Page last updated: 2024-08-21

chenodeoxycholic acid and Obesity

chenodeoxycholic acid has been researched along with Obesity in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199023 (46.00)18.7374
1990's5 (10.00)18.2507
2000's2 (4.00)29.6817
2010's15 (30.00)24.3611
2020's5 (10.00)2.80

Authors

AuthorsStudies
Auwerx, J; Gioiello, A; Macchiarulo, A; Natalini, B; Pastorini, E; Pellicciari, R; Pruzanski, M; Roda, A; Rosatelli, E; Sardella, R; Schoonjans, K; Thomas, C1
Fenaux, M; Halcomb, RL; Jones, CT; Romero, FA; Xu, Y1
Amorim, JA; Carvalho, RA; Castela, AC; Jarak, I; Machado, IF; Palmeira, CM; Rolo, AP; Teodoro, JS1
Bian, Z; Ge, K; Han, X; Huang, F; Jia, W; Li, M; Qu, C; Rajani, C; Wang, S; Wei, M; Xie, G; Yang, W; Zhang, Y; Zhao, A; Zhao, L; Zheng, X1
Andersen, H; Divanovic, S; Haslam, DB; Horrigan, O; Jose, S; Madan, R; Moreno-Fernandez, ME; Mukherjee, A; Setchell, KDR; Sharma, D; Zhang, W1
Attema, J; Caspers, MPM; de Ruiter, C; Kleemann, R; Menke, AL; Radhakrishnan, S; Salic, K; van den Hoek, AM; van Nieuwkoop, A; Verschuren, L; Worms, N1
Chan, HL; Chan, WK; Chawla, Y; Chitturi, S; Dan, YY; Duseja, A; Fan, J; Farrell, G; Goh, KL; Hamaguchi, M; Hashimoto, E; Kim, SU; Lesmana, LA; Lin, YC; Liu, CJ; Ni, YH; Sollano, J; Wong, GL; Wong, SK; Wong, VW1
Adorini, L; D'Agati, V; Dobrinskikh, E; Dvornikov, A; Field, A; Garcia, G; Gonzalez, FJ; Gratton, E; Henriksen, K; Herman-Edelstein, M; Hill, A; Jiang, T; Kopp, JB; Krausz, KW; Levi, J; Levi, M; Lucia, S; Luo, Y; Myakala, K; Orlicky, D; Peng, Y; Pruzanski, M; Qiu, L; Ranjit, S; Rosenberg, AZ; Wang, D; Wang, XX; Xie, C1
Feigh, M; Gillum, MP; Hansen, HH; Jelsing, J; Kristiansen, MN; Rigbolt, KT; Tølbøl, KS; Veidal, SS; Vrang, N1
Asakawa, M; Goto, T; Itoh, M; Kai, T; Kanai, S; Ogawa, Y; Sakai, T; Shirakawa, I; Suganami, T; Yoneyama, T1
Kumar, RB; Mathews, SE; Shukla, AP1
Bardova, K; Duarte, FV; Flachs, P; Gomes, AP; Janovska, P; Kopecký, J; Palmeira, CM; Rolo, AP; Teodoro, JS; Varela, AT; Zouhar, P1
Cortez-Pinto, H; Machado, MV1
Drews, G; Düfer, M; Kähny, V; Krippeit-Drews, P; Peter, A; Schittenhelm, B; Wagner, R1
Bao, Y; Chen, T; Jia, W; Ni, Y; Su, M; Tu, Y; Wei, L; Xie, G; Yu, H; Zhang, L; Zhang, P; Zhao, A1
Gai, Z; Gui, T; Hiller, C; Kullak-Ublick, GA1
Carvalho, RA; Jarak, I; Palmeira, CM; Rolo, AP; Teodoro, JS1
Barn, V; Farrell, GC; Geoffrey Haigh, W; Haczeyni, F; Ioannou, GN; Leclercq, IA; Mridha, AR; Poekes, L; Teoh, NC; Wang, H; Yeh, MM1
Cipriani, S; Fiorucci, S; Mencarelli, A; Palladino, G1
Fonseca, VA; Staels, B1
Bloks, VW; Brufau, G; Burgerhof, HG; Kuipers, F; Murphy, EJ; Romijn, HA; Scheltema, RA; Smelt, GH; Stellaard, F1
Baldelli, F; Cipriani, S; D'Amore, C; Distrutti, E; Fiorucci, S; Mencarelli, A; Palladino, G; Renga, B1
Sali, A1
Hall, JC; Iannos, J; Roberts, HG; Watts, JM; Whiting, MJ1
Grundy, SM1
Greenfield, MR; Jain, R; Quarfordt, SH1
Aufses, AH; Miller, SR; Panveliwalla, D; Papatestas, AE; Pertsemlidis, D1
Danzinger, RG; Kurtas, TK; Torchia, MG1
Carey, WD; Tangedahl, TN1
Andersen, B; Bruusgaard, A; Sørensen, TI1
Dioguardi, ML; Festorazzi, S; Podda, M; Zuin, M1
Leijd, B2
Dowling, RH; Maton, PN; Murphy, GM1
Jaffe, PE1
Méndez-Sánchez, N; Sánchez, JM; Uribe, M; Vargas-Vorockova, F1
Stremmel, W1
Tangedahl, T1
Crouse, JR; Grundy, SM; Mok, HY; von Bergmann, K1
Dowling, RH; Iser, JH; Maton, PN; Murphy, GM1
Stein, TA; Wise, L1
Bruusgaard, A; Justesen, T; Krag, E; Sörensen, TI1
Battezzati, PM; Bertolini, E; Crosignani, A; Grandinetti, G; Petroni, ML; Podda, M; Zuin, M1
Aldini, R; Bazzoli, F; Festi, D; Grigolo, B; Mazzella, G; Roda, A; Roda, E; Ronchi, M; Simoni, P; Villanova, N1
Dickerman, JL1
Dowling, RH; Murphy, GM; Qureshi, Y; Reuben, A1
Dowling, RH; Maton, PN; Murphy, GM; Reuben, A1
Einarsson, K; Hellström, K; Kallner, M1
Banwell, JG; Lockwood, DH; Nair, PP; Sherr, HP; White, JJ1
Greenfield, MF; Quarfordt, SH1

