Page last updated: 2024-08-21

chenodeoxycholic acid and Cirrhosis, Liver

chenodeoxycholic acid has been researched along with Cirrhosis, Liver in 96 studies

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-199046 (47.92)18.7374
1990's4 (4.17)18.2507
2000's3 (3.13)29.6817
2010's27 (28.13)24.3611
2020's16 (16.67)2.80

Authors

AuthorsStudies
Anstee, QM; Bonacci, M; Dufour, JF; Goodman, Z; Granston, T; Harrison, SA; Loomba, R; Natha, M; Ratziu, V; Rinella, ME; Sanyal, AJ; Shringarpure, R; Trylesinski, A; Venugopal, A; Younossi, Z1
Cai, Z; Deng, L; Geng, X; Hu, L; Jiao, S; Li, Z; Ren, Q; Wang, B; Yang, Y; Zhang, L; Zhou, Z1
El-Metwaly, S; Hassan, AA; Lotfy, A; Shiha, G; Soliman, R1
Abenavoli, L; Alvaro, D; Bertino, G; Brunetto, M; Calvaruso, V; Cannavò, M; Carbone, M; Cazzagon, N; Chessa, L; Claar, E; Coco, B; Colapietro, F; Cotugno, R; Cozzolongo, R; Cristoferi, L; Cuccorese, G; D'Amato, D; D'Antò, M; De Gasperi, E; De Vincentis, A; Distefano, M; Fiorini, C; Floreani, A; Frazzetto, E; Galati, G; Galli, A; Gerussi, A; Giannini, EG; Invernizzi, P; Izzi, A; Labanca, S; Lleo, A; Losito, F; Malinverno, F; Marconi, G; Marra, F; Marzioni, M; Morelli, O; Morgando, A; Mulinacci, G; Muratori, L; Niro, GA; Palermo, A; Palitti, VP; Pellicano, R; Pellicelli, A; Picardi, A; Pompili, M; Ponziani, F; Ronca, V; Rosina, F; Russello, M; Sacco, R; Saitta, C; Scaravaglio, M; Scifo, G; Simone, L; Storato, S; Terracciani, F; Tortora, A; Vanni, E; Vespasiani-Gentilucci, U; Viganò, M; Zolfino, T; Zuin, M1
Adekunle, F; Battezzati, PM; Bowlus, CL; Bruns, T; Carbone, M; Cazzagon, N; Corpechot, C; Dalekos, GN; Fisher, H; Flack, S; Floreani, A; Gatselis, NK; Gulamhusein, A; Hansen, BE; Hirschfield, GM; Hiu, S; Invernizzi, P; Janssen, HLA; Jones, D; Kareithi, D; Kowdley, KV; Lammers, WJ; Lindor, KD; Lleo, A; Londoño, MC; Malecha, E; Mason, AL; Mayne, T; Mayo, MJ; Mells, G; Mulcahy, V; Murillo Perez, CF; Ness, E; Nevens, F; Parés, A; Smith, R; Thorburn, D; Trauner, M; Trivedi, PJ; van der Meer, AJ; Verhelst, X; Wason, J1
Barve, S; Chen, K; Feng, W; Gu, Z; He, L; Jiang, M; Li, F; Liu, Q; Liu, Y; McClain, CJ; Shao, T; Song, Q; Zhang, L; Zhang, X; Zhou, Y; Zhu, F1
Bartneck, M; Levada, K; Omelyanchik, A; Rodionova, V; Weiskirchen, R1
Gulamhusein, AF; Hirschfield, GM1
Cui, S; Ge, C; Gonzalez, FJ; Guo, Y; Hao, H; He, Q; Huang, N; Pan, X; Wang, G; Wang, H; Zhang, P; Zhou, J1
Nakajima, A; Ogawa, Y; Okanoue, T; Sumida, Y; Yoneda, M1
Kowdley, KV; Shah, RA1
An, P; Huang, P; Jiang, LJ; Li, W; Li, Y; Lin, Y; Or, YS; Popov, YV; Qi, X; Vaid, KA; Wang, J; Wei, G; Zhang, S1
Attia, SL; Mouzaki, M; Softic, S1
Hou, MC; Hsieh, YC; Hsu, CF; Huang, CC; Huang, SF; Huang, YH; Lee, KC; Lee, TY; Li, TH; Lin, HC; Lin, MW; Liu, CW; Liu, HM; Tsai, YL; Yang, YY1
Attema, J; Caspers, MPM; de Ruiter, C; Kleemann, R; Menke, AL; Radhakrishnan, S; Salic, K; van den Hoek, AM; van Nieuwkoop, A; Verschuren, L; Worms, N1
Dou, B; Fan, S; Huang, C; Huang, J; Huang, L; Li, J; Liu, C; Zheng, P; Zhou, Z1
Anstee, QM; Barritt, AS; Bonacci, M; Cawkwell, G; Harrison, S; Loomba, R; Nader, F; Noureddin, M; Ratziu, V; Rinella, M; Sanyal, AJ; Schattenberg, JM; Stepanova, M; Wong, B; Younossi, ZM1
Afonso, MB; Borralho, PM; Carvalho, CC; Castro, RE; Cortez-Pinto, H; Duarte, A; Machado, MV; Rodrigues, CM; Rodrigues, PM; Simão, AL; Trindade, A1
Adorini, L; Aldini, R; Camborata, C; Cont, M; D'Errico, A; Degiovanni, A; Franco, P; Maroni, L; Roda, A; Spinozzi, S; Vasuri, F1
Andreone, P; Gitto, S; Guarneri, V; Sartini, A1
Drew, L1
Feigh, M; Gillum, MP; Hansen, HH; Jelsing, J; Kristiansen, MN; Rigbolt, KT; Tølbøl, KS; Veidal, SS; Vrang, N1
Biagioli, M; Carino, A; Fiorucci, S; Limongelli, V; Marchianò, S; Scarpelli, P; Zampella, A1
Asakawa, M; Goto, T; Itoh, M; Kai, T; Kanai, S; Ogawa, Y; Sakai, T; Shirakawa, I; Suganami, T; Yoneyama, T1
Abdelmalek, MF; Chalasani, NP; Chen, J; Ferguson, B; Kowdley, KV; Lee, L; Liberman, A; Loomba, R; McCullough, AJ; Neuschwander-Tetri, BA; Sanyal, AJ; Shapiro, D; Shringarpure, R; Terrault, N1
Abdelmalek, MF; Chalasani, N; Dasarathy, S; Ferguson, B; Kowdley, KV; Loomba, R; McCullough, AJ; Neuschwander-Tetri, BA; Sanyal, AJ; Shapiro, D; Shringarpure, R; Terrault, N1
Aguilera, L; Albillos, A; Martínez, J1
Brunt, EM; Kleiner, DE; Neuschwander-Tetri, BA; Sanyal, AJ; Wilson, LA1
Rockey, DC1
Adorini, L; Feigh, M; Fensholdt, LKD; Hansen, HH; Jelsing, J; Nielsen, JC; Papazyan, R; Rigbolt, KTG; Roth, JD; Veidal, SS; Vrang, N; Young, M1
