chenodeoxycholic acid and Disease Models, Animal

Topics: Animals; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Models, Animal; Drug Design; Fluorescent Antibody Technique, Indirect; Humans; Liver Cirrhosis, Biliary; Precision Medicine; Ursodeoxycholic Acid

Topics: Animals; Chenodeoxycholic Acid; Cholangitis, Sclerosing; Disease Models, Animal; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Treatment Outcome

Topics: Animals; Calcium Channels; Cell Membrane; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Cholestanol; Cholesterol; Disease Models, Animal; Mice; Mutation; Rats; Steroid Hydroxylases; Xanthomatosis, Cerebrotendinous

Topics: Animals; Bile Acids and Salts; Chemistry Techniques, Synthetic; Cholanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; HEK293 Cells; Hep G2 Cells; Humans; Ligands; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Targeted Therapy; Pruritus; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Small Molecule Libraries; Structure-Activity Relationship

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Gene Expression Regulation; Male; Mice; Mice, Knockout; MicroRNAs; Nuclear Receptor Co-Repressor 1

Topics: Animals; Blood-Brain Barrier; Chenodeoxycholic Acid; Corpus Callosum; Disease Models, Animal; Enzyme Activation; Fibrinolytic Agents; Humans; Ischemia; Male; Mice, Inbred C57BL; Neuroprotective Agents; Oligodendroglia; Protein C; Receptor, PAR-1; Receptors, Thrombin; Stroke; White Matter

Topics: Animals; Bacterial Translocation; Capillary Permeability; Chenodeoxycholic Acid; Diet, High-Fat; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Insulin Resistance; Intestinal Mucosa; Liver; Mice; Non-alcoholic Fatty Liver Disease; Protective Agents

Topics: Angiogenic Proteins; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Liver; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Probiotics; RNA-Binding Proteins; Signal Transduction; Ursodeoxycholic Acid

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Brain; Brain-Derived Neurotrophic Factor; Cell Line; Chenodeoxycholic Acid; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hippocampus; Humans; Mice; Neurons; Receptors, Cytoplasmic and Nuclear; Signal Transduction

Topics: Animals; Cells, Cultured; Chenodeoxycholic Acid; Disease Models, Animal; Drug Therapy, Combination; Hepatic Stellate Cells; Humans; Lipid Droplets; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Perilipin-1; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Transcriptional Activation; Treatment Outcome

Topics: Adipose Tissue, Brown; Animals; Body Mass Index; Chenodeoxycholic Acid; Cholestenones; Clostridiales; Cohort Studies; Diet, High-Fat; Disease Models, Animal; Disease Susceptibility; Gastrointestinal Microbiome; Gene Expression Regulation; Glucagon-Like Peptide 1; Humans; Ileum; Lithocholic Acid; Male; Metagenomics; Mice; Mice, Inbred C57BL; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Uncoupling Protein 1; Ursodeoxycholic Acid

Topics: alpha-Linolenic Acid; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Disease Models, Animal; Dysbiosis; Endometriosis; Feces; Female; Gastrointestinal Microbiome; Humans; Metabolomics; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S

Topics: Animals; Anticholesteremic Agents; Chenodeoxycholic Acid; Clostridioides difficile; Clostridium Infections; Diet, High-Fat; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; RNA-Binding Proteins

Topics: Animals; Atherosclerosis; Chenodeoxycholic Acid; Diet, High-Fat; Disease Models, Animal; Fast Foods; Hyperinsulinism; Hyperlipidemias; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, LDL; Transcriptome; Treatment Outcome

Topics: Animals; Azepines; Bile Acids and Salts; Cell Cycle Proteins; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Drug Interactions; Gene Knockdown Techniques; Humans; Liver; Liver Cirrhosis, Biliary; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Nuclear Proteins; Nuclear Receptor Co-Repressor 2; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Triazoles

Topics: Animals; Antiviral Agents; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Disease Models, Animal; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Mice; Organic Anion Transporters, Sodium-Dependent; Prospective Studies; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Symporters; Transplantation Chimera; Virus Internalization