Reviews

7 review(s) available for chenodeoxycholic acid and Obesity

ArticleYear
The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.
    Journal of medicinal chemistry, 2020, 05-28, Volume: 63, Issue:10

    Topics: Animals; Anticholesteremic Agents; Drug Delivery Systems; Drug Development; Humans; Hypoglycemic Agents; Lipid Metabolism; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Obesity; PPAR gamma; Protein Structure, Tertiary

2020
The Asia-Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017-Part 2: Management and special groups.
    Journal of gastroenterology and hepatology, 2018, Volume: 33, Issue:1

    Topics: Adolescent; Asia; Bariatric Surgery; Carcinoma, Hepatocellular; Chenodeoxycholic Acid; Child; Diet; Exercise; Fatty Acids, Omega-3; Gastroenterology; Humans; Liver Neoplasms; Liver Transplantation; Non-alcoholic Fatty Liver Disease; Obesity; Pacific Islands; Practice Guidelines as Topic; Risk; Systematic Reviews as Topic; Thiazolidinediones; Vitamin E

2018
Nonalcoholic steatohepatitis, obesity, and cardiac dysfunction.
    Current opinion in endocrinology, diabetes, and obesity, 2018, Volume: 25, Issue:5

    Topics: Bariatric Surgery; Chenodeoxycholic Acid; Diet; Exercise; Heart Diseases; Humans; Life Style; Non-alcoholic Fatty Liver Disease; Obesity; Pioglitazone; Vitamin E

2018
Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration.
    Diabetes care, 2009, Volume: 32 Suppl 2

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol, HDL; Cholesterol, LDL; Cholic Acid; Diabetes Mellitus; Digestion; Homeostasis; Humans; Intestinal Absorption; Intestines; Liver; Obesity

2009
Medical therapy for gallstones. 1. Rationale and indications.
    Postgraduate medicine, 1982, Volume: 71, Issue:5

    Topics: Abnormalities, Drug-Induced; Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Cholelithiasis; Diabetes Complications; Female; Humans; Obesity; Phosphatidylcholines; Pregnancy; Prenatal Exposure Delayed Effects; Ursodeoxycholic Acid

