Page last updated: 2024-08-21

chenodeoxycholic acid and Cholestasis

chenodeoxycholic acid has been researched along with Cholestasis in 143 studies

Research

Studies (143)

TimeframeStudies, this research(%)All Research%
pre-199062 (43.36)18.7374
1990's21 (14.69)18.2507
2000's17 (11.89)29.6817
2010's30 (20.98)24.3611
2020's13 (9.09)2.80

Authors

AuthorsStudies
Green, RM; Hoda, F; Ward, KL1
Camaioni, E; Clerici, C; Costantino, G; Fiorucci, S; Maloney, PR; Morelli, A; Parks, DJ; Pellicciari, R; Willson, TM1
Balasubramaniyan, N; Devereaux, MW; Orlicky, DJ; Sokol, RJ; Suchy, FJ1
Chen, B; Xiong, M; Yang, K; Yang, S; Zhang, J; Zhang, L; Zhu, S1
Bennett, AL; Dawson, PA; Donepudi, AC; Karpen, SJ; Klindt, C; Malla, SR; Moustafa, T; Pachura, KJ; Truong, JK; Zaufel, A1
Huang, X; Jiang, Z; Miao, Y; Tang, Q; Wang, J; Wu, Q; Xu, Y; Yu, Q; Yuan, Z; Zhang, H; Zhang, L; Zhang, Z1
Barron-Millar, B; Berlinguer-Palmini, R; Bird, TG; Borthwick, LA; Brain, JG; Burgoyne, RA; Cameron, RIT; Dyson, JK; Gee, LMV; Hall, Z; Hanson, PS; Holmes, E; Innes, B; Jones, DEJ; Jopson, L; Jurk, D; Kiourtis, C; Kirby, JA; LeBeau, FEN; Leslie, J; Luli, S; McKay, KRC; Mells, GF; Mokochinski, J; Morris, CM; Oakley, F; Palmer, J; Pechlivanis, A; Richardson, C; Sandford, RN; Smith, GR; Stoll, EA; Victorelli, S; Zaki, MYW1
Brites, D; Candeias Ramos, R; Catarino, C; Coutinho, H; Henriques, G; Lopes, AI; Rocha, S; Santos Silva, E; Santos-Silva, A; Teixeira, F1
Barve, S; Chen, K; Feng, W; Gu, Z; He, L; Jiang, M; Li, F; Liu, Q; Liu, Y; McClain, CJ; Shao, T; Song, Q; Zhang, L; Zhang, X; Zhou, Y; Zhu, F1
Feng, W; Hao, Z; Liu, Y; Ren, L; Song, Q; Zhang, L1
Fickert, P; Jungwirth, E; Kolb-Lenz, D; Krones, E; Lee, JM; Marschall, HU; Moore, DD; Panzitt, K; Pollheimer, M; Thallinger, GG; Thorell, A; Trauner, M; Wagner, M; Xiao, R1
Beaudoin, JJ; Bezençon, J; Brouwer, KLR; Fallon, JK; Sjöstedt, N1
Baldoni, M; Biagioli, M; Bordoni, M; Carino, A; Di Giorgio, C; Distrutti, E; Fiorucci, C; Fiorucci, S; Marchianò, S; Monti, MC; Morretta, E; Ricci, P; Roselli, R; Zampella, A1
Korf, H; Nevens, F; Smets, L; van der Merwe, S; Verbeek, J1
Chen, J; Chen, LF; Chiang, CM; Hu, X; Jung, H; Kemper, B; Kemper, JK; Sun, H; Wu, SY1
Arab, JP; Candia, R; Kulkarni, AV; Kumar, P; Padaki, NR; Premkumar, M; Reddy, DN; Sharma, M; Tevethia, HV1
Ferdinandusse, S; Vaz, FM1
Alvaro, D; Canonico, PL; Carbone, M; Craxi, A; Floreani, A; Gardini, I; Gasbarrini, A; Invernizzi, P; Kruger, P; Lanati, E; Marzioni, M; Mennini, FS; Muratori, L; Ronco, V; Vespasiani Gentilucci, U1
Beuers, U; Hohenester, S1
Burban, A; Guguen-Guillouzo, C; Guillouzo, A; Humbert, L; Rainteau, D; Sharanek, A1
Adorini, L; Beecher-Jones, T; Böhm, O; Chapman, R; Hirschfield, GM; Jones, D; Kowdley, KV; Luketic, V; Marschall, HU; Mason, A; Parés, A; Pencek, R; Poupon, R; Rust, C; Schramm, C; Sciacca, C; Shapiro, D; Vincent, C1
Cui, Y; Li, R; Ren, Y; Wang, C; Xiong, X; Zhang, Y1
Bergasa, NV1
Ashby, K; Borlak, J; Chen, M; Mehta, R; Navarro Almario, EE; Tong, W1
