chitosan has been researched along with Colorectal Neoplasms in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (4.69) | 29.6817 |
| 2010's | 36 (56.25) | 24.3611 |
| 2020's | 25 (39.06) | 2.80 |
| Authors | Studies |
|---|---|
| Saczko, J; Tsirigotis-Maniecka, M; Wezgowiec, J; Wieckiewicz, M; Wilk, KA | 1 |
| Gaballo, A; Gervaso, F; Gigli, G; Morello, G; Moroni, L; Polini, A; Quarta, A | 1 |
| Li, Y; Wu, D; Xu, S; Yan, Q; Yang, G; Yang, Y; Zhang, W; Zhu, L | 1 |
| Abbaszadeh-Goudarzi, K; Ahmadi, M; Ansari Dezfouli, E; Chalajour, H; Ebrahimi, F; Gholizadeh Navashenaq, J; Hashemi, V; Hassannia, H; Hojjat-Farsangi, M; Izadi, S; Jadidi-Niaragh, F; Karoon Kiani, F; Karpisheh, V; Mahmoud Salehi Khesht, A; Mohammadi, M; Mortazavi Bulus, M; Nasr Esfahani, M; Shahmohammadi Farid, S; Soleimani, A | 1 |
| Araújo, A; Leão, P; Martins, A; Neves, NM; Oliveira, A; Reis, RL; Rodrigues, LC; Silva, CS | 1 |
| Agrawal, G; Bharadwaj, R; Gupta, A; Ranganath, P; Silverman, N; Sood, A | 1 |
| Almeida, A; Castro, F; Lúcio, M; Resende, C; Sarmento, B; Schwartz, S | 1 |
| Chen, Q; Deng, R; Gui, S; Guo, Y; Jin, X; Lu, X; Su, L; Wang, J; Wang, S; Wang, Z; Xin, H; Xu, Y; Zeng, J; Zhang, L; Zhu, B | 1 |
| Ahmad, A; Altwaijry, N; Asghar, MN; Khan, MS; Khan, R; Prakash, R; Raza, SS | 1 |
| Gustiananda, M; Hartrianti, P; Juanssilfero, AB; Leonard, TE; Liko, AF; Putra, ABN | 1 |
| Abdullah, NH; Ali, RR; Jie, CJ; Kia, P; Lee-Kiun, MS; Moeini, H; Shameli, K; Teow, SY; Yusefi, M | 1 |
| Ali, DS; Anwer, ET; Othman, HO | 1 |
| Abdelgawad, MA; Ahmed, YM; Ali, HM; Alsaidan, OA; El-Say, KM; Elkomy, MH; Elmowafy, M; Gomaa, HAM; Hendawy, OM; Shalaby, K | 1 |
| Mirian, M; Sadeghi, HMM; Shariati, L; Shirani-Bidabadi, S; Tavazohi, N; Varshosaz, J | 1 |
| Barredo-Vacchelli, GR; Birocco, AM; Blachman, A; Calabrese, GC; Camperi, SA; Cenci, G; Curcio, S; Gianvincenzo, PD; Moya, S; Rodriguez, JA; Sosnik, A | 1 |
| Lin, WJ; Pai, FT | 1 |
| Bhattacharya, S; Hatware, K; Jain, A; Manthalkar, L; Phatak, N; Shah, D; Sreelaya, P | 1 |
| Chen, X; Liu, Y; Mu, Y; Sun, M; Tian, M; Wang, F; Wang, T | 1 |
| Bhattacharya, S | 1 |
| Li, Y; Wang, H; Wu, D; Wu, R; Xu, S; Yang, G; Zhang, X; Zhu, L | 1 |
| Durand, A; Inphonlek, S; Léonard, M; Sunintaboon, P | 1 |
| Gao, S; Liu, C; Liu, S; Qu, H; Shui, S; Yan, L; Zheng, L | 1 |
| Cui, SH; Li, PP; Qian, HG; Wang, CH; Wang, JC; Wei, W; Yan, Y; Zhang, HT; Zhang, Q | 1 |
| Akhter, DT; Bell, C; Dos Santos, AM; Fletcher, N; Gremião, MPD; Houston, ZH; Meneguin, AB; Thurecht, KJ | 1 |
| Cheruku, SP; Day, CM; Gadag, S; Garg, S; Kumar, N; Manandhar, S; Mehta, CH; Narayan, R; Nayak, UY; Nayak, Y; Pai, KSR; Raichur, AM; Suresh, A | 1 |
| Aghebati-Maleki, L; Hassannia, H; Hojjat-Farsangi, M; Jadidi-Niaragh, F; Jafari, R; Karpisheh, V; Mahmoodpoor, A; Majidi Zolbanin, N; Melnikova, LA; Mohammadi, M; Olegovna Zekiy, A; Sahami Gilan, P; Salehi Khesht, AM | 1 |
| Ao, J; Guan, Q; Jin, X; Li, C; Li, P; Liang, X; Pan, R; Wang, K; Xu, L; Zhang, C; Zhu, X | 1 |
