid

2022
The effect of a new wound dressing on wound healing: Biochemical and histopathological evaluation.
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:1

    Topics: Alginates; Animals; Anti-Bacterial Agents; Bandages; Biocompatible Materials; Chitosan; Collagen; Disease Models, Animal; Doxycycline; Fibroblast Growth Factor 2; Hyperglycemia; Matrix Metalloproteinases; Nanofibers; Neovascularization, Physiologic; Rats; Rats, Wistar; Tissue Inhibitor of Metalloproteinases; Vascular Endothelial Growth Factor A; von Willebrand Factor; Wound Healing; Wounds and Injuries

2020
Chitosan-calcium alginate dressing promotes wound healing: A preliminary study.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2020, Volume: 28, Issue:3

    Topics: Alginates; Animals; Bandages; Chitosan; Disease Models, Animal; Hemostatics; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Skin; Spectroscopy, Fourier Transform Infrared; Surgical Wound; Wound Healing

2020
A new waterborne chitosan-based polyurethane hydrogel as a vehicle to transplant bone marrow mesenchymal cells improved wound healing of ulcers in a diabetic rat model.
    Carbohydrate polymers, 2020, Mar-01, Volume: 231

    Topics: Animals; Biodegradable Plastics; Chitosan; Diabetes Complications; Disease Models, Animal; Foot Ulcer; Humans; Hydrogels; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Polyurethanes; Rats; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; Wound Healing

2020
Rifampicin-loaded nanotransferosomal gel for treatment of cutaneous leishmaniasis: passive targeting via topical route.
    Nanomedicine (London, England), 2020, Volume: 15, Issue:2

    Topics: Administration, Topical; Animals; Antiprotozoal Agents; Chitosan; Disease Models, Animal; Drug Delivery Systems; Flow Cytometry; Humans; Leishmaniasis, Cutaneous; Macrophages; Mice; Nanogels; Nanoparticles; Polyethylene Glycols; Polyethyleneimine; Rats; Rifampin

2020
Retinoic acid-loaded solid lipid nanoparticles surrounded by chitosan film support diabetic wound healing in in vivo study.
    Colloids and surfaces. B, Biointerfaces, 2020, Volume: 188

    Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Carriers; Lipids; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Particle Size; Surface Properties; Tretinoin; Wound Healing

2020
Current Development on Chitosan-based Antimicrobial Drug Formulations for the Wound Healing.
    Current drug discovery technologies, 2020, Volume: 17, Issue:4

    Topics: Administration, Cutaneous; Animals; Anti-Bacterial Agents; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Hydrogels; Macrophage Activation; Nanoparticles; Skin; Skin Absorption; Wound Healing

2020
N-dihydrogalactochitosan-supported tumor control by photothermal therapy and photothermal therapy-generated vaccine.
    Journal of photochemistry and photobiology. B, Biology, 2020, Volume: 204

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Caspase 1; Caspase Inhibitors; Cell Line, Tumor; Cell Survival; Chitosan; Disease Models, Animal; Fas Ligand Protein; fas Receptor; Fluorescein; Lasers, Semiconductor; Lung Neoplasms; Mice; Phototherapy; T-Lymphocytes, Regulatory

2020
A self-adapting hydrogel based on chitosan/oxidized konjac glucomannan/AgNPs for repairing irregular wounds.
    Biomaterials science, 2020, Mar-31, Volume: 8, Issue:7

    Topics: Animals; Cell Line; Chitosan; Disease Models, Animal; Escherichia coli; Hydrogels; Mannans; Metal Nanoparticles; Mice; Rabbits; Schiff Bases; Silver; Staphylococcus aureus; Tissue Adhesives; Tranexamic Acid; Wound Healing

2020
Efficacy of resveratrol encapsulated microsponges delivered by pectin based matrix tablets in rats with acetic acid-induced ulcerative colitis.
    Drug development and industrial pharmacy, 2020, Volume: 46, Issue:3

    Topics: Acetic Acid; Animals; Antioxidants; Chemistry, Pharmaceutical; Chitosan; Colitis, Ulcerative; Colon; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Particle Size; Pectins; Rats; Rats, Wistar; Resveratrol; Tablets

2020
Synergistic Antibacterial Activity and Wound Healing Properties of Selenium-Chitosan-Mupirocin Nanohybrid System: An in Vivo Study on Rat Diabetic Staphylococcus aureus Wound Infection Model.
    Scientific reports, 2020, 02-18, Volume: 10, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Chitosan; Diabetes Complications; Disease Models, Animal; Drug Synergism; Humans; Mupirocin; Nanostructures; Rats; Selenium; Wound Healing; Wound Infection

2020
Novel Antimicrobial Peptides Formulated in Chitosan Matrices are Effective Against Biofilms of Multidrug-Resistant Wound Pathogens.
    Military medicine, 2020, 01-07, Volume: 185, Issue:Suppl 1

    Topics: Animals; Bandages; Biofilms; Chitosan; Disease Models, Animal; Drug Resistance, Multiple; Gels; Pore Forming Cytotoxic Proteins; Swine; Wound Healing

2020
Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease.
    International journal of pharmaceutics, 2020, Apr-15, Volume: 579

    Topics: Administration, Intranasal; alpha-Synuclein; Animals; Blood-Brain Barrier; Cell Line, Tumor; Chitosan; Disease Models, Animal; Dopamine Agonists; Drug Carriers; Female; Haloperidol; Humans; Male; Nanoparticles; Neurons; Oxidopamine; Parkinson Disease, Secondary; Particle Size; Rats; Tetrahydronaphthalenes; Thiophenes; Toxicity Tests, Acute

2020
In-situ forming chitosan implant-loaded with raloxifene hydrochloride and bioactive glass nanoparticles for treatment of bone injuries: Formulation and biological evaluation in animal model.
    International journal of pharmaceutics, 2020, Apr-30, Volume: 580

    Topics: Animals; Bone Density Conservation Agents; Bone Regeneration; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Evaluation, Preclinical; Drug Implants; Glass; Male; Nanoparticles; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tibia; Treatment Outcome

2020
Surface chemistry governs the sub-organ transfer, clearance and toxicity of functional gold nanoparticles in the liver and kidney.
    Journal of nanobiotechnology, 2020, Mar-14, Volume: 18, Issue:1

    Topics: Animals; Chitosan; Cytosol; Disease Models, Animal; Gene Expression; Gold; Kidney; Kinetics; Liver; Male; Metal Nanoparticles; Mice; Mice, Inbred ICR; Particle Size; Polyethylene Glycols; Polyethyleneimine; Rats; Rats, Wistar; Tissue Distribution; Transcriptome

2020
A novel hemostatic scaffold material and the importance of scaffold formation on ending hemorrhage: An experimental rat study.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2020, Volume: 26, Issue:2

    Topics: Animals; Chitosan; Diatomaceous Earth; Disease Models, Animal; Hemorrhage; Hemostasis; Hemostatics; Male; Rats; Rats, Wistar

2020
Enzymatic preparation of chitooligosaccharides and their anti-obesity application.
    Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:7

    Topics: Animals; Anti-Obesity Agents; Chitin; Chitosan; Cholesterol, HDL; Cholesterol, LDL; Diet, High-Fat; Disease Models, Animal; Fatty Acids, Nonesterified; Glycoside Hydrolases; Hydrogen-Ion Concentration; Hydrolysis; Male; Mice; Obesity; Oligosaccharides; Pseudoalteromonas; Temperature; Triglycerides

2020
Antioxidant Capacity and Hepatoprotective Role of Chitosan-Stabilized Selenium Nanoparticles in Concanavalin A-Induced Liver Injury in Mice.
    Nutrients, 2020, Mar-23, Volume: 12, Issue:3

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chitosan; Concanavalin A; Disease Models, Animal; Free Radical Scavengers; Glutathione Peroxidase; Liver; Male; Mice; Nanoparticles; Oxidation-Reduction; Oxidative Stress; Powders; Reactive Oxygen Species; Selenium; Spray Drying; Superoxide Dismutase

2020
Selective Killing of Shiga Toxin-Producing
    ACS applied materials & interfaces, 2020, Apr-22, Volume: 12, Issue:16

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Caenorhabditis elegans; Chickens; Chitosan; Disease Models, Animal; Escherichia coli Infections; Gastrointestinal Diseases; Gastrointestinal Tract; Microbial Viability; Nanoparticles; Shiga-Toxigenic Escherichia coli

2020
Oral Delivery of Teriparatide Using a Nanoemulsion System: Design, in Vitro and in Vivo Evaluation.
    Pharmaceutical research, 2020, Apr-06, Volume: 37, Issue:4

    Topics: Administration, Oral; Animals; Bone Density Conservation Agents; Cell Survival; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Stability; Excipients; Female; Mice; Nanoparticles; NIH 3T3 Cells; Oleic Acid; Osteoporosis; Particle Size; Rabbits; Rats, Sprague-Dawley; Surface Properties; Teriparatide

2020
Chitosan-glucan complex hollow fibers reinforced collagen wound dressing embedded with aloe vera. II. Multifunctional properties to promote cutaneous wound healing.
    International journal of pharmaceutics, 2020, May-30, Volume: 582

    Topics: Aloe; Animals; Anti-Bacterial Agents; Bacteria; Bandages; Cells, Cultured; Chitosan; Disease Models, Animal; Fibrillar Collagens; Glucans; Humans; Male; Mycelium; Plant Extracts; Rats, Wistar; Schizophyllum; Skin; Wound Healing; Wounds and Injuries

2020
Effect of the cagW-based gene vaccine on the immunologic properties of BALB/c mouse: an efficient candidate for Helicobacter pylori DNA vaccine.
    Journal of nanobiotechnology, 2020, Apr-21, Volume: 18, Issue:1

    Topics: Animals; Antibodies, Bacterial; Bacterial Proteins; CD8-Positive T-Lymphocytes; Chitosan; Disease Models, Animal; Helicobacter Infections; Helicobacter pylori; Immunity, Cellular; Interferon-gamma; Mice; Mice, Inbred BALB C; Nanoparticles; Plasmids; Transfection; Vaccines, DNA; Virulence Factors

2020
IGF-1C domain-modified chitosan hydrogel accelerates cutaneous wound healing by promoting angiogenesis.
    Future medicinal chemistry, 2020, Volume: 12, Issue:13

    Topics: Animals; Carbohydrate Conformation; Cell Proliferation; Cells, Cultured; Chitosan; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Hydrogels; Insulin-Like Growth Factor I; Mice; Mice, Transgenic; Neovascularization, Pathologic; Wound Healing

2020
Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti-Inflammatory, and Antiapoptotic Properties.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Chitosan; Disease Models, Animal; Heart; Humans; Male; Myocarditis; Rats

2020
Thymoquinone-encapsulated chitosan nanoparticles coated with polysorbate 80 as a novel treatment agent in a reserpine-induced depression animal model.
    Physiology & behavior, 2020, 08-01, Volume: 222

    Topics: Animals; Benzoquinones; Chitosan; Depression; Disease Models, Animal; Nanoparticles; Polysorbates; Rats; Reserpine

2020
The Effects of the Marine-Derived Polysaccharides Laminarin and Chitosan on Aspects of Colonic Health in Pigs Challenged with Dextran Sodium Sulphate.
    Marine drugs, 2020, May-16, Volume: 18, Issue:5

    Topics: Animals; Chitosan; Colitis; Dextrans; Dietary Supplements; Disease Models, Animal; Glucans; Intestinal Mucosa; Male; Polysaccharides; Protective Agents; Random Allocation; Swine

2020
Effect of chitosan and Dysphania ambrosioides on the bone regeneration process: A randomized controlled trial in an animal model.
    Microscopy research and technique, 2020, Volume: 83, Issue:10

    Topics: Animals; Bone Regeneration; Chenopodium ambrosioides; Chitosan; Disease Models, Animal; Male; Rats; Rats, Wistar

2020
Callophycin A loaded chitosan and spicules based nanocomposites as an alternative strategy to overcome vaginal candidiasis.
    International journal of biological macromolecules, 2020, Oct-15, Volume: 161

    Topics: Animals; Candidiasis, Vulvovaginal; Carbolines; Chitosan; Disease Models, Animal; Female; Humans; Mice; Nanocomposites

2020
Silencing adenosine A2a receptor enhances dendritic cell-based cancer immunotherapy.
    Nanomedicine : nanotechnology, biology, and medicine, 2020, Volume: 29

    Topics: Adenosine A2 Receptor Antagonists; Animals; Breast Neoplasms; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Chitosan; Dendritic Cells; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Lactic Acid; Mammary Neoplasms, Animal; Mice; Nanoparticles; Polyethylene Glycols; Receptor, Adenosine A2A; RNA, Small Interfering; T-Lymphocytes, Cytotoxic

2020
Ultrasound-assisted transdermal delivery of alendronate for the treatment of osteoporosis.
    Acta biochimica Polonica, 2020, Jun-19, Volume: 67, Issue:2

    Topics: Administration, Cutaneous; Alendronate; Animals; Biological Availability; Bone Density Conservation Agents; Calcium; Chitosan; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Male; Nanoparticles; Osteoporosis; Particle Size; Permeability; Rats; Rats, Sprague-Dawley; Skin; Transdermal Patch; Treatment Outcome; Ultrasonic Waves

2020
Study of injectable Blueberry anthocyanins-loaded hydrogel for promoting full-thickness wound healing.
    International journal of pharmaceutics, 2020, Aug-30, Volume: 586

    Topics: Animals; Anthocyanins; Anti-Inflammatory Agents; Antioxidants; Blueberry Plants; Chitosan; Collagen; Disease Models, Animal; Hyaluronic Acid; Hydrogels; Injections; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Time Factors; Wound Healing

2020
Effect of chitooligosaccharides on human gut microbiota and antiglycation.
    Carbohydrate polymers, 2020, Aug-15, Volume: 242

    Topics: Adult; Animals; China; Chitin; Chitosan; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Gastrointestinal Microbiome; Glycosylation; Healthy Volunteers; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Oligosaccharides

2020
Repair of osteochondral defect using icariin-conditioned serum combined with chitosan in rabbit knees.
    BMC complementary medicine and therapies, 2020, Jun-22, Volume: 20, Issue:1

    Topics: Animals; Biocompatible Materials; Cartilage, Articular; Cell Line; China; Chitosan; Culture Media, Conditioned; Disease Models, Animal; Drug Therapy, Combination; Flavonoids; Knee Injuries; Male; Mice; Rabbits; Range of Motion, Articular; Serum; Tissue Engineering; Wound Healing

2020
Efficacy of topical platelet-rich plasma and chitosan co-administration on Candida albicans-infected partial thickness burn wound healing.
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:8

    Topics: Animals; Burns; Candida albicans; Candidiasis; Chitosan; Disease Models, Animal; Iran; Platelet-Rich Plasma; Rats; Rats, Wistar; Wound Healing

2020
Citryl-imine-PEG-ylated chitosan hydrogels - Promising materials for drug delivery applications.
    International journal of biological macromolecules, 2020, Nov-01, Volume: 162

    Topics: Animals; Chitosan; Diclofenac; Disease Models, Animal; Drug Delivery Systems; Hydrogels; Pain; Polyethylene Glycols; Rats

2020
Biological investigations on therapeutic effect of chitosan encapsulated nano resveratrol against gestational diabetes mellitus rats induced by streptozotocin.
    Drug delivery, 2020, Volume: 27, Issue:1

    Topics: alpha-Amylases; Animals; Blood Glucose; Chemistry, Pharmaceutical; Chitosan; Diabetes, Gestational; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Liberation; Female; Glycoside Hydrolase Inhibitors; Inflammation Mediators; Male; Nanoparticles; Particle Size; Pregnancy; Random Allocation; Rats; Rats, Inbred WF; Resveratrol; Streptozocin; Zinc Oxide

2020
Preparation of Ginkgolide Solid Dispersions with Low-Molecular-Weight Chitosan and Assessment of their Protective Effect on Isoproterenol- Induced Myocardial Injury.
    Current drug delivery, 2020, Volume: 17, Issue:8

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Cardiotonic Agents; Chitosan; Disease Models, Animal; Drug Carriers; Drug Liberation; Ginkgolides; Humans; Isoproterenol; Molecular Weight; Myocardial Infarction; Myocardium; Rats; Solubility

2020
An injectable hydrogel with pH-sensitive and self-healing properties based on 4armPEGDA and N-carboxyethyl chitosan for local treatment of hepatocellular carcinoma.
    International journal of biological macromolecules, 2020, Nov-15, Volume: 163

    Topics: 3-Mercaptopropionic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Liberation; Humans; Hydrogels; Hydrogen-Ion Concentration; Mice; Molecular Structure; Polyethylene Glycols; Xenograft Model Antitumor Assays

2020
IGF-1C hydrogel improves the therapeutic effects of MSCs on colitis in mice through PGE
    Theranostics, 2020, Volume: 10, Issue:17

    Topics: Animals; Cells, Cultured; Chitosan; Colitis, Ulcerative; Colon; Dinoprostone; Disease Models, Animal; Drug Carriers; Female; Humans; Hydrogels; Insulin-Like Growth Factor I; Intestinal Mucosa; Macrophage Activation; Macrophages, Peritoneal; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Placenta; Pregnancy; Primary Cell Culture; Trinitrobenzenesulfonic Acid

2020
Chitosan derived glycolipid nanoparticles for magnetic resonance imaging guided photodynamic therapy of cancer.
    Carbohydrate polymers, 2020, Oct-01, Volume: 245

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chitosan; Chlorophyllides; Disease Models, Animal; Drug Delivery Systems; Female; Gadolinium DTPA; Glycolipids; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Nanoparticles; Photochemotherapy; Porphyrins; Radiation-Sensitizing Agents; Stearic Acids; Tumor Burden

2020
Botulinum Toxin-Chitosan Nanoparticles Prevent Arrhythmia in Experimental Rat Models.
    Marine drugs, 2020, Aug-02, Volume: 18, Issue:8

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Botulinum Toxins, Type A; Calcium Channels; Chitosan; Disease Models, Animal; Drug Compounding; Heart Conduction System; Heart Rate; Male; Nanoparticles; Potassium Channels; Rats, Wistar; Sodium Channels

2020
Multifunctional Natural Polymer Nanoparticles as Antifibrotic Gene Carriers for CKD Therapy.
    Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:10

    Topics: Animals; Antifibrinolytic Agents; Bone Morphogenetic Protein 7; Cell Culture Techniques; Chitosan; Disease Models, Animal; Gene Transfer Techniques; Hepatocyte Growth Factor; Hyaluronic Acid; Mice; Multifunctional Nanoparticles; Polymers; Renal Insufficiency, Chronic

2020
Rapid hemostatic chitosan/cellulose composite sponge by alkali/urea method for massive haemorrhage.
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: Animals; Anti-Infective Agents; Cellulose; Chitosan; Disease Models, Animal; Escherichia coli; Hemorrhage; Hemostatics; Hydrophobic and Hydrophilic Interactions; Mice; Microbial Sensitivity Tests; Porosity; Pseudomonas aeruginosa; Rats; Staphylococcus aureus

2020
Semi-Interpenetrating Polymer Network of Hyaluronan and Chitosan Self-Healing Hydrogels for Central Nervous System Repair.
    ACS applied materials & interfaces, 2020, Sep-09, Volume: 12, Issue:36

    Topics: Animals; Biocompatible Materials; Brain Injuries, Traumatic; Cell Proliferation; Cell Survival; Cells, Cultured; Central Nervous System; Cerebral Hemorrhage; Chitosan; Disease Models, Animal; Hyaluronic Acid; Hydrogels; Male; Mice; Particle Size; Rats; Rats, Sprague-Dawley; Surface Properties; Zebrafish

2020
Silver sulfadiazine loaded breathable hydrogel sponge for wound healing.
    Drug metabolism and personalized therapy, 2020, 08-19, Volume: 35, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bandages; Chitosan; Disease Models, Animal; Fungi; Gelatin; Humans; Hydrogels; Rats; Rats, Wistar; Silver Sulfadiazine; Wound Healing

2020
Delivery of injectable thermo-sensitive hydrogel releasing nerve growth factor for spinal cord regeneration in rat animal model.
    Journal of tissue viability, 2020, Volume: 29, Issue:4

    Topics: Animals; Chitosan; Disease Models, Animal; Hydrogels; Injections; Nerve Growth Factor; Rats; Spectrophotometry, Infrared; Spinal Cord Regeneration

2020
Injectable Chitosan-Based Thermosensitive Hydrogel/Nanoparticle-Loaded System for Local Delivery of Vancomycin in the Treatment of Osteomyelitis.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Anti-Bacterial Agents; Cell Proliferation; Chitosan; Disease Models, Animal; Drug Delivery Systems; Hydrogels; Injections; Male; Nanoparticles; Osteoblasts; Osteomyelitis; Particle Size; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin

2020
The Comparative Immunotropic Activity of Carrageenan, Chitosan and Their Complexes.
    Marine drugs, 2020, Sep-04, Volume: 18, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Chitosan; Cytokines; Disease Models, Animal; Edema; Humans; Inflammation; Lymphocytes; Macrophages; Male; Mice, Inbred C57BL; Neutrophils; Phagocytosis; Polyelectrolytes

2020
Chitosan-miRNA functionalized microporous titanium oxide surfaces via a layer-by-layer approach with a sustained release profile for enhanced osteogenic activity.
    Journal of nanobiotechnology, 2020, Sep-09, Volume: 18, Issue:1

    Topics: Alkaline Phosphatase; Animals; Cell Differentiation; Cell Survival; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Female; Hyaluronic Acid; Male; Mesenchymal Stem Cells; MicroRNAs; Nanoparticles; Osseointegration; Osteogenesis; Polyelectrolytes; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Surface Properties; Titanium; Transfection

2020
    Journal of clinical orthopaedics and trauma, 2021, Volume: 12, Issue:1

    Topics: Acute Coronary Syndrome; Adolescent; Adsorption; Adult; Aged; Animals; Aspergillus; Aspergillus oryzae; Benzhydryl Compounds; Biocatalysis; Biological Availability; Biomarkers; Biomass; Brain; Brain Injuries, Traumatic; Cadmium; Calorimetry, Differential Scanning; Carbon; Carcinoma, Transitional Cell; Catalysis; Cell Death; Cells, Immobilized; Child; Child, Preschool; China; Chitosan; Creatine Kinase, MB Form; Cyclodextrins; Defibrillators, Implantable; Dendritic Spines; Diabetes Mellitus, Type 2; Diastole; Directed Molecular Evolution; Disease Models, Animal; Disease Progression; Down-Regulation; Electric Countershock; Electrolytes; Electrophoresis, Polyacrylamide Gel; Endopeptidase K; Environmental Monitoring; Esterification; Esters; Feasibility Studies; Female; Fruit; Gene Library; Glial Fibrillary Acidic Protein; Glucosides; Hippocampus; Humans; Hydrogen-Ion Concentration; Hydrolysis; Infant; Infant, Newborn; Inflammation; Ions; Kinetics; Lipase; Liver Cirrhosis; Logistic Models; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malus; Maze Learning; Melatonin; Mercury; Mice; Mice, Inbred C57BL; Middle Aged; Mining; Molecular Docking Simulation; Molecular Weight; Molybdenum; Motor Cortex; Mutagenesis, Site-Directed; Mutation; Neoplasm Recurrence, Local; Nephrectomy; Nephroureterectomy; Neurons; Oxidative Stress; Patient Discharge; Proof of Concept Study; Propionates; Prospective Studies; Protein Engineering; Protein Structure, Quaternary; Protons; PrPC Proteins; PrPSc Proteins; Rats; Rats, Wistar; Recovery of Function; Registries; Retrospective Studies; Rivers; ROC Curve; Scrapie; Sodium-Glucose Transporter 2 Inhibitors; Solubility; Solvents; Spatial Memory; Stereoisomerism; Synapses; Temperature; Time Factors; Treatment Outcome; Troponin T; Urinary Bladder Neoplasms; Urinary Tract; Ventricular Function, Left; Ventricular Remodeling; Water; Water Pollutants, Chemical; Water Purification; X-Ray Diffraction; Young Adult; Zebrafish

2021
Cholesterol (Blood lipid) lowering potential of Rosuvastatin chitosan nanoparticles for atherosclerosis: Preclinical study in rabbit model.
    Acta biochimica Polonica, 2020, Oct-22, Volume: 67, Issue:4

    Topics: Animals; Anticholesteremic Agents; Aortic Valve; Aortic Valve Stenosis; Atherosclerosis; Biomarkers; Calcinosis; Calcium; Chitosan; Cholesterol; Cholesterol, LDL; Cholic Acid; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Hypercholesterolemia; Interleukin-6; Male; Nanoparticles; Particle Size; Rabbits; Rosuvastatin Calcium; Treatment Outcome

2020
Topical Application of Virus-Derived Immunomodulating Proteins and Peptides to Promote Wound Healing in Mouse Models.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2225

    Topics: Administration, Cutaneous; Animals; Chitosan; Cicatrix; Collagen Type I; Disease Models, Animal; Drug Delivery Systems; Female; Gene Expression; Hydrogels; Immunologic Factors; Male; Mice; Mice, Inbred C57BL; Myxoma virus; Skin; Surgical Wound; Viral Proteins; Wound Healing

2021
Neurologic and Histologic Tests Used to Measure Neuroprotective Effectiveness of Virus-Derived Immune-Modulating Proteins.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2225

    Topics: Animals; Anti-Inflammatory Agents; Chitosan; Disease Models, Animal; Drug Delivery Systems; Hydrogels; Immunologic Factors; Injections, Epidural; Macrophages; Male; Motor Activity; Myxoma virus; Neuroprotective Agents; Rats; Rats, Long-Evans; Receptors, Interferon; Spinal Cord; Spinal Cord Injuries; Viral Proteins

2021
Chitosan Oligosaccharides Suppress Nuclear Factor-Kappa B Activation and Ameliorate Experimental Autoimmune Uveoretinitis in Mice.
    International journal of molecular sciences, 2020, Nov-06, Volume: 21, Issue:21

    Topics: Animals; Autoimmune Diseases; Chitosan; Disease Models, Animal; Eye Proteins; Female; Inflammation; Interleukin-17; Lymphocyte Activation; Mice; Mice, Inbred C57BL; NF-kappa B; Oligosaccharides; Retina; Retinitis; Retinol-Binding Proteins; Tumor Necrosis Factor-alpha; Uveitis

2020
Inhibition of HIF-1α/EP4 axis by hyaluronate-trimethyl chitosan-SPION nanoparticles markedly suppresses the growth and development of cancer cells.
    International journal of biological macromolecules, 2021, Jan-15, Volume: 167

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemical Phenomena; Chemistry Techniques, Synthetic; Chitosan; Dinoprostone; Disease Models, Animal; Humans; Hyaluronic Acid; Hypoxia-Inducible Factor 1, alpha Subunit; Magnetic Iron Oxide Nanoparticles; Magnetite Nanoparticles; Mice; Neoplasms; Receptors, Prostaglandin E, EP4 Subtype; RNA, Small Interfering; Signal Transduction; Spectrum Analysis

2021
Preparation of PLA/chitosan nanoscaffolds containing cod liver oil and experimental diabetic wound healing in male rats study.
    Journal of nanobiotechnology, 2020, Nov-30, Volume: 18, Issue:1

    Topics: Animals; Chitosan; Cod Liver Oil; Diabetic Foot; Disease Models, Animal; Drug Delivery Systems; Electrochemical Techniques; Male; Nanostructures; Polyesters; Rats; Wound Healing

2020
Construction of pH/glutathione responsive chitosan nanoparticles by a self-assembly/self-crosslinking method for photodynamic therapy.
    International journal of biological macromolecules, 2021, Jan-15, Volume: 167

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; Chitosan; Cross-Linking Reagents; Disease Models, Animal; Drug Stability; Glutathione; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mice; Micelles; Molecular Weight; Nanoparticles; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Xenograft Model Antitumor Assays

2021
Chitosan coated synergistically engineered nanoemulsion of Ropinirole and nigella oil in the management of Parkinson's disease: Formulation perspective and In vitro and In vivo assessment.
    International journal of biological macromolecules, 2021, Jan-15, Volume: 167

    Topics: Animals; Benzoquinones; Chitosan; Disease Models, Animal; Drug Stability; Drug Synergism; Emulsions; Female; Humans; Indoles; Male; Molecular Docking Simulation; Nanoparticles; NF-kappa B; Nigella; Oxidopamine; Parkinson Disease; Plant Oils; Rats; Tumor Necrosis Factor-alpha

2021
Chitosan oligosaccharides attenuate loperamide-induced constipation through regulation of gut microbiota in mice.
    Carbohydrate polymers, 2021, Feb-01, Volume: 253

    Topics: Animals; Antidiarrheals; Base Sequence; Bile Acids and Salts; Chitosan; Constipation; Disease Models, Animal; DNA, Ribosomal; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Gastrointestinal Motility; Intestinal Mucosa; Loperamide; Male; Mice; Mice, Inbred BALB C; Oligosaccharides; Sequence Analysis, DNA; Signal Transduction; Tryptophan

2021
Chitosan and Lecithin Ameliorate Osteoarthritis Symptoms Induced by Monoiodoacetate in a Rat Model.
    Molecules (Basel, Switzerland), 2020, Dec-04, Volume: 25, Issue:23

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Chitosan; Disease Models, Animal; Electron Transport Complex IV; Glutathione; Interleukin-6; Iodoacetic Acid; Lecithins; Male; Matrix Metalloproteinases; Osteoarthritis; Rats; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2020
Electrospun polycaprolactone (PCL)-amnion nanofibrous membrane prevents adhesions and promotes nerve repair in a rat model of sciatic nerve compression.
    PloS one, 2020, Volume: 15, Issue:12

    Topics: Amnion; Animals; Biocompatible Materials; Chitosan; Collagen; Disease Models, Animal; Hydrogels; Male; Nanofibers; Nerve Regeneration; Polyesters; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve; Sciatic Neuropathy; Tissue Adhesions; Tissue Engineering; Tissue Scaffolds

2020
Chitosan nanocarrier for FTY720 enhanced delivery retards Parkinson's disease via PP2A-EzH2 signaling in vitro and ex vivo.
    Carbohydrate polymers, 2021, Feb-15, Volume: 254