Topics: Animals; Anxiety; Behavior, Animal; Brain; Chenodeoxycholic Acid; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Microglia; Sugars

Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Cartilage; Cell Line; Cell Survival; Chenodeoxycholic Acid; Cytokines; Disease Models, Animal; Gene Expression Regulation; Inflammation Mediators; Lipopolysaccharides; Male; Mice; NF-kappa B; Nitric Oxide; Osteoarthritis; RAW 264.7 Cells; Signal Transduction

Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Choline Deficiency; Colon; Diet; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Saponins

Topics: Adenosine Triphosphate; Animals; Arthritis, Experimental; Bone Marrow Cells; Chemokine CXCL2; Chenodeoxycholic Acid; Chronic Pain; Disease Models, Animal; Knee Joint; Male; Mast Cells; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligopeptides; Receptor, PAR-2; Receptors, Purinergic; Synovial Fluid

Topics: Animals; Apoptosis; Chenodeoxycholic Acid; Disease Models, Animal; Fast Foods; Inflammation; Liver Cirrhosis; Male; Mice; Mice, Knockout; MicroRNAs; Non-alcoholic Fatty Liver Disease; PPAR alpha; Receptors, Cytoplasmic and Nuclear

Topics: Animals; Bile Acids and Salts; Biliary Fistula; Chenodeoxycholic Acid; Disease Models, Animal; Feces; Intestinal Mucosa; Intestines; Liver; Liver Cirrhosis; Male; Metabolome; Metabolomics; Rats, Wistar; Tissue Distribution

Topics: Animals; Binding Sites; Chenodeoxycholic Acid; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Glucose; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Promoter Regions, Genetic; Protein Binding; Receptors, Cytoplasmic and Nuclear; Retinoid X Receptors; RNA, Messenger; Signal Transduction; Transcription Factor CHOP; Tretinoin

Topics: Animals; Body Weight; CD36 Antigens; Chenodeoxycholic Acid; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Cricetinae; Diet; Disease Models, Animal; Dyslipidemias; Gene Expression Regulation; Insulin Resistance; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Receptors, LDL

Topics: Animals; Biopsy; Chalcones; Chenodeoxycholic Acid; Collagen Type I; Collagen Type I, alpha 1 Chain; Diet, High-Fat; Disease Models, Animal; Galectin 3; Lipid Metabolism; Liraglutide; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Propionates; Time Factors; Weight Gain

Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Fibroblast Growth Factors; Gastrointestinal Tract; Intestine, Small; Liver; Liver Diseases; Parenteral Nutrition; Parenteral Nutrition, Total; Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 4; Receptors, Cytoplasmic and Nuclear; Short Bowel Syndrome; Swine

Topics: Animals; Arachidonic Acid; Cell Movement; Cells, Cultured; Chenodeoxycholic Acid; Cytochrome P-450 Enzyme System; Diet, High-Fat; Disease Models, Animal; Female; Gene Expression Regulation; Hepatocytes; Humans; Lipid Metabolism; Mice; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Signal Transduction; THP-1 Cells

Topics: Animals; Body Weight; Cell Death; Chenodeoxycholic Acid; Cytoprotection; Disease Models, Animal; Disease Progression; Gene Knockout Techniques; Hepatocytes; Insulin Resistance; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Receptor, Melanocortin, Type 4; Tumor Suppressor Protein p53

Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Chenodeoxycholic Acid; Disease Models, Animal; Epithelial-Mesenchymal Transition; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Cell Line; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Cholestasis, Intrahepatic; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Ethinyl Estradiol; Humans; Ileum; Liver; Male; Molecular Docking Simulation; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Steroid 12-alpha-Hydroxylase; Up-Regulation

Topics: Acute Kidney Injury; Administration, Oral; Animals; Chenodeoxycholic Acid; Disease Models, Animal; Humans; Kidney; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Nephritis; Oxidative Stress; Receptors, Cytoplasmic and Nuclear

Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; cdc25 Phosphatases; Chenodeoxycholic Acid; Cholestasis; Cyclin D1; Disease Models, Animal; Fibroblast Growth Factors; Gene Expression Regulation; Liver Regeneration; Male; Organ Size; Rats

Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Chenodeoxycholic Acid; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Tumor Necrosis Factor-alpha

Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Chenodeoxycholic Acid; Disease Models, Animal; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Disease Models, Animal; Drug Synergism; Female; Ketoconazole; Liver; Liver Function Tests; Rats, Sprague-Dawley

Topics: Animals; Biopsy; Chalcones; Chenodeoxycholic Acid; Disease Models, Animal; Liver Cirrhosis; Mice; PPAR alpha; Proof of Concept Study; Propionates; Transcription, Genetic

Topics: Animals; Blood Glucose; Chenodeoxycholic Acid; Diabetes, Gestational; Diet, High-Fat; Disease Models, Animal; Dyslipidemias; Female; Glucose Intolerance; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Pregnancy; Pregnancy Complications

Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Down-Regulation; Drug Evaluation, Preclinical; Hypertension, Portal; Liver Cirrhosis; Male; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction

Topics: Aminoquinolines; Animals; Bile Ducts; Blood-Brain Barrier; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Disease Models, Animal; Endothelial Cells; Ligation; Male; Microvessels; Occludin; Permeability; Phosphorylation; Pyrimidines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tight Junctions; Tissue Culture Techniques; Zonula Occludens-1 Protein; Zonula Occludens-2 Protein

Topics: Animals; Binding Sites; Cell Hypoxia; Cell Line; Chenodeoxycholic Acid; Disease Models, Animal; Hepatocytes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Failure, Chronic; Liver; Membrane Transport Proteins; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Response Elements; RNA Interference; Transfection; Up-Regulation

Topics: Ampicillin; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cholic Acids; Deoxycholic Acid; Disease Models, Animal; Feedback, Physiological; Humans; Mice; Mice, Knockout; Organic Anion Transporters, Sodium-Dependent; Phenotype; Receptors, Cytoplasmic and Nuclear; Symporters

Topics: Animals; Asthma; Base Sequence; Bronchitis; Chenodeoxycholic Acid; Cytokines; Disease Models, Animal; DNA Primers; Female; Mice; Mice, Inbred BALB C; Ovalbumin; Th2 Cells

Topics: Animals; Antihypertensive Agents; Chenodeoxycholic Acid; Disease Models, Animal; Endothelin-1; Hypertension; Mesenteric Arteries; NF-kappa B; Nitric Oxide Synthase; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Vascular Cell Adhesion Molecule-1; Vasoconstriction; Vasodilation

Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Chenodeoxycholic Acid; Concanavalin A; Disease Models, Animal; Fas Ligand Protein; fas Receptor; Female; Gastrointestinal Agents; Gene Expression Regulation; Hepatitis, Autoimmune; Hepatocytes; Interferon-gamma; Interleukin-2; Interleukin-4; Liver; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Tumor Necrosis Factor-alpha

Topics: Animals; Anterior Cruciate Ligament; Cartilage, Articular; Chenodeoxycholic Acid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Femur; Injections, Intra-Articular; Interleukin-1beta; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Osteoarthritis; Prostaglandins E; Rabbits; Synovial Membrane; X-Ray Microtomography

Topics: Animals; Body Weight; Chenodeoxycholic Acid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; Gluconeogenesis; Glucose-6-Phosphatase; Liver; Male; Phosphoenolpyruvate Carboxykinase (ATP); Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors

Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; DNA; Gene Expression Profiling; Gene Expression Regulation; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Non-alcoholic Fatty Liver Disease; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Transcriptional Activation

Topics: Animals; Apoptosis; Biomarkers; Cell Cycle; Cell Line; Cell Proliferation; Chenodeoxycholic Acid; Cytokines; Disease Models, Animal; Endothelial Cells; Hemodynamics; Hepatic Stellate Cells; Hepatocytes; Humans; Inflammation; Inflammation Mediators; Kupffer Cells; Lipopolysaccharides; Liver; Liver Cirrhosis; Male; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Portal Pressure; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thioacetamide; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Resistance

Topics: Animals; Blood Platelets; Calcium Signaling; Chenodeoxycholic Acid; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinogen; Genotype; Hemostasis; Humans; Isoxazoles; Ligands; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Cytoplasmic and Nuclear; Thrombosis; Time Factors