| Chakraborty, I; Jimenez, J; Mascharak, PK | 1 |
| El-Maraghy, SA; ElMeshad, AN; Hammam, OA; Motawi, TK; Nady, OM | 1 |
| Elgendy, H; Elhawary, S; Kamel, KM; Khalil, IA; Rateb, ME | 1 |
| Bae, WK; Cho, KJ; Cho, S; Kang, SH; Lee, SJ; Lee, YK; Park, IK; Revuri, V | 1 |
| Haj, NQ; Hussain, KS; Mohammed, MO | 1 |
| Cao, D; Chen, L; Fang, JK; Guo, LL; Kuang, YT; Li, LB; Lu, XG; Wang, SL; Zhang, LF; Zhang, YS | 1 |
| Atyabi, F; Javan, B; Shahbazi, M | 1 |
| Cha, B; Hwang, SC; Jeong, YI; Kang, DH; Kim, J; Lee, HL; Nah, JW | 1 |
| Alomrani, AH; Ashour, AE; Badran, MM; Harisa, GI; Kumar, A; Yassin, AE | 1 |
| Byeon, JH; Kim, JO; Ku, SK; Ou, W; Thapa, RK; Yong, CS | 1 |
| Asiri, SM; Bozkurt, A; Khan, FA | 1 |
| Dawaba, AM; Dawaba, HM | 1 |
| Almeida, R; Barbosa, MA; Castro, F; Gonçalves, RM; Oliveira, MJ; Pereira, CL; Pereira, F; Pinto, ML; Santos, SG; Silva, AM | 1 |
| Atyabi, F; Dinarvand, R; Esfandyari-Manesh, M; Ghasemi, Z; Mottaghitalab, F; Sayari, E | 1 |
| Chatsudthipong, V; Mattaveewong, T; Moonwiriyakit, A; Muanprasat, C; Pichyangkura, R; Pongkorpsakol, P; Satitsri, S; Wongkrasant, P | 1 |
| Chiang, BH; Udompornmongkol, P | 1 |
| Jain, A; Jain, R; Jain, S; Kohli, DV | 1 |
| Chanchai, S; Chatsudthipong, V; Mattaveewong, T; Muanprasat, C; Pichyangkura, R; Wongkrasant, P | 1 |
| Ahmadi, M; Atyabi, F; Babaloo, Z; Baradaran, B; Jadidi-Niaragh, F; Mohammadi, H; Siahmansouri, H; Somi, MH; Yousefi, M | 1 |
| Alkhader, E; Billa, N; Roberts, CJ | 1 |
| Chandrasekaran, R; Cheng, W; Hourigan, K; Janmaleki, M; Pachenari, M; Seyedpour, SM; Taranejoo, S | 1 |
| Chen, Y; Fan, J; Fu, SZ; Wang, SS; Wu, JB; Xu, S; Yang, JP; Yang, LL; Yun, Q | 1 |
| Badran, MM; Ghannam, MM; Mady, MM; Shakeel, F | 1 |
| Aghebati-Maleki, L; Baradaran, B; Hosseinpour-Feizi, MA; Jadidi-Niaragh, F; Kafil, HS; Sadreddini, S; Safaralizadeh, R; Shanehbandi, D; Younesi, V; Yousefi, M | 1 |
| Lai, PS; Lin, FH; Lou, PJ; Peng, CL; Shieh, MJ; Wei, MF; Yang, SJ; Yao, CJ; Young, TH | 1 |
| Barve, J; Beg, AM; Ganesh, N; Jain, A; Jain, SK | 1 |
| Chen, C; Ding, Y; Hu, Y; Jiang, X; Li, R; Yan, E | 1 |
| Guo, R; Jiang, X; Li, R; Liu, B; Qian, H; Zhang, L | 1 |
| Lin, FH; Shieh, MJ; Tsai, HM; Tsai, KC; Wei, MF; Wong, JM; Yang, SJ | 1 |
| Greiner, JW; Hance, KW; Rogers, CJ; Schlom, J; Zaharoff, DA | 1 |
| Chin, HC; Lin, CF; Lin, FH; Shieh, MJ; Tsai, HM; Wong, JM; Yang, SJ | 1 |
| Hu, FQ; Huang, J; Liu, L; Qiu, F; Wang, K; Wang, XL; Wu, XG; Zhang, T; Zhu, YL | 1 |
| Chen, C; Chen, J; Gao, B; Gu, X; Guo, L; Hu, X; Kuang, Y; Wang, S; Wang, Y; Xu, Q; Zhang, B; Zhang, J | 1 |
| Chen, Z; Hu, F; Huang, J; Liu, L; Ni, C; Wang, K; Wang, X; Wu, P; Zhang, J; Zhang, T | 1 |
| Ataman-Önal, Y; Chevolot, Y; Choquet-Kastylevsky, G; Delair, T; Dugas, V; Géhin, T; Laporte, V; Laurenceau, E; Souteyrand, E; Xanthopoulos, N; Yang, Z | 1 |
| Abdelghany, SM; Burrows, JF; Deacon, J; Donnelly, RF; Fay, F; Gormley, JA; Jaworski, J; Longley, DB; McLaughlin, KM; Schmid, D; Scott, CJ | 1 |