Anstee, QM; Bedossa, P; Goodman, Z; Harrison, S; Loomba, R; MacConell, L; Ratziu, V; Rinella, M; Sanyal, AJ; Shah, A; Shringarpure, R; Younossi, Z1
Alukal, JJ; Thuluvath, PJ1
Elst, IV; Farre, R; Klein, S; Komuta, M; Laleman, W; Nevens, F; Roskams, T; Trebicka, J; Vanuytsel, T; Verbeke, L; Windmolders, P1
Hayashi, Y; Ishii, A; Jia, X; Kaneko, R; Kato, M; Kitamori, K; Naito, H; Nakajima, T; Nomura, M; Suzuki, Y; Yamori, Y; Yetti, H; Zaitsu, K1
Abdelmalek, MF; Brunt, EM; Chalasani, N; Clark, JM; Dasarathy, S; Diehl, AM; Doo, E; Hameed, B; Kleiner, DE; Kowdley, KV; Lavine, JE; Loomba, R; McCullough, A; Neuschwander-Tetri, BA; Sanyal, AJ; Terrault, N; Tonascia, J; Van Natta, ML1
Bosch, J; Fernández-Iglesias, A; Gracia-Sancho, J; Maeso-Díaz, R; Navarro-Zornoza, M1
Sanyal, AJ1
Andreone, P; Beuers, U; Bowlus, C; Drenth, JP; Floreani, A; Hansen, B; Hirschfield, GM; Hohenester, S; Hooshmand-Rad, R; Invernizzi, P; Jones, DE; Kowdley, KV; Lindor, KD; Luketic, V; MacConell, L; Marmon, T; Marschall, HU; Mazzella, G; Nevens, F; Pencek, R; Pockros, PJ; Pruzanski, M; Regula, J; Shah, H; Shapiro, D; Sheeron, S; Shiffman, M; Strasser, SI; Trauner, M; van Erpecum, KJ; Vargas, V; Vincent, C1
Farre, R; Govaere, O; Klein, S; Laleman, W; Mannaerts, I; Mazzone, M; Nevens, F; Schierwagen, R; Trebicka, J; van Grunsven, LA; Vander Elst, I; Verbeke, L; Wenes, M; Windmolders, P1
Dufour, JF; Perazzo, H1
Edwards, JE; Gosselin, NH; Hofmann, AF; LaCerte, C; Marier, JF; Peyret, T; Shapiro, D1
Lu, C; Shao, J; Xu, W; Yao, S; Zhang, F; Zheng, S1
Cai, W; Chen, Y; Gong, Z; Tian, C; Wang, P; Wu, J; Xu, C; Zhao, S; Zhou, J1
Beppu, T; Otsuka, H; Seyama, Y; Takikawa, H; Yamakawa, T1
Javitt, NB1
Nemeth, A; Samuelson, K; Strandvik, B1
Egberts, EH; Schomerus, H1
Amuro, Y; Endo, T; Higashino, K; Uchida, K; Yamamura, Y1
Aly, A; Johansson, C; Norman, A; Samuelson, K1
Danielsson, H; Gustafsson, J; Patteson, TE; Schwartz, CC; Swell, L; Vlahcevic, ZR1
de Heer, K; Kloeppel, G; Sauer, HD; Werner, B1
Bianchi, G; Gatta, A; Iervese, T; Magalotti, D; Marchesini, G; Merkel, C; Pisi, E; Zoli, M1
Kobayashi, M; Koike, M; Kurosawa, T; Murai, T; Nittono, H; Okuda, M; Okuda, S; Sakiyama, M; Takei, H; Tanaka, T; Unno, A; Yoshimura, T1
Chisaki, K; Goto, A; Hirata, Y; Hirose, K; Iida, H; Iwasawa, K; Komatsu, Y; Matsumoto, A; Miyamoto, K; Nagai, R; Nakajima, T; Okuda, Y; Omata, M; Shiratori, Y; Tada, M1
Harihara, Y; Hashizume, K; Hirata, M; Ito, M; Kawarasaki, H; Kita, Y; Kusaka, K; Makuuchi, M; Nishimuraj, M; Saito, S; Sano, K; Yoshino, H1
Faust, H; Gyr, K1
Gregory, DH; Prugh, MF; Swell, L; Vlahcevic, ZR1
Bereziat, G; Pepin, D; Polonovski, J; Wolf, C1
Angelico, M; Attili, AF; Cantafora, A; Capocaccia, L; Lombardi, M; Thau, A1
Angelico, M; Attili, AF; Bracci, F; Capocaccia, L; Di Biase, A; Paciscopi, L; Puoti, C1
Ast, E; Czygan, P; Fröhling, W; Kommerell, B; Raedsch, R; Stiehl, A1
Bochet, S; Borel, GA1
Angelin, B; Einarsson, K; Hellstrom, K1
Fujimoto, T; Higuchi, M; Matsuoka, Y; Matsuyama, Y; Morita, T; Tsujii, T1
Jänne, O; Mäentausta, O1
Standaert, LO1
Bursaux, CD1
Angelico, M; Attili, AF; Capocaccia, L1
Demers, LM; Hepner, GW1
Brandt, KH; Eyssen, H; Parmentier, G; van Berge Henegouwen, GP1
Admirant, WH; Earnest, DL; Stiehl, A1
Hashimoto, H; Makino, I; Nakagawa, S; Shinozaki, K; Yoshino, K1
Einarsson, K; HEllström, K; Schersten, T1
Elias, E; Sherlock, S; Summerfield, JA1
Cheney, H; Knodell, RG; Ostrow, JD1
Bloomer, JR; Klatskin, G; Milstein, HJ1
Leuschner, U1
Hedenborg, G; Jönsson, G; Norman, A; Wisén, O1
Hasegawa, T; Kashima, K; Nakajima, T; Nakashima, T; Okuno, T; Sakamoto, Y; Sano, A; Seto, Y; Shima, T1
Hashimoto, L; Marotta, F; Safran, P1
Adachi, Y; Itoh, T; Kurumi, Y; Nanno, T; Sawada, Y; Yamamoto, T; Yamazaki, K1
Iijima, T; Nambu, M1
Akashi, Y; Miyazaki, H; Nakayama, F; Yanagisawa, J1
Bély, M; Kocsár, L; Orbán, E; Romics, L; Ungár, P1
Barbare, JC; Chrétien, Y; Darnis, F; Islam, S; Poupon, R; Poupon, RE1
Kaye, MD; Mehta, SJ; Naylor, JL; Struthers, JE1
Cooper, NS; Fischer, CD; Mosbach, EH; Rothschild, MA1
Banwell, JG; Lockwood, DH; Nair, PP; Sherr, HP; White, JJ1
Kuroda, T; Okuda, K1
Fehér, T; Kazik, MH; Papp, J1
Greenfield, MF; Quarfordt, SH1
Russell, RI1
Bell, CC; McCormick, WC; Swell, L; Vlahcevic, ZR1
Erb, W; Haase, A; Leuschner, U1
Erb, W; Schreiber, J; Walczak, M1
Makino, I; Mashimo, K; Nakagawa, S; Shinozaki, K1