    Topics: alpha-Synuclein; Animals; Biological Availability; Cell Line, Tumor; Chitosan; Disease Models, Animal; Drug Carriers; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Fingolimod Hydrochloride; Humans; Mice; Mice, Inbred BALB C; Neurons; Neuroprotective Agents; Parkinson Disease; Phosphorylation; Protein Aggregates; Protein Phosphatase 2; Proteolysis; Signal Transduction; Sphingosine 1 Phosphate Receptor Modulators; Ubiquitination

2021
Intra-articular injection of anti-inflammatory peptide-loaded glycol chitosan/fucoidan nanogels to inhibit inflammation and attenuate osteoarthritis progression.
    International journal of biological macromolecules, 2021, Feb-15, Volume: 170

    Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Chitosan; Chondrocytes; Collagen Type II; Cytokines; Disease Models, Animal; Inflammation; Injections, Intra-Articular; Interleukin-1beta; Interleukin-6; Male; Nanogels; Osteoarthritis; Polysaccharides; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2021
Chitosan and gelatin biopolymer supplemented with mesenchymal stem cells (Velgraft®) enhanced wound healing in goats (Capra hircus): Involvement of VEGF, TGF and CD31.
    Journal of tissue viability, 2021, Volume: 30, Issue:1

    Topics: Analysis of Variance; Animals; Biopolymers; Chitosan; Disease Models, Animal; Gelatin; Goats; Male; Mesenchymal Stem Cells; Platelet Endothelial Cell Adhesion Molecule-1; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Wound Healing

2021
Antibacterial Effects of Orthodontic Primer Harboring Chitosan Nanoparticles against the Multispecies Biofilm of Cariogenic Bacteria in a Rat Model.
    Folia medica, 2020, Dec-31, Volume: 62, Issue:4

    Topics: Animals; Bacteria; Bacterial Infections; Biofilms; Chitosan; Disease Models, Animal; Nanoparticles; Orthodontic Brackets; Rats; Rats, Wistar; Saliva

2020
In-vivo wound healing activity of a novel composite sponge loaded with mucilage and lipoidal matter of Hibiscus species.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 135

    Topics: Administration, Cutaneous; Animals; Cell Line; Chitosan; Disease Models, Animal; Hibiscus; Humans; Inflammation Mediators; Lipids; Male; Plant Extracts; Rats, Wistar; Re-Epithelialization; Skin; Surgical Sponges; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Wound Healing; Wounds, Penetrating

2021
Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Abdomen; Animals; Cecum; Chitosan; Deferiprone; Disease Models, Animal; Enterostomy; Gels; Kaolin; Protoporphyrins; Rats; Rats, Wistar; Tensile Strength; Tissue Adhesions

2021
The role of Chito-oligosaccharide in regulating ovarian germ stem cells function and restoring ovarian function in chemotherapy mice.
    Reproductive biology and endocrinology : RB&E, 2021, Jan-25, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chitosan; Disease Models, Animal; Female; Germ Cells; Mice; Oligosaccharides; Ovarian Follicle; Ovary; Primary Ovarian Insufficiency; Recovery of Function; Stem Cells

2021
Evaluation of wound healing efficiency of vancomycin-loaded electrospun chitosan/poly ethylene oxide nanofibers in full thickness wound model of rat.
    International journal of biological macromolecules, 2021, Apr-30, Volume: 177

    Topics: Animals; Anti-Bacterial Agents; Bandages; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Liberation; Ethylene Oxide; Fibroblasts; Male; Nanofibers; Polyethylene Glycols; Rats; Rats, Wistar; Vancomycin; Wound Healing

2021
Alginate-chitosan microcapsules improve vaccine potential of gamma-irradiated Listeria monocytogenes against listeriosis in murine model.
    International journal of biological macromolecules, 2021, Apr-15, Volume: 176

    Topics: Alginates; Animals; Bacterial Vaccines; Chitosan; Disease Models, Animal; Female; Gamma Rays; Listeria monocytogenes; Listeriosis; Mice; Mice, Inbred BALB C; Vaccines, Inactivated

2021
Development of a chitosan-modified PLGA nanoparticle vaccine for protection against Escherichia coli K1 caused meningitis in mice.
    Journal of nanobiotechnology, 2021, Mar-05, Volume: 19, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Chitosan; Disease Models, Animal; Drug Delivery Systems; Escherichia coli; Escherichia coli Infections; Female; Immunity; Meningitis; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Recombinant Proteins; Vaccines

2021
Development of a dual delivery of levofloxacin and prednisolone acetate via PLGA nanoparticles/ thermosensitive chitosan-based hydrogel for postoperative management: An in-vitro and ex-vivo study.
    International journal of biological macromolecules, 2021, Jun-01, Volume: 180

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Chitosan; Cytokines; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug Therapy, Combination; Endophthalmitis; Epithelial Cells; Epithelium, Corneal; Hydrogels; Keratitis; Levofloxacin; Nanoparticles; Particle Size; Postoperative Complications; Prednisolone; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Temperature

2021
Emulsion-free chitosan-genipin microgels for growth plate cartilage regeneration.
    Journal of biomaterials applications, 2021, Volume: 36, Issue:2

    Topics: Animals; Biocompatible Materials; Cartilage; Chitosan; Disease Models, Animal; Emulsions; Iridoids; Male; Microgels; Rats; Rats, Sprague-Dawley; Regeneration; Salter-Harris Fractures

2021
Visible light-curable water-soluble chitosan derivative, chitosan hydrogel, and preparation method: a patent evaluation of US2019202998A1.
    Expert opinion on therapeutic patents, 2021, Volume: 31, Issue:5

    Topics: Animals; Bioprinting; Chitosan; Cross-Linking Reagents; Disease Models, Animal; Humans; Hydrogels; Light; Mice; Patents as Topic; Polymers; Wound Healing

2021
Research on Preparation of 5-ASA Colon-Specific Hydrogel Delivery System without Crosslinking Agent by Mechanochemical Method.
    Pharmaceutical research, 2021, Volume: 38, Issue:4

    Topics: Administration, Oral; Alginates; Animals; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Hydrogels; Hydrogen-Ion Concentration; Intestinal Mucosa; Male; Mesalamine; Mice; Particle Size; Rats

2021
Development and
    BioMed research international, 2020, Volume: 2020

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Drug Compounding; Limosilactobacillus fermentum; Nanogels; Probiotics; Rats, Sprague-Dawley; Skin; Spectroscopy, Fourier Transform Infrared; Wound Healing

2020
Exploring Effects of Chitosan Oligosaccharides on the DSS-Induced Intestinal Barrier Impairment In Vitro and In Vivo.
    Molecules (Basel, Switzerland), 2021, Apr-11, Volume: 26, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Caco-2 Cells; Chitosan; Colitis; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation; HT29 Cells; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mucin-2; Occludin; Oligosaccharides; Permeability; Signal Transduction; Survival Analysis; Tight Junctions

2021
The biological synthesis of gold/perlite nanocomposite using Urtica dioica extract and its chitosan-capped derivative for healing wounds infected with methicillin-resistant Staphylococcus aureus.
    International journal of biological macromolecules, 2021, Jul-31, Volume: 183

    Topics: Aluminum Oxide; Animals; Anti-Bacterial Agents; Antioxidants; Cell Proliferation; Chitosan; Disease Models, Animal; Drug Compounding; Fibroblasts; Gold Compounds; Green Chemistry Technology; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Nanoparticles; Nanotechnology; NIH 3T3 Cells; Signal Transduction; Silicon Dioxide; Skin; Staphylococcal Skin Infections; Time Factors; Urtica dioica; Wound Healing

2021
Effects of chitosan and platelet-rich plasma on facial nerve regeneration in an animal model.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022, Volume: 279, Issue:2

    Topics: Animals; Chitosan; Disease Models, Animal; Facial Nerve; Nerve Regeneration; Platelet-Rich Plasma; Rats

2022
Novel glaucoma model in rats using photo-crosslinked azidobenzoic acid-modified chitosan.
    Materials science & engineering. C, Materials for biological applications, 2021, Volume: 125

    Topics: Animals; Chitosan; Disease Models, Animal; Glaucoma; Intraocular Pressure; Rats; Retinal Ganglion Cells

2021
Endoscopic application of mussel-inspired phenolic chitosan as a hemostatic agent for gastrointestinal bleeding: A preclinical study in a heparinized pig model.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Animals; Anticoagulants; Bivalvia; Catechols; Chitosan; Disease Models, Animal; Drug Evaluation, Preclinical; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Hemostatics; Heparin; Male; Swine

2021
Long-term pre-clinical evaluation of an injectable chitosan nanocellulose hydrogel with encapsulated adipose-derived stem cells in an ovine model for IVD regeneration.
    Journal of tissue engineering and regenerative medicine, 2021, Volume: 15, Issue:7

    Topics: Adipose Tissue; Animals; Cells, Immobilized; Cellulose; Chitosan; Disease Models, Animal; Hydrogels; Injections; Intervertebral Disc Degeneration; Nanoparticles; Sheep; Stem Cells

2021
An efficient enzyme-triggered controlled release system for colon-targeted oral delivery to combat dextran sodium sulfate (DSS)-induced colitis in mice.
    Drug delivery, 2021, Volume: 28, Issue:1

    Topics: Administration, Oral; Alginates; Animals; beta-Cyclodextrins; Chemistry, Pharmaceutical; Chitosan; Colitis; Curcumin; Cytokines; Delayed-Action Preparations; Dextran Sulfate; Disease Models, Animal; Drug Carriers; Drug Liberation; Hydrogen-Ion Concentration; Macrophages; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Particle Size

2021
Studies on novel chitosan/alginate and chitosan/bentonite flexible films incorporated with ZnO nano particles for accelerating dermal burn healing: In vivo and in vitro evaluation.
    International journal of biological macromolecules, 2021, Aug-01, Volume: 184

    Topics: Alginates; Animals; Anti-Bacterial Agents; Bentonite; Cell Line; Chitosan; Disease Models, Animal; Female; Mice; Microbial Sensitivity Tests; Nanoparticles; Pseudomonas aeruginosa; Rats; Re-Epithelialization; Staphylococcus aureus; Wound Healing; Zinc Oxide

2021
Self-assembled chitosan nanoparticles for intranasal delivery of recombinant protein interleukin-17 receptor C (IL-17RC): preparation and evaluation in asthma mice.
    Bioengineered, 2021, Volume: 12, Issue:1

    Topics: Administration, Intranasal; Animals; Asthma; Chitosan; Cytokines; Disease Models, Animal; Female; Lung; Mice; Mice, Inbred BALB C; Nanoparticles; Receptors, Interleukin-17; Recombinant Proteins

2021
Copper metal-organic framework embedded carboxymethyl chitosan-g-glutathione/polyacrylamide hydrogels for killing bacteria and promoting wound healing.
    International journal of biological macromolecules, 2021, Sep-30, Volume: 187

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Chitosan; Copper; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Escherichia coli; Hydrogels; Male; Metal-Organic Frameworks; Oxidative Stress; Rats, Sprague-Dawley; Skin; Staphylococcus aureus; Wound Healing; Wounds and Injuries

2021
Influence of Dietary Chitosan Feeding Duration on Glucose and Lipid Metabolism in a Diabetic Rat Model.
    Molecules (Basel, Switzerland), 2021, Aug-19, Volume: 26, Issue:16

    Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Disease Models, Animal; Glucose; Lipid Metabolism; Male; Rats; Rats, Sprague-Dawley; Time Factors

2021
Poly-γ-glutamic acid/chitosan nanogel greatly enhances the efficacy and heterosubtypic cross-reactivity of H1N1 pandemic influenza vaccine.
    Scientific reports, 2017, 03-21, Volume: 7

    Topics: Adjuvants, Immunologic; Animals; Antigen Presentation; Antigens, Viral; Chitosan; Cross Reactions; Dendritic Cells; Disease Models, Animal; Ferrets; Histocompatibility Antigens Class I; Humans; Immunity, Cellular; Immunogenicity, Vaccine; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Mice; Orthomyxoviridae Infections; Phagosomes; Polyglutamic Acid

2017
Nerve transection repair using laser-activated chitosan in a rat model.
    The Laryngoscope, 2017, Volume: 127, Issue:8

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Male; Microsurgery; Neurosurgical Procedures; Peripheral Nerve Injuries; Pilot Projects; Rats; Rats, Sprague-Dawley; Suture Techniques; Tensile Strength

2017
Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin.
    Biomaterials, 2017, Volume: 130

    Topics: Administration, Oral; Animals; Biological Transport; Blood Glucose; Caco-2 Cells; Chitosan; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Delivery Systems; Electric Impedance; Freeze Drying; Humans; Hydrogen-Ion Concentration; Insulin; Male; Nanoparticles; Particle Size; Polyphosphates; Rats, Sprague-Dawley; Sus scrofa; Tight Junctions

2017
Artemisinin loaded chitosan magnetic nanoparticles for the efficient targeting to the breast cancer.
    International journal of biological macromolecules, 2017, Volume: 104, Issue:Pt B

    Topics: Animals; Antineoplastic Agents; Artemisinins; Breast Neoplasms; Cell Line, Tumor; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Female; Humans; Magnetite Nanoparticles; Mice; Particle Size; Spectroscopy, Fourier Transform Infrared; Xenograft Model Antitumor Assays

2017
Reduction of Abdominal Adhesions with Elecrospun Fiber Membranes in Rat Models.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2018, Volume: 31, Issue:3

    Topics: Animals; Cecum; Chitosan; Disease Models, Animal; Fibrosis; Humans; Hydroxybutyrates; Hydroxyproline; Incidence; Laparotomy; Male; Membranes, Artificial; Polyesters; Polyethylene Glycols; Postoperative Complications; Rats; Rats, Sprague-Dawley; Tissue Adhesions

2018
The amelioration of cartilage degeneration by photo-crosslinked GelHA hydrogel and crizotinib encapsulated chitosan microspheres.
    Oncotarget, 2017, May-02, Volume: 8, Issue:18

    Topics: Animals; Biomarkers; Cartilage; Chitosan; Chondrocytes; Crizotinib; Disease Models, Animal; Drug Carriers; Drug Liberation; Gene Expression; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Interleukin-1beta; Mice; Microspheres; Neovascularization, Pathologic; Osteoarthritis; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Vascular Endothelial Growth Factor A

2017
Effectiveness of tissue engineered based platelet gel embedded chitosan scaffold on experimentally induced critical sized segmental bone defect model in rat.
    Injury, 2017, Volume: 48, Issue:7

    Topics: Animals; Biocompatible Materials; Blood Platelets; Bone Regeneration; Chitosan; Disease Models, Animal; Gels; Male; Plastic Surgery Procedures; Radius Fractures; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Engineering; Tissue Scaffolds; Wound Healing

2017
Bioengineered keratocyte spheroids fabricated on chitosan coatings enhance tissue repair in a rabbit corneal stromal defect model.
    Journal of tissue engineering and regenerative medicine, 2018, Volume: 12, Issue:2

    Topics: Animals; Bioengineering; Chitosan; Coated Materials, Biocompatible; Corneal Keratocytes; Corneal Stroma; Disease Models, Animal; Rabbits; Regeneration; Spheroids, Cellular

2018
Chitosan stabilized camptothecin nanoemulsions: Development, evaluation and biodistribution in preclinical breast cancer animal mode.
    International journal of biological macromolecules, 2017, Volume: 104, Issue:Pt B

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Survival; Chitosan; Disease Models, Animal; Drug Carriers; Drug Evaluation, Preclinical; Drug Liberation; Drug Stability; Emulsions; Female; Humans; MCF-7 Cells; Mice; Nanoparticles; Tissue Distribution; Xenograft Model Antitumor Assays

2017
The preventive effect of ambroxol hydrochloride chitosan on postoperative intraperitoneal adhesion formation in a rat model.
    Acta chirurgica Belgica, 2017, Volume: 117, Issue:4

    Topics: Ambroxol; Animals; Chitosan; Disease Models, Animal; Expectorants; Hemostatics; Intestines; Peritoneum; Rats; Rats, Sprague-Dawley; Tissue Adhesions

2017
Mouse IP-10 Gene Delivered by Folate-modified Chitosan Nanoparticles and Dendritic/tumor Cells Fusion Vaccine Effectively Inhibit the Growth of Hepatocellular Carcinoma in Mice.
    Theranostics, 2017, Volume: 7, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chemokine CXCL10; Chitosan; Dendritic Cells; Disease Models, Animal; Drug Carriers; Folic Acid; Heterografts; Mice; Mice, Inbred C57BL; Nanoparticles; Treatment Outcome; Vaccines, DNA

2017
The effects of chitosan oligosaccharides on OPG and RANKL expression in a rat osteoarthritis model.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:6

    Topics: Animals; Cartilage, Articular; Chitosan; Disease Models, Animal; Gene Expression Regulation; Male; Oligosaccharides; Osteoarthritis; Osteoprotegerin; RANK Ligand; Rats; Rats, Sprague-Dawley

2017
Chitosan-Fe (III) Complex as a Phosphate Chelator in Uraemic Rats: A Novel Treatment Option.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:1

    Topics: Adenine; Animals; Chelating Agents; Chitosan; Creatinine; Disease Models, Animal; Ferric Compounds; Humans; Hyperphosphatemia; Phosphates; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Uremia

2018
Translation of an injectable triple-interpenetrating-network hydrogel for intervertebral disc regeneration in a goat model.
    Acta biomaterialia, 2017, 09-15, Volume: 60

    Topics: Animals; Chitosan; Dextrans; Disease Models, Animal; Goats; Hydrogels; Intervertebral Disc Degeneration; Lumbar Vertebrae; Regeneration

2017
A PEGylated fibrin hydrogel-based antimicrobial wound dressing controls infection without impeding wound healing.
    International wound journal, 2017, Volume: 14, Issue:6

    Topics: Animals; Anti-Infective Agents, Local; Bandages, Hydrocolloid; Chitosan; Disease Models, Animal; Fibrin; Microspheres; Pseudomonas Infections; Silver Sulfadiazine; Swine; Wound Healing; Wounds and Injuries

2017
Modulation of periodontitis progression using pH-responsive nanosphere encapsulating metronidazole or N-phenacylthialzolium bromide.
    Journal of periodontal research, 2018, Volume: 53, Issue:1

    Topics: Animals; Anti-Infective Agents; Chitosan; Disease Models, Animal; Disease Progression; Lactic Acid; Metronidazole; Nanospheres; Periodontitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles

2018
Intranasal administration of brain-targeted HP-β-CD/chitosan nanoparticles for delivery of scutellarin, a compound with protective effect in cerebral ischaemia.
    The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:11

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Intranasal; Animals; Apigenin; Biological Availability; Brain; Brain Ischemia; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Glucuronates; Half-Life; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Solubility; Tissue Distribution

2017
Inhibition of Growth of Candida albicans by a Lysozyme-chitosan Conjugate, LYZOX and its Combination with Decanoic Acid.
    Medical mycology journal, 2017, Volume: 58, Issue:3

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis, Oral; Chitosan; Decanoic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Fungal; Drug Synergism; Drug Therapy, Combination; Mice, Inbred ICR; Muramidase; Treatment Outcome

2017
Peptide-Modified Chitosan Hydrogels Accelerate Skin Wound Healing by Promoting Fibroblast Proliferation, Migration, and Secretion.
    Cell transplantation, 2017, Volume: 26, Issue:8

    Topics: Animals; Cell Movement; Cell Proliferation; Chitosan; Disease Models, Animal; Female; Fibroblasts; Hydrogels; Mice; Mice, Inbred C57BL; Skin; Wound Healing

2017
Piperine-loaded chitosan-STPP nanoparticles reduce neuronal loss and astrocytes activation in chemical kindling model of epilepsy.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt A

    Topics: Alkaloids; Animals; Astrocytes; Benzodioxoles; Chitosan; Disease Models, Animal; Epilepsy; Humans; Hydrophobic and Hydrophilic Interactions; Kindling, Neurologic; Mice; Nanoparticles; Neurons; Organophosphorus Compounds; Pentylenetetrazole; Piperidines; Polyunsaturated Alkamides; Stearic Acids

2018
Effect of Tendon Stem Cells in Chitosan/β-Glycerophosphate/Collagen Hydrogel on Achilles Tendon Healing in a Rat Model.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Sep-27, Volume: 23

    Topics: Achilles Tendon; Animals; Biomechanical Phenomena; Cell Differentiation; Cell Shape; Chitosan; Collagen; Disease Models, Animal; Glycerophosphates; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogen-Ion Concentration; Immunohistochemistry; Male; Rats, Sprague-Dawley; Stem Cells; Time Factors; Wound Healing

2017
Oral Delivery of Nanoparticles Loaded With Ginger Active Compound, 6-Shogaol, Attenuates Ulcerative Colitis and Promotes Wound Healing in a Murine Model of Ulcerative Colitis.
    Journal of Crohn's & colitis, 2018, Jan-24, Volume: 12, Issue:2

    Topics: Alginates; Animals; Biocompatible Materials; Catechols; Cell Line; Chitosan; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Drug Delivery Systems; Epithelial Cells; Folic Acid; Glucuronic Acid; Heme Oxygenase-1; Hexuronic Acids; Hydrogels; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Macrophages; Membrane Proteins; Mice; Nanoparticles; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Polyethylene Glycols; RNA, Messenger; Tumor Necrosis Factor-alpha; Wound Healing

2018
Enhanced antitumor efficacy of arginine modified amphiphilic nanoparticles co-delivering doxorubicin and iSur-pDNA via the multiple synergistic effect.
    Biomaterials, 2018, Volume: 150

    Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Apoptosis; Arginine; Cell Line, Tumor; Cell Proliferation; Chitosan; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Drug Synergism; Female; Humans; Inhibitor of Apoptosis Proteins; Mice; Nanoparticles; RNA, Small Interfering; Surface-Active Agents; Survivin

2018
Development and evaluation of novel biodegradable chitosan based metformin intrapocket dental film for the management of periodontitis and alveolar bone loss in a rat model.
    Archives of oral biology, 2018, Volume: 85

    Topics: Alveolar Bone Loss; Animals; Anti-Bacterial Agents; Chitosan; Disease Models, Animal; Drug Implants; Male; Materials Testing; Metformin; Microscopy, Electron, Scanning; Periodontitis; Porphyromonas gingivalis; Rats; Rats, Wistar; Surface Properties; X-Ray Diffraction

2018
Chitinase Induction Prior to Caspofungin Treatment of Experimental Invasive Aspergillosis in Neutropenic Rats Does Not Enhance Survival.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:1

    Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Caspofungin; Chitinases; Chitosan; Disease Models, Animal; Female; Invasive Pulmonary Aspergillosis; Lung; Microbial Sensitivity Tests; Molecular Weight; Neutropenia; Rats

2018
Intranasal Vaccination with Mannosylated Chitosan Formulated DNA Vaccine Enables Robust IgA and Cellular Response Induction in the Lungs of Mice and Improves Protection against Pulmonary Mycobacterial Challenge.
    Frontiers in cellular and infection microbiology, 2017, Volume: 7

    Topics: Administration, Intranasal; Animals; BCG Vaccine; Bronchoalveolar Lavage Fluid; Chitosan; Cytokines; Disease Models, Animal; Epitopes, T-Lymphocyte; Female; Immunity, Cellular; Immunoglobulin A; Mannose; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Mycobacterium tuberculosis; Nanoparticles; Pulmonary Alveoli; Tuberculosis Vaccines; Tuberculosis, Pulmonary; Vaccination; Vaccines, DNA

2017
Osseointegration of layer-by-layer polyelectrolyte multilayers loaded with IGF1 and coated on titanium implant under osteoporotic condition.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Animals; Bone Marrow Cells; Bone-Implant Interface; Chitosan; Coated Materials, Biocompatible; Dental Materials; Disease Models, Animal; Female; Insulin-Like Growth Factor I; Mesenchymal Stem Cells; Osseointegration; Osteoporosis; Polyelectrolytes; Prostheses and Implants; Rats, Sprague-Dawley; Titanium

2017
Chitosan-film associated with mesenchymal stem cells enhanced regeneration of peripheral nerves: A rat sciatic nerve model.
    Journal of chemical neuroanatomy, 2018, Volume: 88

    Topics: Animals; Chitosan; Disease Models, Animal; Guided Tissue Regeneration; Humans; Male; Mesenchymal Stem Cell Transplantation; Nerve Regeneration; Peripheral Nerve Injuries; Rats; Rats, Wistar; Sciatic Nerve; Tissue Scaffolds

2018
Biocompatible chitosan based hydrogels for potential application in local tumour therapy.
    Carbohydrate polymers, 2018, Jan-01, Volume: 179

    Topics: Animals; Antineoplastic Agents; Benzaldehydes; Biocompatible Materials; Capillary Action; Cell Survival; Chitosan; Disease Models, Animal; Elasticity; Granuloma, Foreign-Body; HeLa Cells; Humans; Hydrogels; Polyamines; Rats; Shear Strength; Viscosity

2018
Schwann cells and mesenchymal stem cells in laminin- or fibronectin-aligned matrices and regeneration across a critical size defect of 15 mm in the rat sciatic nerve.
    Journal of neurosurgery. Spine, 2018, Volume: 28, Issue:1

    Topics: Animals; Chitosan; Disease Models, Animal; Extracellular Matrix; Female; Fibronectins; Laminin; Mesenchymal Stem Cells; Nerve Regeneration; Peripheral Nerve Injuries; Rats; Rats, Wistar; Schwann Cells; Sciatic Nerve; Tissue Scaffolds

2018
Chitosan-Graphene Oxide 3D scaffolds as Promising Tools for Bone Regeneration in Critical-Size Mouse Calvarial Defects.
    Scientific reports, 2017, 11-30, Volume: 7, Issue:1

    Topics: Alkaline Phosphatase; Animals; Biomarkers; Biopsy; Bone Regeneration; Chitosan; Disease Models, Animal; Graphite; Immunohistochemistry; Mice; Osteogenesis; Oxides; Printing, Three-Dimensional; Skull; Tissue Scaffolds

2017
Single dose HBsAg CS-γ-PGA nanogels induce potent protective immune responses against HBV infection.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 124

    Topics: Adjuvants, Immunologic; Animals; Chitosan; Dendritic Cells; Disease Models, Animal; Drug Carriers; Drug Compounding; Gels; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Immunity, Cellular; Immunity, Humoral; Immunization; Immunogenicity, Vaccine; Immunologic Memory; Male; Mice, Inbred C57BL; Nanomedicine; Nanoparticles; Polyglutamic Acid; T-Lymphocyte Subsets; Technology, Pharmaceutical; Time Factors

2018
Pramipexole dihydrochloride loaded chitosan nanoparticles for nose to brain delivery: Development, characterization and in vivo anti-Parkinson activity.
    International journal of biological macromolecules, 2018, Apr-01, Volume: 109

    Topics: Administration, Intranasal; Animals; Antiparkinson Agents; Benzothiazoles; Biomarkers; Blood-Brain Barrier; Chitosan; Disease Models, Animal; Dopamine; Drug Carriers; Drug Delivery Systems; Locomotion; Male; Nanoparticles; Parkinson Disease; Particle Size; Pramipexole; Rats; Reactive Oxygen Species; Tissue Distribution

2018
Optimization of Transforming Growth Factor-β1 siRNA Loaded Chitosan-Tripolyphosphate Nanoparticles for the Treatment of Colorectal Cancer Hepatic Metastasis in a Mouse Model.
    Journal of biomedical nanotechnology, 2016, Volume: 12, Issue:7

    Topics: Animals; Chitosan; Colorectal Neoplasms; Disease Models, Animal; Drug Carriers; Liver; Liver Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; RNA Interference; RNA, Small Interfering; Transforming Growth Factor beta1

2016
Immune protective effects of chitooligosaccharides on mice genital tract infected by Chlamydia trachomatis.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2018, Volume: 79, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Bacterial Load; Chitin; Chitosan; Chlamydia Infections; Chlamydia trachomatis; Disease Models, Animal; Female; Genitalia; HeLa Cells; Humans; Immunoglobulin G; Interleukin-11; Mice; Mice, Inbred BALB C; Oligosaccharides; Th1 Cells

2018
Development, characterization, and in vitro-in vivo evaluation of polymeric nanoparticles containing miconazole and farnesol for treatment of vulvovaginal candidiasis.
    Medical mycology, 2019, Jan-01, Volume: 57, Issue:1

    Topics: Animals; Antifungal Agents; BALB 3T3 Cells; Candida albicans; Candidiasis, Vulvovaginal; Capsules; Chitosan; Disease Models, Animal; Farnesol; Female; Mice; Mice, Inbred BALB C; Miconazole; Microbial Sensitivity Tests; Microbial Viability; Nanoparticles

2019
Improvement of Diet-induced Obesity by Ingestion of Mushroom Chitosan Prepared from Flammulina velutipes.
    Journal of oleo science, 2018, Feb-01, Volume: 67, Issue:2

    Topics: Adipocytes; Administration, Oral; Animals; Anti-Obesity Agents; Chitosan; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Flammulina; Lipolysis; Male; Mice, Inbred ICR; Non-alcoholic Fatty Liver Disease; Obesity; Phytotherapy; Weight Gain

2018
Regenerative potential of chitosan-coated poly-3-hydroxybutyrate conduits seeded with mesenchymal stem cells in a rat sciatic nerve injury model.
    The International journal of neuroscience, 2018, Volume: 128, Issue:9

    Topics: Analysis of Variance; Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Electromyography; Evoked Potentials, Motor; Hydroxybutyrates; Male; Mesenchymal Stem Cells; Nerve Regeneration; Polyesters; Prohibitins; Rats; Rats, Wistar; Sciatic Neuropathy; Walking

2018
In vitro and in vivo investigation of a novel amniotic-based chitosan dressing for wound healing.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2018, Volume: 26, Issue:1

    Topics: Amnion; Animals; Biological Dressings; Biopsy, Needle; Burns; Chitosan; Cicatrix; Disease Models, Animal; Humans; Immunohistochemistry; In Vitro Techniques; Male; Neovascularization, Physiologic; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Wound Healing

2018
Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs.
    Molecular pharmacology, 2018, Volume: 93, Issue:5

    Topics: Acyltransferases; Administration, Oral; Animals; Blindness; Chitosan; Cone Opsins; Disease Models, Animal; Diterpenes; Dogs; Dose-Response Relationship, Drug; Electroretinography; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Opsins; Photoreceptor Cells, Vertebrate; Retinal Pigment Epithelium; Retinaldehyde; Rod Opsins; Tomography, Optical Coherence

2018
Chitosan-Based Hydrogel Microparticles for Treatment of Carcinoma in a Rabbit VX2 Liver Tumor Model.
    Journal of vascular and interventional radiology : JVIR, 2018, Volume: 29, Issue:4