Topics: Adiposity; Animals; Chenodeoxycholic Acid; Diet, Atherogenic; Disease Models, Animal; Fatty Liver; Female; Inflammation; Liver; Mice; Mice, Inbred NOD; Mice, Obese; Obesity; Weight Gain

Topics: Adenosine Triphosphate; Animals; Bile Ducts; Caspase 3; Caspase Inhibitors; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Inflammasomes; Interleukin-1beta; Kupffer Cells; Ligation; Liver; Liver Cirrhosis; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Reactive Oxygen Species; Receptors, G-Protein-Coupled; RNA Interference; Signal Transduction; Transfection

Topics: Animals; Apoptosis; Autophagy; Biomarkers; Chenodeoxycholic Acid; Disease Models, Animal; Endotoxins; Ileum; Inflammation Mediators; Intestinal Mucosa; Intestines; Male; Permeability; Rats; Receptors, Cytoplasmic and Nuclear; Reperfusion Injury; Signal Transduction

Topics: Airway Remodeling; Animals; Bleomycin; Chenodeoxycholic Acid; Collagen; Disease Models, Animal; Fibrosis; Gene Expression Profiling; Immunohistochemistry; Inflammation; Lung; Male; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Ventricular Remodeling

Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cardiovascular Agents; CD11b Antigen; CD36 Antigens; Chenodeoxycholic Acid; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Hyperlipidemias; Interleukin-1beta; Interleukin-6; Ligands; Lipids; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Sterol Regulatory Element Binding Protein 1; Thiazolidinediones; Toll-Like Receptor 4; Transcription Factors; Tumor Necrosis Factor-alpha

Topics: Animals; Cell Line; Cell Line, Tumor; Chenodeoxycholic Acid; Disease Models, Animal; DNA-Binding Proteins; Female; Hepatocytes; Hepatomegaly; Homeodomain Proteins; Humans; Hypertrophy; Introns; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; Transcription Factors

Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Bile Acids and Salts; Carcinogens; Chenodeoxycholic Acid; Disease Models, Animal; Edema; Female; Indomethacin; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Male; Muscle, Skeletal; Obesity; Phosphorylation; Random Allocation; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors

Topics: Animals; Aorta; Apolipoproteins E; Calcinosis; Cattle; Cell Differentiation; Cells, Cultured; Chenodeoxycholic Acid; Chronic Disease; Disease Models, Animal; Kidney Diseases; Male; Mice; Mice, Knockout; Osteogenesis; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Triglycerides; Vascular Diseases

Topics: Animals; Caco-2 Cells; Chenodeoxycholic Acid; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Drug Evaluation, Preclinical; Gene Expression Regulation; Humans; Ileum; Inflammation Mediators; Inflammatory Bowel Diseases; Intestinal Absorption; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Case-Control Studies; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Concanavalin A; Cytoprotection; Disease Models, Animal; Female; Humans; Inflammation Mediators; Interferon-gamma; Interleukin-6; Liver; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha

Topics: Animals; Chenodeoxycholic Acid; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hypoglycemic Agents; Liver Diseases; Metabolic Diseases; Receptors, Cytoplasmic and Nuclear

Topics: Androgens; Animals; Biomarkers; Chenodeoxycholic Acid; Dietary Fats; Disease Models, Animal; Drug Evaluation, Preclinical; Estradiol; Fibrosis; Male; Metabolic Syndrome; Prostate; Prostatitis; Rabbits; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Testosterone

Topics: Animals; Animals, Newborn; Atrophy; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Fibroblast Growth Factors; Glucagon-Like Peptides; Intestinal Mucosa; Liver Diseases; Parenteral Nutrition, Total; Swine; Treatment Outcome

Topics: Androgens; Animals; Blood Glucose; Cell Movement; Chenodeoxycholic Acid; Cholesterol; Diet, High-Fat; Disease Models, Animal; Hypogonadism; Male; Metabolic Syndrome; Muscle Contraction; Myocytes, Smooth Muscle; Prostate; Rabbits; Receptors, Androgen; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Testosterone; Triglycerides; Triptorelin Pamoate; Urinary Bladder