| Gati, I; Haupt, S; Kleinstern, J; Rubinstein, A; Zioni, T | 1 |
1 review(s) available for chitosan and Colorectal Neoplasms
| Article | Year |
|---|---|
The Advances in Chitosan-based Drug Delivery Systems for Colorectal Cancer: A Narrative Review.
Topics: Antineoplastic Agents; Chitosan; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; Nanoparticles | 2023 |
63 other study(ies) available for chitosan and Colorectal Neoplasms
| Article | Year |
|---|---|
Microparticles vs. Macroparticles as Curcumin Delivery Vehicles: Structural Studies and Cytotoxic Effect in Human Adenocarcinoma Cell Line (LoVo).
Topics: Adenocarcinoma; Alginates; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Curcumin; Drug Carriers; Drug Delivery Systems; Gelatin; Humans; Hydrogels; Microspheres; Particle Size | 2021 |
A thermo-sensitive chitosan/pectin hydrogel for long-term tumor spheroid culture.
Topics: Chitosan; Colorectal Neoplasms; HCT116 Cells; Humans; Hydrogels; Pectins | 2021 |
A biocompatible superparamagnetic chitosan-based nanoplatform enabling targeted SN-38 delivery for colorectal cancer therapy.
Topics: Animals; Antineoplastic Agents; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; HCT116 Cells; Human Umbilical Vein Endothelial Cells; Humans; Irinotecan; Mice; Mice, Nude; Nanoparticles | 2021 |
Simultaneous silencing of the A2aR and PD-1 immune checkpoints by siRNA-loaded nanoparticles enhances the immunotherapeutic potential of dendritic cell vaccine in tumor experimental models.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Chitosan; Colorectal Neoplasms; Combined Modality Therapy; Dendritic Cells; Female; Humans; Immunotherapy; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Programmed Cell Death 1 Receptor; Receptor, Adenosine A2A; RNA, Small Interfering; Tumor Cells, Cultured; Vaccines; Xenograft Model Antitumor Assays | 2022 |
Metronidazole Delivery Nanosystem Able To Reduce the Pathogenicity of Bacteria in Colorectal Infection.
Topics: Anti-Bacterial Agents; Bacteria; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; Escherichia coli; Humans; Metronidazole; Nanoparticles; Virulence | 2022 |
Biodegradable disulfide crosslinked chitosan/stearic acid nanoparticles for dual drug delivery for colorectal cancer.
Topics: Animals; Chitosan; Colorectal Neoplasms; Curcumin; Disulfides; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Mice; Nanoparticles; Stearic Acids; Tissue Distribution | 2022 |
Oral delivery of camptothecin-loaded multifunctional chitosan-based micelles is effective in reduce colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Camptothecin; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Drug Carriers; Humans; Micelles; Oleic Acid | 2022 |
Mitochondria-targeting folic acid-modified nanoplatform based on mesoporous carbon and a bioactive peptide for improved colorectal cancer treatment.