    Topics: Angiography; Animals; Chitosan; Contrast Media; Disease Models, Animal; Embolization, Therapeutic; Hydrogels; Liver Function Tests; Liver Neoplasms, Experimental; Rabbits; Tomography, X-Ray Computed; Tumor Burden

2018
'In Vitro', 'In Vivo' and 'In Silico' Investigation of the Anticancer Effectiveness of Oxygen-Loaded Chitosan-Shelled Nanodroplets as Potential Drug Vector.
    Pharmaceutical research, 2018, Feb-26, Volume: 35, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Carcinoma In Situ; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chitosan; Computer Simulation; Disease Models, Animal; Drug Compounding; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Fluorocarbons; Humans; Mice; Mice, Inbred BALB C; Models, Biological; Nanoparticles; Oxygen

2018
Long-Term Implantability of Resorbable Carboxymethyl Cellulose/Chitosan Microspheres in a Rabbit Renal Arterial Embolization Model.
    Cardiovascular and interventional radiology, 2018, Volume: 41, Issue:6

    Topics: Angiography; Animals; Chitosan; Disease Models, Animal; Embolization, Therapeutic; Female; Microspheres; Rabbits; Renal Artery; Time

2018
Anti-inflammatory effects in a mouse osteoarthritis model of a mixture of glucosamine and chitooligosaccharides produced by bi-enzyme single-step hydrolysis.
    Scientific reports, 2018, 04-04, Volume: 8, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chitin; Chitosan; Disease Models, Animal; Glucosamine; Glycoside Hydrolases; Hexosaminidases; Hydrolysis; Male; Mice; Mice, Inbred C57BL; Oligosaccharides; Osteoarthritis

2018
Nasal vaccination with r4M2e.HSP70c antigen encapsulated into N-trimethyl chitosan (TMC) nanoparticulate systems: Preparation and immunogenicity in a mouse model.
    Vaccine, 2018, 05-11, Volume: 36, Issue:20

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Viral; Bronchoalveolar Lavage Fluid; Cell Proliferation; Chitosan; Disease Models, Animal; Drug Carriers; Female; HSP72 Heat-Shock Proteins; Humans; Immunity, Cellular; Immunity, Humoral; Immunoglobulin A; Immunoglobulin G; Influenza Vaccines; Influenza, Human; Interferon-gamma; Leukocytes, Mononuclear; Mice, Inbred BALB C; Nanoparticles; Serum; Survival Analysis; Treatment Outcome; Vaccines, Synthetic; Viral Matrix Proteins

2018
Local Delivery of Amikacin and Vancomycin from Chitosan Sponges Prevent Polymicrobial Implant-Associated Biofilm.
    Military medicine, 2018, 03-01, Volume: 183, Issue:suppl_1

    Topics: Amikacin; Animals; Anti-Bacterial Agents; Biofilms; Chitosan; Coinfection; Disease Models, Animal; Mice; Microbial Sensitivity Tests; Vancomycin

2018
Quantification and Brain Targeting of Eugenol-Loaded Surface Modified Nanoparticles Through Intranasal Route in the Treatment of Cerebral Ischemia.
    Drug research, 2018, Volume: 68, Issue:10

    Topics: Administration, Intranasal; Animals; Biological Availability; Blood-Brain Barrier; Brain Ischemia; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Emulsifying Agents; Eugenol; Goats; Humans; Male; Nanoparticles; Nasal Mucosa; Neuroprotective Agents; Permeability; Rats; Rats, Wistar; Surface Properties; Tissue Distribution; Toxicity Tests; Treatment Outcome

2018
A self-destructive nanosweeper that captures and clears amyloid β-peptides.
    Nature communications, 2018, 05-04, Volume: 9, Issue:1

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Autophagy; Beclin-1; Brain; Cell Line, Tumor; Chitosan; Disease Models, Animal; Humans; Maze Learning; Mice, Inbred C57BL; Mice, Transgenic; Nanoparticles; Peptides; Plaque, Amyloid; Polyethylene Glycols

2018
Chitosan-coated C-phycocyanin Liposome for Extending the Neuroprotective Time Window Against Ischemic Brain Stroke.
    Current pharmaceutical design, 2018, Volume: 24, Issue:17

    Topics: Animals; Chitosan; Disease Models, Animal; Infarction, Middle Cerebral Artery; Liposomes; Neuroprotective Agents; Phycocyanin; Rats; Stroke

2018
Thermoresponsive polysaccharide-based composite hydrogel with antibacterial and healing-promoting activities for preventing recurrent adhesion after adhesiolysis.
    Acta biomaterialia, 2018, 07-01, Volume: 74

    Topics: Animals; Anti-Bacterial Agents; Chitosan; Disease Models, Animal; Glucans; Hydrogels; Materials Testing; Mice; Rabbits; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Xylans

2018
Chitosan Microsphere Used as an Effective System to Deliver a Linked Antigenic Peptides Vaccine Protect Mice Against Acute and Chronic
    Frontiers in cellular and infection microbiology, 2018, Volume: 8

    Topics: Animals; Antibodies, Protozoan; Chitosan; Disease Models, Animal; Epitopes, B-Lymphocyte; Epitopes, T-Lymphocyte; Female; Humans; Immunity, Cellular; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microspheres; Protozoan Proteins; Protozoan Vaccines; Toxoplasma; Toxoplasmosis, Animal

2018
Effect of insulin-coated trimethyl chitosan nanoparticles on IGF-1, IGF-2, and apoptosis in the hippocampus of diabetic male rats.
    Restorative neurology and neuroscience, 2018, Volume: 36, Issue:4

    Topics: Animals; Anticholesteremic Agents; Apoptosis; Chitosan; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Delivery Systems; Hippocampus; Hypoglycemic Agents; In Situ Nick-End Labeling; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Nanoparticles; Rats; Rats, Wistar

2018
Chondroprotective Effects of Hyaluronic Acid-Chitosan Nanoparticles Containing Plasmid DNA Encoding Cytokine Response Modifier A in a Rat Knee Osteoarthritis Model.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:3

    Topics: Animals; Chitosan; Cytokines; Disease Models, Animal; Hyaluronic Acid; Nanoparticles; Osteoarthritis, Knee; Plasmids; Rats; Serpins; Viral Proteins

2018
Novel hydrogel-based ocular drug delivery system for the treatment of conjunctivitis.
    International ophthalmology, 2019, Volume: 39, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Betamethasone; Biological Availability; Chitosan; Conjunctivitis; Disease Models, Animal; Drug Delivery Systems; Eye Infections; Glucocorticoids; Hydrogels; Neomycin; Poloxamer; Rabbits

2019
Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation.
    Drug delivery and translational research, 2018, Volume: 8, Issue:5

    Topics: Animals; Arthrocentesis; Biomarkers; Calcitonin; Chitosan; Disease Models, Animal; Drug Carriers; Horses; Hyaluronic Acid; Injections, Intra-Articular; Lipopolysaccharides; Nanoconjugates; Pilot Projects; Synovial Fluid; Synovitis

2018
The Use of Chitosan-Coated Membrane Vesicles for Immunization Against Salmonid Rickettsial Septicemia in an Adult Zebrafish Model.
    Zebrafish, 2018, Volume: 15, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Bacterial Vaccines; Chitosan; Cytoplasmic Vesicles; Disease Models, Animal; Fish Diseases; Fish Proteins; Gene Expression Regulation; Immunity, Innate; Immunization; Piscirickettsia; Piscirickettsiaceae Infections; Sepsis; Zebrafish

2018
Quetiapine protects the blood-brain barrier in traumatic brain injury.
    The journal of trauma and acute care surgery, 2018, Volume: 85, Issue:5

    Topics: Animals; Antipsychotic Agents; beta Catenin; Blood-Brain Barrier; Brain; Brain Injuries, Traumatic; Cells, Cultured; Chitosan; Computer Simulation; Disease Models, Animal; Electric Impedance; Endothelial Cells; Humans; Intravital Microscopy; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Microvessels; Models, Molecular; Permeability; Quetiapine Fumarate; Rats; Tight Junctions; Zonula Occludens-1 Protein

2018
Electrospinning of in situ crosslinked recombinant human collagen peptide/chitosan nanofibers for wound healing.
    Biomaterials science, 2018, Jul-24, Volume: 6, Issue:8

    Topics: Animals; Cell Proliferation; Cell Survival; Chitosan; Collagen; Cross-Linking Reagents; Disease Models, Animal; Electrochemical Techniques; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Nanofibers; NIH 3T3 Cells; Particle Size; Peptides; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Wound Healing

2018
Injectable antibacterial conductive nanocomposite cryogels with rapid shape recovery for noncompressible hemorrhage and wound healing.
    Nature communications, 2018, 07-17, Volume: 9, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bandages; Chitosan; Cryogels; Disease Models, Animal; Epoxy Compounds; Hemorrhage; Hemostasis; Hemostatics; Liver; Male; Methacrylates; Mice; Nanocomposites; Nanotubes, Carbon; Poloxamer; Rabbits; Wound Healing

2018
Improvement of bone microarchitecture in methylprednisolone induced rat model of osteoporosis by using thiolated chitosan-based risedronate mucoadhesive film.
    Drug development and industrial pharmacy, 2018, Volume: 44, Issue:11

    Topics: Animals; Bone and Bones; Chitosan; Disease Models, Animal; Drug Compounding; Female; Methylprednisolone; Microscopy, Electron, Scanning; Osteoporosis; Rats; Risedronic Acid; Spectroscopy, Fourier Transform Infrared; Thermogravimetry

2018
Functional Comparison of High and Low Molecular Weight Chitosan on Lipid Metabolism and Signals in High-Fat Diet-Fed Rats.
    Marine drugs, 2018, Jul-29, Volume: 16, Issue:8

    Topics: Animals; Anticholesteremic Agents; Blood Glucose; Chitosan; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Lipid Metabolism; Lipids; Lipogenesis; Liver; Male; Metabolic Syndrome; Molecular Weight; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

2018
A mucoadhesive thermosensitive hydrogel containing erythropoietin as a potential treatment in oral mucositis: in vitro and in vivo studies.
    Drug delivery and translational research, 2018, Volume: 8, Issue:5

    Topics: Animals; Cattle; Chitosan; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Erythropoietin; Glycerophosphates; Humans; Hydrogels; Rats; Rats, Sprague-Dawley; Stomatitis; Temperature

2018
Poly (ɛ-caprolactone)-chitosan-poly (vinyl alcohol) nanofibrous scaffolds for skin excisional and burn wounds in a canine model.
    IET nanobiotechnology, 2018, Volume: 12, Issue:5

    Topics: Animals; Burns; Chitosan; Dermatologic Surgical Procedures; Disease Models, Animal; Dogs; Histocytochemistry; Male; Nanofibers; Polyesters; Polyvinyl Alcohol; Skin; Tissue Engineering; Tissue Scaffolds; Wound Healing

2018
Biocompatibility and Targeting Efficiency of Encapsulated Quinapyramine Sulfate-Loaded Chitosan-Mannitol Nanoparticles in a Rabbit Model of Surra.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:11

    Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; HeLa Cells; Humans; Mannitol; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Quality of Life; Quinolinium Compounds; Rabbits; Trypanosoma

2018
Pharmacokinetics and pharmacodynamics of intranasally administered selegiline nanoparticles with improved brain delivery in Parkinson's disease.
    Nanomedicine : nanotechnology, biology, and medicine, 2018, Volume: 14, Issue:8

    Topics: Administration, Intranasal; Animals; Antiparkinson Agents; Behavior, Animal; Biological Availability; Brain; Chitosan; Disease Models, Animal; Drug Carriers; Drug Liberation; Male; Nanoparticles; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline; Tissue Distribution

2018
Fluorinated methacrylamide chitosan hydrogel dressings enhance healing in an acute porcine wound model.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: Acrylamides; Acute Disease; Animals; Bandages; Chitosan; Disease Models, Animal; Fluorocarbon Polymers; Hydrogels; Swine; Wound Healing; Wounds and Injuries

2018
Simultaneous formulation of influenza vaccine and chitosan nanoparticles within CpG oligodesoxi nucleotides leads to dose-sparing and protects against lethal challenge in the mouse model.
    Pathogens and disease, 2018, 11-01, Volume: 76, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Viral; Body Weight; Cell Proliferation; Chitosan; Cytokines; Disease Models, Animal; Drug Carriers; Enzyme-Linked Immunospot Assay; Female; Immunoglobulin G; Influenza Vaccines; Injections, Intradermal; Leukocytes, Mononuclear; Mice, Inbred BALB C; Nanoparticles; Oligodeoxyribonucleotides; Orthomyxoviridae Infections; Survival Analysis; Treatment Outcome; Vaccines, Inactivated

2018
GRGDS-functionalized chitosan nanoparticles as a potential intravenous hemostat for traumatic hemorrhage control in an animal model.
    Nanomedicine : nanotechnology, biology, and medicine, 2018, Volume: 14, Issue:8

    Topics: Animals; Chitosan; Disease Models, Animal; Female; Hemorrhage; Hemostatics; Liver; Male; Mice, Inbred BALB C; Nanoparticles; Oligopeptides; Polyethylene Glycols; Rats; Rats, Sprague-Dawley

2018
Chitosan/silk fibroin modified nanofibrous patches with mesenchymal stem cells prevent heart remodeling post-myocardial infarction in rats.
    Acta biomaterialia, 2018, 10-15, Volume: 80

    Topics: Adipose Tissue; Animals; Apoptosis; Biomarkers; Cell Survival; Cellulose; Chitosan; Disease Models, Animal; Fibroins; Heart Function Tests; Hemodynamics; Implants, Experimental; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Transgenic; Myocardial Infarction; Nanofibers; Neovascularization, Physiologic; Organ Size; Rats, Sprague-Dawley; Static Electricity; Ventricular Remodeling; Water

2018
Efficacy of chitosan, a natural polysaccharide, against Cryptosporidium parvum in vitro and in vivo in neonatal mice.
    Experimental parasitology, 2018, Volume: 194

    Topics: Animals; Animals, Newborn; Antiprotozoal Agents; Caco-2 Cells; Cattle; Cell Line, Tumor; Chitosan; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Humans; Intestinal Diseases, Parasitic; Mice; Paromomycin

2018
Soy genistein administered in soluble chitosan microcapsules maintains antioxidant activity and limits intestinal inflammation.
    The Journal of nutritional biochemistry, 2018, Volume: 62

    Topics: Administration, Oral; Animals; Antioxidants; Chitosan; Colitis; Cytokines; Dietary Supplements; Disease Models, Animal; Drug Compounding; Female; Genistein; Glycine max; Interleukin-10; Mice, Inbred C57BL; Oxidative Stress; Solubility

2018
The Cocktail Effect of BMP-2 and TGF-β1 Loaded in Visible Light-Cured Glycol Chitosan Hydrogels for the Enhancement of Bone Formation in a Rat Tibial Defect Model.
    Marine drugs, 2018, Sep-25, Volume: 16, Issue:10

    Topics: Animals; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Liberation; Drug Synergism; Humans; Hydrogels; Light; Male; Osteoblasts; Osteogenesis; Rats; Rats, Wistar; Tibia; Tissue Scaffolds; Transforming Growth Factor beta1; Treatment Outcome; Wounds and Injuries; X-Ray Microtomography

2018
Use of collagen/chitosan sponges mineralized with hydroxyapatite for the repair of cranial defects in rats.
    Injury, 2018, Volume: 49, Issue:12

    Topics: Animals; Biocompatible Materials; Bone Morphogenetic Protein 2; Bone Substitutes; Cell Adhesion; Cell Proliferation; Chitosan; Collagen; Disease Models, Animal; Durapatite; Male; Osteogenesis; Rats; Rats, Wistar; Skull Fractures

2018
Nose to Brain Delivery of Galantamine Loaded Nanoparticles: In-vivo Pharmacodynamic and Biochemical Study in Mice.
    Current drug delivery, 2019, Volume: 16, Issue:1

    Topics: Acetylcholinesterase; Adhesiveness; Administration, Intranasal; Administration, Oral; Alzheimer Disease; Animals; Behavior, Animal; Biological Availability; Blood-Brain Barrier; Chitosan; Cholinesterase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Galantamine; Humans; Male; Maze Learning; Mice; Nanoparticles; Nasal Mucosa; Nootropic Agents; Piracetam; Scopolamine; Treatment Outcome

2019
Preparation of self-regulating/anti-adhesive hydrogels and their ability to promote healing in burn wounds.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2019, Volume: 107, Issue:5

    Topics: Alginates; Animals; Burns; Carboxymethylcellulose Sodium; Chitosan; Disease Models, Animal; Hydrogels; Male; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Wound Healing; Wounds and Injuries

2019
Chitosan-based sleeves loaded with silver and chlorhexidine in a percutaneous rabbit tibia model with a repeated bacterial challenge.
    Acta biomaterialia, 2018, Volume: 82

    Topics: Animals; Anti-Bacterial Agents; Chitosan; Chlorhexidine; Coated Materials, Biocompatible; Disease Models, Animal; Rabbits; Silver; Staphylococcal Infections; Staphylococcus aureus; Surgical Wound Infection; Tibia

2018
A rapid hemostatic sponge based on large, mesoporous silica nanoparticles and N-alkylated chitosan.
    Nanoscale, 2018, Nov-08, Volume: 10, Issue:43

    Topics: Adsorption; Animals; Anticoagulants; Bandages; Biocompatible Materials; Blood Platelets; Cell Adhesion; Cell Survival; Chitosan; Disease Models, Animal; Femoral Artery; Glycerol; Hemolysis; Hemorrhage; Nanoparticles; Porosity; Rabbits; Rats; Silicon Dioxide; Thrombelastography

2018
Nitrosalicyl-imine-chitosan hydrogels based drug delivery systems for long term sustained release in local therapy.
    Journal of colloid and interface science, 2019, Feb-15, Volume: 536

    Topics: Animals; Chitosan; Diclofenac; Disease Models, Animal; Drug Delivery Systems; Hydrogels; Imines; Male; Nitro Compounds; Nociceptive Pain; Particle Size; Rats; Rats, Wistar; Salicylic Acid; Surface Properties

2019
Influence of Preparation Methods of Chitooligosaccharides on Their Physicochemical Properties and Their Anti-Inflammatory Effects in Mice and in RAW264.7 Macrophages.
    Marine drugs, 2018, Nov-02, Volume: 16, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Chitin; Chitosan; Disease Models, Animal; Glycoside Hydrolases; Humans; Hydrolysis; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Molecular Structure; Oligosaccharides; RAW 264.7 Cells; Structure-Activity Relationship; Treatment Outcome

2018
Impediment of selenite-induced cataract in rats by combinatorial drug laden liposomal preparation.
    The Libyan journal of medicine, 2019, Volume: 14, Issue:1

    Topics: Administration, Topical; Animals; Cataract; Chitosan; Disease Models, Animal; Drug Delivery Systems; Lens, Crystalline; Liposomes; Rats; Rats, Sprague-Dawley; Selenious Acid

2019
Chitosan Oligosaccharides Improve Glucolipid Metabolism Disorder in Liver by Suppression of Obesity-Related Inflammation and Restoration of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ).
    Marine drugs, 2018, Nov-19, Volume: 16, Issue:11

    Topics: Animals; Chitosan; Cytokines; Diet, High-Fat; Disease Models, Animal; Glycolipids; Hep G2 Cells; Humans; Inflammation Mediators; Lipid Metabolism; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Oligosaccharides; PPAR gamma; Treatment Outcome; Up-Regulation

2018
Prevention of hepatic stellate cell activation using JQ1- and atorvastatin-loaded chitosan nanoparticles as a promising approach in therapy of liver fibrosis.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 134

    Topics: Actins; Animals; Atorvastatin; Azepines; Carbon Tetrachloride; Chitosan; Disease Models, Animal; Drug Carriers; Drug Evaluation, Preclinical; Drug Synergism; HEK293 Cells; Hepatic Stellate Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Male; Mice; Nanoparticles; Nuclear Proteins; Transcription Factors; Treatment Outcome; Triazoles; Vitamin A

2019
[Evaluation of chitosan-based nasal dressing in animal model].
    Orvosi hetilap, 2018, Volume: 159, Issue:47

    Topics: Administration, Intranasal; Animals; Anti-Bacterial Agents; Bandages; Chitosan; Disease Models, Animal; Nose; Paranasal Sinuses; Postoperative Hemorrhage; Rabbits

2018
Enhancement of wound healing by single-wall/multi-wall carbon nanotubes complexed with chitosan.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Chitosan; Collagen; Connective Tissue; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Inflammation; Male; Mice; Nanotubes, Carbon; Tissue Engineering; Wound Healing

2018
Prostaglandin E
    Theranostics, 2018, Volume: 8, Issue:19

    Topics: Animals; Cells, Cultured; Chitosan; Dinoprostone; Disease Models, Animal; Drug Carriers; Hydrogel, Polyethylene Glycol Dimethacrylate; Immunologic Factors; Inflammation; Luminescent Measurements; Macrophage Activation; Macrophages, Peritoneal; Mice; Molecular Imaging; Neovascularization, Physiologic; Treatment Outcome; Wound Healing; Wounds and Injuries

2018
Chitosan Nanoparticles Loaded with Whole and Soluble Leishmania Antigens, and Evaluation of Their Immunogenecity in a Mouse Model of Leishmaniasis.
    Iranian journal of immunology : IJI, 2018, Volume: 15, Issue:4

    Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Cells, Cultured; Chitosan; Disease Models, Animal; Female; Humans; Interferon-gamma; Interleukin-4; Leishmania; Leishmaniasis; Leishmaniasis Vaccines; Mice; Mice, Inbred BALB C; Nanoparticles; Th1 Cells; Th1-Th2 Balance; Th2 Cells; Vaccination

2018
Lithospermi radix extract-containing bilayer nanofiber scaffold for promoting wound healing in a rat model.
    Materials science & engineering. C, Materials for biological applications, 2019, Volume: 96

    Topics: Animals; Cell Line; Chitosan; Disease Models, Animal; Drug Implants; Lithospermum; Male; Mice; Nanofibers; Plant Extracts; Rats; Rats, Sprague-Dawley; Wound Healing; Wounds and Injuries

2019
Targeted Interleukin-22 Gene Delivery in the Liver by Polymetformin and Penetratin-Based Hybrid Nanoparticles to Treat Nonalcoholic Fatty Liver Disease.
    ACS applied materials & interfaces, 2019, Feb-06, Volume: 11, Issue:5

    Topics: Animals; Cell-Penetrating Peptides; Chitosan; Diet, High-Fat; Disease Models, Animal; Gene Transfer Techniques; Hep G2 Cells; Humans; Interleukin-22; Interleukins; Male; Metformin; Mice; Mice, Inbred C57BL; Nanoparticles; Non-alcoholic Fatty Liver Disease

2019
Prevention of EHEC infection by chitosan nano-structure coupled with synthetic recombinant antigen.
    Journal of microbiological methods, 2019, Volume: 157

    Topics: Adhesins, Bacterial; Animals; Antibodies, Bacterial; Bacterial Adhesion; Caco-2 Cells; Cell Line, Tumor; Chitosan; Disease Models, Animal; Escherichia coli Infections; Escherichia coli O157; Escherichia coli Proteins; Escherichia coli Vaccines; Female; Humans; Immunoglobulin A; Immunoglobulin G; Mice; Mice, Inbred BALB C; Nanoparticles; Receptors, Cell Surface; Recombinant Fusion Proteins; Vaccination

2019
Comparative Efficacy of Chitosan, Pectin Based Mesalamine Colon Targeted Drug Delivery Systems on TNBS-induced IBD Model Rats.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2020, Volume: 19, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Chitosan; Colon; Disease Models, Animal; Drug Delivery Systems; Humans; Inflammatory Bowel Diseases; Mesalamine; Pectins; Rats; Rats, Wistar; Reactive Oxygen Species; Trinitrobenzenesulfonic Acid; Ulcer

2020
Silver nanoparticle impregnated chitosan-PEG hydrogel enhances wound healing in diabetes induced rabbits.
    International journal of pharmaceutics, 2019, Mar-25, Volume: 559

    Topics: Animals; Anti-Bacterial Agents; Bandages; Biocompatible Materials; Chitosan; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Escherichia coli; Hydrogels; Metal Nanoparticles; Rabbits; Silver; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; Wound Healing

2019
Protective Effect of Low Molecular Weight Seleno-Aminopolysaccharide on the Intestinal Mucosal Oxidative Damage.
    Marine drugs, 2019, Jan-18, Volume: 17, Issue:1

    Topics: Animals; Animals, Suckling; Chitosan; Diarrhea, Infantile; Dietary Supplements; Disease Models, Animal; Humans; Infant; Intestinal Mucosa; Kelch-Like ECH-Associated Protein 1; Male; Microscopy, Electron, Scanning; Molecular Weight; NF-E2-Related Factor 2; Oxidative Stress; Selenium; Signal Transduction; Stress, Physiological; Sus scrofa; Treatment Outcome; Weaning

2019
Injectable freeze-dried chitosan-platelet-rich-plasma implants improve marrow-stimulated cartilage repair in a chronic-defect rabbit model.
    Journal of tissue engineering and regenerative medicine, 2019, Volume: 13, Issue:4

    Topics: Animals; Bone Marrow; Bone Remodeling; Cartilage, Articular; Chitosan; Disease Models, Animal; Female; Freeze Drying; Inflammation; Injections; Pilot Projects; Platelet-Rich Plasma; Prostheses and Implants; Prosthesis Implantation; Rabbits; Wound Healing

2019
A comparison between adjuvant and delivering functions of calcium phosphate, aluminum hydroxide and chitosan nanoparticles, using a model protein of Brucella melitensis Omp31.
    Immunology letters, 2019, Volume: 207

    Topics: Adjuvants, Immunologic; Aluminum Hydroxide; Animals; Bacterial Outer Membrane Proteins; Bacterial Vaccines; Brucella melitensis; Brucellosis; Calcium Phosphates; Chitosan; Disease Models, Animal; Disease Resistance; Drug Delivery Systems; Female; Humans; Mice; Mice, Inbred BALB C; Nanoparticles; Th1 Cells; Th2 Cells; Vaccination

2019
Therapeutic Effect of Chitooligosaccharide Tablets on Lipids in High-Fat Diets Induced Hyperlipidemic Rats.
    Molecules (Basel, Switzerland), 2019, Jan-31, Volume: 24, Issue:3

    Topics: Adipose Tissue; Adiposity; Animals; Biomarkers; Chitin; Chitosan; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Hyperlipidemias; Kidney; Lipid Metabolism; Lipids; Liver; Oligosaccharides; Oxidation-Reduction; Rats; Tablets

2019
[Experimental study on crosslinked-chitosan in treatment of knee osteoarthritis in rabbits].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2019, 02-15, Volume: 33, Issue:2

    Topics: Animals; Cartilage, Articular; Chitosan; Chondrocytes; Disease Models, Animal; Knee Joint; Osteoarthritis, Knee; Rabbits; Random Allocation

2019
LINGO-1 siRNA nanoparticles promote central remyelination in ethidium bromide-induced demyelination in rats.
    Journal of physiology and biochemistry, 2019, Volume: 75, Issue:1

    Topics: Administration, Intranasal; Animals; Ataxia; Caspase 3; Chitosan; Demyelinating Diseases; Disease Models, Animal; Drug Carriers; Drug Compounding; Ethidium; Gene Expression Regulation; Male; Membrane Proteins; Myelin Basic Protein; Myelin Sheath; Nanoparticles; Nerve Tissue Proteins; Neuroprotective Agents; Nucleus Raphe Magnus; Rats; Rats, Wistar; Remyelination; RNA, Small Interfering; Stereotaxic Techniques

2019
Alginate/chitosan microcapsules for in-situ delivery of the protein, interleukin-1 receptor antagonist (IL-1Ra), for the treatment of dextran sulfate sodium (DSS)-induced colitis in a mouse model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 137

    Topics: Alginates; Animals; Capsules; Chitosan; Colitis; Dextran Sulfate; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Liberation; Female; Hydrogen-Ion Concentration; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Mice; Mice, Inbred BALB C; Treatment Outcome; Tumor Necrosis Factor-alpha

2019
Expanding Hydrophobically Modified Chitosan Foam for Internal Surgical Hemostasis: Safety Evaluation in a Murine Model.
    The Journal of surgical research, 2019, Volume: 239

    Topics: Animals; Blood Loss, Surgical; Chitosan; Disease Models, Animal; Fibrin Tissue Adhesive; Hemostasis, Surgical; Hemostatics; Humans; Hydrophobic and Hydrophilic Interactions; Liver; Male; Mice; Rats; Rats, Sprague-Dawley

2019
Repair of osteochondral defects using injectable chitosan-based hydrogel encapsulated synovial fluid-derived mesenchymal stem cells in a rabbit model.
    Materials science & engineering. C, Materials for biological applications, 2019, Volume: 99

    Topics: Animals; Cartilage, Articular; Cell Differentiation; Cell Lineage; Cell Proliferation; Chitosan; Disease Models, Animal; Elastic Modulus; Female; Hydrogels; Injections; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rabbits; Rheology; Synovial Fluid; Wound Healing

2019
Chitosan sponges as a sustained release carrier system for the prophylaxis of orthopedic implant-associated infections.
    International journal of biological macromolecules, 2019, Aug-01, Volume: 134

    Topics: Animals; Anti-Infective Agents; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Liberation; Male; Prostheses and Implants; Rats; Surgical Wound Infection; Tissue Distribution

2019
Mesenchymal stem cells-curcumin loaded chitosan nanoparticles hybrid vectors for tumor-tropic therapy.
    International journal of biological macromolecules, 2019, Aug-01, Volume: 134

    Topics: Animals; Biotin; Cell Movement; Cell Survival; Chitosan; Curcumin; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Liberation; Fluorescent Antibody Technique; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Nanoparticles; Neoplasms; Polymers; Tumor Burden; Xenograft Model Antitumor Assays

2019
Synthesis of
    Anticancer research, 2019, Volume: 39, Issue:5

    Topics: Acetates; Animals; Chelating Agents; Chitosan; Disease Models, Animal; Female; Folate Receptor 1; Folic Acid; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Magnetic Resonance Imaging; Mice; Nanoparticles; Ovarian Neoplasms; Polyglutamic Acid; Positron-Emission Tomography

2019
Absorbable hemostatic hydrogels comprising composites of sacrificial templates and honeycomb-like nanofibrous mats of chitosan.
    Nature communications, 2019, 05-24, Volume: 10, Issue:1

