chenodeoxycholic acid has been researched along with Innate Inflammatory Response in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 18 (60.00) | 24.3611 |
| 2020's | 7 (23.33) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Heitel, P; Kalinowsky, L; Merk, D; Proschak, E | 1 |
| Ge, X; Guo, S; Jiao, T; Li, C; Liu, Y; Nan, F; Wang, K; Wang, Y; Xie, C; Xie, X; Yin, J; Zhang, C | 1 |
| Bennett, AL; Dawson, PA; Donepudi, AC; Karpen, SJ; Klindt, C; Malla, SR; Moustafa, T; Pachura, KJ; Truong, JK; Zaufel, A | 1 |
| Chen, W; Ding, M; Guo, Y; Huang, M; Ji, L; Jin, X; Lin, Y; Liu, Z; Lu, L; Shen, Q; Wang, Y; Yan, W; Yao, J; Yu, S; Zheng, Y | 1 |
| Adorini, L; Brescia, P; Galbiati, M; Invernizzi, P; Mileti, E; Mouries, J; Penna, G; Rescigno, M; Silvestri, A; Sorribas, M; Spadoni, I; Wiest, R | 1 |
| Feng, W; Hao, Z; Liu, Y; Ren, L; Song, Q; Zhang, L | 1 |
| Ai, Q; Chen, Q; Du, J; Li, Y; Mai, K; Xiang, X; Xu, W | 1 |
| Feng, R; Liu, C; Ma, LJ; Su, H; Wan, JB; Wang, M; Yang, R; Yang, Y | 1 |
| Dou, B; Fan, S; Huang, C; Huang, J; Huang, L; Li, J; Liu, C; Zheng, P; Zhou, Z | 1 |
| Chen, J; Gu, X; Luo, H; Su, C; Tang, J; Xiao, L; Xiong, F; Zha, L; Zhao, Y; Zheng, Z | 1 |
| Afonso, MB; Borralho, PM; Carvalho, CC; Castro, RE; Cortez-Pinto, H; Duarte, A; Machado, MV; Rodrigues, CM; Rodrigues, PM; Simão, AL; Trindade, A | 1 |
| Adorini, L; Comeglio, P; Maggi, M; Morelli, A; Vignozzi, L | 1 |
| Ai, Q; Du, J; Ji, R; Li, Y; Mai, K; Xiang, X; Xu, H | 1 |
| Cui, Y; Li, R; Ren, Y; Wang, C; Xiong, X; Zhang, Y | 1 |
| Chen, YH; Fei, J; Fu, L; Hu, B; Li, JB; Xu, DX; Zhao, H | 1 |
| Chen, X; Ding, W; Fan, YY; Fu, L; Xu, DX; Zhang, C | 1 |
| Adorini, L; Cellai, I; Comeglio, P; Filippi, S; Maggi, M; Maneschi, E; Marini, M; Morelli, A; Persani, L; Rastrelli, G; Sarchielli, E; Vannelli, GB; Vignozzi, L | 1 |
| James, J; Roy, D; Shihabudeen, MS; Thirumurugan, K | 1 |
| Albillos, A; Álvarez-Mon, M; Borrero, MJ; Del Campo, R; Díaz, D; García-Bermejo, L; Lario, M; Lledó, L; Muñoz, L; Pastor, Ó; Rodríguez-Serrano, M; Sánchez-Díaz, AM; Úbeda, M | 1 |
| Adorini, L; Cellai, I; Comeglio, P; Filippi, S; Maggi, M; Maneschi, E; Morelli, A; Sarchielli, E; Vannelli, GB; Vignozzi, L | 1 |
| Farre, R; Govaere, O; Klein, S; Laleman, W; Mannaerts, I; Mazzone, M; Nevens, F; Schierwagen, R; Trebicka, J; van Grunsven, LA; Vander Elst, I; Verbeke, L; Wenes, M; Windmolders, P | 1 |
| Barn, V; Farrell, GC; Geoffrey Haigh, W; Haczeyni, F; Ioannou, GN; Leclercq, IA; Mridha, AR; Poekes, L; Teoh, NC; Wang, H; Yeh, MM | 1 |
| Adorini, L; Cellai, I; Comeglio, P; Corcetto, F; Corno, C; Filippi, S; Maggi, M; Maneschi, E; Morelli, A; Pini, A; Sarchielli, E; Vannelli, GB; Vignozzi, L | 1 |
| Fujimoto, Y; Iida, T; Yasukawa, K | 1 |
| Gao, M; Gong, W; He, F; Huang, G; Pan, Z; Xu, Z; Zeng, Y; Zhang, Y; Zhao, Y; Zhou, P | 1 |
| Bishop-Bailey, D; Li, YT; Swales, KE; Thomas, GJ; Warner, TD | 1 |
| Ajani, J; Buttar, NS; Chen, CT; Chou, CK; Guha, S; Hsu, JM; Huang, P; Hung, MC; Izzo, JG; Kuo, HP; Lee, DF; Sun, HL; Wang, KK; Wei, Y; Wu, TT; Yen, CJ | 1 |
| Al-Dhahir, HA; Zeitlin, IJ | 1 |
| Czaja, MJ; Dannenberg, AJ; de Lédinghen, V; Liu, H; Lo, CR; Subbaramaiah, K; Zhang, F | 1 |
2 review(s) available for chenodeoxycholic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
Topics: Animals; Cyclooxygenase Inhibitors; Drug Discovery; Fatty Acids; Humans; Inflammation; Models, Molecular | 2017 |
Beneficial effects of bile acid receptor agonists in pulmonary disease models.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Drug Design; Humans; Inflammation; Lung Diseases; Molecular Targeted Therapy; Pulmonary Fibrosis; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled | 2017 |
1 trial(s) available for chenodeoxycholic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Activation of the Farnesoid X Receptor (FXR) Suppresses Linoleic Acid-Induced Inflammation in the Large Yellow Croaker (Larimichthys crocea).