Topics: Carbon; Caspase 3; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; Folic Acid; Formaldehyde; Humans; Mitochondria; Nanoparticles; Peptides; Phloroglucinol; Tumor Suppressor Protein p53 | 2022 |
Nanoparticle-Mediated PRDX2 Inhibition for Specific Targeting of CHK2-Null Colorectal Cancer.
Topics: Caco-2 Cells; Chitosan; Colorectal Neoplasms; Humans; Nanoparticles; Peroxiredoxins | 2022 |
Thiolated pectin-chitosan composites: Potential mucoadhesive drug delivery system with selective cytotoxicity towards colorectal cancer.
Topics: Biocompatible Materials; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; HEK293 Cells; Humans; Pectins; Polyelectrolytes | 2023 |
Chitosan coated magnetic cellulose nanowhisker as a drug delivery system for potential colorectal cancer treatment.
Topics: Cellulose; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; Drug Liberation; Fluorouracil; Humans; Magnetic Phenomena; Nanocomposites; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2023 |
Exploring the potential of quercetin/aspirin-loaded chitosan nanoparticles coated with Eudragit L100 in the treatment of induced-colorectal cancer in rats.
Topics: Animals; Aspirin; Chitosan; Colorectal Neoplasms; Drug Carriers; Nanoparticles; Particle Size; Quercetin; Rats | 2023 |
Gene network analysis of oxaliplatin-resistant colorectal cancer to target a crucial gene using chitosan/hyaluronic acid/protamine polyplexes containing CRISPR-Cas9.
Topics: Chitosan; Colorectal Neoplasms; CRISPR-Cas Systems; Gene Regulatory Networks; Humans; Hyaluronic Acid; Oxaliplatin; Protamines | 2023 |
Dermatan Sulfate/Chitosan Nanoparticles Loaded with an Anti-Inflammatory Peptide Increase the Response of Human Colorectal Cancer Cells to 5-Fluorouracil.
Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Dermatan Sulfate; Fluorouracil; Humans; Nanoparticles; NF-kappa B; Peptides | 2023 |
Synergistic cytotoxicity of irinotecan combined with polysaccharide-based nanoparticles for colorectal carcinoma.
Topics: Chitosan; Colorectal Neoplasms; Fluorescein-5-isothiocyanate; Humans; Irinotecan; Nanoparticles | 2023 |
Fabrication of D-α-tocopheryl polyethylene glycol 1000 succinates and human serum albumin conjugated chitosan nanoparticles of bosutinib for colon targeting application; in vitro-in vivo investigation.
Topics: Animals; Chitosan; Colorectal Neoplasms; Drug Carriers; Humans; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Rats; Succinates; Vitamin E | 2023 |
Gastric environment-stable oral nanocarriers for in situ colorectal cancer therapy.
Topics: Administration, Oral; Adsorption; Caco-2 Cells; Chitosan; Colorectal Neoplasms; Curcumin; Deoxycholic Acid; Drug Carriers; Drug Liberation; Drug Stability; Gastric Mucosa; Hemolysis; Humans; Intestinal Absorption; Materials Testing; Nanoparticles; Temperature | 2019 |
Fabrication and characterization of chitosan-based polymeric nanoparticles of Imatinib for colorectal cancer targeting application.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Drug Carriers; Hemolysis; Humans; Imatinib Mesylate; Male; Molecular Structure; Nanoparticles; Polymers; Protein Kinase Inhibitors; Rats; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis | 2020 |
Superparamagnetic chitosan nanocomplexes for colorectal tumor-targeted delivery of irinotecan.
Topics: Animals; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Colorectal Neoplasms; Drug Carriers; Drug Liberation; Drug Stability; Female; HCT116 Cells; Human Umbilical Vein Endothelial Cells; Humans; Irinotecan; Magnetic Iron Oxide Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Particle Size; Polyelectrolytes; Polyglutamic Acid; Surface Properties; Tissue Distribution; Topoisomerase I Inhibitors | 2020 |
Chitosan/carboxymethylcellulose-stabilized poly(lactide-co-glycolide) particles as bio-based drug delivery carriers.
Topics: Antineoplastic Agents; Carboxymethylcellulose Sodium; Cell Proliferation; Chitosan; Colorectal Neoplasms; Curcumin; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Molecular Structure; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Tension; Tumor Cells, Cultured | 2020 |
Small interfering RNA-loaded chitosan hydrochloride/carboxymethyl chitosan nanoparticles for ultrasound-triggered release to hamper colorectal cancer growth in vitro.