Reviews

14 review(s) available for chenodeoxycholic acid and Cirrhosis, Liver

ArticleYear
Magnetic-Assisted Treatment of Liver Fibrosis.
    Cells, 2019, 10-19, Volume: 8, Issue:10

    Topics: Animals; Benzamides; Benzothiazoles; Chenodeoxycholic Acid; Hepatic Stellate Cells; Humans; Imidazoles; Liver Cirrhosis; Macrophages; Magnetic Fields; Nanomedicine; Non-alcoholic Fatty Liver Disease; Pyridines; Sulfonamides

2019
Primary biliary cholangitis: pathogenesis and therapeutic opportunities.
    Nature reviews. Gastroenterology & hepatology, 2020, Volume: 17, Issue:2

    Topics: Adaptive Immunity; Animals; Autoimmunity; Bile Acids and Salts; Chenodeoxycholic Acid; Chloride-Bicarbonate Antiporters; Cholagogues and Choleretics; Dihydrolipoyllysine-Residue Acetyltransferase; Disease Progression; Environmental Exposure; Epigenesis, Genetic; Humans; Immunity, Innate; Liver Cirrhosis; Liver Cirrhosis, Biliary; MicroRNAs; Organic Anion Transporters, Sodium-Dependent; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Symporters; Ursodeoxycholic Acid

2020
Current and new pharmacotherapy options for non-alcoholic steatohepatitis.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:8

    Topics: Chenodeoxycholic Acid; Clinical Trials as Topic; Fibroblast Growth Factors; Glucagon-Like Peptides; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptors; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Treatment Outcome; Vitamin E

2020
Obeticholic acid for the treatment of nonalcoholic steatohepatitis.
    Expert review of gastroenterology & hepatology, 2020, Volume: 14, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chenodeoxycholic Acid; Clinical Trials as Topic; Disease Progression; Gastrointestinal Agents; Healthy Lifestyle; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear

2020
Evolving Role for Pharmacotherapy in NAFLD/NASH.
    Clinical and translational science, 2021, Volume: 14, Issue:1

    Topics: Adult; Benzhydryl Compounds; Chenodeoxycholic Acid; Child; Clinical Trials, Phase III as Topic; Fibroblast Growth Factors; Glucosides; Humans; Imidazoles; Isobutyrates; Liraglutide; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Oxazoles; Polyethylene Glycols; Pyridazines; Pyrimidines; Severity of Illness Index; Sulfoxides; Treatment Outcome; Uracil

2021
The use of obeticholic acid for the management of non-viral liver disease: current clinical practice and future perspectives.
    Expert review of gastroenterology & hepatology, 2018, Volume: 12, Issue:2

    Topics: Animals; Chenodeoxycholic Acid; Cholangitis, Sclerosing; Disease Models, Animal; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Treatment Outcome

2018
Risk stratification and treatment of primary biliary cholangitis.
    Revista espanola de enfermedades digestivas, 2019, Volume: 111, Issue:1

    Topics: Adult; Age Factors; Alkaline Phosphatase; Biomarkers; Budesonide; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; Disease Progression; Fibric Acids; Glucocorticoids; Humans; Liver Cirrhosis; Liver Transplantation; Middle Aged; Risk Assessment; Risk Factors; Sex Factors; Treatment Failure; Ursodeoxycholic Acid

2019
Reversal of NASH fibrosis with pharmacotherapy.
    Hepatology international, 2019, Volume: 13, Issue:5

    Topics: Benzamides; Chalcones; Chenodeoxycholic Acid; Disease Progression; Humans; Imidazoles; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Propionates; Pyridines; Risk Factors; Sulfoxides

2019
New cellular and molecular targets for the treatment of portal hypertension.
    Hepatology international, 2015, Volume: 9, Issue:2