    Topics: Animals; Bandages; Biocompatible Materials; Chitosan; Cyclodextrins; Disease Models, Animal; Female; Hemorrhage; Hemostatic Techniques; Hemostatics; Humans; Hydrogels; Male; Nanofibers; Rabbits; Rats; Rats, Sprague-Dawley; Sus scrofa; Treatment Outcome

2019
New basic insights on the potential of a chitosan-based medical device for improving functional recovery after radical prostatectomy.
    BJU international, 2019, Volume: 124, Issue:6

    Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Cells, Cultured; Chitosan; Disease Models, Animal; Female; Ganglia, Autonomic; Humans; Male; Median Nerve; Nerve Regeneration; Prostatectomy; Prostatic Neoplasms; Prostheses and Implants; Rats; Rats, Wistar; Recovery of Function

2019
Characterization of a novel polyvinyl alcohol/chitosan porous hydrogel combined with bone marrow mesenchymal stem cells and its application in articular cartilage repair.
    BMC musculoskeletal disorders, 2019, May-29, Volume: 20, Issue:1

    Topics: Animals; Biocompatible Materials; Cartilage Diseases; Cartilage, Articular; Cell Proliferation; Chitosan; Chondrogenesis; Combined Modality Therapy; Disease Models, Animal; Humans; Hydrogels; Male; Materials Testing; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Polyvinyl Alcohol; Porosity; Rabbits; Regeneration; Tissue Scaffolds; Toxicity Tests; Treatment Outcome; Wound Healing

2019
Synthesis of chitosan derivatives with organoselenium and organosulfur compounds: Characterization, antimicrobial properties and application as biomaterials.
    Carbohydrate polymers, 2019, Sep-01, Volume: 219

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Candida albicans; Chalcogens; Chitosan; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Animal; Escherichia coli; Mice; Mice, Inbred BALB C; Organoselenium Compounds; Peroxidase; Reactive Oxygen Species; Schiff Bases; Staphylococcus aureus

2019
Chitosan oligosaccharide-mediated attenuation of LPS-induced inflammation in IPEC-J2 cells is related to the TLR4/NF-κB signaling pathway.
    Carbohydrate polymers, 2019, Sep-01, Volume: 219

    Topics: Animals; Cell Proliferation; Cells, Cultured; Chitosan; Colitis; Dextran Sulfate; Disease Models, Animal; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Oligosaccharides; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA

2019
Immunization against Vibrio cholerae, ETEC, and EHEC with chitosan nanoparticle containing LSC chimeric protein.
    Microbial pathogenesis, 2019, Volume: 134

    Topics: Animals; Antibodies, Bacterial; Bacterial Toxins; Bacterial Vaccines; Chitosan; Cholera Toxin; Diarrhea; Disease Models, Animal; Enterohemorrhagic Escherichia coli; Enterotoxigenic Escherichia coli; Escherichia coli Infections; Gene Expression Regulation, Bacterial; Immunity, Mucosal; Immunization; Immunoglobulin A; Immunoglobulin G; Mice, Inbred BALB C; Nanoparticles; Particle Size; Recombinant Fusion Proteins; Shiga Toxins; Survival Analysis; Vaccination; Vibrio cholerae

2019
Chitosan Oligosaccharide Exerts Anti-Allergic Effect against Shrimp Tropomyosin-Induced Food Allergy by Affecting Th1 and Th2 Cytokines.
    International archives of allergy and immunology, 2019, Volume: 180, Issue:1

    Topics: Allergens; Animals; Anti-Allergic Agents; Chitosan; Crustacea; Cytokines; Disease Models, Animal; Food Hypersensitivity; Histamine Release; Immunoglobulin E; Immunoglobulin G; Mice; Oligosaccharides; Phenotype; Th1 Cells; Th2 Cells; Tropomyosin

2019
The effectiveness of chitosan-mediated silencing of PDGF-B and PDGFR-β in the mesangial proliferative glomerulonephritis therapy.
    Experimental and molecular pathology, 2019, Volume: 110

    Topics: Animals; Apoptosis; Cell Proliferation; Chitosan; Disease Models, Animal; Glomerulonephritis; Humans; Male; Mesangial Cells; Nanoparticles; Proto-Oncogene Proteins c-sis; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; RNA Interference; RNA, Small Interfering

2019
Chitosan Oligosaccharide Ameliorates Nonalcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Mice.
    Marine drugs, 2019, Jul-02, Volume: 17, Issue:7

    Topics: Administration, Oral; Animals; Chitosan; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Fatty Acids, Nonesterified; Gastrointestinal Microbiome; Humans; Lipid Metabolism; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Oligosaccharides; Protective Agents; Triglycerides

2019
Wound Healing and Antimicrobial Effects of Chitosan-hydrogel/Honey Compounds in a Rat Full-thickness Wound Model.
    Wounds : a compendium of clinical research and practice, 2019, Volume: 31, Issue:9

    Topics: Animals; Anti-Infective Agents; Bandages; Candida albicans; Chitosan; Disease Models, Animal; Escherichia coli; Honey; Hydrogels; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Rats; Staphylococcus aureus; Wound Healing; Wounds and Injuries

2019
Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering.
    Nature communications, 2019, 08-06, Volume: 10, Issue:1

    Topics: Animals; Bentonite; Biocompatible Materials; Bone Regeneration; Cell Differentiation; Chitosan; Disease Models, Animal; Elastic Modulus; Humans; Hydrogels; Male; Mesenchymal Stem Cells; Mice; Nanocomposites; Osteogenesis; Skull; Tissue Engineering; Wound Healing; X-Ray Microtomography

2019
Chitosan/poly(vinyl alcohol) hydrogel combined with Ad-hTGF-β1 transfected mesenchymal stem cells to repair rabbit articular cartilage defects.
    Experimental biology and medicine (Maywood, N.J.), 2013, Volume: 238, Issue:1

    Topics: Animals; Cartilage, Articular; Chitosan; Disease Models, Animal; Drug Carriers; Histocytochemistry; Hydrogel, Polyethylene Glycol Dimethacrylate; Immunohistochemistry; Knee Injuries; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Polyvinyl Alcohol; Rabbits; Recombinant Proteins; Transforming Growth Factor beta1; Treatment Outcome

2013
Hyperacute direct thrombus imaging using computed tomography and gold nanoparticles.
    Annals of neurology, 2013, Volume: 73, Issue:5

    Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Brain Mapping; Chitosan; Disease Models, Animal; Gold; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Nanoparticles; Thrombosis; Time Factors; Tissue Plasminogen Activator; Tomography, X-Ray Computed

2013
Chitosan nanoparticle carrying small interfering RNA to platelet-derived growth factor B mRNA inhibits proliferation of smooth muscle cells in rabbit injured arteries.
    Vascular, 2013, Volume: 21, Issue:5

    Topics: Angioplasty, Balloon; Animals; Cell Proliferation; Chitosan; Disease Models, Animal; Iliac Artery; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nanoparticles; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-sis; Rabbits; RNA Interference; RNA, Small Interfering; RNAi Therapeutics; Transfection; Ultrasonics; Vascular System Injuries

2013
Stereological analysis of subchondral angiogenesis induced by chitosan and coagulation factors in microdrilled articular cartilage defects.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:6

    Topics: Animals; Biocompatible Materials; Cartilage, Articular; Case-Control Studies; Chitosan; Collagen Type I; Collagen Type II; Disease Models, Animal; Factor VIIa; Female; Glycosaminoglycans; Hemostatics; Hindlimb; Male; Rabbits; Recombinant Proteins; Thrombin; Wound Healing

2013
Effect of alginate-chitosan sustained release microcapsules for transhepatic arterial embolization in VX2 rabbit liver cancer model.
    Journal of biomedical materials research. Part A, 2013, Volume: 101, Issue:11

    Topics: Alginates; Animals; Aspartate Aminotransferases; Cell Proliferation; Chitosan; Disease Models, Animal; Embolization, Therapeutic; Glucuronic Acid; Hepatic Artery; Hexuronic Acids; Hydrogen-Ion Concentration; Liver Neoplasms; Microscopy, Electron, Scanning; Microspheres; Prosthesis Implantation; Rabbits; Radiography

2013
Development of a novel emergency hemostatic kit for severe hemorrhage.
    Artificial organs, 2013, Volume: 37, Issue:5

    Topics: Alginates; Animals; Biomarkers; Chitosan; Disease Models, Animal; Electric Power Supplies; Emergency Medical Services; Glucuronic Acid; Hemorrhage; Hemostatic Techniques; Hemostatics; Hexuronic Acids; Hydrogels; Male; Photochemical Processes; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors; Ultraviolet Rays

2013
Rapid sciatic nerve regeneration of rats by a surface modified collagen-chitosan scaffold.
    Injury, 2013, Volume: 44, Issue:7

    Topics: Animals; Biocompatible Materials; Chitosan; Collagen; Disease Models, Animal; Male; Nerve Regeneration; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tissue Engineering; Tissue Scaffolds; Wound Healing

2013
[In vivo experiment of porous bioactive bone cement modified by bioglass and chitosan].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2013, Volume: 27, Issue:3

    Topics: Animals; Biocompatible Materials; Bone Cements; Ceramics; Chitosan; Compressive Strength; Disease Models, Animal; Elasticity; Female; Femur; Male; Materials Testing; Osteogenesis; Polymethyl Methacrylate; Porosity; Powders; Rabbits; Random Allocation; Stress, Mechanical; Tissue Engineering

2013
The efficacy and safety of chitosan dextran gel in a burr hole neurosurgical sheep model.
    Acta neurochirurgica, 2013, Volume: 155, Issue:7

    Topics: Animals; Biocompatible Materials; Chitosan; Dextrans; Disease Models, Animal; Gels; Hemorrhage; Magnetic Resonance Imaging; Neurosurgical Procedures; Sheep; Tissue Adhesions

2013
Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt A

    Topics: Analgesics; Animals; Blood-Brain Barrier; Brain; Cations; Chitosan; Cholinesterases; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Endorphins; Enkephalin, Leucine; Furans; Male; Mice; Mice, Inbred ICR; Nanoparticles; Pain; Peptides; Pyridones; Tissue Distribution

2013
Chitosan-dextran sulphate nanocapsule drug delivery system as an effective therapeutic against intraphagosomal pathogen Salmonella.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Cell Line; Chitosan; Ciprofloxacin; Dextran Sulfate; Disease Models, Animal; Drug Delivery Systems; Epithelial Cells; Macrophages; Mice; Mice, Inbred BALB C; Nanocapsules; Phagosomes; Salmonella; Salmonella Infections, Animal; Treatment Outcome

2013
Oral administration of chitin and chitosan prevents peanut-induced anaphylaxis in a murine food allergy model.
    International journal of biological macromolecules, 2013, Volume: 61

    Topics: Administration, Oral; Anaphylaxis; Animals; Arachis; Chitin; Chitosan; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Mice; Peanut Hypersensitivity; Spleen; Th1 Cells; Th2 Cells

2013
[The production of mouse model of slowly progressive diabetes mellitus and the preventive effect of low molecular weight chitosan on the progression of the diabetes mellitus].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2013, Volume: 133, Issue:7

    Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Male; Mice; Molecular Weight; Streptozocin

2013
Glucose-responsive microgels integrated with enzyme nanocapsules for closed-loop insulin delivery.
    ACS nano, 2013, Aug-27, Volume: 7, Issue:8

    Topics: Animals; Blood Glucose; Catalysis; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Enzymes; Gels; Gluconates; Glucose; Humans; Hydrogen-Ion Concentration; Hyperglycemia; Insulin; Mice; Microscopy, Electron, Transmission; Nanocapsules; Recombinant Proteins; Time Factors

2013
Increased neuronal survival in the brainstem during liver injury: role of γ-aminobutyric acid and serotonin chitosan nanoparticles.
    Journal of neuroscience research, 2013, Volume: 91, Issue:9

    Topics: Animals; bcl-2-Associated X Protein; Biocompatible Materials; Brain Stem; Caspase 8; Cell Survival; Chemical and Drug Induced Liver Injury; Chitosan; Disease Models, Animal; gamma-Aminobutyric Acid; Male; Nanoparticles; Neurons; NF-kappa B; Psychomotor Performance; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, GABA-B; Serotonin; Tumor Necrosis Factor-alpha; Type C Phospholipases

2013
[Experimental study on hemostasis of thermosensitive chitosan hemostatic film].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2013, Volume: 27, Issue:5

    Topics: Animals; Cellulose; Chitosan; Disease Models, Animal; Female; Hemorrhage; Hemostasis; Hemostatics; Liver; Male; Materials Testing; Membranes, Artificial; Random Allocation; Rats; Rats, Sprague-Dawley; Temperature

2013
A novel chitosan based antimalarial drug delivery against Plasmodium berghei infection.
    Acta tropica, 2013, Volume: 128, Issue:3

    Topics: Animals; Antimalarials; Chitosan; Chloroquine; Disease Models, Animal; DNA Damage; Drug Carriers; Drug Delivery Systems; Malaria; Mice; Oxidative Stress; Parasitemia; Plasmodium berghei; Treatment Outcome

2013
Development of protective anti-Mycoplasma pneumoniae antibodies after immunization of guinea pigs with the combination of a P1-P30 chimeric recombinant protein and chitosan.
    Microbial pathogenesis, 2013, Volume: 64

    Topics: Adhesins, Bacterial; Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Bacterial; Bacterial Adhesion; Bacterial Load; Bacterial Vaccines; Chitosan; Disease Models, Animal; Epithelial Cells; Guinea Pigs; HeLa Cells; Humans; Injections, Subcutaneous; Lung; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Recombinant Proteins; Vaccination; Vaccines, Synthetic

2013
Subretinal transfection of chitosan-loaded TLR3-siRNA for the treatment of experimental autoimmune uveitis.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt A

    Topics: Animals; Autoimmune Diseases; CD4 Antigens; Chitosan; Cytokines; Disease Models, Animal; Female; Gene Knockdown Techniques; Interferon-gamma; Interleukin-6; Luciferases, Firefly; Mice; Mice, Inbred C57BL; Mice, Transgenic; Retinal Pigment Epithelium; RNA, Small Interfering; Severity of Illness Index; Signal Transduction; Toll-Like Receptor 3; Transfection; Uveitis

2013
TNF-α gene silencing using polymerized siRNA/thiolated glycol chitosan nanoparticles for rheumatoid arthritis.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2014, Volume: 22, Issue:2

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Line; Chitosan; Disease Models, Animal; Gene Expression; Gene Silencing; Macrophages; Male; Mice; Nanoparticles; RNA, Small Interfering; Sulfhydryl Compounds; Treatment Outcome; Tumor Necrosis Factor-alpha

2014
PVA-chitosan composite hydrogel versus alginate beads as a potential mesenchymal stem cell carrier for the treatment of focal cartilage defects.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2015, Volume: 23, Issue:5

    Topics: Alginates; Animals; Biocompatible Materials; Cartilage, Articular; Chitosan; Disease Models, Animal; Drug Carriers; Glucuronic Acid; Hexuronic Acids; Hydrogels; Knee Injuries; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Polyvinyl Alcohol; Rabbits

2015
Differentiation of human adipose-derived stem cells into neuron-like cells which are compatible with photocurable three-dimensional scaffolds.
    Tissue engineering. Part A, 2014, Volume: 20, Issue:7-8

    Topics: Adipose Tissue; Animals; Antigens, CD; Biocompatible Materials; Brain Injuries; Cell Differentiation; Cell Lineage; Cell Shape; Cell Survival; Cells, Cultured; Chitosan; Disease Models, Animal; Gelatin; Humans; Kruppel-Like Factor 4; Magnetic Resonance Spectroscopy; Mice; Multipotent Stem Cells; Neurons; Photochemical Processes; Spectroscopy, Fourier Transform Infrared; Stem Cells; Tissue Scaffolds; Transcription Factors; Ultraviolet Rays

2014
Chitosan dermal substitute and chitosan skin substitute contribute to accelerated full-thickness wound healing in irradiated rats.
    BioMed research international, 2013, Volume: 2013

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Fibroblasts; Humans; Rats; Skin Transplantation; Skin, Artificial; Wound Healing

2013
Endoscopic application of EGF-chitosan hydrogel for precipitated healing of GI peptic ulcers and mucosectomy-induced ulcers.
    Journal of materials science. Materials in medicine, 2014, Volume: 25, Issue:2

    Topics: Animals; Chitosan; Disease Models, Animal; Endoscopy, Gastrointestinal; Epidermal Growth Factor; Female; Gastric Mucosa; Hydrogels; Peptic Ulcer; Rabbits; Swine; Wound Healing

2014
Effect of locally applied transforming growth factor Beta3 on wound healing and stenosis development in tracheal surgery.
    Respiratory care, 2014, Volume: 59, Issue:8

    Topics: Administration, Topical; Animals; Chitosan; Disease Models, Animal; Hemostatics; Male; Rats; Rats, Wistar; Trachea; Tracheal Stenosis; Transforming Growth Factor beta3; Wound Healing

2014
Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles.
    Biomaterials, 2014, Volume: 35, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Glucose; Granulocyte Colony-Stimulating Factor; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Nanoparticles; Neutropenia; Particle Size; Pentetic Acid; Polyglutamic Acid; Positron-Emission Tomography; Proteolysis; Rats; Rats, Wistar; Static Electricity; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2014
Nanoparticles with surface antibody against CD98 and carrying CD98 small interfering RNA reduce colitis in mice.
    Gastroenterology, 2014, Volume: 146, Issue:5

    Topics: Administration, Oral; Alginates; Animals; Cell Line; Chitosan; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Fusion Regulatory Protein-1; Genetic Therapy; Glucuronic Acid; Hexuronic Acids; Homeodomain Proteins; Hydrogels; Interleukin-12; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanomedicine; Nanoparticles; RNA Interference; RNA, Small Interfering; Severity of Illness Index; Single-Chain Antibodies; Time Factors; Tumor Necrosis Factor-alpha

2014
Adipose-derived stem cells and BMP-2 delivery in chitosan-based 3D constructs to enhance bone regeneration in a rat mandibular defect model.
    Tissue engineering. Part A, 2014, Volume: 20, Issue:15-16

    Topics: Adipose Tissue; Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Carrier Proteins; Cell Proliferation; Chitosan; Collagen; Disease Models, Animal; Mandible; Mice, Inbred C57BL; Osteocalcin; Osteogenesis; Rats, Nude; Stem Cell Transplantation; Stem Cells; Tissue Scaffolds; X-Ray Microtomography

2014
Synthesis and evaluation of hydroxycamptothecin-encapsulated chitosan nanospheres for the treatment of liver cancer.
    Technology in cancer research & treatment, 2015, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chitosan; Disease Models, Animal; Drug Compounding; Drug Liberation; Hep G2 Cells; Humans; Liver Neoplasms; Nanospheres; Xenograft Model Antitumor Assays

2015
Role of HGF-loaded nanoparticles in treating rat acute hepatic failure.
    Hepato-gastroenterology, 2013, Volume: 60, Issue:127

    Topics: Animals; Biomarkers; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Female; Hepatocyte Growth Factor; Hepatocytes; Injections, Intraperitoneal; Injections, Intravenous; Ki-67 Antigen; Lactic Acid; Liver Failure, Acute; Liver Regeneration; Male; Mitotic Index; Nanoparticles; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Time Factors

2013
[Effect of succinic acid derivatives and chitosan on the oxidation status of tissues in rats with cerebral ischemia/reperfusion model].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:1

    Topics: Animals; Brain Chemistry; Brain Ischemia; Chitosan; Disease Models, Animal; Free Radicals; Male; Oxidation-Reduction; Rats; Reperfusion Injury; Succinates

2014
Optimised nanoformulation of bromocriptine for direct nose-to-brain delivery: biodistribution, pharmacokinetic and dopamine estimation by ultra-HPLC/mass spectrometry method.
    Expert opinion on drug delivery, 2014, Volume: 11, Issue:6

    Topics: Administration, Intranasal; Animals; Antiparkinson Agents; Biological Availability; Biological Transport; Blood-Brain Barrier; Brain; Bromocriptine; Chitosan; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Drug Delivery Systems; Female; Male; Mass Spectrometry; Mice; Nanoparticles; Nasal Mucosa; Parkinson Disease; Radiopharmaceuticals; Sodium Pertechnetate Tc 99m; Tissue Distribution

2014
Characterization of an injectable chitosan-demineralized bone matrix hybrid for healing critical-size long-bone defects in a rabbit model.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:5

    Topics: Animals; Biocompatible Materials; Bone Demineralization Technique; Bone Matrix; Chitosan; Disease Models, Animal; Freeze Drying; Male; Rabbits; Radiography; Radius; Transplantation, Homologous; Wound Healing

2014
Oral gene therapy for hemophilia B using chitosan-formulated FIX mutants.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:6

    Topics: Administration, Oral; Animals; Chitosan; Disease Models, Animal; Factor IX; Feasibility Studies; Genetic Therapy; Genotype; HEK293 Cells; Hemophilia B; Hemostasis; Humans; Intestine, Small; Liver; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Nanoparticles; Phenotype; Time Factors; Transfection

2014
Therapeutic efficacies of chitosan against Pneumocystis pneumonia of immunosuppressed rat.
    Parasite immunology, 2014, Volume: 36, Issue:7

    Topics: Animals; Anti-Infective Agents; Chitosan; Disease Models, Animal; Female; Flow Cytometry; Immunocompromised Host; Interferons; Interleukin-10; Lung; Lymphocyte Count; Macrophages, Alveolar; Pneumocystis carinii; Pneumonia, Pneumocystis; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; T-Lymphocytes; Tumor Necrosis Factor-alpha

2014
Wound healing efficacy of a chitosan-based film-forming gel containing tyrothricin in various rat wound models.
    Archives of pharmacal research, 2015, Volume: 38, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Chitosan; Disease Models, Animal; Drug Carriers; Female; Gels; Molecular Structure; Rats, Sprague-Dawley; Tyrothricin; Wound Healing; Wounds and Injuries

2015
Foreign body reaction associated with PET and PET/chitosan electrospun nanofibrous abdominal meshes.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Electrochemical Techniques; Foreign-Body Reaction; Granuloma, Foreign-Body; Hernia, Abdominal; Herniorrhaphy; Male; Materials Testing; Nanofibers; Polyethylene Glycols; Polyethylene Terephthalates; Polypropylenes; Rats; Rats, Wistar; Surface Properties; Surgical Mesh; Sutures; Tensile Strength

2014
Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:5

    Topics: Animals; Cell Line; Chitosan; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Nanoparticles; Nose Diseases; Peptides; Pneumonia, Viral; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Viral Fusion Proteins

2014
Synergistic effects of glycated chitosan with high-intensity focused ultrasound on suppression of metastases in a syngeneic breast tumor model.
    Cell death & disease, 2014, Apr-17, Volume: 5

    Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Movement; Chitosan; Diagnostic Imaging; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Genes, Reporter; High-Intensity Focused Ultrasound Ablation; Humans; Macrophages; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Transfection

2014
CSM enhances the filtration bleb survival in rabbit model of experimental glaucoma surgery.
    Current eye research, 2014, Volume: 39, Issue:10

    Topics: Alkylating Agents; Animals; Chitosan; Conjunctiva; Disease Models, Animal; Drug Carriers; Fibrosis; Glaucoma; Injections, Intraocular; Intraocular Pressure; Mitomycin; Postoperative Complications; Rabbits; Trabeculectomy; Wound Healing

2014
Improved antitumor activity and reduced cardiotoxicity of epirubicin using hepatocyte-targeted nanoparticles combined with tocotrienols against hepatocellular carcinoma in mice.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 88, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cardiotoxicity; Cell Survival; Chitosan; Disease Models, Animal; Drug Delivery Systems; Epirubicin; Glutathione; Heart; Hep G2 Cells; Hepatocytes; Humans; Lactic Acid; Lipid Peroxidation; Liver; Liver Neoplasms; Mice; Nanoparticles; Neovascularization, Pathologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Superoxide Dismutase; Tocotrienols; Tumor Suppressor Protein p53

2014
Delivery of alginate-chitosan hydrogel promotes endogenous repair and preserves cardiac function in rats with myocardial infarction.
    Journal of biomedical materials research. Part A, 2015, Volume: 103, Issue:3

    Topics: Alginates; Animals; Apoptosis; Biocompatible Materials; Cell Proliferation; Chitosan; Disease Models, Animal; Fibrosis; Glucuronic Acid; Hexuronic Acids; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Inflammation; Male; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Regeneration; Regenerative Medicine; Shear Strength; Spectroscopy, Fourier Transform Infrared; Temperature; Tissue Engineering; Ventricular Remodeling

2015
Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis.
    Journal of biomaterials applications, 2014, Volume: 29, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Calcium Sulfate; Chitosan; Chronic Disease; Coated Materials, Biocompatible; Daptomycin; Disease Models, Animal; Drug Delivery Systems; Male; Materials Testing; Osteomyelitis; Polymethyl Methacrylate; Prosthesis-Related Infections; Rabbits; Staphylococcal Infections

2014
Floating-bioadhesive gastroretentive Caesalpinia pulcherrima-based beads of amoxicillin trihydrate for Helicobacter pylori eradication.
    Drug delivery, 2016, Volume: 23, Issue:2

    Topics: Adhesiveness; Administration, Oral; Alginates; Amoxicillin; Animals; Anti-Bacterial Agents; Biological Availability; Caesalpinia; Calorimetry, Differential Scanning; Chitosan; Crystallography, X-Ray; Delayed-Action Preparations; Disease Models, Animal; Dosage Forms; Drug Carriers; Drug Compounding; Female; Galactose; Gastric Mucosa; Glucuronic Acid; Helicobacter Infections; Helicobacter pylori; Hexuronic Acids; Kinetics; Male; Mannans; Models, Chemical; Particle Size; Powder Diffraction; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical

2016
In vitro and in vivo evaluation of chitosan graft glyceryl monooleate as peroral delivery carrier of enoxaparin.
    International journal of pharmaceutics, 2014, Aug-25, Volume: 471, Issue:1-2

    Topics: Adhesiveness; Administration, Oral; Animals; Anticoagulants; Caco-2 Cells; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Enoxaparin; Glycerides; Humans; Male; Mice, Inbred Strains; Molecular Structure; Particle Size; Pulmonary Embolism; Rats, Sprague-Dawley; Surface Properties

2014
Oral immunization with recombinant enterovirus 71 VP1 formulated with chitosan protects mice against lethal challenge.
    Virology journal, 2014, May-06, Volume: 11

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antibodies, Neutralizing; Antibodies, Viral; Chitosan; Cytokines; Disease Models, Animal; Enterovirus A, Human; Enterovirus Infections; Female; Immunity, Mucosal; Immunoglobulin A; Immunoglobulin G; Leukocytes, Mononuclear; Mice, Inbred ICR; Recombinant Proteins; Spleen; Survival Analysis; Vaccination; Vaccines, Synthetic; Viral Structural Proteins; Viral Vaccines

2014
FK506-loaded chitosan conduit promotes the regeneration of injured sciatic nerves in the rat through the upregulation of brain-derived neurotrophic factor and TrkB.
    Journal of the neurological sciences, 2014, Sep-15, Volume: 344, Issue:1-2

    Topics: Animals; Biocompatible Materials; Brain-Derived Neurotrophic Factor; Chitosan; Disease Models, Animal; Drug Combinations; Electric Stimulation; Evoked Potentials; GAP-43 Protein; Immunosuppressive Agents; Male; Nerve Regeneration; Neural Conduction; Rats; Rats, Wistar; Receptor, trkB; Sciatic Neuropathy; Tacrolimus; Time Factors; Up-Regulation

2014
M cell-targeting strategy facilitates mucosal immune response and enhances protection against CVB3-induced viral myocarditis elicited by chitosan-DNA vaccine.
    Vaccine, 2014, Jul-31, Volume: 32, Issue:35

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antibodies, Viral; Chitosan; Coxsackievirus Infections; Disease Models, Animal; Enterovirus B, Human; Immunity, Mucosal; Immunoglobulin A, Secretory; Immunoglobulin G; Male; Mice, Inbred BALB C; Myocarditis; T-Lymphocytes; Vaccines, DNA; Viral Load; Viral Vaccines

2014
Preparation and characteristics of thermoresponsive gel of minocycline hydrochloride and evaluation of its effect on experimental periodontitis models.
    Drug delivery, 2016, Volume: 23, Issue:2

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Stability; Female; Gels; Glycerophosphates; Hydrogen-Ion Concentration; Kinetics; Male; Minocycline; Periodontal Pocket; Periodontitis; Porphyromonas gingivalis; Rats, Sprague-Dawley; Solubility; Technology, Pharmaceutical; Temperature; Viscosity

2016
The prevention effect of poly (L-glutamic acid)/chitosan on spinal epidural fibrosis and peridural adhesion in the post-laminectomy rabbit model.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2014, Volume: 23, Issue:11

    Topics: Animals; Biocompatible Materials; Cell Count; Chitosan; Disease Models, Animal; Epidural Space; Fibroblasts; Fibrosis; Foreign-Body Reaction; Laminectomy; Magnetic Resonance Imaging; Polyglutamic Acid; Prostheses and Implants; Rabbits; Tissue Adhesions

2014
Hydrophobically-modified chitosan foam: description and hemostatic efficacy.
    The Journal of surgical research, 2015, Volume: 193, Issue:1

    Topics: Animals; Bandages; Cattle; Chitosan; Disease Models, Animal; Hemorrhage; Hemostatics; Humans; Hydrophobic and Hydrophilic Interactions; Liver; Male; Materials Testing; MCF-7 Cells; Pilot Projects; Rats, Sprague-Dawley; Resuscitation; Wounds and Injuries

2015
Enhanced healing of rat calvarial defects with MSCs loaded on BMP-2 releasing chitosan/alginate/hydroxyapatite scaffolds.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Alginates; Animals; Biocompatible Materials; Biomarkers; Bone Morphogenetic Protein 2; Bone Regeneration; Cell Differentiation; Chitosan; Disease Models, Animal; Durapatite; Glucuronic Acid; Hexuronic Acids; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Rats, Sprague-Dawley; Skull; Tissue Scaffolds; Wound Healing

2014
Chitosan oligosaccharides attenuate ocular inflammation in rats with experimental autoimmune anterior uveitis.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Animals; Aqueous Humor; Chitosan; Disease Models, Animal; Eye; Inflammation; Intercellular Adhesion Molecule-1; NF-kappa B; Oligosaccharides; Rats; Uveitis, Anterior

