Page last updated: 2024-08-21

chenodeoxycholic acid and Fatty Liver

chenodeoxycholic acid has been researched along with Fatty Liver in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's9 (56.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Gai, Z; Krajnc, E; Kullak-Ublick, GA; Samodelov, SL; Visentin, M1
Adorini, L; Castelloe, E; Clopton, P; Dillon, P; Henry, RR; Kipnes, M; Marschall, HU; Morrow, L; Mudaliar, S; Pruzanski, M; Sanyal, AJ; Sciacca, CI; Shapiro, D1
Karpen, SJ1
Hayashi, Y; Ishii, A; Jia, X; Kaneko, R; Kato, M; Kitamori, K; Naito, H; Nakajima, T; Nomura, M; Suzuki, Y; Yamori, Y; Yetti, H; Zaitsu, K1
Adorini, L; Cellai, I; Comeglio, P; Filippi, S; Galli, A; Maggi, M; Maneschi, E; Mannucci, E; Morelli, A; Rastrelli, G; Saad, F; Sarchielli, E; Vannelli, GB; Vignozzi, L1
Acco, A; Bastos-Pereira, AL; Chicorski, R; de Oliveira, LG; de Souza, CE; Dreifuss, AA; Fabossi, IA; Gremski, LH; Henneberg, R; LĂ­vero, FA; Oude Elferink, RP; Rabitto, IS; Stolf, AM; Telles, JE1
Jun, DW; Nguyen, MH; Oh, H; Saeed, WK1
Barn, V; Farrell, GC; Geoffrey Haigh, W; Haczeyni, F; Ioannou, GN; Leclercq, IA; Mridha, AR; Poekes, L; Teoh, NC; Wang, H; Yeh, MM1
Cipriani, S; Fiorucci, S; Mencarelli, A; Palladino, G1
Adorini, L; Pruzanski, M; Shapiro, D1
Aranha, MM; Camilo, ME; Cortez-Pinto, H; Costa, A; da Silva, IB; de Moura, MC; Rodrigues, CM1
Brunner, H; Grabner, G; Horak, W1
Bochet, S; Borel, GA1
Leuschner, U1
Banwell, JG; Lockwood, DH; Nair, PP; Sherr, HP; White, JJ1
Bergman, F; van der Linden, W1

Reviews

2 review(s) available for chenodeoxycholic acid and Fatty Liver

ArticleYear
Non-alcoholic fatty liver diseases: update on the challenge of diagnosis and treatment.
    Clinical and molecular hepatology, 2016, Volume: 22, Issue:3

    Topics: Biomarkers; Chenodeoxycholic Acid; Clinical Trials as Topic; Fatty Liver; Fibrosis; Humans; Liver; Magnetic Resonance Imaging; Non-alcoholic Fatty Liver Disease; Tomography, X-Ray Computed; Ultrasonography; Vitamin E

2016
Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis.
    Drug discovery today, 2012, Volume: 17, Issue:17-18

    Topics: Animals; Chenodeoxycholic Acid; Fatty Liver; Humans; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear

2012

Trials

1 trial(s) available for chenodeoxycholic acid and Fatty Liver

ArticleYear
Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease.
    Gastroenterology, 2013, Volume: 145, Issue:3

    Topics: Adult; Aged; Biomarkers; Chenodeoxycholic Acid; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Fatty Liver; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2013

Other Studies

13 other study(ies) available for chenodeoxycholic acid and Fatty Liver

ArticleYear
Obeticholic Acid Ameliorates Valproic Acid-Induced Hepatic Steatosis and Oxidative Stress.
    Molecular pharmacology, 2020, Volume: 97, Issue:5

    Topics: Animals; Antioxidants; Body Weight; Cell Line, Tumor; Chenodeoxycholic Acid; Cytochrome P-450 Enzyme System; Fatty Liver; Female; Lipid Metabolism; Liver; Liver Function Tests; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcriptome; Valproic Acid

2020
Do therapeutic bile acids hit the sweet spot of glucose metabolism in NAFLD?
    Gastroenterology, 2013, Volume: 145, Issue:3

    Topics: Chenodeoxycholic Acid; Diabetes Mellitus, Type 2; Fatty Liver; Female; Humans; Hypoglycemic Agents; Male; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear

2013
A possible role of chenodeoxycholic acid and glycine-conjugated bile acids in fibrotic steatohepatitis in a dietary rat model.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:7