Topics: Chitosan; Colorectal Neoplasms; Delayed-Action Preparations; Drug Carriers; HT29 Cells; Humans; Nanoparticles; RNA, Small Interfering; Ultrasonic Waves | 2020 |
Biological activities of siRNA-loaded lanthanum phosphate nanoparticles on colorectal cancer.
Topics: Animals; Chitosan; Colorectal Neoplasms; Humans; Lanthanum; Mice; Mice, Inbred C57BL; Nanoparticles; Phosphates; RNA, Small Interfering | 2020 |
Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Chitosan; Colon; Colorectal Neoplasms; Drug Carriers; Drug Compounding; Drug Liberation; Female; Fluorouracil; Gastrointestinal Microbiome; Humans; Intestinal Absorption; Intestinal Mucosa; Mice; Models, Animal; Nanoparticles; Particle Size; Pectins; Proof of Concept Study; Starch; Tissue Distribution | 2021 |
Chitosan-glucuronic acid conjugate coated mesoporous silica nanoparticles: A smart pH-responsive and receptor-targeted system for colorectal cancer therapy.
Topics: Animals; Capecitabine; Cell Line, Tumor; Cell Survival; Chitosan; Coated Materials, Biocompatible; Colorectal Neoplasms; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Female; Glucuronic Acid; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Nanoparticles; Particle Size; Porosity; Rats; Rats, Wistar; Silicon Dioxide; Xenograft Model Antitumor Assays | 2021 |
Blockade of CD73 using siRNA loaded chitosan lactate nanoparticles functionalized with TAT-hyaluronate enhances doxorubicin mediated cytotoxicity in cancer cells both in vitro and in vivo.
Topics: 5'-Nucleotidase; Animals; Antibiotics, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chitosan; Colorectal Neoplasms; Doxorubicin; Drug Compounding; Female; GPI-Linked Proteins; Hyaluronic Acid; Lactates; Mice; Mice, Inbred BALB C; Nanoparticles; Nanotechnology; Neoplasm Invasiveness; Neovascularization, Pathologic; RNA, Small Interfering; RNAi Therapeutics; tat Gene Products, Human Immunodeficiency Virus | 2021 |
Hydrogen Peroxide-Responsive Nanoprobe Assists Circulating Tumor Cell Identification and Colorectal Cancer Diagnosis.
Topics: Cell Membrane Permeability; Chitosan; Colorectal Neoplasms; Female; Fluorescence; Humans; Hydrogen Peroxide; Micelles; Molecular Imaging; Molecular Probes; Neoplastic Cells, Circulating | 2017 |
CO-Induced apoptotic death of colorectal cancer cells by a luminescent photoCORM grafted on biocompatible carboxymethyl chitosan.
Topics: Apoptosis; Biocompatible Materials; Carbon Monoxide; Caspase 3; Caspase 7; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Coordination Complexes; Crystallography, X-Ray; HT29 Cells; Humans; Microscopy, Confocal; Molecular Conformation; Rhenium; Spectroscopy, Fourier Transform Infrared | 2017 |
Cromolyn chitosan nanoparticles as a novel protective approach for colorectal cancer.
Topics: Animals; Antineoplastic Agents; beta Catenin; Chitosan; Colorectal Neoplasms; Cromolyn Sodium; Dimethylhydrazines; Drug Carriers; Drug Liberation; Lipid Peroxidation; Male; Nanoparticles; Particle Size; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Signal Transduction | 2017 |
Chitosan-Coated Cinnamon/Oregano-Loaded Solid Lipid Nanoparticles to Augment 5-Fluorouracil Cytotoxicity for Colorectal Cancer: Extract Standardization, Nanoparticle Optimization, and Cytotoxicity Evaluation.
Topics: Antineoplastic Agents; Cell Survival; Chitosan; Cinnamomum zeylanicum; Colorectal Neoplasms; Drug Carriers; Fluorouracil; HCT116 Cells; Humans; Lipids; Nanoparticles; Origanum; Plant Extracts | 2017 |
Oral siRNA Delivery to Treat Colorectal Liver Metastases.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chitosan; Colorectal Neoplasms; Dogs; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Gold; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles; RNA, Small Interfering; Taurocholic Acid | 2017 |
Preparation and Bioactivity Assessment of Chitosan-1-Acetic Acid-5-Flurouracil Conjugates as Cancer Prodrugs.