2014
Macrophage-mediated nanoparticle delivery to the periodontal lesions in established murine model via Pg-LPS induction.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2015, Volume: 44, Issue:7

    Topics: Adoptive Transfer; Alveolar Bone Loss; Animals; Carbocyanines; Chitosan; Disease Models, Animal; Female; Lipopolysaccharides; Macrophages; Mice; Nanoparticles; Periodontitis; Porphyromonas gingivalis; RNA, Small Interfering; RNAi Therapeutics; Tissue Distribution

2015
Systemic Delivery of Free Chitosan Accelerates Femur Fracture Healing in Rats.
    Current drug targets, 2018, Volume: 19, Issue:5

    Topics: Animals; Body Weight; Chitosan; Disease Models, Animal; Femoral Fractures; Fracture Healing; Injections, Intraperitoneal; Male; Random Allocation; Rats; Rats, Sprague-Dawley; X-Ray Microtomography

2018
Immunogenicity of a DNA and Recombinant Protein Vaccine Combining LipL32 and Loa22 for Leptospirosis Using Chitosan as a Delivery System.
    Journal of microbiology and biotechnology, 2015, Volume: 25, Issue:4

    Topics: Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Line; Chitosan; Cytokines; Disease Models, Animal; Female; Humans; Immunity, Cellular; Immunity, Humoral; Immunization; Immunoglobulin G; Leptospira; Leptospirosis; Lipoproteins; Mice; Nanoparticles; Recombinant Proteins; T-Lymphocytes; Vaccination; Vaccines, DNA; Vaccines, Synthetic

2015
Downregulation of immunological mediators in 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions by hydrocortisone-loaded chitosan nanoparticles.
    International journal of nanomedicine, 2014, Volume: 9

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chitosan; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Models, Animal; Down-Regulation; Drug Carriers; Hydrocortisone; Mice; Nanoparticles; Random Allocation

2014
Oral insulin delivery by self-assembled chitosan nanoparticles: in vitro and in vivo studies in diabetic animal model.
    Materials science & engineering. C, Materials for biological applications, 2013, Jan-01, Volume: 33, Issue:1

    Topics: Administration, Oral; Alloxan; Animals; Blood Glucose; Chitosan; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Carriers; Hydrogen-Ion Concentration; Insulin; Mice; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Spectroscopy, Fourier Transform Infrared

2013
Anti-inflammatory effects of orally administered glucosamine oligomer in an experimental model of inflammatory bowel disease.
    Carbohydrate polymers, 2015, Jan-22, Volume: 115

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Body Weight; Chitin; Chitosan; Colon; Cytokines; Disease Models, Animal; Female; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Mice, Inbred C57BL; NF-kappa B; Oligosaccharides; Organ Size; Survival Analysis

2015
Pulsed electromagnetic fields accelerate functional recovery of transected sciatic nerve bridged by chitosan conduit: an animal model study.
    International journal of surgery (London, England), 2014, Volume: 12, Issue:12

    Topics: Administration, Topical; Animals; Biocompatible Materials; Biomechanical Phenomena; Chitosan; Disease Models, Animal; Electromagnetic Fields; Magnetic Field Therapy; Male; Models, Animal; Muscle, Skeletal; Nerve Fibers; Nerve Regeneration; Prostheses and Implants; Random Allocation; Rats; Rats, Wistar; Recovery of Function; Sciatic Nerve

2014
Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model.
    Acta biomaterialia, 2015, Volume: 13

    Topics: Animals; Cell Differentiation; Chitosan; Disease Models, Animal; Gene Transfer Techniques; Hepatocytes; Heterografts; Humans; Induced Pluripotent Stem Cells; Liver Failure; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Polyurethanes

2015
Anti-cancer, pharmacokinetics and tumor localization studies of pH-, RF- and thermo-responsive nanoparticles.
    International journal of biological macromolecules, 2015, Volume: 74

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caprolactam; Cell Line, Tumor; Chitosan; Curcumin; Disease Models, Animal; Drug Delivery Systems; Gold; Humans; Hydrogen-Ion Concentration; Mice; Nanoparticles; Neoplasms; Particle Size; Pulsed Radiofrequency Treatment; Thermodynamics; Tissue Distribution; Tumor Burden

2015
Chitosan/siRNA nanoparticles targeting cyclooxygenase type 2 attenuate unilateral ureteral obstruction-induced kidney injury in mice.
    Theranostics, 2015, Volume: 5, Issue:2

    Topics: Acute Kidney Injury; Animals; Cell Line; Chitosan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Histocytochemistry; Immunohistochemistry; Macrophages; Male; Mice; Microscopy, Confocal; Nanoparticles; Optical Imaging; RNA, Small Interfering; Treatment Outcome; Ureteral Obstruction

2015
Chitosan cocrystals embedded alginate beads for enhancing the solubility and bioavailability of aceclofenac.
    International journal of biological macromolecules, 2015, Volume: 74

    Topics: Alginates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chitosan; Crystallization; Diclofenac; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Glucuronic Acid; Hexuronic Acids; Inflammation; Male; Particle Size; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2015
A new rapamycin-abluminally coated chitosan/heparin stent system accelerates early re-endothelialisation and improves anti-coagulant properties in porcine coronary artery models.
    Clinical and investigative medicine. Medecine clinique et experimentale, 2014, Dec-01, Volume: 37, Issue:6

    Topics: Animals; Anticoagulants; Biocompatible Materials; Chitosan; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Heparin; Immunosuppressive Agents; Sirolimus; Swine

2014
Chitosan inhibits fibroblasts growth in Achilles tendon via TGF-β1/Smad3 pathway by miR-29b.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:12

    Topics: Achilles Tendon; Animals; Biocompatible Materials; Blotting, Western; Cell Proliferation; Chitosan; Disease Models, Animal; Fibroblasts; Flow Cytometry; Male; MicroRNAs; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Tendon Injuries; Tissue Adhesions; Transforming Growth Factor beta1; Wound Healing

2014
Inhalable chitosan nanoparticles as antitubercular drug carriers for an effective treatment of tuberculosis.
    Artificial cells, nanomedicine, and biotechnology, 2016, Volume: 44, Issue:3

    Topics: Administration, Inhalation; Animals; Antibiotics, Antitubercular; Chitosan; Disease Models, Animal; Drug Carriers; Female; Humans; Isoniazid; Mice; Mice, Inbred BALB C; Nanoparticles; Rifampin; Tuberculosis, Pulmonary

2016
Chitosan oligosaccharides in combination with Agaricus blazei Murill extract reduces hepatoma formation in mice with severe combined immunodeficiency.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Agaricus; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinoma, Hepatocellular; Chitosan; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Mice, SCID; Oligosaccharides; Plant Extracts; Severe Combined Immunodeficiency; Vascular Endothelial Growth Factor A

2015
Effect of novel curcumin-encapsulated chitosan-bioglass drug on bone and skin repair after gamma radiation: experimental study on a Wistar rat model.
    Cell biochemistry and function, 2015, Volume: 33, Issue:3

    Topics: Animals; Bone and Bones; Ceramics; Chitosan; Curcumin; Disease Models, Animal; Drug Carriers; Female; Free Radical Scavengers; Gamma Rays; Hydroxyproline; Inflammation Mediators; Rats; Rats, Wistar; Skin; Staphylococcus aureus; Whole-Body Irradiation; Wound Healing

2015
Chitosan Oligosaccharides Attenuate Atherosclerosis and Decrease Non-HDL in ApoE-/- Mice.
    Journal of atherosclerosis and thrombosis, 2015, Volume: 22, Issue:9

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Chitosan; Cholesterol; Cholesterol, HDL; Disease Models, Animal; Hep G2 Cells; Humans; Lipids; Lipoproteins; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Oligosaccharides; Receptors, LDL; Scavenger Receptors, Class B; Triglycerides

2015
Oral delivery of nanoparticles containing anticancer SN38 and hSET1 antisense for dual therapy of colon cancer.
    International journal of biological macromolecules, 2015, Volume: 78

    Topics: Administration, Oral; Animals; Camptothecin; Cell Line, Tumor; Chitosan; Colonic Neoplasms; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug Stability; Histone-Lysine N-Methyltransferase; Humans; Irinotecan; Mice; Nanoparticles; Oligonucleotides, Antisense; Spectroscopy, Fourier Transform Infrared; Xenograft Model Antitumor Assays

2015
Inhibition of interleukin-1beta-stimulated dedifferentiation of chondrocytes via controlled release of CrmA from hyaluronic acid-chitosan microspheres.
    BMC musculoskeletal disorders, 2015, Mar-18, Volume: 16

    Topics: Aggrecans; Animals; Cell Differentiation; Cell Survival; Cells, Cultured; Chitosan; Chondrocytes; Collagen Type I; Collagen Type II; Disease Models, Animal; Glycosaminoglycans; Hyaluronic Acid; In Vitro Techniques; Interleukin-1beta; Microspheres; Osteoarthritis, Knee; Rats; Serpins; Viral Proteins

2015
Enhancement of acute tendon repair using chitosan matrix.
    American journal of orthopedics (Belle Mead, N.J.), 2015, Volume: 44, Issue:5

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Gels; Rats; Rats, Wistar; Rotator Cuff; Rotator Cuff Injuries; Tendon Injuries; Tendons; Wound Healing

2015
AIM2 co-immunization favors specific multifunctional CD8(+) T cell induction and ameliorates coxsackievirus B3-induced chronic myocarditis.
    Antiviral research, 2015, Volume: 119

    Topics: Administration, Intranasal; Animals; CD8-Positive T-Lymphocytes; Chitosan; Chronic Disease; Coxsackievirus Infections; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Intestinal Mucosa; Mice, Inbred BALB C; Myocarditis; Myocardium; Vaccination; Vaccines, DNA

2015
Targeted delivery of NK007 to macrophages to treat colitis.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:7

    Topics: Alginates; Alkaloids; Animals; Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Chitosan; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Drug Delivery Systems; Glucuronic Acid; Hexuronic Acids; Indolizines; Macrophages; Mice; Pharmaceutical Preparations; Phenanthrenes

2015
Chitooligosaccharide Inhibits Scar Formation and Enhances Functional Recovery in a Mouse Model of Sciatic Nerve Injury.
    Molecular neurobiology, 2016, Volume: 53, Issue:4

    Topics: Animals; Axons; Cell Death; Chitin; Chitosan; Cicatrix; Collagen; Demyelinating Diseases; Disease Models, Animal; Fibroblasts; Male; Mice, Transgenic; Nerve Regeneration; Oligosaccharides; Recovery of Function; Reflex; Sciatic Nerve; Time Factors

2016
In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency.
    Nature biotechnology, 2015, Volume: 33, Issue:6

    Topics: Animals; Asthma; Chitosan; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Nanoparticles; Pulmonary Alveolar Proteinosis; Pulmonary Surfactant-Associated Protein B; RNA Editing; RNA, Messenger

2015
Chitosan/siCkip-1 biofunctionalized titanium implant for improved osseointegration in the osteoporotic condition.
    Scientific reports, 2015, Jun-04, Volume: 5

    Topics: Absorbable Implants; Animals; Biomarkers; Cell Line; Cell Proliferation; Chitosan; Disease Models, Animal; Female; Intracellular Signaling Peptides and Proteins; Mesenchymal Stem Cells; Osseointegration; Osteogenesis; Osteoporosis; Rats; RNA, Small Interfering; Time Factors; Titanium; X-Ray Microtomography

2015
Pharmacological evaluation of nasal delivery of selegiline hydrochloride-loaded thiolated chitosan nanoparticles for the treatment of depression.
    Artificial cells, nanomedicine, and biotechnology, 2016, Volume: 44, Issue:3

    Topics: Administration, Intranasal; Animals; Antidepressive Agents; Chitosan; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Nanoparticles; Rats; Rats, Wistar; Selegiline

2016
Chitosan-tripolyphosphate nanoparticles as Arrabidaea chica standardized extract carrier: synthesis, characterization, biocompatibility, and antiulcerogenic activity.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Animals; Bignoniaceae; Cell Survival; Cells, Cultured; Chitosan; Disease Models, Animal; Drug Carriers; Ethanol; Fibroblasts; Humans; Indomethacin; Male; Nanoparticles; Particle Size; Phytochemicals; Plant Extracts; Polyphosphates; Rats; Rats, Wistar; Skin; Stomach Ulcer

2015
A bilayer composite composed of TiO2-incorporated electrospun chitosan membrane and human extracellular matrix sheet as a wound dressing.
    Journal of biomaterials science. Polymer edition, 2015, Volume: 26, Issue:13

    Topics: Adipose Tissue; Animals; Bandages; Chitosan; Disease Models, Animal; Escherichia coli; Extracellular Matrix; Female; Fluorescent Antibody Technique; Humans; Microscopy, Electron, Scanning; Rats, Sprague-Dawley; Skin; Staphylococcus aureus; Titanium; Wound Healing

2015
Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis.
    PLoS pathogens, 2015, Volume: 11, Issue:6

    Topics: Animals; Antibodies, Protozoan; Chitosan; Disease Models, Animal; Drug Carriers; Drug Resistance; Electrophoretic Mobility Shift Assay; Female; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Nanoparticles; Pentamidine; Real-Time Polymerase Chain Reaction; Trypanocidal Agents; Trypanosomiasis, African

2015
Acceleration of skin regeneration in full-thickness burns by incorporation of bFGF-loaded alginate microspheres into a CMCS-PVA hydrogel.
    Journal of tissue engineering and regenerative medicine, 2017, Volume: 11, Issue:5

    Topics: Animals; Burns; Chitosan; Dermis; Disease Models, Animal; Fibroblast Growth Factor 2; Hydrogels; Male; Mice; Microspheres; NIH 3T3 Cells; Polyvinyl Alcohol; Rats; Rats, Sprague-Dawley; Wound Healing

2017
Chitosan prevents adhesion during rabbit flexor tendon repair via the sirtuin 1 signaling pathway.
    Molecular medicine reports, 2015, Volume: 12, Issue:3

    Topics: Acetylation; Animals; Apoptosis; Cell Survival; Chitosan; Disease Models, Animal; eIF-2 Kinase; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1beta; Male; Niacinamide; Primary Cell Culture; Rabbits; Signal Transduction; Sirtuin 1; Tendon Injuries; Tendons; Tissue Adhesions; Tumor Suppressor Protein p53; Wound Healing

2015
Enhanced Neuroprotection of Acetyl-11-Keto-β-Boswellic Acid (AKBA)-Loaded O-Carboxymethyl Chitosan Nanoparticles Through Antioxidant and Anti-Inflammatory Pathways.
    Molecular neurobiology, 2016, Volume: 53, Issue:6

    Topics: Administration, Intravenous; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cells, Cultured; Chitosan; Disease Models, Animal; Glucose; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Interleukin-1beta; L-Lactate Dehydrogenase; Nanoparticles; Neurons; Neuroprotection; Neuroprotective Agents; Oxygen; Rats, Sprague-Dawley; Superoxide Dismutase; Tissue Distribution; Triterpenes; Tumor Necrosis Factor-alpha

2016
Incorporation of aligned PCL-PEG nanofibers into porous chitosan scaffolds improved the orientation of collagen fibers in regenerated periodontium.
    Acta biomaterialia, 2015, Volume: 25

    Topics: Animals; Calcification, Physiologic; Cell Adhesion; Cell Shape; Cell Survival; Chitosan; Collagen; Disease Models, Animal; Female; Gene Expression Regulation; Nanofibers; Osteogenesis; Periodontal Ligament; Periodontium; Polyesters; Polyethylene Glycols; Porosity; Rats, Sprague-Dawley; Regeneration; Tissue Scaffolds

2015
Effects of local application of methylprednisolone delivered by the C/GP-hydrogel on the recovery of facial nerves.
    Acta oto-laryngologica, 2015, Volume: 135, Issue:11

    Topics: Administration, Topical; Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Drug Carriers; Facial Nerve; Facial Nerve Injuries; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; Methylprednisolone; Microscopy, Electron, Scanning; Nerve Regeneration; Neuroprotective Agents; Rats; Rats, Wistar

2015
S-maltoheptaose targets syndecan-bound effectors to reduce smoking-related neutrophilic inflammation.
    Scientific reports, 2015, Aug-10, Volume: 5

    Topics: Aged; alpha 1-Antitrypsin; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Case-Control Studies; Chemokine CXCL1; Chitosan; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Glucans; Heparitin Sulfate; Humans; Inflammation; Inflammation Mediators; Leukocyte Elastase; Male; Middle Aged; Neutrophils; Peroxidase; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Smoking; Syndecan-1

2015
Evaluation of Chitosan/Aptamer Targeting TGF-β Receptor II Thermo-Sensitive Gel for Scarring in Rat Glaucoma Filtration Surgery.
    Investigative ophthalmology & visual science, 2015, Volume: 56, Issue:9

    Topics: Administration, Topical; Animals; Aptamers, Nucleotide; Biocompatible Materials; Blotting, Western; Chitosan; Cicatrix; Conjunctiva; Disease Models, Animal; DNA; Down-Regulation; Filtering Surgery; Gels; Glaucoma; In Situ Nick-End Labeling; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Wound Healing

2015
Sumatriptan succinate loaded chitosan solid lipid nanoparticles for enhanced anti-migraine potential.
    International journal of biological macromolecules, 2015, Volume: 81

    Topics: Animals; Behavior, Animal; Brain; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Drug Carriers; Drug Liberation; Male; Mice; Migraine Disorders; Nanoparticles; Rats; Serotonin 5-HT1 Receptor Agonists; Spectroscopy, Fourier Transform Infrared; Sumatriptan; Thermogravimetry; X-Ray Diffraction

2015
Sustained delivery of chondroitinase ABC by poly(propylene carbonate)-chitosan micron fibers promotes axon regeneration and functional recovery after spinal cord hemisection.
    Brain research, 2015, Oct-22, Volume: 1624

    Topics: Animals; Axons; Chitosan; Chondroitin ABC Lyase; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation; Motor Activity; Nerve Tissue Proteins; Propane; Rats; Rats, Wistar; Recovery of Function; Regeneration; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors

2015
Optimization and Evaluation of a Chitosan/Hydroxypropyl Methylcellulose Hydrogel Containing Toluidine Blue O for Antimicrobial Photodynamic Inactivation.
    International journal of molecular sciences, 2015, Sep-01, Volume: 16, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Hydrogel, Polyethylene Glycol Dimethacrylate; Hypromellose Derivatives; Microbial Sensitivity Tests; Photochemotherapy; Photosensitizing Agents; Pseudomonas aeruginosa; Rats; Staphylococcal Infections; Staphylococcus aureus; Tolonium Chloride; Viscosity

2015
Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:9

    Topics: Administration, Oral; Albendazole; Animals; Anthelmintics; Chitosan; Disease Models, Animal; Drug Carriers; Echinococcosis; Echinococcosis, Hepatic; Echinococcus multilocularis; Histocytochemistry; Liver; Male; Mice; Microspheres; Plasma; Treatment Outcome

2015
Efficacy study of two novel hyaluronic acid-based formulations for viscosupplementation therapy in an early osteoarthrosic rabbit model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 96

    Topics: Acetylation; Animals; Antioxidants; Bone and Bones; Cartilage; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Liberation; Hyaluronic Acid; Hydrogels; Knee Joint; Male; Osteoarthritis, Knee; Rabbits; Random Allocation; Resorcinols; Synovial Membrane; Viscosupplements

2015
Repair and regeneration of lumbosacral nerve defects in rats with chitosan conduits containing bone marrow mesenchymal stem cells.
    Injury, 2015, Volume: 46, Issue:11

    Topics: Animals; Bone Marrow Cells; Chitosan; Coated Materials, Biocompatible; Disease Models, Animal; Guided Tissue Regeneration; Mesenchymal Stem Cell Transplantation; Motor Activity; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Nerve

2015
Thermosensitive chitosan-based hydrogels for sustained release of ferulic acid on corneal wound healing.
    Carbohydrate polymers, 2016, Jan-01, Volume: 135

    Topics: Animals; Antioxidants; Apoptosis; Burns, Chemical; Cell Line; Cell Survival; Chitosan; Cornea; Coumaric Acids; Delayed-Action Preparations; Disease Models, Animal; Drug Liberation; Epithelial Cells; Eye Burns; Hydrogels; Hydrogen Peroxide; Rabbits; Sodium Hydroxide; Temperature; Wound Healing

2016
Dressing with epigallocatechin gallate nanoparticles for wound regeneration.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2016, Volume: 24, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bandages; Biocompatible Materials; Catechin; Cells, Cultured; Chitosan; Disease Models, Animal; Drug Delivery Systems; Fibroblasts; Gelatin; Gentamicins; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; Materials Testing; Nanoparticles; Polyglutamic Acid; Rats; Rats, Sprague-Dawley; Re-Epithelialization; Wound Healing; Wounds and Injuries

2016
PolySTAT-modified chitosan gauzes for improved hemostasis in external hemorrhage.
    Acta biomaterialia, 2016, Volume: 31

    Topics: Animals; Arterial Pressure; Bandages; Biopolymers; Blood Coagulation; Cell Adhesion; Chitosan; Cross-Linking Reagents; Disease Models, Animal; Erythrocyte Membrane; Erythrocytes; Femoral Artery; Fibrin; Hemorrhage; Hemostasis; Hemostatics; Polymers; Porosity; Rats

2016
Chitosan oligosaccharides alleviate cognitive deficits in an amyloid-β1-42-induced rat model of Alzheimer's disease.
    International journal of biological macromolecules, 2016, Volume: 83

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Avoidance Learning; Chitosan; Cognition; Disease Models, Animal; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Maze Learning; Neurons; Oligosaccharides; Oxidative Stress; Peptide Fragments; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2016
Improved bioavailability of targeted Curcumin delivery efficiently regressed cardiac hypertrophy by modulating apoptotic load within cardiac microenvironment.
    Toxicology and applied pharmacology, 2016, Jan-01, Volume: 290

    Topics: Acetylation; Animals; Apoptosis; bcl-2-Associated X Protein; Biological Availability; Cardiomegaly; Caspase 3; Cell Survival; Chitosan; Curcumin; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Delivery Systems; E1A-Associated p300 Protein; Myocardium; Myocytes, Cardiac; Nanoparticles; Rats; Rats, Wistar; Tumor Suppressor Protein p53

2016
Prawn Shell Chitosan Has Anti-Obesogenic Properties, Influencing Both Nutrient Digestibility and Microbial Populations in a Pig Model.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Animal Shells; Animals; Body Weight; Chitosan; Dietary Supplements; Disease Models, Animal; Eating; Gastrointestinal Tract; Leptin; Microbiota; Nephropidae; Obesity; Swine

2015
Protective effects of alginate-chitosan microspheres loaded with alkaloids from Coptis chinensis Franch. and Evodia rutaecarpa (Juss.) Benth. (Zuojin Pill) against ethanol-induced acute gastric mucosal injury in rats.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Adhesiveness; Alginates; Alkaloids; Animals; Anti-Ulcer Agents; Chemistry, Pharmaceutical; Chitosan; Coptis; Cytoprotection; Disease Models, Animal; Drug Carriers; Drugs, Chinese Herbal; Ethanol; Evodia; Gastric Mucosa; Glucuronic Acid; Hexuronic Acids; Inflammation Mediators; Interleukin-1beta; Male; Mice, Inbred ICR; Microspheres; Nitric Oxide Synthase Type II; Phytotherapy; Plants, Medicinal; Rats, Sprague-Dawley; Solubility; Stomach Ulcer; Time Factors; Tumor Necrosis Factor-alpha

2015
Chitosan Oligosaccharide Reduces Intestinal Inflammation That Involves Calcium-Sensing Receptor (CaSR) Activation in Lipopolysaccharide (LPS)-Challenged Piglets.
    Journal of agricultural and food chemistry, 2016, Jan-13, Volume: 64, Issue:1

    Topics: Animals; Chitosan; Disease Models, Animal; Female; Humans; Intestinal Diseases; Intestines; Lipopolysaccharides; Male; Oligosaccharides; Receptors, Calcium-Sensing; Swine

2016
Echogenic Glycol Chitosan Nanoparticles for Ultrasound-Triggered Cancer Theranostics.
    Theranostics, 2015, Volume: 5, Issue:12

    Topics: Animals; Chitosan; Disease Models, Animal; Male; Mice, Inbred BALB C; Mice, Inbred C3H; Nanoparticles; Neoplasms; Theranostic Nanomedicine; Ultrasonography

2015
Long-Term Feeding of Chitosan Ameliorates Glucose and Lipid Metabolism in a High-Fructose-Diet-Impaired Rat Model of Glucose Tolerance.
    Marine drugs, 2015, Dec-10, Volume: 13, Issue:12

    Topics: Animals; Blood Glucose; Chitosan; Dietary Carbohydrates; Dietary Supplements; Disease Models, Animal; Fructose; Glucose Intolerance; Lipid Metabolism; Male; Rats; Rats, Sprague-Dawley; Time Factors

2015
Polymicrobial Biofilm Inhibition Effects of Acetate-Buffered Chitosan Sponge Delivery Device.
    Macromolecular bioscience, 2016, Volume: 16, Issue:4

    Topics: Acetates; Amikacin; Animals; Anti-Bacterial Agents; Biofilms; Catheter-Related Infections; Catheters; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Drug Liberation; Freeze Drying; Humans; Mice; Polytetrafluoroethylene; Pseudomonas aeruginosa; Skin; Staphylococcus aureus; Vancomycin

2016
Sustained Nitric Oxide-Releasing Nanoparticles Induce Cell Death in Candida albicans Yeast and Hyphal Cells, Preventing Biofilm Formation In Vitro and in a Rodent Central Venous Catheter Model.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:4

    Topics: Animals; Antifungal Agents; Apoptosis; Biofilms; Candida albicans; Candidiasis; Catheter-Related Infections; Catheterization, Central Venous; Chitosan; Disease Models, Animal; Drug Therapy, Combination; Female; Fluconazole; Fungal Polysaccharides; Hyphae; Microbial Sensitivity Tests; Microbial Viability; Nanoparticles; Nitric Oxide; Nitric Oxide Donors; Organosilicon Compounds; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Voriconazole

2016
Effect of Plasma Sterilization on the Hemostatic Efficacy of a Chitosan Hemostatic Agent in a Rat Model.
    Advances in therapy, 2016, Volume: 33, Issue:2

    Topics: Animals; Bandages; Chitosan; Disease Models, Animal; Femoral Artery; Hemorrhage; Hemostatics; Rats; Sterilization; United States; Wounds and Injuries

2016
Postoperative anti-adhesion ability of a novel carboxymethyl chitosan from silkworm pupa in a rat cecal abrasion model.
    Materials science & engineering. C, Materials for biological applications, 2016, Apr-01, Volume: 61

    Topics: Animals; Bombyx; Cecum; Chitosan; Cytokines; Disease Models, Animal; Hydroxyproline; Leukocytes; Male; Pupa; Rats; Rats, Sprague-Dawley; Tissue Adhesions

2016
Use of photodynamic therapy and chitosan for inactivacion of Candida albicans in a murine model.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016, Volume: 45, Issue:8

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis, Oral; Chitosan; Disease Models, Animal; Epithelium; Female; Methylene Blue; Mice; Mice, Inbred DBA; Mucous Membrane; Nystatin; Photochemotherapy; Photosensitizing Agents; Random Allocation

2016
Folate-modified Chitosan Nanoparticles Containing the IP-10 Gene Enhance Melanoma-specific Cytotoxic CD8(+)CD28(+) T Lymphocyte Responses.
    Theranostics, 2016, Volume: 6, Issue:5

    Topics: Adoptive Transfer; Animals; CD28 Antigens; CD8-Positive T-Lymphocytes; Chemokine CXCL10; Chitosan; Cytotoxicity, Immunologic; Disease Models, Animal; Drug Carriers; Folic Acid; Melanoma; Mice; Nanoparticles; Survival Analysis; Treatment Outcome

2016
Chitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-κB and mTOR signaling.
    Carbohydrate polymers, 2016, 07-10, Volume: 145

    Topics: AMP-Activated Protein Kinases; Animals; Anticarcinogenic Agents; Chitosan; Colitis; Colon; Colorectal Neoplasms; Cyclin D1; Disease Models, Animal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; NF-kappa B; Oligosaccharides; TOR Serine-Threonine Kinases; Tumor Burden

2016
Active nano/microbilayer hemostatic agents for diabetic rat bleeding model.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2017, Volume: 105, Issue:6

    Topics: Animals; Bandages; Cellulose; Chitosan; Disease Models, Animal; Female; Femoral Artery; Fibroins; Hemorrhage; Hemostatics; Kaolin; Protamines; Rats; Rats, Sprague-Dawley

2017
Ceria-containing uncoated and coated hydroxyapatite-based galantamine nanocomposites for formidable treatment of Alzheimer's disease in ovariectomized albino-rat model.
    Materials science & engineering. C, Materials for biological applications, 2016, Aug-01, Volume: 65

    Topics: Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cerebral Cortex; Cerium; Chitosan; Chlorides; Disease Models, Animal; Drug Carriers; Durapatite; Dynamic Light Scattering; Female; Galantamine; Hippocampus; Nanocomposites; Ovariectomy; Rats; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2016
Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth.
    Theranostics, 2016, Volume: 6, Issue:6

    Topics: Albumins; Alopecia; Animals; Chitosan; Disease Models, Animal; Drug Delivery Systems; Hair; Mice, Inbred C57BL; Microbubbles; Minoxidil; Sonication; Treatment Outcome; Vasodilator Agents

2016
Ultrasonographical assessment of implanted biodegradable device for long-term slow release of methotrexate into the vitreous.
    Experimental eye research, 2016, Volume: 148

    Topics: Absorbable Implants; Animals; Biocompatible Materials; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Delivery Systems; Immunosuppressive Agents; Methotrexate; Polyesters; Rabbits; Retina; Ultrasonography; Vitreous Body

2016
Nanoencapsulation of Red Ginseng Extracts Using Chitosan with Polyglutamic Acid or Fucoidan for Improving Antithrombotic Activities.
    Journal of agricultural and food chemistry, 2016, Jun-15, Volume: 64, Issue:23

    Topics: Animals; Chitosan; Disease Models, Animal; Drug Carriers; Fibrinolytic Agents; Male; Mice, Inbred ICR; Nanoparticles; Panax; Plant Extracts; Platelet Aggregation; Polyglutamic Acid; Polysaccharides; Rabbits; Rats, Sprague-Dawley; Thrombosis

