chetomin has been researched along with Glial Cell Tumors in 2 studies
chetomin: C31H30N6O6S4, similar to epipolythiodioxopiperazines
chetomin : An organic heteropentacyclic compound of the class of epipolythiodioxopiperazine. Isolated from Chaetomium globosum and Farrowia seminuda, it exhibits immunosuppressive activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although siRNA and chetomin show distinct modes of action, both attenuated the hypoxia-induced radioresistance of malignant glioma cell lines U251MG (DMF10: 1." | 7.76 | HIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression. ( Bache, M; Hahnel, A; Kappler, M; Kessler, J; Rot, S; Vordermark, D; Wichmann, H, 2010) |
| "Although siRNA and chetomin show distinct modes of action, both attenuated the hypoxia-induced radioresistance of malignant glioma cell lines U251MG (DMF10: 1." | 3.76 | HIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression. ( Bache, M; Hahnel, A; Kappler, M; Kessler, J; Rot, S; Vordermark, D; Wichmann, H, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, H | 1 |
| Li, Y | 1 |
| Shu, M | 1 |
| Tang, J | 1 |
| Huang, Y | 1 |
| Zhou, Y | 1 |
| Liang, Y | 1 |
| Yan, G | 1 |
| Kessler, J | 1 |
| Hahnel, A | 1 |
| Wichmann, H | 1 |
| Rot, S | 1 |
| Kappler, M | 1 |
| Bache, M | 1 |
| Vordermark, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metformin and Neo-adjuvant Temozolomide and Hypofractionated Accelerated Limited-margin Radiotherapy Followed by Adjuvant Temozolomide in Patients With Glioblastoma Multiforme (M-HARTT STUDY)[NCT02780024] | Phase 2 | 50 participants (Anticipated) | Interventional | 2015-03-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for chetomin and Glial Cell Tumors
| Article | Year |
|---|---|
Hypoxia-inducible factor-1alpha blocks differentiation of malignant gliomas.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Cobalt; Colforsin; | 2009 |
HIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Carbonic Anhydrase IX; Carbonic Anhydrases; Ce | 2010 |