Topics: Acetic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Fluorouracil; Humans; Prodrugs; Rabbits | 2017 |
Optimization of Transforming Growth Factor-β1 siRNA Loaded Chitosan-Tripolyphosphate Nanoparticles for the Treatment of Colorectal Cancer Hepatic Metastasis in a Mouse Model.
Topics: Animals; Chitosan; Colorectal Neoplasms; Disease Models, Animal; Drug Carriers; Liver; Liver Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; RNA Interference; RNA, Small Interfering; Transforming Growth Factor beta1 | 2016 |
Hypoxia-inducible bidirectional shRNA expression vector delivery using PEI/chitosan-TBA copolymers for colorectal Cancer gene therapy.
Topics: Apoptosis; beta Catenin; Cell Cycle; Chitosan; Colorectal Neoplasms; Gene Transfer Techniques; Genes, bcl-2; Genetic Therapy; Genetic Vectors; HT29 Cells; Humans; Hypoxia; Nanoparticles; Particle Size; Polymers; RNA, Small Interfering; Sulfhydryl Compounds | 2018 |
Redox- and pH-Responsive Nanoparticles Release Piperlongumine in a Stimuli-Sensitive Manner to Inhibit Pulmonary Metastasis of Colorectal Carcinoma Cells.
Topics: A549 Cells; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Dioxolanes; Drug Carriers; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Nanoparticles; Oxidation-Reduction; Polyethylene Glycols | 2018 |
Novel docetaxel chitosan-coated PLGA/PCL nanoparticles with magnified cytotoxicity and bioavailability.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Survival; Chitosan; Colorectal Neoplasms; Delayed-Action Preparations; Docetaxel; Drug Carriers; Drug Compounding; Drug Liberation; Dynamic Light Scattering; HT29 Cells; Humans; Injections, Intraperitoneal; Lactic Acid; Male; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Taxoids; Technology, Pharmaceutical | 2018 |
Plug-and-Play Nanorization of Coarse Black Phosphorus for Targeted Chemo-photoimmunotherapy of Colorectal Cancer.
Topics: Antibiotics, Antineoplastic; Cell Proliferation; Cell Survival; Chitosan; Colorectal Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Immunotherapy; Phosphorus; Photochemical Processes; Phototherapy; Polyethylene Glycols; Programmed Cell Death 1 Receptor; RNA, Small Interfering; Tumor Cells, Cultured | 2018 |
Synthesis of chitosan nanoparticles, chitosan-bulk, chitosan nanoparticles conjugated with glutaraldehyde with strong anti-cancer proliferative capabilities.
Topics: Antineoplastic Agents; Chitosan; Colorectal Neoplasms; Drug Carriers; Glutaral; HCT116 Cells; Humans; Nanoparticles | 2018 |
Application of Optimization Technique to Develop Nano-Based Carrier of Nigella Sativa Essential Oil: Characterization and Assessment.
Topics: Anti-Bacterial Agents; Benzoic Acid; Chemistry, Pharmaceutical; Chitosan; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; HCT116 Cells; Humans; Inhibitory Concentration 50; Male; Nanoparticles; Nigella sativa; Oils, Volatile; Particle Size; PC-3 Cells; Prostatic Neoplasms; Staphylococcus aureus | 2019 |
Chitosan/poly(γ-glutamic acid) nanoparticles incorporating IFN-γ for immune response modulation in the context of colorectal cancer.
Topics: Cell Proliferation; Cell Survival; Chitosan; Colorectal Neoplasms; Drug Carriers; Drug Liberation; Humans; Immunologic Factors; Interferon-gamma; Macrophages; Nanoparticles; Neoplasm Invasiveness; Phosphorylation; Polyglutamic Acid; STAT1 Transcription Factor; T-Lymphocytes; Tumor Microenvironment | 2019 |
Aptamer decorated hyaluronan/chitosan nanoparticles for targeted delivery of 5-fluorouracil to MUC1 overexpressing adenocarcinomas.
Topics: Adenocarcinoma; Animals; Aptamers, Nucleotide; Chitosan; CHO Cells; Colorectal Neoplasms; Cricetinae; Cricetulus; Fluorouracil; HT29 Cells; Humans; Hyaluronic Acid; Mucin-1; Nanoparticles | 2015 |
Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders.