    Topics: Acetates; Antioxidants; Biopterins; Chenodeoxycholic Acid; Cyclopropanes; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Leukotriene Antagonists; Liver Circulation; Liver Cirrhosis; Microvessels; Molecular Targeted Therapy; Naphthalenes; Neovascularization, Pathologic; Propionates; Quinolines; Sulfides; Vascular Resistance

2015
Use of farnesoid X receptor agonists to treat nonalcoholic fatty liver disease.
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:3

    Topics: Animals; Atherosclerosis; Chenodeoxycholic Acid; Humans; Insulin Resistance; Lipid Metabolism; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear

2015
The therapeutic landscape of non-alcoholic steatohepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:5

    Topics: Antioxidants; Chalcones; Chenodeoxycholic Acid; Disease Progression; Humans; Hypoglycemic Agents; Insulin Resistance; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Pioglitazone; Propionates; Randomized Controlled Trials as Topic; Thiazolidinediones; Vitamin E; Weight Loss

2017
[Caroli syndrome: the focal dilatation of intrahepatic bile ducts].
    Ergebnisse der inneren Medizin und Kinderheilkunde, 1981, Volume: 46

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Amyloidosis; Bile; Bile Duct Diseases; Bile Ducts, Intrahepatic; Biliary Dyskinesia; Chenodeoxycholic Acid; Child; Child, Preschool; Cholangiography; Cholangitis; Cholelithiasis; Female; Humans; Infant; Kidney; Kidney Diseases, Cystic; Liver; Liver Cirrhosis; Male; Middle Aged; Syndrome

1981
Disturbances of bile acid metabolism in parenchymal liver cell disease.
    Clinics in gastroenterology, 1977, Volume: 6, Issue:1

    Topics: Acute Disease; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholic Acids; Chronic Disease; Enterohepatic Circulation; Hepatitis; Humans; Infant, Newborn; Jaundice, Neonatal; Liver; Liver Cirrhosis; Liver Diseases; Phototherapy

1977
[Current status of treatment of gall stones with chenodeoxycholic acid].
    Tijdschrift voor gastro-enterologie, 1975, Volume: 18, Issue:1

    Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cricetinae; Diarrhea; Digestive System; Dogs; Haplorhini; Humans; Liver; Liver Cirrhosis; Macaca mulatta; Mice; Rabbits; Rats

1975

Trials

8 trial(s) available for chenodeoxycholic acid and Cirrhosis, Liver

ArticleYear
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
    Gastroenterology, 2022, Volume: 163, Issue:6

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022
Obeticholic Acid Impact on Quality of Life in Patients With Nonalcoholic Steatohepatitis: REGENERATE 18-Month Interim Analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2022, Volume: 20, Issue:9

    Topics: Adult; Aged; Chenodeoxycholic Acid; Double-Blind Method; Female; Fibrosis; Humans; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pruritus; Quality of Life

2022
Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis.
    Gastroenterology, 2019, Volume: 156, Issue:1

    Topics: Adult; Biomarkers; Biopsy; Chenodeoxycholic Acid; Clinical Enzyme Tests; Decision Support Techniques; Female; Gastrointestinal Agents; Humans; Ligands; Liver; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Predictive Value of Tests; Receptors, Cytoplasmic and Nuclear; Time Factors; Treatment Outcome; United States

2019
Relationship between three commonly used non-invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non-alcoholic steatohepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:5

    Topics: Adult; Biomarkers; Biopsy; Chenodeoxycholic Acid; Female; Humans; Liver; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; United States

2019
REGENERATE: Design of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis.
    Contemporary clinical trials, 2019, Volume: 84

    Topics: Chenodeoxycholic Acid; Dose-Response Relationship, Drug; Health Resources; Health Services; Humans; Liver Cirrhosis; Liver Transplantation; Longitudinal Studies; Non-alcoholic Fatty Liver Disease

2019
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial.
    Lancet (London, England), 2015, Mar-14, Volume: 385, Issue:9972

    Topics: Administration, Oral; Chenodeoxycholic Acid; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Treatment Outcome; Weight Loss

2015
A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.
    The New England journal of medicine, 2016, Aug-18, Volume: 375, Issue:7

    Topics: Adult; Aged; Alkaline Phosphatase; Bile Acids and Salts; Bone Density; Chenodeoxycholic Acid; Double-Blind Method; Female; Fibroblast Growth Factors; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Middle Aged; Pruritus

2016
Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage.
    Clinical and translational science, 2016, Volume: 9, Issue:6

    Topics: Adult; Area Under Curve; Chenodeoxycholic Acid; Computer Simulation; Female; Healthy Volunteers; Humans; Liver; Liver Cirrhosis; Male; Models, Biological; Reproducibility of Results

2016

Other Studies

74 other study(ies) available for chenodeoxycholic acid and Cirrhosis, Liver

ArticleYear
Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study.
    Journal of hepatology, 2022, Volume: 76, Issue:3

    Topics: Adult; Aged; Chenodeoxycholic Acid; Double-Blind Method; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Logistic Models; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Placebos

2022
Discovery of new and highly effective quadruple FFA1 and PPARα/γ/δ agonists as potential anti-fatty liver agents.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Animals; Chenodeoxycholic Acid; Drug Discovery; Gene Expression Regulation; Humans; Hypoglycemic Agents; Liver Cirrhosis; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Models, Molecular; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Protein Binding; Receptors, G-Protein-Coupled; Structure-Activity Relationship

2022
Umbilical Cord Mesenchymal Stem/Stromal Cells and Low-Dose Obeticholic Acid as a Possible Combined Treatment for Liver Fibrosis.
    Stem cell reviews and reports, 2022, Volume: 18, Issue:5

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis; Mesenchymal Stem Cells; Umbilical Cord

2022
Predictors of serious adverse events and non-response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid.
    Liver international : official journal of the International Association for the Study of the Liver, 2022, Volume: 42, Issue:11

    Topics: Albumins; Ascites; Bilirubin; Chenodeoxycholic Acid; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male