1982
Gallstones. Who are good candidates for nonsurgical treatment?
    Postgraduate medicine, 1993, Nov-01, Volume: 94, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Chenodeoxycholic Acid; Cholecystitis; Cholecystostomy; Cholelithiasis; Chronic Disease; Ethers; Female; Humans; Instillation, Drug; Lithotripsy; Male; Methyl Ethers; Obesity; Recurrence; Risk Factors; Sex Factors; Solvents; Ursodeoxycholic Acid

1993
Dissolution of gallstones--when and how?
    The Surgical clinics of North America, 1979, Volume: 59, Issue:5

    Topics: Bile; Chenodeoxycholic Acid; Cholecystography; Cholelithiasis; Drug Administration Schedule; Female; Humans; Liver Diseases; Obesity; Pregnancy; Ursodeoxycholic Acid

1979

Trials

5 trial(s) available for chenodeoxycholic acid and Obesity

ArticleYear
Low-dose chenodeoxycholic acid for gallstone dissolution: a randomized trial in poor operative risk patients.
    Digestive diseases and sciences, 1980, Volume: 25, Issue:10

    Topics: Aged; Chenodeoxycholic Acid; Cholelithiasis; Clinical Trials as Topic; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Male; Middle Aged; Obesity; Placebos; Research Design; Solubility; Time Factors

1980
Bile acid malabsorption after jejunoileal bypass is less compensated for with a 1:3 than with a 3:1 jejunoileal ratio.
    Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Humans; Ileum; Intestinal Absorption; Jejunum; Kinetics; Methods; Obesity

1982
Bilary lipid metabolism in obesity. Effects of bile acid feeding before and during weight reduction.
    Gastroenterology, 1979, Volume: 76, Issue:3

    Topics: Adult; Bile; Bile Acids and Salts; Body Weight; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Deoxycholic Acid; Diet, Reducing; Humans; Lipid Metabolism; Male; Middle Aged; Obesity; Triglycerides

1979
Comparison of effects of chenodeoxycholic and ursodeoxycholic acid and their combination on biliary lipids in obese patients with gallstones.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:3

    Topics: Bile Acids and Salts; Biliary Tract; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Obesity; Patient Compliance; Patient Dropouts; Phospholipids; Ursodeoxycholic Acid

1991
Comparative evaluation of chenodeoxycholic and ursodeoxycholic acids in obese patients. Effects on biliary lipid metabolism during weight maintenance and weight reduction.
    Gastroenterology, 1991, Volume: 101, Issue:2

    Topics: Adolescent; Adult; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Drug Evaluation; Female; Humans; Male; Middle Aged; Obesity; Phospholipids; Ursodeoxycholic Acid; Weight Loss

1991

Other Studies

38 other study(ies) available for chenodeoxycholic acid and Obesity

ArticleYear
Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.
    Journal of medicinal chemistry, 2009, Dec-24, Volume: 52, Issue:24

    Topics: Animals; Chlorocebus aethiops; CHO Cells; Cholic Acids; COS Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Humans; Obesity; Rats; Receptors, G-Protein-Coupled; Stereoisomerism

2009
Chenodeoxycholic Acid Has Non-Thermogenic, Mitodynamic Anti-Obesity Effects in an In Vitro CRISPR/Cas9 Model of Bile Acid Receptor TGR5 Knockdown.
    International journal of molecular sciences, 2021, Oct-29, Volume: 22, Issue:21

    Topics: 3T3-L1 Cells; Animals; Anti-Obesity Agents; Chenodeoxycholic Acid; CRISPR-Cas Systems; Gene Knockdown Techniques; Mice; Mitochondria; Obesity; Receptors, G-Protein-Coupled; Thermogenesis

2021
A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility.
    EBioMedicine, 2020, Volume: 55

    Topics: Adipose Tissue, Brown; Animals; Body Mass Index; Chenodeoxycholic Acid; Cholestenones; Clostridiales; Cohort Studies; Diet, High-Fat; Disease Models, Animal; Disease Susceptibility; Gastrointestinal Microbiome; Gene Expression Regulation; Glucagon-Like Peptide 1; Humans; Ileum; Lithocholic Acid; Male; Metagenomics; Mice; Mice, Inbred C57BL; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Uncoupling Protein 1; Ursodeoxycholic Acid