Topics: Animals; Biomarkers; Chenodeoxycholic Acid; Cytokines; Dietary Carbohydrates; Disease Models, Animal; Fibrosis; Fructose; Kidney; Lipid Metabolism; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Nephritis; Oxidative Stress; Plasminogen Activator Inhibitor 1; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Transforming Growth Factor beta1

Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bile; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Cholestasis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cricetinae; Cytochrome P-450 CYP3A; Disease Models, Animal; Down-Regulation; Liver; Microsomes, Liver; Models, Chemical; Oxidoreductases, N-Demethylating; RNA, Messenger; Steroid 12-alpha-Hydroxylase; Steroid Hydroxylases

Topics: Adenoviridae; Alkaline Phosphatase; Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Disease Models, Animal; Gene Expression Regulation; Humans; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Phenotype; Phosphoproteins; Transfection

Topics: Animals; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Female; Intestinal Absorption; Liver; Tupaiidae

Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cocarcinogenesis; Colon; Colonic Neoplasms; Colostomy; Disease Models, Animal; Intestinal Polyps; Neoplasms, Experimental; Rats; Time Factors

Topics: Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; beta Catenin; Carcinogenicity Tests; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cytoskeletal Proteins; Dinoprostone; Disease Models, Animal; Duodenal Neoplasms; Duodenum; Female; Mice; Trans-Activators

Topics: Acute Disease; Amylases; Animals; Ascites; CD11 Antigens; CD18 Antigens; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Models, Animal; Hyperglycemia; Hypocalcemia; Interleukin-8; Laparotomy; Leukopenia; Ligation; Lipase; Necrosis; Neutrophils; Pancreas; Pancreatic Ducts; Pancreatitis; Rabbits; Respiratory Distress Syndrome; Sodium Chloride; Tumor Necrosis Factor-alpha; Up-Regulation

Topics: Albuminuria; Animals; Antibodies, Antinuclear; Blood Urea Nitrogen; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cytokines; Disease Models, Animal; Female; Gastrointestinal Agents; Hemocyanins; Immunization; Immunoglobulin G; Kidney; Liver; Lupus Nephritis; Mice; Mice, Inbred NZB; Spleen; Survival Rate; Uremia; Urodynamics; Ursodeoxycholic Acid

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chenodeoxycholic Acid; Colitis, Ulcerative; Disease Models, Animal; Guinea Pigs; Mesalamine; Ursodeoxycholic Acid

Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestyramine Resin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gastric Mucosa; Gastritis; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mice; Stomach Ulcer; Taurocholic Acid

Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary; Cricetinae; Deoxycholic Acid; Disease Models, Animal; Female; Hydroxymethylglutaryl CoA Reductases; Liver; Mesocricetus

Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Biopsy; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholic Acids; Deoxycholic Acid; Diet; Disease Models, Animal; Lithocholic Acid; Liver; Liver Function Tests; Macaca mulatta

Topics: Animals; Bile; Bile Acids and Salts; Biliary Fistula; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chromatography, Gas; Cricetinae; Deoxycholic Acid; Disease Models, Animal; Lithocholic Acid; Male; Mesocricetus; Proteins; Ursodeoxycholic Acid

Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Intracranial Embolism and Thrombosis; Male; Rabbits; Streptokinase; Taurochenodeoxycholic Acid; Thromboembolism

Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Disease Models, Animal; Hydroxymethylglutaryl CoA Reductases; Male; Sciuridae; Ursodeoxycholic Acid

Topics: Ampulla of Vater; Animals; Bile; Bile Acids and Salts; Biliary Tract Diseases; Cats; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Thin Layer; Deoxycholic Acid; Disease Models, Animal; Enterobacteriaceae Infections; Gallbladder; Liver; Muscle, Smooth; Perfusion; Pressure; Sodium; Sodium Chloride; Spasm; Time Factors

Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cholic Acids; Crystallization; Diet, Atherogenic; Disease Models, Animal; Liver; Male; Phospholipids; Rodentia; Time Factors; Triglycerides