2022
Probiotic Lactobacillus rhamnosus GG Prevents Liver Fibrosis Through Inhibiting Hepatic Bile Acid Synthesis and Enhancing Bile Acid Excretion in Mice.
    Hepatology (Baltimore, Md.), 2020, Volume: 71, Issue:6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Fibroblast Growth Factors; Gastrointestinal Microbiome; Humans; Intestines; Lacticaseibacillus rhamnosus; Liver Cirrhosis; Mice; Mice, Knockout; Probiotics; Receptors, Cytoplasmic and Nuclear; Signal Transduction

2020
SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis.
    Nature communications, 2020, 01-13, Volume: 11, Issue:1

    Topics: Animals; Cells, Cultured; Chenodeoxycholic Acid; Disease Models, Animal; Drug Therapy, Combination; Hepatic Stellate Cells; Humans; Lipid Droplets; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Perilipin-1; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Transcriptional Activation; Treatment Outcome

2020
A novel non-bile acid FXR agonist EDP-305 potently suppresses liver injury and fibrosis without worsening of ductular reaction.
    Liver international : official journal of the International Association for the Study of the Liver, 2020, Volume: 40, Issue:7

    Topics: Animals; Chenodeoxycholic Acid; Fibrosis; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Steroids

2020
Obeticholic acid ameliorates hepatorenal syndrome in ascitic cirrhotic rats by down-regulating the renal 8-iso-PGF2α-activated COX-TXA2 pathway.
    Clinical science (London, England : 1979), 2020, 08-14, Volume: 134, Issue:15

    Topics: Animals; Apoptosis; Cell Line; Chenodeoxycholic Acid; Dinoprost; Drug Evaluation, Preclinical; Glutathione; Hepatorenal Syndrome; Liver Cirrhosis; Male; Oxidative Stress; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiobarbituric Acid Reactive Substances; Thromboxane A2; Vascular Resistance; Vasoconstriction

2020
A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology.
    Cells, 2020, 09-01, Volume: 9, Issue:9

    Topics: Animals; Atherosclerosis; Chenodeoxycholic Acid; Diet, High-Fat; Disease Models, Animal; Fast Foods; Hyperinsulinism; Hyperlipidemias; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, LDL; Transcriptome; Treatment Outcome

2020
Isotschimgine alleviates nonalcoholic steatohepatitis and fibrosis via FXR agonism in mice.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:6

    Topics: Animals; Carbon Tetrachloride; Chenodeoxycholic Acid; Diet; Inflammation; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phenyl Ethers

2021
miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice.
    Cell death & disease, 2017, 04-13, Volume: 8, Issue:4

    Topics: Animals; Apoptosis; Chenodeoxycholic Acid; Disease Models, Animal; Fast Foods; Inflammation; Liver Cirrhosis; Male; Mice; Mice, Knockout; MicroRNAs; Non-alcoholic Fatty Liver Disease; PPAR alpha; Receptors, Cytoplasmic and Nuclear

2017
Metabolic Profile of Obeticholic Acid and Endogenous Bile Acids in Rats with Decompensated Liver Cirrhosis.
    Clinical and translational science, 2017, Volume: 10, Issue:4

    Topics: Animals; Bile Acids and Salts; Biliary Fistula; Chenodeoxycholic Acid; Disease Models, Animal; Feces; Intestinal Mucosa; Intestines; Liver; Liver Cirrhosis; Male; Metabolome; Metabolomics; Rats, Wistar; Tissue Distribution

2017
Drug development: Sprint finish.
    Nature, 2017, 11-23, Volume: 551, Issue:7681

    Topics: Animals; Biotechnology; Cardiovascular Diseases; Chenodeoxycholic Acid; Clinical Trials as Topic; Drug Discovery; Drug Industry; Hepatitis C; Humans; Liver Cirrhosis; Mice; Molecular Targeted Therapy; Non-alcoholic Fatty Liver Disease

2017
Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis.
    World journal of gastroenterology, 2018, Jan-14, Volume: 24, Issue:2

    Topics: Animals; Biopsy; Chalcones; Chenodeoxycholic Acid; Collagen Type I; Collagen Type I, alpha 1 Chain; Diet, High-Fat; Disease Models, Animal; Galectin 3; Lipid Metabolism; Liraglutide; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Propionates; Time Factors; Weight Gain

2018
Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.
    Pharmacological research, 2018, Volume: 131

    Topics: Animals; Chenodeoxycholic Acid; Cholanes; Gene Expression Regulation; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta

2018
Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis.
    Scientific reports, 2018, 05-25, Volume: 8, Issue:1

    Topics: Animals; Body Weight; Cell Death; Chenodeoxycholic Acid; Cytoprotection; Disease Models, Animal; Disease Progression; Gene Knockout Techniques; Hepatocytes; Insulin Resistance; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Receptor, Melanocortin, Type 4; Tumor Suppressor Protein p53

2018
Improvements in Histologic Features and Diagnosis Associated With Improvement in Fibrosis in Nonalcoholic Steatohepatitis: Results From the Nonalcoholic Steatohepatitis Clinical Research Network Treatment Trials.
    Hepatology (Baltimore, Md.), 2019, Volume: 70, Issue:2

    Topics: Adult; Biopsy; Chenodeoxycholic Acid; Female; Humans; Hypoglycemic Agents; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pioglitazone; Randomized Controlled Trials as Topic; Receptors, Cytoplasmic and Nuclear; Retrospective Studies; Treatment Outcome; Vitamin E; Vitamins

2019
Editorial: Advances in Hepatology: 2019.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Antiviral Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; End Stage Liver Disease; Gastroenterology; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Non-alcoholic Fatty Liver Disease; Palliative Care

2019
Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH.
    Scientific reports, 2019, 06-21, Volume: 9, Issue:1

    Topics: Animals; Biopsy; Chalcones; Chenodeoxycholic Acid; Disease Models, Animal; Liver Cirrhosis; Mice; PPAR alpha; Proof of Concept Study; Propionates; Transcription, Genetic

2019
Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:6

    Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Down-Regulation; Drug Evaluation, Preclinical; Hypertension, Portal; Liver Cirrhosis; Male; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction

