chir-99021 has been researched along with Ovarian-Neoplasms* in 1 studies
1 other study(ies) available for chir-99021 and Ovarian-Neoplasms
Article | Year |
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GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity.
Maturation of human natural killer (NK) cells as defined by accumulation of cell-surface expression of CD57 is associated with increased cytotoxic character and TNF and IFNγ production upon target-cell recognition. Notably, multiple studies point to a unique role for CD57 Topics: A549 Cells; Animals; Antibody-Dependent Cell Cytotoxicity; Cell Line, Tumor; Enzyme Inhibitors; Female; Glycogen Synthase Kinase 3; Humans; Immunotherapy, Adoptive; Interleukin-15; K562 Cells; Killer Cells, Natural; Mice; Mice, Inbred NOD; Ovarian Neoplasms; Pyridines; Pyrimidines; Xenograft Model Antitumor Assays | 2017 |