Topics: AMP-Activated Protein Kinases; Animals; Azoxymethane; beta Catenin; Calcium; Caspase 3; Cell Line, Tumor; Chitosan; Cholera Toxin; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial Cells; Gastrointestinal Agents; Gene Expression Regulation; Humans; Inositol 1,4,5-Trisphosphate Receptors; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Receptors, Calcium-Sensing; Receptors, G-Protein-Coupled; Signal Transduction; Type C Phospholipases | 2015 |
Curcumin-loaded polymeric nanoparticles for enhanced anti-colorectal cancer applications.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Colon; Colorectal Neoplasms; Curcumin; Drug Carriers; Gum Arabic; Humans; Hydrolysis; Nanoparticles; Rectum | 2015 |
Coated chitosan nanoparticles encapsulating caspase 3 activator for effective treatment of colorectral cancer.
Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Caspase 3; Chitosan; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Enzyme Activation; Formazans; Humans; Nanoparticles; Particle Size; Polymethacrylic Acids; Rabbits; Staurosporine; Tetrazolium Salts | 2015 |
Chitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-κB and mTOR signaling.
Topics: AMP-Activated Protein Kinases; Animals; Anticarcinogenic Agents; Chitosan; Colitis; Colon; Colorectal Neoplasms; Cyclin D1; Disease Models, Animal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; NF-kappa B; Oligosaccharides; TOR Serine-Threonine Kinases; Tumor Burden | 2016 |
Effects of HMGA2 siRNA and doxorubicin dual delivery by chitosan nanoparticles on cytotoxicity and gene expression of HT-29 colorectal cancer cell line.
Topics: Adenocarcinoma; Antineoplastic Agents; Cadherins; Chemistry, Pharmaceutical; Chitosan; Colorectal Neoplasms; Doxorubicin; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Stability; HMGA2 Protein; HT29 Cells; Humans; Matrix Metalloproteinase 9; Nanoparticles; Particle Size; RNA, Messenger; RNA, Small Interfering; Vimentin | 2016 |
Mucoadhesive Chitosan-Pectinate Nanoparticles for the Delivery of Curcumin to the Colon.
Topics: Antineoplastic Agents; Biocompatible Materials; Chitosan; Colon; Colorectal Neoplasms; Curcumin; Drug Carriers; Drug Delivery Systems; Humans; Nanoparticles | 2017 |
Dual effect of F-actin targeted carrier combined with antimitotic drug on aggressive colorectal cancer cytoskeleton: Allying dissimilar cell cytoskeleton disrupting mechanisms.
Topics: Actins; Albendazole; Antimitotic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Colorectal Neoplasms; Cytoskeleton; Drug Carriers; Drug Liberation; Elasticity; Humans; Nanoparticles; Viscosity | 2016 |
Use of 5-Fluorouracil Loaded Micelles and Cisplatin in Thermosensitive Chitosan Hydrogel as an Efficient Therapy against Colorectal Peritoneal Carcinomatosis.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Chitosan; Cisplatin; Colorectal Neoplasms; Disease Models, Animal; Drug Liberation; Female; Fluorouracil; Hydrogel, Polyethylene Glycol Dimethacrylate; Immunohistochemistry; Injections; Ki-67 Antigen; Liver Neoplasms; Lung Neoplasms; Mice, Inbred BALB C; Micelles; Peritoneal Neoplasms; Rheology; Temperature | 2017 |
Preparation and characterization of polymeric nanoparticles surface modified with chitosan for target treatment of colorectal cancer.
Topics: Chitosan; Colorectal Neoplasms; Drug Liberation; Fluorouracil; HT29 Cells; Humans; Kinetics; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Surface Properties | 2017 |
Chitosan nanoparticles as a dual drug/siRNA delivery system for treatment of colorectal cancer.
Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Chitosan; Colorectal Neoplasms; Disease Models, Animal; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Humans; Mice; Nanoparticles; RNA, Small Interfering; Spectroscopy, Fourier Transform Infrared; Wound Healing; Xenograft Model Antitumor Assays | 2017 |
Colorectal cancer cell detection by 5-aminolaevulinic acid-loaded chitosan nano-particles.
Topics: Aminolevulinic Acid; Caco-2 Cells; Chitosan; Colorectal Neoplasms; Endoscopy; Escherichia coli; Humans; Hydrogen-Ion Concentration; Medical Oncology; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Particle Size; Photosensitizing Agents; Polyphosphates | 2009 |
Design and development of ligand-appended polysaccharidic nanoparticles for the delivery of oxaliplatin in colorectal cancer.