2014
A possible role of chenodeoxycholic acid and glycine-conjugated bile acids in fibrotic steatohepatitis in a dietary rat model.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:7

    Topics: Animals; Biomarkers; Chenodeoxycholic Acid; Cholic Acid; Chromatography, Liquid; Deoxycholic Acid; Diet, High-Fat; Fatty Liver; Liver; Liver Cirrhosis; Male; Non-alcoholic Fatty Liver Disease; Random Allocation; Rats; Tandem Mass Spectrometry

2014
FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis.
    Scientific reports, 2016, 09-16, Volume: 6

    Topics: Animals; Apoptosis; Biomarkers; Cell Cycle; Cell Line; Cell Proliferation; Chenodeoxycholic Acid; Cytokines; Disease Models, Animal; Endothelial Cells; Hemodynamics; Hepatic Stellate Cells; Hepatocytes; Humans; Inflammation; Inflammation Mediators; Kupffer Cells; Lipopolysaccharides; Liver; Liver Cirrhosis; Male; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Portal Pressure; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thioacetamide; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Resistance

2016
Dihydroartemisinin counteracts fibrotic portal hypertension via farnesoid X receptor-dependent inhibition of hepatic stellate cell contraction.
    The FEBS journal, 2017, Volume: 284, Issue:1

    Topics: Animals; Artemisinins; Carbon Tetrachloride; Cell Death; Chenodeoxycholic Acid; Gene Expression; Hepatic Stellate Cells; Hepatocytes; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Portal Vein; Pregnenediones; Protective Agents; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear

2017
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Adenosine Triphosphate; Animals; Bile Ducts; Caspase 3; Caspase Inhibitors; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Inflammasomes; Interleukin-1beta; Kupffer Cells; Ligation; Liver; Liver Cirrhosis; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Reactive Oxygen Species; Receptors, G-Protein-Coupled; RNA Interference; Signal Transduction; Transfection

2016
Serum concentrations of bile acid glucuronides in hepatobiliary diseases.
    Digestion, 1983, Volume: 27, Issue:4

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Male

1983
The Cheno Cooperative Study: its meaning for gallstone treatment.
    Hospital practice (Office ed.), 1982, Volume: 17, Issue:1

    Topics: Animals; Chenodeoxycholic Acid; Cholelithiasis; Humans; Liver Cirrhosis; Pan troglodytes

1982
Serum bile acids as markers of juvenile liver disease in alpha 1-antitrypsin deficiency.
    Journal of pediatric gastroenterology and nutrition, 1982, Volume: 1, Issue:4

    Topics: Adolescent; Adult; alpha 1-Antitrypsin Deficiency; Bile Acids and Salts; Chenodeoxycholic Acid; Child; Child, Preschool; Cholic Acids; Humans; Infant; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Male; Phenotype; Radioimmunoassay

1982
Urinary and fecal keto bile acids in liver cirrhosis.
    Clinica chimica acta; international journal of clinical chemistry, 1981, Aug-10, Volume: 114, Issue:2-3

    Topics: Adult; Ascites; Bile Acids and Salts; Chenodeoxycholic Acid; Deoxycholic Acid; Esophageal and Gastric Varices; Feces; Hepatic Encephalopathy; Humans; Lithocholic Acid; Liver Cirrhosis; Male; Middle Aged

1981
Evaluation of fasting serum bile acid concentration in patients with liver and gastrointestinal disorders.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:2

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholic Acids; Colitis, Ulcerative; Crohn Disease; Gastrointestinal Diseases; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests

1981
Bile acid metabolism in cirrhosis. VI. Sites of blockage in the bile acid pathways to primary bile acids.
    Gastroenterology, 1980, Volume: 79, Issue:4

    Topics: Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholic Acids; Humans; Liver Cirrhosis; Male; Middle Aged

1980
Protective effects of cholestyramine on liver cirrhosis induced by carbon tetrachloride in the rat.
    Gut, 1980, Volume: 21, Issue:10

    Topics: Animals; Carbon Tetrachloride; Chenodeoxycholic Acid; Cholestyramine Resin; Liver; Liver Cirrhosis; Male; Rats

1980
Prognostic significance of portal hemodynamics in patients with compensated cirrhosis.
    Journal of hepatology, 1993, Volume: 17, Issue:1

    Topics: Adult; Aged; Blood Flow Velocity; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Female; Hemodynamics; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Portal System; Portal Vein; Probability; Prognosis; Proportional Hazards Models; Regional Blood Flow; Serum Albumin; Survival Analysis; Ultrasonography; Ursodeoxycholic Acid

1993
3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase deficiency in a 23-year-old woman.
    Pediatrics international : official journal of the Japan Pediatric Society, 2000, Volume: 42, Issue:6

    Topics: 3-Hydroxysteroid Dehydrogenases; Adult; Chenodeoxycholic Acid; Cholic Acid; Female; Humans; Liver; Liver Cirrhosis; Metabolism, Inborn Errors; Steroid Isomerases; Ursodeoxycholic Acid; Vitamin K Deficiency

2000
Enhancement of endothelial nitric oxide production by chenodeoxycholic acids in patients with hepatobiliary diseases.
    Japanese heart journal, 2001, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Endothelium, Vascular; Female; Hemodynamics; Humans; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide; Ventricular Function, Left

2001
Immunosuppressive effect of chenodeoxycholic acid on natural killer cell activity in patients with biliary atresia and hepatitis C virus-related liver cirrhosis.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:5

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Bile Acids and Salts; Biliary Atresia; Bilirubin; Chenodeoxycholic Acid; Child, Preschool; Female; Hepatitis C; Humans; Killer Cells, Natural; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Platelet Count; Regression Analysis

2002
[New therapeutic possibilities in the diagnosis of congenital cystic bile duct dilatations (author's transl)].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1977, Volume: 126, Issue:3

    Topics: Bile Ducts; Biliary Dyskinesia; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholangiography; Cholangitis; Cysts; Diagnosis, Differential; Dilatation, Pathologic; Drainage; Female; Humans; Liver Cirrhosis; Liver Diseases; Syndrome