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cell Line; Chenodeoxycholic Acid; Diet; Fish Oils; Gene Expression Regulation; Hepatocytes; Inflammation; Kidney; Linoleic Acid; Perciformes; Receptors, Cytoplasmic and Nuclear; Soybean Oil | 2020 |
27 other study(ies) available for chenodeoxycholic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis.
Topics: Animals; Betulinic Acid; Bile Acids and Salts; Ceramides; Fibrosis; Glucose; Inflammasomes; Inflammation; Islet Amyloid Polypeptide; Liver; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Pentacyclic Triterpenes; Receptors, Cytoplasmic and Nuclear | 2022 |
Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury.
Topics: Animals; Bile Acids and Salts; Carrier Proteins; Chenodeoxycholic Acid; Cholestasis; Cyclic N-Oxides; Female; Humans; Inflammation; Liver; Male; Membrane Glycoproteins; Mice; Tropanes | 2022 |
Bile acids promote the development of HCC by activating inflammasome.
Topics: Animals; Bile Acids and Salts; Carcinoma, Hepatocellular; Cells, Cultured; Chenodeoxycholic Acid; Inflammasomes; Inflammation; Liver Neoplasms; Mice; Molecular Docking Simulation; Reactive Oxygen Species | 2023 |
Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development.
Topics: Animals; Bacterial Translocation; Capillary Permeability; Chenodeoxycholic Acid; Diet, High-Fat; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Insulin Resistance; Intestinal Mucosa; Liver; Mice; Non-alcoholic Fatty Liver Disease; Protective Agents | 2019 |
Probiotic Lactobacillus rhamnosus GG prevents progesterone metabolite epiallaopregnanolone sulfate-induced hepatic bile acid accumulation and liver injury.
Topics: Angiogenic Proteins; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Liver; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Probiotics; RNA-Binding Proteins; Signal Transduction; Ursodeoxycholic Acid | 2019 |
Oxidation of fish oil exacerbates alcoholic liver disease by enhancing intestinal dysbiosis in mice.
Topics: Animals; Anti-Bacterial Agents; Chenodeoxycholic Acid; Dysbiosis; Ethanol; Fish Oils; Gastrointestinal Microbiome; Inflammation; Intestines; Liver; Liver Diseases, Alcoholic; Mice; Oxidation-Reduction; RNA, Ribosomal, 16S | 2020 |
Isotschimgine alleviates nonalcoholic steatohepatitis and fibrosis via FXR agonism in mice.
Topics: Animals; Carbon Tetrachloride; Chenodeoxycholic Acid; Diet; Inflammation; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phenyl Ethers | 2021 |
Soyasaponin A
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Choline Deficiency; Colon; Diet; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Saponins | 2021 |
miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice.
Topics: Animals; Apoptosis; Chenodeoxycholic Acid; Disease Models, Animal; Fast Foods; Inflammation; Liver Cirrhosis; Male; Mice; Mice, Knockout; MicroRNAs; Non-alcoholic Fatty Liver Disease; PPAR alpha; Receptors, Cytoplasmic and Nuclear | 2017 |
Molecular cloning and characterization of farnesoid X receptor from large yellow croaker (Larimichthys crocea) and the effect of dietary CDCA on the expression of inflammatory genes in intestine and spleen.
Topics: Animals; Chenodeoxycholic Acid; Cloning, Molecular; Fish Proteins; Gene Expression Regulation; Inflammation; Intestinal Mucosa; Organ Specificity; Perciformes; Receptors, Cytoplasmic and Nuclear; Spleen | 2018 |
Obeticholic acid protects mice against lipopolysaccharide-induced liver injury and inflammation.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Hepatocytes; Inflammation; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Protective Agents; Receptors, Cytoplasmic and Nuclear | 2017 |
Obeticholic acid alleviate lipopolysaccharide-induced acute lung injury via its anti-inflammatory effects in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Chenodeoxycholic Acid; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Obeticholic acid differentially regulates hepatic injury and inflammation at different stages of D-galactosamine/lipopolysaccharide-evoked acute liver failure.