2020
Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice.
    Mucosal immunology, 2021, Volume: 14, Issue:2

    Topics: Animals; Anticholesteremic Agents; Chenodeoxycholic Acid; Clostridioides difficile; Clostridium Infections; Diet, High-Fat; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; RNA-Binding Proteins

2021
A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology.
    Cells, 2020, 09-01, Volume: 9, Issue:9

    Topics: Animals; Atherosclerosis; Chenodeoxycholic Acid; Diet, High-Fat; Disease Models, Animal; Fast Foods; Hyperinsulinism; Hyperlipidemias; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, LDL; Transcriptome; Treatment Outcome

2020
FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:1

    Topics: Albuminuria; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Endoplasmic Reticulum Stress; Fibrosis; Glomerular Mesangium; Humans; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitochondria; Obesity; Oxidative Stress; Podocytes; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Triglycerides

2018
Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis.
    World journal of gastroenterology, 2018, Jan-14, Volume: 24, Issue:2

    Topics: Animals; Biopsy; Chalcones; Chenodeoxycholic Acid; Collagen Type I; Collagen Type I, alpha 1 Chain; Diet, High-Fat; Disease Models, Animal; Galectin 3; Lipid Metabolism; Liraglutide; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Propionates; Time Factors; Weight Gain

2018
Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis.
    Scientific reports, 2018, 05-25, Volume: 8, Issue:1

    Topics: Animals; Body Weight; Cell Death; Chenodeoxycholic Acid; Cytoprotection; Disease Models, Animal; Disease Progression; Gene Knockout Techniques; Hepatocytes; Insulin Resistance; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Receptor, Melanocortin, Type 4; Tumor Suppressor Protein p53

2018
Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice.
    International journal of obesity (2005), 2014, Volume: 38, Issue:8

    Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blotting, Western; Chenodeoxycholic Acid; Diet, High-Fat; Energy Metabolism; Glucose Intolerance; Ion Channels; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondrial Proteins; Obesity; Oxidative Stress; Real-Time Polymerase Chain Reaction; Signal Transduction; Thermogenesis; Uncoupling Protein 1

2014
Nuclear receptors: how do they position in non-alcoholic fatty liver disease treatment?
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:9

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Energy Metabolism; Humans; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Cytoplasmic and Nuclear

2014
Role of FXR in β-cells of lean and obese mice.
    Endocrinology, 2015, Volume: 156, Issue:4

    Topics: Animals; Chenodeoxycholic Acid; Female; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Isoxazoles; Male; Mice; Mice, Knockout; Mice, Obese; Obesity; Receptors, Cytoplasmic and Nuclear; Taurochenodeoxycholic Acid

2015
Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:11

    Topics: Adult; Anastomosis, Roux-en-Y; Asian People; Bile Acids and Salts; Biomarkers; Body Mass Index; Chenodeoxycholic Acid; China; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Obesity; Overweight; Predictive Value of Tests; Prognosis; Retrospective Studies; Treatment Outcome

2015
Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice.
    The Journal of biological chemistry, 2016, Jan-29, Volume: 291, Issue:5

    Topics: Aldehydes; Animals; Bile Acids and Salts; CCAAT-Enhancer-Binding Proteins; Chenodeoxycholic Acid; Diet, High-Fat; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Fatty Acids, Nonesterified; Female; Glutathione; Heat-Shock Proteins; Humans; Kidney; Kidney Diseases; Kidney Tubules; Lipid Metabolism; Lipid Peroxidation; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Middle Aged; Nephrectomy; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear

2016
The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity.
    NMR in biomedicine, 2016, Volume: 29, Issue:10

    Topics: 3T3-L1 Cells; Adipose Tissue, White; Animals; Bile Acids and Salts; Carbon-13 Magnetic Resonance Spectroscopy; Cell Survival; Chenodeoxycholic Acid; Dose-Response Relationship, Drug; Glucose; Metabolic Networks and Pathways; Mice; Obesity