1977
[Plasma bile acids fractionnation by gas-liquid chromatography : application to hepatocellular deficiency investigation (author's transl)].
    Pathologie-biologie, 1977, Volume: 25, Issue:8

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Hepatitis, Viral, Human; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases

1977
Differences in serum bile acid composition between unoperated cirrhotic patients and patients with portacaval or mesocaval shunt.
    Digestion, 1979, Volume: 19, Issue:2

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Female; Humans; Liver Circulation; Liver Cirrhosis; Male; Methods; Middle Aged; Portacaval Shunt, Surgical

1979
Influence of portacaval anastomosis on serum and biliary unsulfated bile acid composition in patients with liver cirrhosis.
    Digestive diseases and sciences, 1979, Volume: 24, Issue:11

    Topics: Adult; Aged; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Female; Humans; Lithocholic Acid; Liver Cirrhosis; Male; Middle Aged; Portacaval Shunt, Surgical

1979
Pool size, synthesis, and turnover of sulfated and nonsulfated cholic acid and chenodeoxycholic acid in patients with cirrhosis of the liver.
    Gastroenterology, 1978, Volume: 74, Issue:3

    Topics: Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholic Acids; Humans; Liver Cirrhosis; Male; Sulfates

1978
[Clinical application of the radiolabeled bile salt tolerance test].
    Schweizerische medizinische Wochenschrift, 1978, Jul-29, Volume: 108, Issue:30

    Topics: Chenodeoxycholic Acid; Fatty Liver; Hepatitis, Viral, Human; Humans; Liver; Liver Cirrhosis; Radionuclide Imaging

1978
Effect of cholestyramine on bile acid kinetics in patients with portal cirrhosis of the liver. Evidence of a selective defect in the formation of cholic acid.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:12

    Topics: Aged; Chenodeoxycholic Acid; Cholestyramine Resin; Cholic Acids; Female; Humans; Hydroxylation; Kinetics; Liver; Liver Cirrhosis; Male; Middle Aged; Mixed Function Oxygenases

1978
Clinical significance of serum bile acid measurement in liver diseases.
    Gastroenterologia Japonica, 1978, Volume: 13, Issue:6

    Topics: Acute Disease; Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases

1978
Radioimmunoassay of conjugated cholic acid, chenodeoxycholic acid, and deoxycholic acid from human serum, with use of 125I-labeled ligands.
    Clinical chemistry, 1979, Volume: 25, Issue:2

    Topics: Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Pregnancy; Pregnancy Complications; Radioimmunoassay

1979
[Toxicity of chenodeoxycholic acid].
    Medecine & chirurgie digestives, 1975, Volume: 4 Suppl 1

    Topics: Animals; Chenodeoxycholic Acid; Colon; Haplorhini; Intestinal Absorption; Lithocholic Acid; Liver Cirrhosis; Papio; Rabbits; Rats

1975
Fasting and postprandial serum bile acids as a screening test for hepatocellular disease.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Eating; Fasting; Female; Hepatitis; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Time Factors

1977
Levels of immunoreactive glycine-conjugated bile acids in health and hepatobiliary disease.
    American journal of clinical pathology, 1976, Volume: 66, Issue:5

    Topics: Alcoholism; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Glycocholic Acid; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Radioimmunoassay

1976
Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis.
    Gut, 1976, Volume: 17, Issue:11

    Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Humans; Liver Cirrhosis; Sulfates

1976
Sulfation and renal excretion of bile salts in patients with cirrhosis of the liver.
    Gastroenterology, 1975, Volume: 68, Issue:3

    Topics: Adult; Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Humans; Kinetics; Lithocholic Acid; Liver Cirrhosis; Middle Aged; Spectrophotometry, Infrared; Sulfates; Tritium

1975
Sulfated and nonsulfated bile acids in urine, serum, and bile of patients with hepatobiliary diseases.
    Gastroenterology, 1975, Volume: 68, Issue:3

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Male; Sulfates

1975
The formation of bile acids in patients with portal liver cirrhosis.
    Scandinavian journal of gastroenterology, 1975, Volume: 10, Issue:3

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Female; Humans; Liver Cirrhosis; Male; Middle Aged

1975
Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones.
    Gastroenterology, 1975, Volume: 69, Issue:4

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Clofibrate; Female; Humans; Hypercholesterolemia; Liver Cirrhosis; Middle Aged; Remission, Spontaneous

1975
Effects of phototherapy on hepatic function in human alcoholic cirrhosis.
    Gastroenterology, 1976, Volume: 70, Issue:6

    Topics: Adult; Alcoholism; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Humans; Kinetics; Lipid Metabolism; Liver; Liver Cirrhosis; Male; Middle Aged; Phototherapy; Skin; Sulfobromophthalein

1976
Serum bile acids in alcoholic liver disease. Comparison with histological features of the disease.
    The American journal of digestive diseases, 1976, Volume: 21, Issue:4

    Topics: Alcoholism; Bile Acids and Salts; Biopsy; Chenodeoxycholic Acid; Humans; Liver; Liver Cirrhosis

1976
[Dissolution of cholesterol calculi using chenodeoxycholic acid].
    Deutsche medizinische Wochenschrift (1946), 1976, Jul-23, Volume: 101, Issue:30

    Topics: Alcoholism; Chenodeoxycholic Acid; Cholecystitis; Cholelithiasis; Cholestasis; Cholesterol; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis

1976
Equilibration of labelled and endogenous bile acids in patients with liver cirrhosis after administration of (24-14C)cholic and chenodeoxycholic acids.
    Scandinavian journal of clinical and laboratory investigation, 1991, Volume: 51, Issue:2

    Topics: Bile Acids and Salts; Biological Transport; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Feces; Glucuronates; Glycine; Humans; Lipoproteins; Liver Cirrhosis; Male; Middle Aged; Sulfates; Taurine

1991
Unusual trihydroxy bile acids in the urine of patients treated with chenodeoxycholate, ursodeoxycholate or rifampicin and those with cirrhosis.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:2