Topics: Animals; Cell Death; Chenodeoxycholic Acid; Female; Galactosamine; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; NF-kappa B | 2019 |
Metabolic syndrome induces inflammation and impairs gonadotropin-releasing hormone neurons in the preoptic area of the hypothalamus in rabbits.
Topics: Animals; Antibodies, Monoclonal; Biomarkers; Chenodeoxycholic Acid; Diet, High-Fat; Gene Expression Regulation; Glucose Transporter Type 4; Gonadotropin-Releasing Hormone; Immunohistochemistry; Inflammation; Infliximab; Male; Metabolic Syndrome; Neurons; Preoptic Area; Rabbits; Receptors, G-Protein-Coupled; RNA, Messenger | 2014 |
Chenodeoxycholic acid, an endogenous FXR ligand alters adipokines and reverses insulin resistance.
Topics: 3T3-L1 Cells; Adipokines; Adipose Tissue; Animals; Chenodeoxycholic Acid; Gene Expression Regulation; Inflammation; Inflammation Mediators; Insulin Resistance; Male; Mice; Palmitic Acid; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear | 2015 |
Obeticholic acid reduces bacterial translocation and inhibits intestinal inflammation in cirrhotic rats.
Topics: Animals; Chenodeoxycholic Acid; Cytokines; Inflammation; Intestinal Mucosa; Intestines; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley | 2016 |
Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension.
Topics: Animals; Chenodeoxycholic Acid; Exercise Test; Gene Expression Profiling; Gene Expression Regulation; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Lung; Lung Injury; Male; Monocrotaline; Organ Size; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger | 2017 |
FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis.
Topics: Animals; Apoptosis; Biomarkers; Cell Cycle; Cell Line; Cell Proliferation; Chenodeoxycholic Acid; Cytokines; Disease Models, Animal; Endothelial Cells; Hemodynamics; Hepatic Stellate Cells; Hepatocytes; Humans; Inflammation; Inflammation Mediators; Kupffer Cells; Lipopolysaccharides; Liver; Liver Cirrhosis; Male; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Portal Pressure; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thioacetamide; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Resistance | 2016 |
Obeticholic acid improves adipose morphometry and inflammation and reduces steatosis in dietary but not metabolic obesity in mice.
Topics: Adiposity; Animals; Chenodeoxycholic Acid; Diet, Atherogenic; Disease Models, Animal; Fatty Liver; Female; Inflammation; Liver; Mice; Mice, Inbred NOD; Mice, Obese; Obesity; Weight Gain | 2017 |
Anti-fibrotic effects of chronic treatment with the selective FXR agonist obeticholic acid in the bleomycin-induced rat model of pulmonary fibrosis.
Topics: Airway Remodeling; Animals; Bleomycin; Chenodeoxycholic Acid; Collagen; Disease Models, Animal; Fibrosis; Gene Expression Profiling; Immunohistochemistry; Inflammation; Lung; Male; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Ventricular Remodeling | 2017 |
Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Bile Acids and Salts; Carcinogens; Chenodeoxycholic Acid; Disease Models, Animal; Edema; Female; Indomethacin; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2009 |
FXR ligands protect against hepatocellular inflammation via SOCS3 induction.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Chenodeoxycholic Acid; Hep G2 Cells; Humans; Inflammation; Ligands; Lipopolysaccharides; Liver Neoplasms; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins | 2012 |
Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration.
Topics: Animals; Anti-Inflammatory Agents; Becaplermin; Cell Line; Cell Movement; Cell Survival; Cells, Cultured; Chenodeoxycholic Acid; Cyclooxygenase 2; DNA-Binding Proteins; Dose-Response Relationship, Drug; Genes, Reporter; Humans; Inflammation; Interleukin-1beta; Isoxazoles; Ligands; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide Synthase Type II; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Receptors, Cytoplasmic and Nuclear; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transcription Factors; Transcription, Genetic; Transfection | 2007 |
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
Topics: Adenocarcinoma; Barrett Esophagus; Bile Acids and Salts; Cell Division; Chenodeoxycholic Acid; Esophageal Neoplasms; Gastroesophageal Reflux; Gene Expression Regulation, Neoplastic; Humans; Inflammation; NF-kappa B; Nitriles; Protein Kinases; RNA, Small Interfering; Sirolimus; Sulfones; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins; Ursodeoxycholic Acid | 2008 |
Bile salts activate glandular kallikrein-like activity in rat colon.
Topics: Amidohydrolases; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Colon; Enzyme Activation; Inflammation; Intestinal Mucosa; Kallikreins; Male; Perfusion; Rats; Rats, Inbred Strains | 1983 |
Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes.
Topics: Animals; Blotting, Western; Carcinogens; CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Chenodeoxycholic Acid; Cyclooxygenase 2; Cytochrome P-450 CYP2E1; Electrophoretic Mobility Shift Assay; Enzyme Induction; Hepatocytes; Inflammation; Isoenzymes; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 2002 |