2016
Chitosan Promoted the Corneal Epithelial Wound Healing via Activation of ERK Pathway.
    Current eye research, 2017, Volume: 42, Issue:1

    Topics: Animals; Blotting, Western; Cell Migration Assays; Cell Movement; Cell Proliferation; Cells, Cultured; Chitosan; Corneal Injuries; Disease Models, Animal; Epithelium, Corneal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluorescent Antibody Technique, Indirect; Ki-67 Antigen; Organ Culture Techniques; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Rabbits; Wound Healing

2017
Combined Near Infrared Photothermal Therapy and Chemotherapy Using Gold Nanoshells Coated Liposomes to Enhance Antitumor Effect.
    Small (Weinheim an der Bergstrasse, Germany), 2016, Volume: 12, Issue:30

    Topics: Animals; Antineoplastic Agents; Chitosan; Disease Models, Animal; Female; Gold; Hydrogen-Ion Concentration; Hyperthermia, Induced; Liposomes; Mice; Nanoshells; Oleanolic Acid; Spectroscopy, Fourier Transform Infrared

2016
Effects of Medical Chitosan on Capsular Formation Following Silicone Implant Insertion in a Rabbit Model.
    Aesthetic plastic surgery, 2016, Volume: 40, Issue:4

    Topics: Animals; Blotting, Western; Breast Implantation; Breast Implants; Chitosan; Disease Models, Animal; Female; Immunohistochemistry; Implant Capsular Contracture; Prosthesis Design; Rabbits; Random Allocation; Real-Time Polymerase Chain Reaction; Reference Values; Silicone Gels

2016
Phenylboronic Acid-Mediated Tumor Targeting of Chitosan Nanoparticles.
    Theranostics, 2016, Volume: 6, Issue:9

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Cell Line, Tumor; Chemical Phenomena; Chitosan; Disease Models, Animal; Doxorubicin; Drug Carriers; Dynamic Light Scattering; Heterografts; Mice; Microscopy, Electron, Transmission; Nanoparticles; Neuroblastoma; Spheroids, Cellular; Survival Analysis; Treatment Outcome

2016
Zwitterionic chitosan for the systemic treatment of sepsis.
    Scientific reports, 2016, 07-14, Volume: 6

    Topics: Animals; Cell Line; Chemokine CXCL2; Chitosan; Disease Models, Animal; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Sepsis

2016
The effect of chitosan-based gel on second degree burn wounds.
    Journal of wound care, 2016, Volume: 25, Issue:8

    Topics: Animals; Burns; Chitosan; Disease Models, Animal; Gels; Humans; Rabbits; Wound Healing

2016
Asymmetric Collagen/chitosan Membrane Containing Minocycline-loaded Chitosan Nanoparticles for Guided Bone Regeneration.
    Scientific reports, 2016, 08-22, Volume: 6

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bone Regeneration; Chitosan; Collagen; Disease Models, Animal; Fibroblasts; Guided Tissue Regeneration; Male; Materials Testing; Membranes, Artificial; Minocycline; Nanoparticles; Osteoblasts; Rats; Rats, Sprague-Dawley

2016
Multi-cycle chemotherapy with the glycolipid-like polymeric micelles evade cancer stem cell enrichment in breast cancer therapy.
    Oncotarget, 2016, Nov-08, Volume: 7, Issue:45

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chitosan; Disease Models, Animal; Doxorubicin; Female; Glycolipids; Humans; Mice; Micelles; Neoplastic Stem Cells; Polymers; Spheroids, Cellular; Treatment Outcome; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays

2016
Extended wear therapeutic contact lens fabricated from timolol imprinted carboxymethyl chitosan-g-hydroxy ethyl methacrylate-g-poly acrylamide as a onetime medication for glaucoma.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 109

    Topics: Animals; Anti-Infective Agents; Cell Line; Cell Survival; Chitosan; Contact Lenses; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Elastic Modulus; Escherichia coli; Glaucoma; Humans; Kinetics; Methacrylates; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; Tears; Timolol

2016
Application of chitosan microparticles for treatment of metritis and in vivo evaluation of broad spectrum antimicrobial activity in cow uteri.
    Biomaterials, 2016, Volume: 110

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteroidaceae Infections; Cattle; Cephalosporins; Chitosan; Disease Models, Animal; Female; Fusobacteriaceae Infections; Fusobacterium necrophorum; Humans; Treatment Outcome; Uterine Diseases; Uterus

2016
Development and Characterization of VEGF165-Chitosan Nanoparticles for the Treatment of Radiation-Induced Skin Injury in Rats.
    Marine drugs, 2016, Oct-11, Volume: 14, Issue:10

    Topics: Administration, Cutaneous; Animals; Chitosan; Disease Models, Animal; Male; Nanoparticles; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Skin; Vascular Endothelial Growth Factor A

2016
Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses.
    BMC immunology, 2016, 10-18, Volume: 17, Issue:1

    Topics: Animals; Antigen Presentation; Cancer Vaccines; Carcinogenesis; CD8-Positive T-Lymphocytes; Cecum; Cell Growth Processes; Chitosan; Cytotoxicity, Immunologic; Dendritic Cells; Disease Models, Animal; Gels; Humans; Immunity, Humoral; Immunologic Memory; Immunotherapy, Adoptive; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Vaccination

2016
Use of 5-Fluorouracil Loaded Micelles and Cisplatin in Thermosensitive Chitosan Hydrogel as an Efficient Therapy against Colorectal Peritoneal Carcinomatosis.
    Macromolecular bioscience, 2017, Volume: 17, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Chitosan; Cisplatin; Colorectal Neoplasms; Disease Models, Animal; Drug Liberation; Female; Fluorouracil; Hydrogel, Polyethylene Glycol Dimethacrylate; Immunohistochemistry; Injections; Ki-67 Antigen; Liver Neoplasms; Lung Neoplasms; Mice, Inbred BALB C; Micelles; Peritoneal Neoplasms; Rheology; Temperature

2017
Sustained Nitric Oxide-Releasing Nanoparticles Interfere with Methicillin-Resistant Staphylococcus aureus Adhesion and Biofilm Formation in a Rat Central Venous Catheter Model.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Catheter-Related Infections; Central Venous Catheters; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Female; Glucose; Humans; Methicillin-Resistant Staphylococcus aureus; Nanoparticles; Nitric Oxide; Oxidation-Reduction; Plankton; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Staphylococcal Infections

2017
Co-delivery of zinc and 5-aminosalicylic acid from alginate/N-succinyl-chitosan blend microspheres for synergistic therapy of colitis.
    International journal of pharmaceutics, 2017, Jan-10, Volume: 516, Issue:1-2

    Topics: Administration, Oral; Alginates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Colitis; Disease Models, Animal; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Synergism; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Male; Mesalamine; Microscopy, Electron, Scanning; Microspheres; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Zinc

2017
Influenza H7N9 LAH-HBc virus-like particle vaccine with adjuvant protects mice against homologous and heterologous influenza viruses.
    Vaccine, 2016, 12-12, Volume: 34, Issue:51

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Viral; Chitosan; Cross Protection; Disease Models, Animal; Drug Carriers; Epitopes; Escherichia coli; Female; Hemagglutinin Glycoproteins, Influenza Virus; Hepatitis B Core Antigens; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H7N9 Subtype; Influenza Vaccines; Leukocytes, Mononuclear; Mice, Inbred BALB C; Orthomyxoviridae Infections; Recombinant Fusion Proteins; Vaccines, Synthetic; Vaccines, Virus-Like Particle

2016
Peritoneal adhesion prevention with a biodegradable and injectable N,O-carboxymethyl chitosan-aldehyde hyaluronic acid hydrogel in a rat repeated-injury model.
    Scientific reports, 2016, 11-21, Volume: 6

    Topics: Animals; Biocompatible Materials; Cell Death; Cell Survival; Chitosan; Disease Models, Animal; Fibroblasts; Hyaluronic Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Injections; Male; Mice; NIH 3T3 Cells; Oxidation-Reduction; Peritoneum; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Rheology; Tissue Adhesions; Tissue Plasminogen Activator

2016
Chitosan nanoparticles as a dual drug/siRNA delivery system for treatment of colorectal cancer.
    Immunology letters, 2017, Volume: 181

    Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Chitosan; Colorectal Neoplasms; Disease Models, Animal; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Humans; Mice; Nanoparticles; RNA, Small Interfering; Spectroscopy, Fourier Transform Infrared; Wound Healing; Xenograft Model Antitumor Assays

2017
Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats.
    Acta cirurgica brasileira, 2016, Volume: 31, Issue:12

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Chitosan; Disease Models, Animal; Ethanol; Gastric Mucosa; Hydroxyproline; Ink; Malondialdehyde; Molecular Weight; Random Allocation; Rats; Sepia; Stomach Ulcer

2016
Chitosan-Sodium Tetradecyl Sulfate Hydrogel: Characterization and Preclinical Evaluation of a Novel Sclerosing Embolizing Agent for the Treatment of Endoleaks.
    Cardiovascular and interventional radiology, 2017, Volume: 40, Issue:4

    Topics: Animals; Chitosan; Disease Models, Animal; Dogs; Embolization, Therapeutic; Endoleak; Endovascular Procedures; Hydrogels; Sclerosing Solutions; Sodium Tetradecyl Sulfate

2017
Full-Thickness Heart Repair with an Engineered Multilayered Myocardial Patch in Rat Model.
    Advanced healthcare materials, 2017, Volume: 6, Issue:5

    Topics: Animals; Chitosan; Disease Models, Animal; Female; Hydrogels; Male; Materials Testing; Membranes, Artificial; Myocardium; Pericardium; Polyesters; Rats; Rats, Sprague-Dawley

2017
Blended Chitosan Paste for Infection Prevention: Preliminary and Preclinical Evaluations.
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Chitosan; Disease Models, Animal; Drug Carriers; Drug Combinations; In Vitro Techniques; Mice; Polyethylene Glycols; Prosthesis-Related Infections; Pseudomonas aeruginosa; Staphylococcus aureus

2017
The Influence of Chitosan Cross-linking on the Properties of Alginate Microparticles with Metformin Hydrochloride-In Vitro and In Vivo Evaluation.
    Molecules (Basel, Switzerland), 2017, Jan-22, Volume: 22, Issue:1

    Topics: Alginates; Animals; Blood Glucose; Chemistry, Pharmaceutical; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Drug Carriers; Drug Compounding; Glucuronic Acid; Hexuronic Acids; Kidney; Liver; Male; Metformin; Pancreas; Particle Size; Rats; Rats, Wistar; Streptozocin

2017
Alkyl polyglycoside, a highly promising adjuvant in intranasal split influenza vaccines.
    Human vaccines & immunotherapeutics, 2017, 06-03, Volume: 13, Issue:6

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Neutralizing; Antibodies, Viral; Chitosan; Disease Models, Animal; Female; Glycosides; Hemagglutination Inhibition Tests; Immunity, Mucosal; Immunoglobulin A; Immunoglobulin G; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza Vaccines; Injections, Intramuscular; Lung; Mice, Inbred BALB C; Nasal Mucosa; Orthomyxoviridae Infections; Polymers; Polysaccharides, Bacterial; Survival Analysis; Treatment Outcome; Vaccines, Inactivated

2017
Biocompatible biodegradable polymeric antibacterial nanoparticles for enhancing the effects of a third-generation cephalosporin against resistant bacteria.
    Journal of medical microbiology, 2017, Volume: 66, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Ceftriaxone; Chitosan; Disease Models, Animal; Drug Synergism; Escherichia coli; Escherichia coli Infections; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Microbial Viability; Nanoparticles; Neutropenia; Staphylococcal Infections

2017
Ectopic expression of SIGIRR in the colon ameliorates colitis in mice by downregulating TLR4/NF-κB overactivation.
    Immunology letters, 2017, Volume: 183

    Topics: Animals; Chitosan; Colitis; Disease Models, Animal; Ectopic Gene Expression; Gene Expression Regulation; Gene Transfer Techniques; Intestinal Mucosa; Mice; Myeloid Differentiation Factor 88; Nanoparticles; NF-kappa B; Receptors, Interleukin-1; Signal Transduction; Toll-Like Receptor 4

2017
Investigating the potential of Tamarindus indica pectin-chitosan conjugate for reducing recovery period in TNBS induced colitis.
    International journal of biological macromolecules, 2017, Volume: 98

    Topics: Animals; Chitosan; Colitis; Disease Models, Animal; Drug Delivery Systems; Humans; Pectins; Plant Exudates; Rats; Tablets; Tamarindus; Trinitrobenzenesulfonic Acid; Wound Healing

2017
Supramolecular Chitosan Micro-Platelets Synergistically Enhance Anti-Candida albicans Activity of Amphotericin B Using an Immunocompetent Murine Model.
    Pharmaceutical research, 2017, Volume: 34, Issue:5

    Topics: alpha-Cyclodextrins; Amphotericin B; Animals; Antifungal Agents; Blood Platelets; Candida albicans; Candidiasis; Chemistry, Pharmaceutical; Chitosan; Deoxycholic Acid; Disease Models, Animal; Drug Combinations; Female; Hydrogels; Mice; Mice, Inbred BALB C; Mucous Membrane; Nanoparticles; Poloxamer; Swine

2017
The effects of CpG-ODNs and Chitosan adjuvants on the elicitation of immune responses induced by the HIV-1-Tat-based candidate vaccines in mice.
    Pathogens and disease, 2017, 03-01, Volume: 75, Issue:2

    Topics: Adjuvants, Immunologic; AIDS Vaccines; Animals; Chitosan; Cytotoxicity, Immunologic; Disease Models, Animal; Female; HIV Antibodies; HIV Infections; HIV-1; Immunization; Interferon-gamma; Lymphocyte Activation; Lymphocytes; Mice; Oligodeoxyribonucleotides; Recombinant Proteins; tat Gene Products, Human Immunodeficiency Virus

2017
Omp16-based vaccine encapsulated by alginate-chitosan microspheres provides significant protection against Haemophilus parasuis in mice.
    Vaccine, 2017, 03-07, Volume: 35, Issue:10

    Topics: Alginates; Animal Structures; Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Load; Bacterial Outer Membrane Proteins; Chitosan; Cytokines; Disease Models, Animal; Drug Carriers; Glucuronic Acid; Haemophilus Infections; Haemophilus parasuis; Haemophilus Vaccines; Hexuronic Acids; Immunity, Cellular; Immunity, Humoral; Leukocytes, Mononuclear; Mice, Inbred BALB C; Microspheres; Survival Analysis; Swine; Swine Diseases; Treatment Outcome; Vaccines, Subunit

2017
Evaluation of surgical anti-adhesion products to reduce postsurgical intra-abdominal adhesion formation in a rat model.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Abdominal Wall; Animals; Biocompatible Materials; Cecum; Chitosan; Disease Models, Animal; Female; Hyaluronic Acid; Polyesters; Postoperative Complications; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Wound Healing

2017
Multifunctional biocompatible chitosan-polypyrrole nanocomposites as novel agents for photoacoustic imaging-guided photothermal ablation of cancer.
    Scientific reports, 2017, 03-02, Volume: 7

    Topics: Animals; Cell Line, Tumor; Chitosan; Disease Models, Animal; Female; Humans; Hyperthermia, Induced; Mice; Nanocomposites; Neoplasms; Photoacoustic Techniques; Phototherapy; Polymers; Pyrroles; Xenograft Model Antitumor Assays

2017
Chitosan nerve conduits seeded with autologous bone marrow mononuclear cells for 30 mm goat peroneal nerve defect.
    Scientific reports, 2017, 03-13, Volume: 7

    Topics: Animals; Behavior, Animal; Biocompatible Materials; Bone Marrow; Cell Transplantation; Chitosan; Disease Models, Animal; Goats; Histocytochemistry; Magnetic Resonance Imaging; Peripheral Nervous System Diseases; Peroneal Nerve; Treatment Outcome

2017
Chitosan Wound Dressings Incorporating Exosomes Derived from MicroRNA-126-Overexpressing Synovium Mesenchymal Stem Cells Provide Sustained Release of Exosomes and Heal Full-Thickness Skin Defects in a Diabetic Rat Model.
    Stem cells translational medicine, 2017, Volume: 6, Issue:3

    Topics: Animals; Bandages; Cell Proliferation; Chitosan; Delayed-Action Preparations; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelial Cells; Exosomes; Fibroblasts; Humans; Male; Mesenchymal Stem Cells; MicroRNAs; Rats, Sprague-Dawley; Skin; Synovial Membrane; Wound Healing; X-Ray Microtomography

2017
A novel biodegradable delivery system for bone morphogenetic protein-2.
    Plastic and reconstructive surgery, 2008, Volume: 121, Issue:6

    Topics: Absorbable Implants; Animals; Biocompatible Materials; Biopsy, Needle; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Heparin; Immunohistochemistry; Implants, Experimental; Male; Osteogenesis; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Transforming Growth Factor beta

2008
Laparoscopic repair of inferior vena caval injury using a chitosan-based hemostatic dressing.
    American journal of surgery, 2009, Volume: 197, Issue:4

    Topics: Animals; Bandages; Blood Loss, Surgical; Chitosan; Disease Models, Animal; Hemorrhage; Hemostasis, Surgical; Hemostatics; Laparoscopy; Swine; Vena Cava, Inferior

2009
Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Dec-18, Volume: 132, Issue:3

    Topics: Administration, Oral; Animals; Chitosan; Disease Models, Animal; DNA; Dogs; Factor VIII; Feasibility Studies; Genetic Therapy; Hemophilia A; Hemostasis; Humans; Mice; Mice, Knockout; Nanoparticles; Thrombin; Time Factors; Tissue Distribution; Transfection

2008
Chitosan ameliorates the severity of steatohepatitis induced by high fat diet in rats.
    Scandinavian journal of gastroenterology, 2008, Volume: 43, Issue:11

    Topics: Animals; Anticholesteremic Agents; Chitosan; Dietary Fats; Disease Models, Animal; Fatty Liver; Male; Rats; Rats, Sprague-Dawley; Treatment Outcome

2008
IFATS collection: Human adipose-derived stem cells seeded on a silk fibroin-chitosan scaffold enhance wound repair in a murine soft tissue injury model.
    Stem cells (Dayton, Ohio), 2009, Volume: 27, Issue:1

    Topics: Adipose Tissue; Animals; Biopsy; Chitosan; Dermatologic Surgical Procedures; Disease Models, Animal; Fibroins; Fluorescent Antibody Technique; Mice; Regeneration; Silk; Skin; Stem Cell Transplantation; Stem Cells; Tissue Scaffolds; Wound Healing

2009
A novel highly porous silica and chitosan-based hemostatic dressing is superior to HemCon and gauze sponges.
    The Journal of trauma, 2008, Volume: 65, Issue:4

    Topics: Animals; Blood Loss, Surgical; Chi-Square Distribution; Chitosan; Disease Models, Animal; Female; Femoral Vein; Fibrin Tissue Adhesive; Hemorrhage; Hemostatic Techniques; Hemostatics; Male; Occlusive Dressings; Probability; Random Allocation; Risk Factors; Sensitivity and Specificity; Silicon Dioxide; Statistics, Nonparametric; Swine

2008
[Therapeutic effects of chitosan/polyethylene glycols-succinate/mitomycin C film drug delivery system on epidural scarring tissues after laminectomy of SD rats].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:10

    Topics: Animals; Biocompatible Materials; Chitosan; Cicatrix; Disease Models, Animal; Drug Delivery Systems; Epidural Space; Laminectomy; Male; Mitomycin; Polyethylenes; Postoperative Complications; Rats; Rats, Sprague-Dawley; Succinates

2008
[Preliminary study on chitosan/HAP bilayered scaffold].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:11

    Topics: Animals; Bone Marrow Cells; Bone Regeneration; Bone Substitutes; Cartilage, Articular; Cell Culture Techniques; Cells, Cultured; Chitosan; Chondrocytes; Disease Models, Animal; Rabbits; Stromal Cells; Tissue Engineering; Tissue Scaffolds

2008
The effect of a layer-by-layer chitosan-heparin coating on the endothelialization and coagulation properties of a coronary stent system.
    Biomaterials, 2009, Volume: 30, Issue:12

    Topics: Animals; Blood Coagulation; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Chitosan; Coronary Vessels; Disease Models, Animal; Endothelial Cells; Heparin; Microscopy, Electron, Scanning; Models, Biological; Stents; Swine

2009
Effect of Asparagus racemosus extract on transdermal delivery of carvedilol: a mechanistic study.
    AAPS PharmSciTech, 2009, Volume: 10, Issue:1

    Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Asparagus Plant; Blood Pressure; Carbazoles; Carvedilol; Chemistry, Pharmaceutical; Chitosan; Cholesterol; Delayed-Action Preparations; Desoxycorticosterone; Disease Models, Animal; Drug Compounding; Epidermis; Female; Hypertension; Male; Permeability; Plant Extracts; Plant Roots; Propanolamines; Rats; Rats, Wistar; Saponins; Skin Absorption; Sphingosine; Technology, Pharmaceutical; Time Factors; Triglycerides

2009
[BMSCs-chitosan hydrogel complex transplantation for treating intervertebral disc degeneration].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2009, Volume: 23, Issue:2

    Topics: Animals; Bone Marrow Cells; Cell Transplantation; Chitosan; Disease Models, Animal; Hydrogel, Polyethylene Glycol Dimethacrylate; Intervertebral Disc; Intervertebral Disc Displacement; Rabbits; Tissue Engineering; Transplantation, Homologous

2009
Efficacy of three topical hemostatic agents applied by medics in a lethal groin injury model.
    The Journal of surgical research, 2009, Jun-15, Volume: 154, Issue:2

    Topics: Animals; Bandages; Chitosan; Disease Models, Animal; Femoral Artery; Goats; Groin; Hemorrhage; Hemostatic Techniques; Military Medicine; Powders; Wounds and Injuries

2009
Comparison of ChitoFlex®, CELOX™, and QuikClot® in control of hemorrhage.
    The Journal of emergency medicine, 2011, Volume: 41, Issue:3

    Topics: Animals; Bandages; Chitosan; Disease Models, Animal; Female; Groin; Hemorrhage; Hemostatics; Military Medicine; Prospective Studies; Random Allocation; Sus scrofa; Wounds and Injuries

2011
Effect of chitosan-N-acetylcysteine conjugate in a mouse model of botulinum toxin B-induced dry eye.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2009, Volume: 127, Issue:4

    Topics: Acetylcysteine; Administration, Topical; Animals; Blinking; Botulinum Toxins; Botulinum Toxins, Type A; Chitosan; Conjunctiva; Cornea; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Female; Fluorescent Antibody Technique, Indirect; Fluorometholone; Lacrimal Apparatus; Mice; Mice, Inbred CBA; Ophthalmic Solutions; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tears

2009
A highly porous silica and chitosan-based hemostatic dressing is superior in controlling hemorrhage in a severe groin injury model in swine.
    American journal of surgery, 2009, Volume: 197, Issue:5

    Topics: Animals; Chitosan; Disease Models, Animal; Groin; Hemostasis, Surgical; Hemostatics; Occlusive Dressings; Swine

2009
Local nasal immunotherapy: efficacy of Dermatophagoides farinae-chitosan vaccine in murine asthma.
    International archives of allergy and immunology, 2009, Volume: 150, Issue:3

    Topics: Administration, Intranasal; Animals; Antigens, Dermatophagoides; Asthma; Biocompatible Materials; Chitosan; Dermatophagoides farinae; Desensitization, Immunologic; Disease Models, Animal; Drug Delivery Systems; Female; Mice; Mice, Inbred BALB C; Nanospheres; Vaccines

2009
Transdermal delivery of carvedilol in rats: probing the percutaneous permeation enhancement mechanism of soybean extract-chitosan mixture.
    Drug development and industrial pharmacy, 2009, Volume: 35, Issue:10

    Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Desoxycorticosterone; Disease Models, Animal; Epidermis; Excipients; Female; Glycine max; Hypertension; Male; Permeability; Plant Extracts; Propanolamines; Rats; Rats, Wistar; Skin Absorption; Solubility

2009
[Study on repair of full-thickness skin defect with collagen-chitosan dermal stent in pigs].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2009, Feb-15, Volume: 47, Issue:4

    Topics: Animals; Chitosan; Collagen; Disease Models, Animal; Female; Graft Survival; Neovascularization, Physiologic; Silicones; Skin; Skin Transplantation; Swine; Swine, Miniature; Tissue Scaffolds; Wound Healing

2009
[Experimental study of the effect of chitosan/alginate dressings on wound immersed in seawater].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2009, Volume: 23, Issue:6

    Topics: Alginates; Animals; Bandages; Chitosan; Disease Models, Animal; ErbB Receptors; Female; Fibroblast Growth Factor 2; Glucuronic Acid; Hexuronic Acids; Male; Rats; Rats, Sprague-Dawley; Seawater; Skin; Wound Healing

2009
Chitooligosaccharides promote peripheral nerve regeneration in a rabbit common peroneal nerve crush injury model.
    Microsurgery, 2009, Volume: 29, Issue:8

    Topics: Animals; Chitosan; Disease Models, Animal; Nerve Crush; Nerve Regeneration; Neuroprotective Agents; Oligosaccharides; Peripheral Nerves; Rabbits; Random Allocation; Recovery of Function; Sciatic Nerve

2009
Embolization of a common carotid aneurysm with rhVEGF coupled to a pH-responsive chitosan in a rat model.
    Journal of neurosurgery, 2010, Volume: 112, Issue:3

    Topics: Animals; Biocompatible Materials; Brain; Carotid Artery Diseases; Carotid Artery, Common; Chitosan; Collagen; Disease Models, Animal; Elastin; Embolization, Therapeutic; Extracellular Matrix; Fibrosis; Hydrogen-Ion Concentration; Intracranial Aneurysm; Macrophages; Mitogens; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A

2010
Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Dec-03, Volume: 140, Issue:2

    Topics: Acetylation; Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Viral; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Drug Compounding; Female; Immunization Schedule; Immunoglobulin A, Secretory; Immunoglobulin G; Influenza A virus; Influenza Vaccines; Methylation; Mice; Mice, Inbred C57BL; Molecular Structure; Nasal Lavage Fluid; Orthomyxoviridae Infections; Structure-Activity Relationship; Time Factors; Vaccines, Inactivated

2009
Osteogenesis mechanism of chitosan-coated calcium sulfate pellets on the restoration of segmental bone defects.
    The Journal of craniofacial surgery, 2009, Volume: 20, Issue:5

    Topics: Absorbable Implants; Animals; Bone Density; Bone Diseases; Bone Marrow; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Bone Substitutes; Calcification, Physiologic; Calcium Sulfate; Chitosan; Coated Materials, Biocompatible; Connective Tissue; Diaphyses; Disease Models, Animal; Fluorescent Dyes; Fluorometry; Humans; Osteogenesis; Rabbits; Radius; Recombinant Proteins; Stress, Mechanical; Tetracycline; Time Factors; Transforming Growth Factor beta

2009
Use of a modified chitosan dressing in a hypothermic coagulopathic grade V liver injury model.
    American journal of surgery, 2009, Volume: 198, Issue:5

    Topics: Animals; Bandages; Blood Coagulation Disorders; Chitosan; Disease Models, Animal; Hemorrhage; Hemostatic Techniques; Hemostatics; Hypothermia; Liver; Swine

2009
Comment on "the effect of continuous release of recombinant human epidermal growth factor (rh-EGF) in chitosan film on full thickness excisional porcine wounds".
    Annals of plastic surgery, 2009, Volume: 63, Issue:4

    Topics: Animals; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Epidermal Growth Factor; Humans; Random Allocation; Recombinant Proteins; Swine; Wound Healing; Wounds and Injuries; Wounds, Penetrating

2009
Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model.
    Gastroenterology, 2010, Volume: 138, Issue:3

    Topics: Administration, Oral; Alginates; Animals; Anti-Inflammatory Agents; Caco-2 Cells; Chemistry, Pharmaceutical; Chitosan; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Female; Gastrointestinal Agents; Glucuronic Acid; Hexuronic Acids; Humans; Hydrogels; Intestinal Mucosa; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred C57BL; Nanoparticles; Peptide Fragments; Polysaccharides; Solubility; Time Factors

2010
Quality of newly formed cartilaginous tissue in defects of articular surface after transplantation of mesenchymal stem cells in a composite scaffold based on collagen I with chitosan micro- and nanofibres.
    Physiological research, 2010, Volume: 59, Issue:4

    Topics: Animals; Arthroplasty, Subchondral; Cartilage, Articular; Cells, Cultured; Chitosan; Chondrogenesis; Collagen Type I; Disease Models, Animal; Immunohistochemistry; Knee Injuries; Knee Joint; Mesenchymal Stem Cell Transplantation; Nanofibers; Swine; Swine, Miniature; Time Factors; Tissue Scaffolds; Wound Healing

2010
Bioefficacy of budesonide loaded crosslinked polyelectrolyte microparticles in rat model of induced colitis.
    Journal of drug targeting, 2009, Volume: 17, Issue:10

    Topics: Alginates; Animals; Anti-Inflammatory Agents; Budesonide; Calcium Chloride; Chitosan; Colitis; Cross-Linking Reagents; Delayed-Action Preparations; Disease Models, Animal; Drug Delivery Systems; Electrolytes; Glucuronic Acid; Hexuronic Acids; Male; Microspheres; Polymethacrylic Acids; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid

2009
Novel multifunctional polyethylene glycol-transactivating-transduction protein-modified liposomes cross the blood-spinal cord barrier after spinal cord injury.
    Journal of drug targeting, 2010, Volume: 18, Issue:6

    Topics: Animals; Chitosan; Cholesterol; Disease Models, Animal; Drug Delivery Systems; Gene Products, tat; Iron; Liposomes; Magnetic Resonance Imaging; Magnetics; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Peptide Fragments; Peptides; Polyethylene Glycols; Rats; Spectrophotometry, Atomic; Spinal Cord; Spinal Cord Injuries; Surface Properties

2010
Local controlled release of VEGF and PDGF from a combined brushite-chitosan system enhances bone regeneration.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Apr-02, Volume: 143, Issue:1

    Topics: Alginates; Animals; Bone Regeneration; Calcium Phosphates; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Compounding; Femur; Glucuronic Acid; Hexuronic Acids; Platelet-Derived Growth Factor; Porosity; Rabbits; Solubility; Technology, Pharmaceutical; Tissue Distribution; Tissue Scaffolds; Vascular Endothelial Growth Factor A