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Chromatography, Gas; Deoxycholic Acid; Gas Chromatography-Mass Spectrometry; Humans; Hydroxy Acids; Liver Cirrhosis; Rifampin; Ursodeoxycholic Acid

1990
[Application of high resolution liquid chromatography to the test of bile acid tolerance].
    Giornale di clinica medica, 1990, Volume: 71, Issue:1

    Topics: Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Middle Aged

1990
Determination of individual serum bile acids in chronic liver diseases: fasting levels and results of oral chenodeoxycholic acid tolerance test.
    Gastroenterologia Japonica, 1988, Volume: 23, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Chronic Disease; Fasting; Hepatitis; Humans; Liver Cirrhosis

1988
A combination therapy of vitamin K1 and bile acid on hemorrhagic diathesis in patients with decompensated liver cirrhosis.
    Gastroenterologia Japonica, 1988, Volume: 23, Issue:2

    Topics: Chenodeoxycholic Acid; Deoxycholic Acid; Drug Therapy, Combination; Female; Hemorrhagic Disorders; Humans; Liver Cirrhosis; Male; Ursodeoxycholic Acid; Vitamin K

1988
Bile acid metabolism in cirrhotic liver tissue--altered synthesis and impaired hepatic secretion.
    Clinica chimica acta; international journal of clinical chemistry, 1987, Sep-30, Volume: 168, Issue:2

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Female; Humans; Liver; Liver Cirrhosis; Male; Middle Aged

1987
[The importance of the analysis of serum bile acids in chronic liver diseases].
    Orvosi hetilap, 1986, Mar-30, Volume: 127, Issue:13

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Radioimmunoassay

1986
Fasting serum bile acid level in cirrhosis. A semi-quantitative index of hepatic function.
    Journal of hepatology, 1985, Volume: 1, Issue:6

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Fasting; Female; Humans; Kinetics; Liver; Liver Circulation; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged

1985
Biliary deoxycholate in patients with alcoholic cirrhosis.
    Gastroenterology, 1974, Volume: 67, Issue:4

    Topics: Administration, Oral; Adult; Alcoholism; Bile; Chenodeoxycholic Acid; Cholecystokinin; Cholic Acids; Deoxycholic Acid; Duodenum; Fasting; Female; Gallbladder; Humans; Intubation, Gastrointestinal; Lithocholic Acid; Liver Cirrhosis; Male; Methods; Middle Aged; Taurocholic Acid

1974
Effect of dietary chenodeoxycholic acid and lithocholic acid in the rabbit.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:10

    Topics: Animals; Appetite; Bile; Bile Acids and Salts; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Deoxycholic Acid; Diet; Lithocholic Acid; Liver; Liver Cirrhosis; Male; Rabbits

1974
Bile acid metabolism and hepatic disease following small bowel bypass for obesity.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:12

    Topics: Adult; Bile; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Fatty Liver; Female; Glycine; Humans; Ileum; Jejunum; Lithocholic Acid; Liver; Liver Cirrhosis; Liver Diseases; Male; Obesity; Postoperative Complications; Protein Deficiency; Sulfuric Acids; Taurine

1974
Bile acids in hepatic bile in liver disease.
    Acta hepato-gastroenterologica, 1974, Volume: 21, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Bile; Bile Acids and Salts; Biliary Fistula; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Glycocholic Acid; Hepatitis A; Humans; Liver; Liver Cirrhosis; Liver Diseases; Middle Aged; Taurocholic Acid

1974
Spectrofluorimetric determination of individual bile acids in biological fluids: peripheral plasma.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Mar-30, Volume: 44, Issue:3

    Topics: Acetylation; Adolescent; Adult; Aged; Animals; Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Thin Layer; Deoxycholic Acid; Dogs; Female; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Methylation; Middle Aged; Pruritus; Spectrometry, Fluorescence

1973
Estimation of cholesterol and bile acid turnover in man by kinetic analysis.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:8

    Topics: Adult; Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholesterol; Cholestyramine Resin; Cholic Acids; Deoxycholic Acid; Dietary Fats; Fats, Unsaturated; Female; Humans; Injections, Intravenous; Intubation, Gastrointestinal; Kinetics; Liver Cirrhosis; Male; Middle Aged; Obesity; Time Factors; Triglycerides; Tritium

1973
Clinical aspects of alterations in bile acid metabolism--the wrong bile acids in the wrong place.
    Scottish medical journal, 1973, Volume: 18, Issue:5

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Celiac Disease; Chenodeoxycholic Acid; Cholestasis; Colonic Diseases; Diarrhea; Hepatitis A; Ileum; Intestinal Mucosa; Intestine, Small; Lithocholic Acid; Liver Cirrhosis; Malabsorption Syndromes; Neomycin; Pancreatitis; Pruritus; Zollinger-Ellison Syndrome

1973
Cholic acid synthesis as an index of the severity of liver disease in man.
    Gut, 1973, Volume: 14, Issue:11

    Topics: Adult; Aged; Ascites; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Hepatic Encephalopathy; Humans; Kinetics; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Varicose Veins

1973
[Bile acid metabolism in hepatic tissue of healthy subjects and in patients with liver cirrhosis].
    Zeitschrift fur Gastroenterologie, 1973, Volume: 11, Issue:3

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Hepatic Encephalopathy; Humans; Lithocholic Acid; Liver; Liver Cirrhosis; Microscopy, Electron

1973
[Bile acids in the serum of patients with extrahepatic cholestasis with chronic liver diseases].
    Zeitschrift fur Gastroenterologie, 1973, Volume: 11, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chronic Disease; Deoxycholic Acid; Hepatic Encephalopathy; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases

1973
Measurement of sulfated and nonsulfated bile acids in human serum and urine.
    Journal of lipid research, 1974, Volume: 15, Issue:2

    Topics: Acute Disease; Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Chromatography, Ion Exchange; Chronic Disease; Gallbladder; Glycocholic Acid; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Neoplasm Metastasis; Spectrophotometry, Infrared; Sulfuric Acids; Taurocholic Acid

1974