Topics: Animals; Calorimetry, Differential Scanning; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; HT29 Cells; Humans; Hyaluronic Acid; Ligands; Mice; Nanoparticles; Organoplatinum Compounds; Oxaliplatin; Radionuclide Imaging; Remission Induction; Spectroscopy, Fourier Transform Infrared; Tissue Distribution; X-Ray Diffraction; Xenograft Model Antitumor Assays | 2010 |
Polymer/silica hybrid hollow nanospheres with pH-sensitive drug release in physiological and intracellular environments.
Topics: Acrylic Resins; Cell Line, Tumor; Cell Survival; Chitosan; Colorectal Neoplasms; Doxorubicin; Drug Carriers; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Microscopy, Electron, Transmission; Nanospheres; Silicon Dioxide | 2009 |
Multifunctional nanocarriers for cell imaging, drug delivery, and near-IR photothermal therapy.
Topics: Cell Line, Tumor; Cell Survival; Chitosan; Cisplatin; Colorectal Neoplasms; Humans; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Models, Theoretical; Nanospheres; Nanotubes; Photochemistry | 2010 |
Folic acid-conjugated chitosan nanoparticles enhanced protoporphyrin IX accumulation in colorectal cancer cells.
Topics: Aminolevulinic Acid; Caco-2 Cells; Carrier Proteins; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Nanoparticles; Protoporphyrins; Receptors, Cell Surface | 2010 |
Intratumoral immunotherapy of established solid tumors with chitosan/IL-12.
Topics: Adjuvants, Immunologic; Animals; Carcinoembryonic Antigen; Cells, Cultured; Chitosan; Colorectal Neoplasms; Cytotoxicity, Immunologic; Immunologic Memory; Immunotherapy; Interleukin-12; Lymphocyte Depletion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Transplantation; Pancreatic Neoplasms; Remission Induction; Tumor Burden | 2010 |
Alginate-folic acid-modified chitosan nanoparticles for photodynamic detection of intestinal neoplasms.
Topics: Alginates; Animals; Biocompatible Materials; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Drug Carriers; Fluoresceins; Folic Acid; Glucuronic Acid; Hexuronic Acids; Humans; Intestinal Neoplasms; Materials Testing; Mice; Mice, Inbred C57BL; Models, Molecular; Nanoparticles; Photochemistry | 2011 |
Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Chitosan; Colorectal Neoplasms; Drug Carriers; Female; HT29 Cells; Humans; Mice; Mice, Nude; Micelles; Microscopy, Confocal; Neoplastic Stem Cells; Organoplatinum Compounds; Oxaliplatin; Spheroids, Cellular; Stearic Acids; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
Prevention of colorectal cancer liver metastasis by exploiting liver immunity via chitosan-TPP/nanoparticles formulated with IL-12.
Topics: Animals; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Colorectal Neoplasms; Injections, Intravenous; Interleukin-12; Liver; Liver Neoplasms; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyphosphates; Surface Properties; Tissue Distribution; Tumor Microenvironment | 2012 |
Novel micelle formulation of curcumin for enhancing antitumor activity and inhibiting colorectal cancer stem cells.
Topics: Animals; Antineoplastic Agents; Body Weight; CD24 Antigen; Cell Survival; Chitosan; Colorectal Neoplasms; Curcumin; Drug Carriers; Drug Stability; Flow Cytometry; Humans; Hyaluronan Receptors; Mice; Micelles; Nanoparticles; Neoplastic Stem Cells; Particle Size; Random Allocation; Solubility; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2012 |
Characterization of three amino-functionalized surfaces and evaluation of antibody immobilization for the multiplex detection of tumor markers involved in colorectal cancer.
Topics: Amines; Antibodies; Biomarkers, Tumor; Chitosan; Colorectal Neoplasms; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Propylamines; Protein Array Analysis; Silanes; Surface Properties | 2013 |
Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles.
Topics: Alginates; Antibodies; Antineoplastic Agents; Biological Transport; Caspase 8; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Glucuronic Acid; Hexuronic Acids; Humans; Nanoparticles; Photochemotherapy; Photosensitizing Agents; Porphyrins; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA Interference; RNA, Small Interfering | 2013 |
Luminal delivery and dosing considerations of local celecoxib administration to colorectal cancer.
Topics: Adhesiveness; Animals; Celecoxib; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Drug Carriers; Feces; Galactans; HT29 Cells; Humans; Inhibitory Concentration 50; Intestinal Mucosa; Intestines; Male; Mannans; Particle Size; Plant Gums; Pyrazoles; Rats; Rats, Sprague-Dawley; Solubility; Sulfonamides | 2006 |