2016
Obeticholic acid improves adipose morphometry and inflammation and reduces steatosis in dietary but not metabolic obesity in mice.
    Obesity (Silver Spring, Md.), 2017, Volume: 25, Issue:1

    Topics: Adiposity; Animals; Chenodeoxycholic Acid; Diet, Atherogenic; Disease Models, Animal; Fatty Liver; Female; Inflammation; Liver; Mice; Mice, Inbred NOD; Mice, Obese; Obesity; Weight Gain

2017
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats.
    Journal of lipid research, 2010, Volume: 51, Issue:4

    Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Male; Muscle, Skeletal; Obesity; Phosphorylation; Random Allocation; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors

2010
Two time-point assessment of bile acid kinetics in humans using stable isotopes.
    Isotopes in environmental and health studies, 2010, Volume: 46, Issue:3

    Topics: Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholic Acid; Deoxycholic Acid; Deuterium; Diabetes Mellitus, Type 2; Female; Humans; Hypertriglyceridemia; Isotope Labeling; Kinetics; Male; Obesity; Radioisotope Dilution Technique; Reference Values; Time Factors

2010
FXR activation improves myocardial fatty acid metabolism in a rodent model of obesity-driven cardiotoxicity.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2013, Volume: 23, Issue:2

    Topics: Acyl-CoA Oxidase; Animals; Apoptosis; Bile Acids and Salts; Blood Glucose; Cardiovascular Diseases; Chenodeoxycholic Acid; Dyslipidemias; Fibrosis; Hyperinsulinism; Hyperlipidemias; Insulin Resistance; Isoxazoles; Lipid Metabolism; Liver; Myocardium; Obesity; PPAR alpha; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Risk Factors; RNA, Messenger; Triglycerides

2013
Gallbladder disease. New trends in diagnosis and management.
    Australian family physician, 1984, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Biliary Tract; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Diet; Female; Humans; Liver; Male; Middle Aged; Obesity; Physical Therapy Modalities; Radionuclide Imaging; Ultrasonic Therapy; Ultrasonography; Ursodeoxycholic Acid

1984
The cholesterol saturation of bile and its reduction by chenodeoxycholic acid in massively obese patients.
    International journal of obesity, 1984, Volume: 8, Issue:6

    Topics: Adult; Aged; Bile Acids and Salts; Body Weight; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Female; Humans; Lipid Metabolism; Lipids; Male; Middle Aged; Obesity; Risk

1984
Mechanism of cholesterol gallstones formation.
    Seminars in liver disease, 1983, Volume: 3, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Chylomicrons; Circadian Rhythm; Clofibrate; Diet; Dogs; Female; Gastrointestinal Diseases; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Liver; Male; Obesity; Rats; Recurrence; Sex Factors; Solubility

1983
The influence of chenodeoxycholic acid on cholesterol and bile acid turnover in humans with cholelithiasis.
    Lipids, 1983, Volume: 18, Issue:2

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Double-Blind Method; Female; Humans; Hyperlipoproteinemias; Male; Middle Aged; Obesity; Time Factors

1983
Fecal steroid excretion and degradation and breast cancer stage.
    The Journal of surgical research, 1983, Volume: 34, Issue:6

    Topics: Breast Neoplasms; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Feces; Female; Humans; Neoplasm Staging; Obesity

1983
Successful treatment of gallstones with bile acids in obese adolescents.
    Archives of disease in childhood, 1982, Volume: 57, Issue:12

    Topics: Adolescent; Bile Acids and Salts; Chenodeoxycholic Acid; Child; Cholelithiasis; Female; Humans; Male; Obesity; Ursodeoxycholic Acid

1982
The effect of weight reduction on biliary lipid metabolism in patients with hyperlipoproteinemia type IV.
    Metabolism: clinical and experimental, 1981, Volume: 30, Issue:12

    Topics: Adult; Bile; Body Weight; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Diet, Reducing; Female; Humans; Hyperlipoproteinemia Type IV; Lipids; Male; Middle Aged; Obesity; Steroids

1981
Cholesterol and bile acid metabolism in obesity.
    Clinical science (London, England : 1979), 1980, Volume: 59, Issue:3

    Topics: Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Female; Humans; Male; Middle Aged; Obesity; Steroids