2010
Evaluation of novel vanilloid-based hemostatic agents in rats.
    The Journal of trauma, 2010, Volume: 68, Issue:3

    Topics: Administration, Topical; Animals; Bandages; Chitosan; Collagen; Disease Models, Animal; Femoral Artery; Hemostatics; Male; Powders; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; TRPV Cation Channels; Wounds, Penetrating

2010
Intranasal drug delivery of didanosine-loaded chitosan nanoparticles for brain targeting; an attractive route against infections caused by AIDS viruses.
    Journal of drug targeting, 2010, Volume: 18, Issue:5

    Topics: Administration, Intranasal; Animals; Brain; Chitosan; Chromatography, Liquid; Didanosine; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; HIV Infections; Male; Mass Spectrometry; Microscopy, Electron, Transmission; Nanoparticles; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors

2010
Reduction in postsurgical adhesion formation after cardiac surgery by application of N,O-carboxymethyl chitosan.
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 140, Issue:4

    Topics: Administration, Topical; Animals; Biocompatible Materials; Cardiac Surgical Procedures; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Female; Gels; Heart Diseases; Male; Rabbits; Severity of Illness Index; Swine; Time Factors; Tissue Adhesions

2010
Bone repair by cell-seeded 3D-bioplotted composite scaffolds made of collagen treated tricalciumphosphate or tricalciumphosphate-chitosan-collagen hydrogel or PLGA in ovine critical-sized calvarial defects.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2010, Volume: 93, Issue:2

    Topics: Absorbable Implants; Animals; Bone Regeneration; Calcium Phosphates; Chitosan; Collagen; Disease Models, Animal; Female; Glycolates; Hydrogels; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sheep; Skull; Time Factors; Tissue Scaffolds

2010
Nanoparticles deliver the goods.
    CNS & neurological disorders drug targets, 2010, Volume: 9, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Blood-Brain Barrier; Caspase 3; Cerebral Arteries; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Endothelial Cells; Humans; Hypoxia-Ischemia, Brain; Mice; Nanoparticles; Nerve Degeneration; Receptors, Transferrin; Treatment Outcome

2010
Evaluation of a new hemostatic agent in a porcine grade V liver injury model.
    The American surgeon, 2010, Volume: 76, Issue:3

    Topics: Animals; Chitosan; Disease Models, Animal; Female; Hemostasis, Surgical; Hemostatics; Swine

2010
Potential role of N-Succinyl-Chitosan in immune reconstitution after umbilical cord blood transplantation in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2011, Volume: 65, Issue:8

    Topics: Animals; Cell Proliferation; Chitosan; Cord Blood Stem Cell Transplantation; Disease Models, Animal; Hematopoiesis; Hematopoietic Cell Growth Factors; Humans; Immune System; Male; Mice; Opportunistic Infections; Spleen; T-Lymphocytes; Time Factors

2011
Effect of photocrosslinkable chitosan hydrogel and its sponges to stop bleeding in a rat liver injury model.
    Artificial organs, 2010, Volume: 34, Issue:4

    Topics: Animals; Chitosan; Disease Models, Animal; Hemorrhage; Hemostatic Techniques; Hemostatics; Hydrogels; Liver; Liver Diseases; Male; Porifera; Rats; Rats, Sprague-Dawley

2010
Comparative testing of new hemostatic agents in a swine model of extremity arterial and venous hemorrhage.
    Military medicine, 2010, Volume: 175, Issue:4

    Topics: Animals; Biopolymers; Blood Loss, Surgical; Chitosan; Disease Models, Animal; Female; Hemostatics; Male; Sus scrofa

2010
Improved myocardial performance in infarcted rat heart by co-injection of basic fibroblast growth factor with temperature-responsive chitosan hydrogel.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2010, Volume: 29, Issue:8

    Topics: Animals; Chitosan; Collagen; Disease Models, Animal; Drug Therapy, Combination; Female; Fibroblast Growth Factor 2; Heart; Hemostatics; Hydrogels; Myocardial Infarction; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Temperature; Ventricular Function, Left; Ventricular Remodeling

2010
Chitosan arrests bleeding in major hepatic injuries with clotting dysfunction: an in vivo experimental study in a model of hepatic injury in the presence of moderate systemic heparinisation.
    Annals of the Royal College of Surgeons of England, 2010, Volume: 92, Issue:7

    Topics: Animals; Bandages; Blood Coagulation Disorders; Chitosan; Disease Models, Animal; Female; Hemodynamics; Hemorrhage; Hemostatic Techniques; Hemostatics; Liver; Liver Diseases; Male; Sus scrofa; Treatment Outcome

2010
Hemostasis for severe hemorrhage with photocrosslinkable chitosan hydrogel and calcium alginate.
    Annals of biomedical engineering, 2010, Volume: 38, Issue:12

    Topics: Alginates; Animals; Biomedical Engineering; Blood Cell Count; Chitosan; Cross-Linking Reagents; Disease Models, Animal; Glucuronic Acid; Hematocrit; Hemodynamics; Hemoglobins; Hemorrhage; Hemostatic Techniques; Hemostatics; Hexuronic Acids; Humans; Hydrogels; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Ultraviolet Rays

2010
Prevention of postoperative peritoneal adhesions by O-carboxymethyl chitosan in a rat cecal abrasion model.
    Clinical and investigative medicine. Medecine clinique et experimentale, 2010, Aug-01, Volume: 33, Issue:4

    Topics: Animals; Cecum; Chitosan; Disease Models, Animal; Fibroblasts; Immunohistochemistry; Inflammation; Laparotomy; Male; Peritoneal Diseases; Postoperative Complications; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Transforming Growth Factor beta1

2010
Electrical stimulation accelerates motor functional recovery in the rat model of 15-mm sciatic nerve gap bridged by scaffolds with longitudinally oriented microchannels.
    Neurorehabilitation and neural repair, 2010, Volume: 24, Issue:8

    Topics: Action Potentials; Animals; Axons; Biocompatible Materials; Chitosan; Disease Models, Animal; Electric Stimulation; Electrophysiology; Guided Tissue Regeneration; Male; Motor Activity; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Nerve; Sciatic Neuropathy; Time Factors; Tissue Scaffolds; Treatment Outcome; Walking

2010
Local antibiotic delivery using tailorable chitosan sponges: the future of infection control?
    Journal of orthopaedic trauma, 2010, Volume: 24, Issue:9

    Topics: Amikacin; Animals; Anti-Bacterial Agents; Bacterial Infections; Biocompatible Materials; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Fractures, Open; Goats; Infection Control; Pseudomonas Infections; Staphylococcal Infections; Vancomycin

2010
Characterization and preparation of core-shell type nanoparticle for encapsulation of anticancer drug.
    Colloids and surfaces. B, Biointerfaces, 2010, Dec-01, Volume: 81, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Chitosan; Cholesterol; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Design; Drug Screening Assays, Antitumor; Female; Mice; Mice, Inbred BALB C; Molecular Conformation; Molecular Weight; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Particle Size; Polyethylene Glycols; Solubility; Surface Properties

2010
The antitumor and antimetastatic effects of N-trimethyl chitosan-encapsulated camptothecin on ovarian cancer with minimal side effects.
    Oncology reports, 2010, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Chitosan; Disease Models, Animal; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Xenograft Model Antitumor Assays

2010
Use of a modified chitosan-dextran gel to prevent peritoneal adhesions in a rat model.
    The Journal of surgical research, 2011, Volume: 171, Issue:2

    Topics: Animals; Anticoagulants; Biocompatible Materials; Cecum; Chitosan; Dextrans; Disease Models, Animal; Gels; Laparotomy; Male; Peritoneal Cavity; Peritoneum; Rats; Rats, Wistar; Tissue Adhesions; Wound Healing

2011
Local administration of chitosan microspheres after traumatic brain injury in rats: a new challenge for cyclosporine--a delivery.
    British journal of neurosurgery, 2010, Volume: 24, Issue:5

    Topics: Animals; Brain Injuries; Chitosan; Cyclosporine; Disease Models, Animal; Male; Microspheres; Mitochondria; Rats; Rats, Sprague-Dawley

2010
Intranasal immunization with chitosan/pCAGGS-flaA nanoparticles inhibits Campylobacter jejuni in a White Leghorn model.
    Journal of biomedicine & biotechnology, 2010, Volume: 2010

    Topics: Administration, Intranasal; Administration, Oral; Animals; Antibodies, Bacterial; Bacterial Vaccines; Campylobacter Infections; Campylobacter jejuni; CD4-CD8 Ratio; Chickens; Chitosan; Chlorocebus aethiops; COS Cells; Disease Models, Animal; DNA, Bacterial; Drug Stability; Flagellin; Intestinal Mucosa; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Plasmids; Vaccines, DNA; Virus Shedding

2010
Temporal and spatial modulation of chondrogenic foci in subchondral microdrill holes by chitosan-glycerol phosphate/blood implants.
    Osteoarthritis and cartilage, 2011, Volume: 19, Issue:1

    Topics: Animals; Biomarkers; Cartilage Diseases; Cell Proliferation; Chitosan; Chondrogenesis; Coagulants; Collagen; Collagen Type II; Disease Models, Animal; Glycerol; Glycosaminoglycans; Phosphates; Rabbits

2011
[Preparation and pharmacodynamic evaluation of diammonium glycyrrhizinate-loaded chitosan nanoparticles].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:16

    Topics: Animals; Chitosan; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Female; Glycyrrhizic Acid; Male; Mice; Nanoparticles

2010
Omni-Stat (Chitosan) arrests bleeding in heparinised subjects in vivo: an experimental study in a model of major peripheral vascular injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011, Volume: 39, Issue:6

    Topics: Animals; Anticoagulants; Chitosan; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Femoral Artery; Hemorrhage; Hemostatic Techniques; Hemostatics; Heparin; Male; Sus scrofa; Vascular System Injuries

2011
Chitosan oligosaccharides protect mice from LPS challenge by attenuation of inflammation and oxidative stress.
    International immunopharmacology, 2011, Volume: 11, Issue:1

    Topics: Animals; Catalase; Chitosan; Cytokines; Disease Models, Animal; Female; Glutathione; Kidney; Lipid Peroxidation; Lipopolysaccharides; Liver; Lung; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Oligosaccharides; Oxidative Stress; Sepsis; Survival Analysis

2011
Chitosan channels containing spinal cord-derived stem/progenitor cells for repair of subacute spinal cord injury in the rat.
    Neurosurgery, 2010, Volume: 67, Issue:6

    Topics: Animals; Cell Division; Cell Survival; Chitosan; Disease Models, Animal; Ectodysplasins; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hemostatics; Indoles; Locomotion; Neural Stem Cells; Psychomotor Performance; Rats; Rats, Transgenic; Rats, Wistar; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Stem Cell Transplantation

2010
The antioxidative and antilipidemic effects of different molecular weight chitosans in metabolic syndrome model rats.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:12

    Topics: Albumins; Animals; Antioxidants; Blood Glucose; Body Weight; Chitosan; Cholesterol; Cholesterol, LDL; Creatinine; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radicals; Gastrointestinal Tract; Hypolipidemic Agents; Male; Metabolic Syndrome; Molecular Weight; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Reference Values; Triglycerides

2010
[Differences of wound contraction and apoptosis in full-thickness burn wounds repaired with different artificial dermal stent in pigs].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2010, Jun-01, Volume: 48, Issue:11

    Topics: Animals; Apoptosis; Burns; Chitosan; Collagen; Disease Models, Animal; Female; Skin Transplantation; Skin, Artificial; Swine; Tissue Scaffolds

2010
[Comparative study on repair of full-thickness burn wound with different artificial dermal stent in pigs].
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2010, Volume: 26, Issue:5

    Topics: Animals; Burns; Chitosan; Collagen; Disease Models, Animal; Female; Silicones; Skin Transplantation; Skin, Artificial; Swine; Swine, Miniature; Tissue Scaffolds

2010
Hypolipidemic effects of chitosan nanoparticles in hyperlipidemia rats induced by high fat diet.
    International immunopharmacology, 2011, Volume: 11, Issue:4

    Topics: Animals; Blood Viscosity; Chitosan; Dietary Fats; Disease Models, Animal; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Nanoparticles; Particle Size; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Toxicity Tests, Acute

2011
Vaccination of mice with chitosan nanogel-associated recombinant NcPDI against challenge infection with Neospora caninum tachyzoites.
    Parasite immunology, 2011, Volume: 33, Issue:2

    Topics: Administration, Intranasal; Animals; Brain; Chitosan; Coccidiosis; Disease Models, Animal; Drug Carriers; Female; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Nanogels; Neospora; Polyethylene Glycols; Polyethyleneimine; Protein Disulfide-Isomerases; Protozoan Vaccines; Survival Analysis; Vaccination; Vaccines, Synthetic

2011
Hydrodynamic delivery of chitosan-folate-DNA nanoparticles in rats with adjuvant-induced arthritis.
    Journal of biomedicine & biotechnology, 2011, Volume: 2011

    Topics: Analysis of Variance; Animals; Arthritis, Experimental; beta-Galactosidase; Chitosan; Dinoprostone; Disease Models, Animal; DNA; Drug Delivery Systems; Female; Folic Acid; Freund's Adjuvant; Histocytochemistry; Humans; Injections, Intravenous; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Muscle, Skeletal; Nanoconjugates; Nanoparticles; Rats; Rats, Inbred Lew; Tarsus, Animal; Tissue Distribution

2011
Use of chitosan scaffolds for repairing rat sciatic nerve defects.
    Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 2010, Volume: 115, Issue:3

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Male; Nerve Regeneration; Neurosurgical Procedures; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Tissue Scaffolds

2010
Evaluation of chitosan gel containing liposome-loaded epidermal growth factor on burn wound healing.
    International wound journal, 2011, Volume: 8, Issue:4

    Topics: Administration, Topical; Animals; Biocompatible Materials; Biopsy; Burns; Chitosan; Disease Models, Animal; Epidermal Growth Factor; Epidermis; Female; Follow-Up Studies; Gels; Humans; Liposomes; Rats; Rats, Sprague-Dawley; Skin; Treatment Outcome; Wound Healing

2011
Therapeutic effect of carboxymethylated and quanternized chitosan on insulin resistance in high-fat-diet-induced rats and 3T3-L1 adipocytes.
    Journal of biomaterials science. Polymer edition, 2012, Volume: 23, Issue:10

    Topics: 3T3 Cells; Adipocytes; Adiponectin; Animals; Anti-Obesity Agents; Chitosan; Diet, High-Fat; Disease Models, Animal; Insulin Resistance; Leptin; Male; Mice; Obesity; PPAR gamma; Random Allocation; Rats, Wistar; Resistin; RNA, Messenger

2012
Antitumor activity and antioxidant role of a novel water-soluble carboxymethyl chitosan-based copolymer.
    Drug development and industrial pharmacy, 2011, Volume: 37, Issue:12

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Proliferation; Chitosan; Disease Models, Animal; Female; Flow Cytometry; Mice; Polymers; Random Allocation; Spectroscopy, Fourier Transform Infrared

2011
Animal model of implant capsular contracture: effects of chitosan.
    Aesthetic surgery journal, 2011, Volume: 31, Issue:5

    Topics: Animals; Breast Implants; Chitosan; Disease Models, Animal; Female; Implant Capsular Contracture; Interleukin-8; Microdialysis; Oligosaccharides; Rabbits; Silicone Gels; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2011
N-Succinyl-chitosan systems for 5-aminosalicylic acid colon delivery: in vivo study with TNBS-induced colitis model in rats.
    International journal of pharmaceutics, 2011, Sep-15, Volume: 416, Issue:1

    Topics: Absorption; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Colitis; Colon; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Freeze Drying; Intestinal Mucosa; Lymphocyte Activation; Male; Mesalamine; Organ Size; Peroxidase; Polymers; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid

2011
Biochemical and pathological evidences on the benefit of a new biodegradable nanoparticles of probiotic extract in murine colitis.
    Fundamental & clinical pharmacology, 2012, Volume: 26, Issue:5

    Topics: Animals; Chitosan; Colitis; Cytokines; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Freeze Drying; Inflammation Mediators; Lactic Acid; Lipid Peroxidation; Male; Nanoparticles; Pilot Projects; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Probiotics; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid

2012
Chitosan/TPP-hyaluronic acid nanoparticles: a new vehicle for gene delivery to the spinal cord.
    Journal of biomaterials science. Polymer edition, 2012, Volume: 23, Issue:11

    Topics: Animals; Cell Survival; Cells, Cultured; Chitosan; Disease Models, Animal; DNA; Gene Transfer Techniques; Heterocyclic Compounds; Hyaluronic Acid; Male; Mice; Nanoparticles; Neural Stem Cells; Organophosphorus Compounds; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tissue Culture Techniques

2012
Enhanced healing of rat calvarial defects with sulfated chitosan-coated calcium-deficient hydroxyapatite/bone morphogenetic protein 2 scaffolds.
    Tissue engineering. Part A, 2012, Volume: 18, Issue:1-2

    Topics: Animals; Biomechanical Phenomena; Bone Morphogenetic Protein 2; Bone Regeneration; Calcification, Physiologic; Chitosan; Coated Materials, Biocompatible; Delayed-Action Preparations; Disease Models, Animal; Durapatite; Fluorescent Dyes; Kinetics; Male; Microscopy, Electron, Scanning; Osteogenesis; Rats; Rats, Inbred F344; Skull; Tissue Scaffolds; Wound Healing; X-Ray Microtomography

2012
Hemostatic effect of a chitosan linear polymer (Celox®) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2011, Volume: 17, Issue:3

    Topics: Animals; Anticoagulants; Chitosan; Disease Models, Animal; Female; Femoral Artery; Hemorrhage; Hemostatics; Hypothermia, Induced; Rats; Rats, Sprague-Dawley; Warfarin

2011
Enhanced immune response and protective efficacy of a Treponema pallidum Tp92 DNA vaccine vectored by chitosan nanoparticles and adjuvanted with IL-2.
    Human vaccines, 2011, Volume: 7, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Bacterial; Bacterial Vaccines; Chitosan; Disease Models, Animal; Drug Carriers; Injections, Intramuscular; Interleukin-2; Lymphocytes; Male; Nanoparticles; Plasmids; Rabbits; Skin Tests; Syphilis; Treponema pallidum; Vaccines, DNA

2011
Biodegradable ocular inserts for sustained delivery of brimonidine tartarate: preparation and in vitro/in vivo evaluation.
    AAPS PharmSciTech, 2011, Volume: 12, Issue:4

    Topics: Absorbable Implants; Acrylic Resins; Administration, Ophthalmic; Adrenergic alpha-2 Receptor Agonists; Alginates; Animals; Brimonidine Tartrate; Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Compounding; Glaucoma; Glucuronic Acid; Hexuronic Acids; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Intraocular Pressure; Kinetics; Methylcellulose; Ophthalmic Solutions; Polymers; Polymethacrylic Acids; Polyvinyls; Povidone; Quinoxalines; Rabbits; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; X-Ray Diffraction

2011
Gene therapy of endometriosis introduced by polymeric micelles with glycolipid-like structure.
    Biomaterials, 2012, Volume: 33, Issue:2

    Topics: Animals; Apoptosis; Chitosan; Disease Models, Animal; DNA; Endometriosis; Eye Proteins; Feasibility Studies; Female; Gene Transfer Techniques; Genetic Therapy; Glycolipids; Micelles; Microscopy, Electron, Transmission; Nerve Growth Factors; Particle Size; Plasmids; Polymers; Rats; Rats, Sprague-Dawley; Serpins

2012
Intracorporeal use of advanced local hemostatics in a damage control swine model of grade IV liver injury.
    The Journal of trauma, 2011, Volume: 71, Issue:5

    Topics: Analysis of Variance; Animals; Bandages; Biopolymers; Chitosan; Disease Models, Animal; Female; Hemorrhage; Hemostatics; Liver; Random Allocation; Statistics, Nonparametric; Swine; Zeolites

2011
Reduction of post-traumatic neuroma and epineural scar formation in rat sciatic nerve by application of microcrystallic chitosan.
    Microsurgery, 2011, Volume: 31, Issue:8

    Topics: Administration, Topical; Animals; Chitosan; Cicatrix; Disease Models, Animal; Hydrogels; Male; Neuroma; Neurosurgical Procedures; Peripheral Nerve Injuries; Random Allocation; Rats; Rats, Wistar; Reference Values; Risk Assessment; Sciatica; Sensitivity and Specificity; Wound Healing

2011
Coated chitosan pellets containing rutin intended for the treatment of inflammatory bowel disease: in vitro characteristics and in vivo evaluation.
    International journal of pharmaceutics, 2012, Jan-17, Volume: 422, Issue:1-2

    Topics: Administration, Oral; Alginates; Animals; Anti-Inflammatory Agents; Buffers; Caffeic Acids; Chemistry, Pharmaceutical; Chitosan; Colitis; Colon; Disease Models, Animal; Drug Compounding; Drug Implants; Drug Stability; Gastrointestinal Agents; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Hypromellose Derivatives; Male; Methylcellulose; Rats; Rats, Wistar; Rutin; Solubility; Technology, Pharmaceutical; Time Factors; Trinitrobenzenesulfonic Acid; Zinc Acetate

2012
Erythropoietin-loaded oligochitosan nanoparticles for treatment of periventricular leukomalacia.
    International journal of pharmaceutics, 2012, Jan-17, Volume: 422, Issue:1-2

    Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Chemistry, Pharmaceutical; Chitin; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Erythropoietin; GAP-43 Protein; Humans; Infant, Newborn; Injections, Intraperitoneal; Leukomalacia, Periventricular; Liver; Magnetic Resonance Imaging; Nanotechnology; Oligosaccharides; Particle Size; Rats; Solubility; Technology, Pharmaceutical

2012
Fluorescent labeling of chitosan for use in non-invasive monitoring of degradation in tissue engineering.
    Journal of tissue engineering and regenerative medicine, 2013, Volume: 7, Issue:1

    Topics: Animals; Biocompatible Materials; Body Weight; Cell Line; Chitosan; Disease Models, Animal; Fluorescent Dyes; Humans; Mice; Microscopy, Confocal; Polymers; Regression Analysis; Rhodamines; Solvents; Spectroscopy, Fourier Transform Infrared; Time Factors; Tissue Engineering

2013
Inhibitory effect of chitosan-containing lotion on scratching response of hairless mice with atopic dermatitis-like dry skin.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:12

    Topics: Animals; Behavior, Animal; Chitosan; Dermatitis, Atopic; Diet; Disease Models, Animal; Emollients; Ethanol; Female; Mice; Mice, Hairless; Pruritus; Skin Temperature; Water

2011
A peptide-modified chitosan-collagen hydrogel for cardiac cell culture and delivery.
    Acta biomaterialia, 2012, Volume: 8, Issue:3

    Topics: Angiopoietin-1; Animals; Chitosan; Collagen Type I; Disease Models, Animal; Humans; Hydrogels; Male; Mice; Myocardial Infarction; Myocytes, Cardiac; Peptides; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley

2012
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
    Cell biochemistry and biophysics, 2012, Volume: 62, Issue:1

    Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; Knee Joint; Male; Mitomycin; Rabbits; Tissue Adhesions

2012
Bio-inspired tissue adhesive chitosan/pluronic composite hydrogel.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Adhesiveness; Animals; Caffeic Acids; Catechols; Chitosan; Cross-Linking Reagents; Disease Models, Animal; Drug Carriers; Hemorrhage; Hemostatic Techniques; Hydrogels; Mice; Poloxamer; Rats; Sulfhydryl Compounds; Temperature; Tissue Adhesives; Tissue Scaffolds

2011
Use of a modified chitosan-dextran gel to prevent peritoneal adhesions in a porcine hemicolectomy model.
    The Journal of surgical research, 2012, Volume: 176, Issue:2

    Topics: Anastomosis, Surgical; Animals; Biocompatible Materials; Cecum; Chitosan; Colectomy; Dextrans; Disease Models, Animal; Female; Hydrogels; Ileum; Laparotomy; Peritoneum; Surgical Wound Infection; Sus scrofa; Tissue Adhesions; Treatment Outcome

2012
Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE-antigen complex-stimulated RBL-2H3 cells and asthma model mice.
    International immunopharmacology, 2012, Volume: 12, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Chitosan; Disease Models, Animal; Female; Glucosamine; Hypersensitivity; Immunoglobulin E; Interleukins; Leukemia, Basophilic, Acute; Lung; Mice; Mice, Inbred BALB C; Molecular Weight; Oligosaccharides; Ovalbumin; Tumor Necrosis Factor-alpha

2012
Targeting of primary breast cancers and metastases in a transgenic mouse model using rationally designed multifunctional SPIONs.
    ACS nano, 2012, Mar-27, Volume: 6, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Breast Neoplasms; Cell Line, Tumor; Chemical Phenomena; Chitosan; Disease Models, Animal; Drug Design; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Transgenic; Neoplasm Metastasis; Polyethylene Glycols; Receptor, ErbB-2; Substrate Specificity

2012
The effects of chitosan and low dose dexamethasone on extrahepatic cholestasis after bile duct ligation in Wistar rats.
    Acta physiologica Hungarica, 2012, Volume: 99, Issue:1

    Topics: Animals; Anticholesteremic Agents; Antioxidants; Chitosan; Cholestasis, Extrahepatic; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucocorticoids; Glutathione; Ligation; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar

2012
Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action.
    Pharmacological research, 2012, Volume: 66, Issue:1

    Topics: Acetic Acid; Acute Disease; Administration, Oral; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Chitosan; Chronic Disease; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Gastrointestinal Agents; Humans; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-6; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; Permeability; Reactive Oxygen Species; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha

2012
A new injectable radiopaque chitosan-based sclerosing embolizing hydrogel for endovascular therapies.
    Acta biomaterialia, 2012, Volume: 8, Issue:7

    Topics: Animals; Chitosan; Contrast Media; Disease Models, Animal; Dogs; Elastic Modulus; Embolization, Therapeutic; Endovascular Procedures; Factor VIII; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogen-Ion Concentration; Iliac Aneurysm; In Vitro Techniques; Injections; Microscopy, Electron, Scanning; Rheology; Sclerosing Solutions; Sodium Tetradecyl Sulfate; Time Factors

2012
Determination of efficacy of novel modified chitosan sponge dressing in a lethal arterial injury model in swine.
    The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:4

    Topics: Adhesiveness; Animals; Arteries; Bandages; Chitosan; Disease Models, Animal; Female; Femoral Artery; Hemorrhage; Hemostatic Techniques; Surgical Sponges; Swine

2012
A chitosan-based sinus sealant for reduction of adhesion formation in rabbit and sheep models.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2012, Volume: 147, Issue:2

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Paranasal Sinuses; Rabbits; Sheep; Sinusitis; Tissue Adhesions; Tissue Adhesives

2012
Genipin-cross-linked microencapsulated human adipose stem cells augment transplant retention resulting in attenuation of chronically infarcted rat heart fibrosis and cardiac dysfunction.
    Cell transplantation, 2012, Volume: 21, Issue:12

    Topics: Adipocytes; Alginates; Animals; Cell Differentiation; Cells, Cultured; Chitosan; Coronary Vessels; Disease Models, Animal; Female; Glucuronic Acid; Hexuronic Acids; Humans; Iridoids; Male; Myocardial Infarction; Myocardium; Neovascularization, Pathologic; Rats; Rats, Inbred Lew; Regenerative Medicine; Stem Cell Transplantation; Stem Cells; Vascular Endothelial Growth Factor A

2012
Effect of fulminant hepatic failure porcine plasma supplemented with essential components on encapsulated rat hepatocyte spheroids.
    Transplantation proceedings, 2012, Volume: 44, Issue:4

    Topics: Albumins; Alginates; Animals; Bioreactors; Cell Survival; Cells, Immobilized; Chitosan; Culture Media; Disease Models, Animal; Glucuronic Acid; Hepatocytes; Hexuronic Acids; Humans; Liver Failure, Acute; Liver, Artificial; Male; Plasma; Rats; Rats, Sprague-Dawley; Spheroids, Cellular; Swine; Time Factors; Urea

2012
[Study on bone marrow mesenchymal stem cells derived osteoblasts and endothelial cells compound with chitosan/hydroxyapatite scaffold to construct vascularized tissue engineered bone].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2012, Volume: 26, Issue:4

    Topics: Animals; Biocompatible Materials; Bone Marrow Cells; Cells, Cultured; Chitosan; Coculture Techniques; Disease Models, Animal; Durapatite; Endothelial Cells; Male; Mesenchymal Stem Cells; Neovascularization, Physiologic; Osteoblasts; Osteogenesis; Radius; Rats; Rats, Sprague-Dawley; Tissue Engineering; Tissue Scaffolds

2012
Assessment of an asymmetrical coating stent with sirolimus released from ablumial matrix in porcine model.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2012, Volume: 101, Issue:11

    Topics: Acetylcholine; Animals; Cardiovascular Agents; Chitosan; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug-Eluting Stents; Endothelial Cells; Heparin; Hyperplasia; Metals; Microscopy, Electron, Scanning; Neointima; Percutaneous Coronary Intervention; Prosthesis Design; Sirolimus; Swine; Swine, Miniature; Time Factors; Ultrasonography, Interventional; Vasoconstriction

2012
Synthesis, characterization of chitosan-tripolyphosphate conjugated chloroquine nanoparticle and its in vivo anti-malarial efficacy against rodent parasite: a dose and duration dependent approach.
    International journal of pharmaceutics, 2012, Sep-15, Volume: 434, Issue:1-2

    Topics: Animals; Antimalarials; Chitosan; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Malaria; Male; Mice; Nanoparticles; Plasmodium berghei; Polyphosphates; Time Factors

2012
Electrical stimulation to conductive scaffold promotes axonal regeneration and remyelination in a rat model of large nerve defect.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Action Potentials; Animals; Axons; Brain-Derived Neurotrophic Factor; Carrier Proteins; Chitosan; Disease Models, Animal; Electric Stimulation; Electrophysiology; Male; Myelin P0 Protein; Myelin Sheath; Nerve Regeneration; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; S100 Proteins; Sciatic Nerve; Up-Regulation

2012
Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: pharmacological and toxicological tests.
    Burns : journal of the International Society for Burn Injuries, 2013, Volume: 39, Issue:1

    Topics: Analysis of Variance; Animals; Biocompatible Materials; Burns; Chitosan; Disease Models, Animal; Hydrogels; Male; Polyvinyl Alcohol; Rats; Rats, Wistar; Skin; Wound Healing