    Topics: Animals; Biomarkers; Chenodeoxycholic Acid; Cholic Acid; Chromatography, Liquid; Deoxycholic Acid; Diet, High-Fat; Fatty Liver; Liver; Liver Cirrhosis; Male; Non-alcoholic Fatty Liver Disease; Random Allocation; Rats; Tandem Mass Spectrometry

2014
Nonalcoholic steatohepatitis as a novel player in metabolic syndrome-induced erectile dysfunction: an experimental study in the rabbit.
    Molecular and cellular endocrinology, 2014, Mar-25, Volume: 384, Issue:1-2

    Topics: Acetylcholine; Animals; Antibodies, Monoclonal; Chenodeoxycholic Acid; Diet, High-Fat; Dietary Fats; Erectile Dysfunction; Fatty Liver; Gene Expression; Humans; Imidazoles; Infliximab; Liver; Male; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Penis; Phosphodiesterase 5 Inhibitors; Piperazines; Rabbits; Receptors, Cytoplasmic and Nuclear; Sulfones; Testosterone; Triazines; Tumor Necrosis Factor-alpha; Vardenafil Dihydrochloride

2014
The FXR agonist 6ECDCA reduces hepatic steatosis and oxidative stress induced by ethanol and low-protein diet in mice.
    Chemico-biological interactions, 2014, Jun-25, Volume: 217

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Chenodeoxycholic Acid; Cholesterol; Ethanol; Fatty Liver; Gastrointestinal Agents; Glutathione Transferase; Histocytochemistry; Liver Diseases, Alcoholic; Male; Mice; Oxidative Stress; Receptors, Cytoplasmic and Nuclear; Superoxide Dismutase; Triglycerides

2014
Obeticholic acid improves adipose morphometry and inflammation and reduces steatosis in dietary but not metabolic obesity in mice.
    Obesity (Silver Spring, Md.), 2017, Volume: 25, Issue:1

    Topics: Adiposity; Animals; Chenodeoxycholic Acid; Diet, Atherogenic; Disease Models, Animal; Fatty Liver; Female; Inflammation; Liver; Mice; Mice, Inbred NOD; Mice, Obese; Obesity; Weight Gain

2017
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats.
    Journal of lipid research, 2010, Volume: 51, Issue:4

    Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Male; Muscle, Skeletal; Obesity; Phosphorylation; Random Allocation; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors

2010
Bile acid levels are increased in the liver of patients with steatohepatitis.
    European journal of gastroenterology & hepatology, 2008, Volume: 20, Issue:6

    Topics: Adult; Bile Acids and Salts; Biopsy; Chenodeoxycholic Acid; Cholic Acid; Chromatography, Gas; Deoxycholic Acid; Disease Progression; Fatty Liver; Fatty Liver, Alcoholic; Female; Humans; Liver; Male; Middle Aged; Severity of Illness Index

2008
[Adverse effects of chenodeoxycholic-acid therapy].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1976, Issue:9

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Fatty Liver; Humans

1976
[Clinical application of the radiolabeled bile salt tolerance test].
    Schweizerische medizinische Wochenschrift, 1978, Jul-29, Volume: 108, Issue:30

    Topics: Chenodeoxycholic Acid; Fatty Liver; Hepatitis, Viral, Human; Humans; Liver; Liver Cirrhosis; Radionuclide Imaging

1978
[Dissolution of cholesterol calculi using chenodeoxycholic acid].
    Deutsche medizinische Wochenschrift (1946), 1976, Jul-23, Volume: 101, Issue:30

    Topics: Alcoholism; Chenodeoxycholic Acid; Cholecystitis; Cholelithiasis; Cholestasis; Cholesterol; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis

1976
Bile acid metabolism and hepatic disease following small bowel bypass for obesity.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:12

    Topics: Adult; Bile; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Fatty Liver; Female; Glycine; Humans; Ileum; Jejunum; Lithocholic Acid; Liver; Liver Cirrhosis; Liver Diseases; Male; Obesity; Postoperative Complications; Protein Deficiency; Sulfuric Acids; Taurine

1974
Liver morphology and gallstone formation in hamsters and mice treated with chenodeoxycholic acid.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1973, Volume: 81, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cricetinae; Diet; Fatty Liver; Female; Liver; Male; Mice

1973