1980
Lack of response to chenodeoxycholic acid in obese and non-obese patients. Role of cholesterol synthesis and possible response to ursodeoxycholic acid.
    Gut, 1980, Volume: 21, Issue:12

    Topics: Adult; Aged; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Deoxycholic Acid; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Middle Aged; Obesity; Solubility; Ursodeoxycholic Acid

1980
Similar fragmentation and dissolution after extracorporeal shock wave lithotripsy in eutrophic and overweight patients with gallstones.
    The Netherlands journal of medicine, 1996, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Body Mass Index; Chenodeoxycholic Acid; Cholelithiasis; Female; Follow-Up Studies; Gallbladder Emptying; Humans; Lithotripsy; Male; Middle Aged; Obesity; Risk Factors; Treatment Outcome; Ursodeoxycholic Acid

1996
[Factors predisposing for cholelithiasis].
    MMW, Munchener medizinische Wochenschrift, 1979, Dec-21, Volume: 121, Issue:51-52

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Dietary Fiber; Energy Intake; Fatty Acids, Unsaturated; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Male; Mixed Function Oxygenases; Obesity; Risk

1979
Resistance to chenodeoxycholic acid (CDCA) treatment in obese patients with gall stones.
    British medical journal, 1978, Jun-10, Volume: 1, Issue:6126

    Topics: Adult; Bile; Body Weight; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Drug Administration Schedule; Drug Resistance; Female; Humans; Male; Middle Aged; Obesity

1978
Bile salt metabolism following jejunoileal bypass for morbid obesity.
    Annals of surgery, 1977, Volume: 185, Issue:1

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholecystokinin; Cholic Acids; Female; Humans; Ileum; Jejunum; Kinetics; Middle Aged; Obesity; Radioactive Tracers

1977
Bile acid metabolism after jejunoileal bypass operation for obesity.
    Scandinavian journal of gastroenterology, 1976, Volume: 11, Issue:8

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Duodenum; Glycine; Humans; Intestine, Small; Obesity; Taurine

1976
Gallstone formation associated with weight reduction.
    The Journal of the American Osteopathic Association, 1990, Volume: 90, Issue:5

    Topics: Adult; Chenodeoxycholic Acid; Cholelithiasis; Diet, Reducing; Female; Humans; Obesity; Radiography

1990
Effect of obesity and weight reduction on biliary cholesterol saturation and the response to chenodeoxycholic acid.
    European journal of clinical investigation, 1986, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Bile; Body Weight; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Female; Humans; Male; Middle Aged; Obesity

1986
Bile lipid secretion in obese and non-obese individuals with and without gallstones.
    Clinical science (London, England : 1979), 1985, Volume: 69, Issue:1

    Topics: Adult; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Fasting; Female; Humans; Lipid Metabolism; Lipids; Male; Middle Aged; Obesity; Secretory Rate

1985
Bile acid kinetics in relation to sex, serum lipids, body weights, and gallbladder disease in patients with various types of hyperlipoproteinemia;.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:6

    Topics: Adult; Aged; Bile Acids and Salts; Blood Protein Disorders; Body Weight; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholic Acids; Electrophoresis; Female; Gallbladder Diseases; Glucose; Humans; Hypercholesterolemia; Hyperlipidemias; Kinetics; Lipids; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Obesity; Sex Factors; Triglycerides; Tritium

1974
Bile acid metabolism and hepatic disease following small bowel bypass for obesity.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:12

    Topics: Adult; Bile; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Fatty Liver; Female; Glycine; Humans; Ileum; Jejunum; Lithocholic Acid; Liver; Liver Cirrhosis; Liver Diseases; Male; Obesity; Postoperative Complications; Protein Deficiency; Sulfuric Acids; Taurine

1974
Estimation of cholesterol and bile acid turnover in man by kinetic analysis.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:8

    Topics: Adult; Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholesterol; Cholestyramine Resin; Cholic Acids; Deoxycholic Acid; Dietary Fats; Fats, Unsaturated; Female; Humans; Injections, Intravenous; Intubation, Gastrointestinal; Kinetics; Liver Cirrhosis; Male; Middle Aged; Obesity; Time Factors; Triglycerides; Tritium

1973