2013
[Injectable borate glass/chitosan composite as drug carrier for treatment of chronic osteomyelitis].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2012, Volume: 26, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Borates; Calcium Sulfate; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Female; Glass; Injections; Male; Materials Testing; Osteomyelitis; Rabbits; Staphylococcal Infections; Vancomycin; X-Ray Diffraction

2012
Peritoneal macrophages mediated delivery of chitosan/siRNA nanoparticle to the lesion site in a murine radiation-induced fibrosis model.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:8

    Topics: Animals; Chitosan; Disease Models, Animal; Immunoenzyme Techniques; Inflammation; Injections, Intraperitoneal; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Microscopy, Fluorescence; Nanoparticles; Radiation Pneumonitis; RNA, Small Interfering; Skin Diseases; Tumor Necrosis Factor-alpha

2013
Effects of chitosan on healing and strength of colonic anastomosis in rats.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:10

    Topics: Anastomosis, Surgical; Animals; Chitosan; Collagen; Colon; Disease Models, Animal; Female; Hemostatics; Rats; Rats, Wistar; Tensile Strength; Time Factors; Tissue Adhesions; Treatment Outcome; Wound Healing

2012
Risk of cardiovascular disease is suppressed by dietary supplementation with protamine and chitooligosaccharide in Sprague-Dawley rats.
    Molecular medicine reports, 2013, Volume: 7, Issue:1

    Topics: Animals; Cardiovascular Diseases; Chitosan; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Lipid Metabolism; Lipids; Liver; Male; Oligosaccharides; Protamines; Rats; Rats, Sprague-Dawley; Risk Factors

2013
Development of O/W nanoemulsions for ophthalmic administration of timolol.
    International journal of pharmaceutics, 2013, Jan-20, Volume: 440, Issue:2

    Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Animals; Biological Availability; Chitosan; Corneal Opacity; Disease Models, Animal; Drug Delivery Systems; Drug Stability; Emulsions; In Vitro Techniques; Nanotechnology; Rabbits; Sodium Hydroxide; Succinates; Timolol

2013
Enhanced hemostatic performance of tranexamic acid-loaded chitosan/alginate composite microparticles.
    Journal of biomedicine & biotechnology, 2012, Volume: 2012

    Topics: Absorption; Alginates; Animals; Cell Death; Cell Shape; Chitosan; Disease Models, Animal; Female; Fibroblasts; Glucuronic Acid; Hemorrhage; Hemostatics; Hexuronic Acids; Male; Mice; Microscopy, Electron, Scanning; Microspheres; Particle Size; Powders; Rabbits; Spectrophotometry, Infrared; Tranexamic Acid; Water

2012
Preparation of amphiphilic hollow carbon nanosphere loaded insulin for oral delivery.
    Colloids and surfaces. B, Biointerfaces, 2013, Mar-01, Volume: 103

    Topics: Administration, Oral; Animals; Buffers; Carbon; Chitosan; Circular Dichroism; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Hydrogen-Ion Concentration; Hypoglycemia; Insulin; Kinetics; Male; Nanospheres; Particle Size; Polymethacrylic Acids; Rats; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Zebrafish

2013
A new strategy based on SmRho protein loaded chitosan nanoparticles as a candidate oral vaccine against schistosomiasis.
    PLoS neglected tropical diseases, 2012, Volume: 6, Issue:11

    Topics: Adjuvants, Immunologic; Administration, Oral; Alginates; Animals; Antigens, Helminth; Body Fluids; Chitosan; Disease Models, Animal; Drug Carriers; Drug Stability; Female; Glucuronic Acid; Granuloma; Hexuronic Acids; Mice; Mice, Inbred C57BL; Nanoparticles; Oligodeoxyribonucleotides; Schistosomiasis; Vaccines

2012
Mucoadhesive chitosan-coated cationic microemulsion of dexamethasone for ocular delivery: in vitro and in vivo evaluation.
    Current eye research, 2013, Volume: 38, Issue:3

    Topics: Animals; Aqueous Humor; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Dexamethasone; Disease Models, Animal; Drug Delivery Systems; Drug Stability; Emulsions; Glucocorticoids; Microscopy, Electron, Transmission; Mucin-2; Particle Size; Polyamines; Polyelectrolytes; Polysorbates; Propylene Glycol; Rabbits; Solubility; Uveitis; Viscosity

2013
Cardiac repair using chitosan-hyaluronan/silk fibroin patches in a rat heart model with myocardial infarction.
    Carbohydrate polymers, 2013, Jan-30, Volume: 92, Issue:1

    Topics: Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Fibroins; Hyaluronic Acid; Male; Myocardial Infarction; Rats; Silk; Wound Healing

2013
Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: pharmacodynamic, pharmacokinetic and scintigraphy study in mice model.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Feb-14, Volume: 48, Issue:3

    Topics: Administration, Intranasal; Animals; Antiparkinson Agents; Behavior, Animal; Blood-Brain Barrier; Brain; Bromocriptine; Catalepsy; Chitosan; Disease Models, Animal; Drug Compounding; Drug Delivery Systems; Hypokinesia; Injections, Intravenous; Male; Mice; Nanoparticles; Neurons; Parkinson Disease; Radionuclide Imaging; Random Allocation; Sodium Pertechnetate Tc 99m; Tissue Distribution

2013
Efficacy, safety, and biodegradation of a degradable scleral buckle of chitosan-gelatin polymer in rabbits.
    Retina (Philadelphia, Pa.), 2013, Volume: 33, Issue:5

    Topics: Animals; Biotransformation; Chitosan; Disease Models, Animal; Electroretinography; Gelatin; Polymers; Rabbits; Retinal Detachment; Scleral Buckling; Ultrasonography

2013
Assessment of the immune responses to Treponema pallidum Gpd DNA vaccine adjuvanted with IL-2 and chitosan nanoparticles before and after Treponema pallidum challenge in rabbits.
    Science China. Life sciences, 2013, Volume: 56, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Proteins; Bacterial Vaccines; Chitosan; Disease Models, Animal; Genes, Bacterial; HeLa Cells; Humans; Interferon-gamma; Interleukin-2; Nanoparticles; Rabbits; Syphilis; T-Lymphocytes; Treponema pallidum; Vaccines, DNA

2013
Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: an ex vivo and in vivo study using an NC/Nga mouse model.
    International journal of pharmaceutics, 2013, Feb-28, Volume: 444, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Chitosan; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Models, Animal; Drug Carriers; Hydrocortisone; Mice; Nanoparticles; Phenylethyl Alcohol; Skin; Skin Absorption

2013
Long-term preclinical evaluation of the intracorporeal use of advanced local hemostatics in a damage-control swine model of grade IV liver injury.
    The journal of trauma and acute care surgery, 2013, Volume: 74, Issue:2

    Topics: Animals; Chitosan; Disease Models, Animal; Female; Hemorrhage; Hemostatics; Intestine, Small; Kaolin; Kidney; Liver; Myocardium; Swine

2013
Aceclofenac-loaded chitosan-tamarind seed polysaccharide interpenetrating polymeric network microparticles.
    Colloids and surfaces. B, Biointerfaces, 2013, May-01, Volume: 105

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Carrageenan; Chitosan; Diclofenac; Disease Models, Animal; Drug Delivery Systems; Edema; Glutaral; In Vitro Techniques; Male; Microspheres; Polymers; Polysaccharides; Rats; Rats, Sprague-Dawley; Seeds; Spectroscopy, Fourier Transform Infrared; Tamarindus

2013
An investigation on skin wound healing in mice with a taurine-chitosan gel formulation.
    Amino acids, 2002, Volume: 22, Issue:2

    Topics: Animals; Antioxidants; Biocompatible Materials; Chemistry, Pharmaceutical; Chitin; Chitosan; Collagen; Disease Models, Animal; Drug Delivery Systems; Hydroxyproline; Materials Testing; Mice; Microscopy, Electron; Skin Diseases; Taurine; Tensile Strength; Wound Healing

2002
Effect of a chitosan-based hemostatic dressing on blood loss and survival in a model of severe venous hemorrhage and hepatic injury in swine.
    The Journal of trauma, 2003, Volume: 54, Issue:1

    Topics: Animals; Bandages; Blood Volume; Chitin; Chitosan; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fluid Therapy; Hemorrhage; Hemostatic Techniques; Hemostatics; Liver; Male; Random Allocation; Resuscitation; Survival Analysis; Swine; Time Factors

2003
Antioxidative effect of chitosan on chronic carbon tetrachloride induced hepatic injury in rats.
    Toxicology, 2003, May-01, Volume: 187, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Body Weight; Carbon Tetrachloride Poisoning; Catalase; Chitin; Chitosan; Cytochrome P-450 CYP2E1; Disease Models, Animal; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Organ Size; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances

2003
Eight-week histological analysis on the effect of chitosan on surgically created one-wall intrabony defects in beagle dogs.
    Journal of clinical periodontology, 2003, Volume: 30, Issue:5

    Topics: Alveolar Bone Loss; Alveolar Process; Animals; Biopolymers; Bone Regeneration; Bone Substitutes; Chitin; Chitosan; Collagen; Connective Tissue; Dental Cementum; Disease Models, Animal; Dogs; Epithelial Attachment; Male; Mandible; Maxilla; Regeneration; Statistics, Nonparametric; Surgical Flaps

2003
Comparative study of protective effects of chitin, chitosan, and N-acetyl chitohexaose against Pseudomonas aeruginosa and Listeria monocytogenes infections in mice.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Ascitic Fluid; Chitin; Chitosan; Disease Models, Animal; Exudates and Transudates; Injections, Intraperitoneal; Listeria monocytogenes; Listeriosis; Mice; Mice, Inbred Strains; Oligosaccharides; Peroxidase; Pseudomonas aeruginosa; Pseudomonas Infections

2003
Use of methylene blue and N,O-carboxymethylchitosan to prevent postoperative adhesions in a rat uterine horn model.
    Fertility and sterility, 2003, Volume: 80 Suppl 2

    Topics: Adjuvants, Pharmaceutic; Animals; Chitin; Chitosan; Disease Models, Animal; Female; Methylene Blue; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Tissue Adhesions; Uterus

2003
[Experimental studies on adriamycin alginate-chitosan microcapsules in the treatment of rabbit VX2 carcinoma in the extremity].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2003, Volume: 41, Issue:12

    Topics: Alginates; Animals; Capsules; Chemoembolization, Therapeutic; Chitin; Chitosan; Disease Models, Animal; Doxorubicin; Glucuronic Acid; Hexuronic Acids; In Situ Nick-End Labeling; Neoplasms, Experimental; Proliferating Cell Nuclear Antigen; Rabbits

2003
Effects of diazeniumdiolates (NONOates) and methylene blue on the reduction of postoperative adhesion in rats.
    Gynecologic and obstetric investigation, 2004, Volume: 57, Issue:4

    Topics: Animals; Chitin; Chitosan; Disease Models, Animal; Female; Methylene Blue; Peritoneal Diseases; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Severity of Illness Index; Tissue Adhesions; Uterus

2004
Modulation of immune response to group C meningococcal conjugate vaccine given intranasally to mice together with the LTK63 mucosal adjuvant and the trimethyl chitosan delivery system.
    The Journal of infectious diseases, 2004, Mar-01, Volume: 189, Issue:5

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Chitin; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Meningitis, Meningococcal; Meningococcal Vaccines; Mice; Mice, Inbred BALB C; Neisseria meningitidis, Serogroup C

2004
Application of a zeolite hemostatic agent achieves 100% survival in a lethal model of complex groin injury in Swine.
    The Journal of trauma, 2004, Volume: 56, Issue:5

    Topics: Adsorption; Animals; Bandages; Cardiac Output; Chitin; Chitosan; Disease Models, Animal; Drug Evaluation, Preclinical; Femoral Artery; Femoral Vein; Groin; Hemorrhage; Hemostatics; Monitoring, Physiologic; Random Allocation; Resuscitation; Survival Rate; Swine; Thigh; Time Factors; Warfare; Wounds, Penetrating; Zeolites

2004
Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:8

    Topics: Animals; Arthritis; Biocompatible Materials; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Inflammation; Injections, Intra-Articular; Joints; Materials Testing; Microspheres; Paclitaxel; Rabbits; Synovial Fluid; Treatment Outcome

2004
The effects of carboxymethylated chitosan on metalloproteinase-1, -3 and tissue inhibitor of metalloproteinase-1 gene expression in cartilage of experimental osteoarthritis.
    Rheumatology international, 2005, Volume: 26, Issue:1

    Topics: Acids; Animals; Antirheumatic Agents; Cartilage, Articular; Chitosan; Disease Models, Animal; Gene Expression; Injections, Intra-Articular; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Methylation; Molecular Weight; Osteoarthritis; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2005
Efficacy of photocrosslinkable chitosan hydrogel containing fibroblast growth factor-2 in a rabbit model of chronic myocardial infarction.
    The Journal of surgical research, 2005, Jun-01, Volume: 126, Issue:1

    Topics: Animals; Chitosan; Coronary Circulation; Disease Models, Animal; Fibroblast Growth Factor 2; Hydrogels; Male; Myocardial Infarction; Myocardium; Rabbits

2005
Hemostatic efficacy of two advanced dressings in an aortic hemorrhage model in Swine.
    The Journal of trauma, 2005, Volume: 59, Issue:1

    Topics: Analysis of Variance; Animals; Aorta, Abdominal; Chitosan; Disease Models, Animal; Female; Fibrin Tissue Adhesive; Hemorrhage; Hemostatic Techniques; Occlusive Dressings; Random Allocation; Statistics, Nonparametric; Swine; Treatment Outcome

2005
The efficiency of dexamethasone sodium phosphate-encapsulated chitosan microspheres after cold injury.
    Surgical neurology, 2005, Volume: 64 Suppl 2

    Topics: Animals; Brain Edema; Brain Injuries; Chitosan; Cold Temperature; Dexamethasone; Disease Models, Animal; Drug Delivery Systems; Female; Lipid Peroxidation; Male; Microspheres; Rats; Rats, Sprague-Dawley

2005
The preparation of ciprofloxacin hydrochloride-loaded chitosan and pectin microspheres: their evaluation in an animal osteomyelitis model.
    The Journal of bone and joint surgery. British volume, 2006, Volume: 88, Issue:2

    Topics: Animals; Anti-Infective Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Chitosan; Ciprofloxacin; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Drug Evaluation, Preclinical; Male; Microscopy, Electron, Scanning; Microspheres; Osteomyelitis; Pectins; Rats; Rats, Wistar; Staphylococcal Infections; Treatment Outcome

2006
[Repair of peripheral nerve gap with the use of tissue engineering scaffold complex].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2005, Volume: 27, Issue:6

    Topics: Absorbable Implants; Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Feasibility Studies; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; Nerve Growth Factors; Nerve Regeneration; Peripheral Nerve Injuries; Peripheral Nerves; Prosthesis Implantation; Rats; Rats, Sprague-Dawley; Sepharose; Stents; Tissue Engineering

2005
An intranasal vaccine targeting both the Bacillus anthracis toxin and bacterium provides protection against aerosol spore challenge in rabbits.
    Vaccine, 2006, May-01, Volume: 24, Issue:18

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Aerosols; Animals; Anorexia; Anthrax; Anthrax Vaccines; Antibodies, Bacterial; Antigens, Bacterial; Bacillus anthracis; Bacterial Capsules; Bacterial Toxins; Chitosan; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunoglobulin G; Inhalation Exposure; Lipid A; Neutralization Tests; Polyglutamic Acid; Rabbits; Recombinant Fusion Proteins

2006
Characterization of biodegradable chitosan microspheres containing vancomycin and treatment of experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus with prepared microspheres.
    International journal of pharmaceutics, 2006, Jul-24, Volume: 317, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Biodegradation, Environmental; Chitosan; Colony Count, Microbial; Disease Models, Animal; Drug Compounding; Drug Implants; Injections, Intramuscular; Male; Methicillin Resistance; Microspheres; Osteomyelitis; Particle Size; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Vancomycin

2006
N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model.
    Vaccine, 2007, Jan-02, Volume: 25, Issue:1

    Topics: Administration, Intranasal; Animals; Antibodies, Viral; Antigens, Viral; Chitosan; Disease Models, Animal; Drug Delivery Systems; Female; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Immunoglobulin A, Secretory; Immunoglobulin G; Influenza A Virus, H3N2 Subtype; Influenza Vaccines; Mice; Mice, Inbred C57BL; Nanoparticles; Vaccination

2007
Testing of modified zeolite hemostatic dressings in a large animal model of lethal groin injury.
    The Journal of trauma, 2006, Volume: 61, Issue:6

    Topics: Animals; Bandages; Barium; Chitosan; Disease Models, Animal; Groin; Hemostatics; Ion Exchange; Shock, Hemorrhagic; Silver; Sodium; Swine; Wounds, Penetrating; Zeolites

2006
Loss of cell wall alpha(1-3) glucan affects Cryptococcus neoformans from ultrastructure to virulence.
    Molecular microbiology, 2007, Volume: 63, Issue:5

    Topics: Animals; beta-Glucans; Caenorhabditis elegans; Cell Wall; Chitin; Chitosan; Cryptococcus neoformans; Disease Models, Animal; Gene Deletion; Glucans; Glucosyltransferases; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mutagenesis, Insertional; Virulence

2007
Evaluation of semi-interpenetrating polymer networks composed of chitosan and poloxamer for wound dressing application.
    International journal of pharmaceutics, 2007, Aug-16, Volume: 341, Issue:1-2

    Topics: Adsorption; Animals; Bandages; Biocompatible Materials; Burns; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Dehydroepiandrosterone; Disease Models, Animal; Drug Carriers; Drug Compounding; Female; Fibroblasts; Humans; Hydrolysis; Keratinocytes; Mice; Mice, Inbred BALB C; NIH 3T3 Cells; Poloxamer; Skin; Volatilization; Water; Wound Healing

2007
Physical properties and biocompatibility of a porous chitosan-based fiber-reinforced conduit for nerve regeneration.
    Biotechnology letters, 2007, Volume: 29, Issue:11

    Topics: Animals; Biocompatible Materials; Cells, Cultured; Chitosan; Disease Models, Animal; Female; Guided Tissue Regeneration; Nerve Regeneration; Neurons; Rats; Rats, Wistar; Tissue Scaffolds

2007
Phenotypic and functional characterisation of ovine mesenchymal stem cells: application to a cartilage defect model.
    Annals of the rheumatic diseases, 2008, Volume: 67, Issue:3

    Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Chitosan; Disease Models, Animal; Female; Hematopoiesis; Immune Tolerance; Immunophenotyping; Knee Injuries; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Patella; Sheep, Domestic; Tissue Engineering; Treatment Outcome; Wound Healing

2008
Histological evaluation of novel ossicular chain replacement prostheses: an animal study in rabbits.
    Acta oto-laryngologica, 2007, Volume: 127, Issue:8

    Topics: Animals; Biocompatible Materials; Ceramics; Chitosan; Coated Materials, Biocompatible; Dental Porcelain; Disease Models, Animal; Durapatite; Ear Diseases; Ear, Middle; Female; Follow-Up Studies; Granulation Tissue; Mucous Membrane; Ossicular Prosthesis; Ossicular Replacement; Prosthesis Design; Rabbits; Treatment Outcome

2007
[Preparation and evaluation of chitosan/alginate microsphere as a novel biodegradable haemostatic powder].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2007, Volume: 21, Issue:8

    Topics: Alginates; Animals; Biocompatible Materials; Chitosan; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hemorrhage; Hemostatics; Male; Microspheres; Particle Size; Powders; Rabbits; Spleen; Technology, Pharmaceutical

2007
Effect of high molecular weight water-soluble chitosan on the trabecular bone and thickness in ovariectomized rats.
    Immunopharmacology and immunotoxicology, 2007, Volume: 29, Issue:3-4

    Topics: Alkaline Phosphatase; Animals; Biomechanical Phenomena; Bone and Bones; Calcium; Calcium, Dietary; Chitosan; Disease Models, Animal; Female; Femur Neck; Humans; Molecular Weight; Osteoblasts; Osteoclasts; Ovariectomy; Phosphorus; Rats; Rats, Sprague-Dawley; Solubility; Thyroxine; Trabecular Meshwork; Water

2007
siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma.
    Nucleic acids research, 2008, Volume: 36, Issue:1

    Topics: Adsorption; Animals; Bucrylate; Carcinoma, Papillary; Cell Line, Transformed; Chitosan; Disease Models, Animal; Humans; Mice; Mice, Nude; Nanoparticles; NIH 3T3 Cells; Oncogene Proteins, Fusion; Plasmids; Polymers; Protein-Tyrosine Kinases; RNA Interference; RNA, Small Interfering; Sequence Analysis, RNA; Thyroid Neoplasms

2008
Monoolein and chitosan gels as potential carriers of the rhBMP-2, using decortication surgical technique in Wistar rats as experimental model.
    Micron (Oxford, England : 1993), 2008, Volume: 39, Issue:7

    Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Chitosan; Disease Models, Animal; Drug Carriers; Gels; Glycerides; Humans; Male; Mandible; Osteogenesis; Random Allocation; Rats; Rats, Wistar; Recombinant Proteins; Transforming Growth Factor beta

2008
[Experimental study on the chitosan-DNA vaccines against campylobacter jejuni invasion].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2007, Volume: 41, Issue:5

    Topics: Animals; Antibodies, Bacterial; Campylobacter Infections; Campylobacter jejuni; Chitosan; Disease Models, Animal; Immunoglobulin A, Secretory; Mice; Mice, Inbred BALB C; Vaccines, DNA

2007
An alternative hemostatic dressing: comparison of CELOX, HemCon, and QuikClot.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:1

    Topics: Animals; Bandages; Blood Pressure; Body Temperature; Chitosan; Disease Models, Animal; Female; Groin; Hemorrhage; Hemostatics; Military Medicine; Powders; Random Allocation; Swine; Treatment Outcome; Wounds and Injuries; Zeolites

2008
Urocanic acid-modified chitosan-mediated PTEN delivery via aerosol suppressed lung tumorigenesis in K-ras(LA1) mice.
    Cancer gene therapy, 2008, Volume: 15, Issue:5

    Topics: Administration, Inhalation; Aerosols; Animals; Chitosan; Disease Models, Animal; Gene Deletion; Genes, ras; Genetic Vectors; Lung Neoplasms; Male; Mice; PTEN Phosphohydrolase; Urocanic Acid

2008
Effects of chitosan-coated pressed calcium sulfate pellet combined with recombinant human bone morphogenetic protein 2 on restoration of segmental bone defect.
    The Journal of craniofacial surgery, 2008, Volume: 19, Issue:2

    Topics: Animals; Bone Diseases; Bone Marrow; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Bone Substitutes; Bony Callus; Calcium Sulfate; Chitosan; Coated Materials, Biocompatible; Compressive Strength; Connective Tissue; Disease Models, Animal; Osteoblasts; Osteogenesis; Pliability; Rabbits; Radius; Recombinant Proteins; Time Factors; Transforming Growth Factor beta

2008
Reduction in postsurgical adhesion formation after cardiac surgery in a rabbit model using N,O-carboxymethyl chitosan to block cell adherence.
    The Journal of thoracic and cardiovascular surgery, 2008, Volume: 135, Issue:4

    Topics: Administration, Topical; Animals; Biocompatible Materials; Cardiac Surgical Procedures; Cells, Cultured; Chitosan; Disease Models, Animal; Female; Fibroblasts; Gels; Macrophages; Rabbits; Solutions; Tissue Adhesions

2008
Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis.
    The Laryngoscope, 2008, Volume: 118, Issue:6

    Topics: Animals; Biocompatible Materials; Chitosan; Chronic Disease; Dextrans; Disease Models, Animal; Endoscopy; Epithelium; Gels; Mucous Membrane; Polyethylene Glycols; Postoperative Complications; Random Allocation; Recombinant Proteins; Sheep; Sinusitis; Thromboplastin; Tissue Adhesions; Wound Healing

2008
A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Jun-24, Volume: 128, Issue:3

    Topics: Animals; Atherosclerosis; Binding Sites; Carbocyanines; Cattle; Cells, Cultured; Chitosan; Disease Models, Animal; Endothelial Cells; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Nanoparticles; Particle Size; Peptides; Protein Binding; Receptors, LDL; Spectroscopy, Near-Infrared; Staining and Labeling; Time Factors; Tumor Necrosis Factor-alpha

2008
Effect of different biomedical membranes on alkali-burned cornea.
    Ophthalmic research, 2008, Volume: 40, Issue:6

    Topics: Animals; Burns, Chemical; Chitosan; Collagen; Corneal Diseases; Disease Models, Animal; Epithelium, Corneal; Eye Burns; Lactic Acid; Membranes, Artificial; Polyesters; Polymers; Rabbits; Sodium Hydroxide; Wound Healing

2008
Osteoconductive properties of methylpyrrolidinone chitosan in an animal model.
    Biomaterials, 1993, Volume: 14, Issue:12

    Topics: Animals; Bone Conduction; Bone Development; Bone Diseases; Bone Regeneration; Chitin; Chitosan; Disease Models, Animal; Female; Light; Microscopy; Microscopy, Electron; Osteoblasts; Pyrrolidinones; Rabbits; Tibia

1993
Prevention of postsurgical adhesions with N,O-carboxymethyl chitosan: examination of the most efficacious preparation and the effect of N,O-carboxymethyl chitosan on postsurgical healing.
    Surgery, 1997, Volume: 121, Issue:3

    Topics: Abdomen; Anastomosis, Surgical; Animals; Aorta; Aortic Diseases; Chitin; Chitosan; Dermatologic Surgical Procedures; Disease Models, Animal; Intestinal Diseases; Intestine, Large; Male; Postoperative Complications; Postoperative Period; Rats; Rats, Sprague-Dawley; Skin; Tissue Adhesions; Wound Healing

1997
Is the dog a useful model for accelerated calcification study of cardiovascular bioprostheses?
    Artificial organs, 1997, Volume: 21, Issue:5

    Topics: Animals; Aorta, Thoracic; Biocompatible Materials; Bioprosthesis; Calcinosis; Cattle; Chelating Agents; Chitin; Chitosan; Coronary Circulation; Disease Models, Animal; Dogs; Glutaral; Heart Valve Diseases; Heart Valve Prosthesis; Swine

1997
Effects of chitosan-coated dialdehyde cellulose, a newly developed oral adsorbent, on glomerulonephritis induced by anti-Thy-1 antibody in rats.
    Nephron, 1998, Volume: 78, Issue:4

    Topics: Adsorption; Animals; Antibodies, Monoclonal; Blood Urea Nitrogen; Cellulose; Chitin; Chitosan; Disease Models, Animal; Glomerulonephritis, Membranoproliferative; Kidney; Male; Mice; Mice, Inbred BALB C; Proteinuria; Rats; Rats, Inbred WKY; Thy-1 Antigens

1998
Dietary chitosan inhibits hypercholesterolaemia and atherogenesis in the apolipoprotein E-deficient mouse model of atherosclerosis.
    Atherosclerosis, 1998, Volume: 138, Issue:2

    Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteriosclerosis; Body Weight; Chitin; Chitosan; Diet; Disease Models, Animal; Hypercholesterolemia; Mice; Mice, Knockout

1998
The effect of chitosan (poly-N-acetyl glucosamine) on lingual hemostasis in heparinized rabbits.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1999, Volume: 57, Issue:1

    Topics: Animals; Anticoagulants; Biopolymers; Blood Coagulation Tests; Chitin; Chitosan; Disease Models, Animal; Drug Evaluation, Preclinical; Hemostasis; Hemostatics; Heparin; Oral Hemorrhage; Rabbits; Time Factors; Tongue

1999
Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.
    Nature medicine, 1999, Volume: 5, Issue:4

    Topics: 2S Albumins, Plant; Administration, Oral; Anaphylaxis; Animals; Antibodies; Antigens, Plant; Arachis; Chitin; Chitosan; Disease Models, Animal; DNA, Plant; Gene Expression; Genes, Plant; Glycoproteins; Histamine; Immunoglobulin E; Mice; Mice, Inbred AKR; Particle Size; Plant Proteins; Transformation, Genetic; Vaccines, DNA

1999
Validation of a pharmacokinetic model of colon-specific drug delivery and the therapeutic effects of chitosan capsules containing 5-aminosalicylic acid on 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:10

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chitin; Chitosan; Colitis; Colon; Disease Models, Animal; Drug Carriers; Male; Mesalamine; Models, Biological; Rats; Rats, Wistar; Reproducibility of Results; Sulfasalazine; Trinitrobenzenesulfonic Acid

1999
Antitumour activity and side effects of combined treatment with chitosan and cisplatin in sarcoma 180-bearing mice.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Chelating Agents; Chitin; Chitosan; Cisplatin; Disease Models, Animal; Infusions, Parenteral; Male; Mice; Mice, Inbred ICR; Sarcoma 180

2000
[The effect of chitosan in prevention of fibrous scar tissue formation after laminectomy].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1998, Volume: 36, Issue:6

    Topics: Animals; Chitosan; Cicatrix; Disease Models, Animal; Epidural Space; Fats; Female; Hyaluronic Acid; Laminectomy; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Tissue Adhesions

1998
[Experimental and clinical study of gentamicin-loaded chitosan drug delivery system].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2000, Volume: 38, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Chitin; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Gentamicins; Osteomyelitis; Rabbits

2000
Antidiabetic action of low molecular weight chitosan in genetically obese diabetic KK-Ay mice.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Chitin; Chitosan; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Drinking; Eating; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred ICR; Molecular Weight; Obesity; Triglycerides

2002
The hemostatic effect of deacetylated chitin membrane on peritoneal injury in rabbit model.
    Surgery today, 1992, Volume: 22, Issue:4

    Topics: Adolescent; Animals; Ascitic Fluid; Blood Loss, Surgical; Chitin; Chitosan; Cricetinae; Disease Models, Animal; Hemostatics; Humans; Liver; Macrophages; Male; Peritoneum; Plasminogen Activators; Protease Inhibitors; Rabbits

1992
Effect of chitosan on lingual hemostasis in rabbits with platelet dysfunction induced by epoprostenol.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1992, Volume: 50, Issue:1

    Topics: Analysis of Variance; Animals; Bleeding Time; Blood Coagulation Tests; Blood Platelet Disorders; Chitin; Chitosan; Disease Models, Animal; Epoprostenol; Hemostatics; Rabbits; Tongue

1992