Blomenkamp, K; Greenspon, J; Guzman, MA; Heafner, N; Kakarla, V; Korremla, N; Kumar Jain, A; Manithody, C; Phillips, W; Pochampally, S; Price, A; Ratchford, T; Saxena, S; Villalona, G; Westrich, M1
Goldstein, J; Levy, C1
Dai, DL; Liu, SX; Setchell, KD; Shi, LN; Wang, HH; Wang, JS; Wen, FQ; Yang, QH; Zhao, J; Zhou, SM1
Aguilera, L; Albillos, A; Martínez, J1
Alles, LK; Damink, SWO; de Haan, L; de Waart, DR; Ergin, B; Heger, M; Jansen, PL; Lionarons, DA; Maas, A; Olthof, PB; Reiniers, MJ; Schaap, FG; Uz, Z; van Golen, RF; van Gulik, TM; Verheij, J1
Fickert, P; Heinemann, A; Höfler, G; Liu, L; Müller, H; Obermayer-Pietsch, B; Panzitt, K; Platzer, W; Racedo, S; Theiler-Schwetz, V; Wagner, M; Zaufel, A; Zollner, G1
Carey, EJ; Yokoda, RT1
Barbier, O; Białek, A; Caron, P; Milkiewicz, P; Perreault, M; Trottier, J; Verreault, M1
DeMorrow, S; Frampton, G; Galindo, C; McMillin, M; Pae, HY; Quinn, M1
Annaert, P; Chatterjee, S; Covens, K; Farre, R; Komuta, M; Laleman, W; Nevens, F; Roskams, T; Trebicka, J; Vander Elst, I; Vanuytsel, T; Verbeke, L; Verbinnen, B; Verhaegen, J; Windmolders, P1
Cai, W; Che, Y; Jia, W; Kwee, S; Pan, W; Wang, J; Wen, J; Wong, L; Xiao, Y; Xie, G; Yan, W; Zhang, T; Zhou, K; Zhou, Y1
Ali, AH; Lindor, KD1
Alawad, AS; Levy, C1
Hassan, HM; Jiang, Z; Li, X; Liu, R; Sun, R; Yang, H; Yuan, Z; Zhang, L1
Cai, W; Chen, Y; Gong, Z; Tian, C; Wang, P; Wu, J; Xu, C; Zhao, S; Zhou, J1
Clayton, PT; Hadzić, N; Mieli-Vergani, G; Portmann, BC; Subramaniam, P1
Aehlen, A; Ehmer, U; Erichsen, TJ; Kalthoff, S; Manns, MP; Strassburg, CP1
Hashimoto, T; Kimura, A; Kurosawa, T; Matsuishi, T; Mizuochi, T; Nittono, H; Seki, Y; Takahashi, T; Takao, A; Takei, H; Ueki, I1
Black, DD; Helms, RA; Tillman, EM1
Burrin, DG; Holst, JJ; Jain, AK; Moore, DD; Stoll, B1
Hasegawa, T; Hayashi, S; Homma, K; Hoshina, T; Ihara, K; Kimura, A; Kurosawa, T; Matsuishi, T; Mizuochi, T; Morimura, T; Nittono, H; Ohno, Y; Ohtake, A; Seki, Y; Takahashi, T; Takei, H1
Bouscarel, B; Ceryak, S; Doy, M; Fukushima, S; Honda, A; Ikegami, T; Matsuzaki, Y; Shoda, J; Tanaka, N; Yoshida, S1
Palmeira, CM; Rolo, AP; Wallace, KB1
Clayton, PT; Mann, A; Mieli-Vergani, G; Sistermans, E; Verrips, A; Wevers, R1
Hugosson, C; Khorsheed, SS; Nazer, H1
Claudel, T; Kuipers, F; Staels, B; Sturm, E1
Antonelli, E; Castellani, D; Clerici, C; Fiorucci, S; Goodwin, B; Morelli, A; Orlandi, S; Pellicciari, R; Pruzanski, M; Russo, G; Sabatino, G; Sadeghpour, BM; Willson, TM1
Chen, J; Raymond, K1
Hirosawa, K; Ito, S; Kato, K; Miyoshi, T; Yamakawa, T1
Tangedahl, TN1
Angelini, G; Antolini, G; Cavallini, G; Franchini, CA; Fratton, S; Micciolo, R; Scuro, LA; Tonon, M; Vaona, B1
Beppu, T; Otsuka, H; Seyama, Y; Takikawa, H; Yamakawa, T1
Kanai, S; Kitani, K2
Bartholomew, C; Billing, BH; Dooley, JS; Summerfield, JA1
Heikkinen, J; Järvinen, PA; Kirkinen, P; Mäentausta, O; Ylöstalo, P1
Mansurov, KhKh; Mansurova, FKh; Mirzoeva, MIu1
Czygan, P; Raedsch, R; Rudolph, G; Stiehl, A; Walker, S1
Balistreri, WF; Farrell, MK; Heubi, JE; Suchy, FJ1
Maile, PA; Woodman, DD1
Becher, MS; Gerok, W; Kremer, B; Schmidt, K; Schölmerich, J1
Bartholomew, TC; Billing, BH; Corbett, CL; Summerfield, JA1
Fehér, T; Loi, HG; Magyar, I1
Barton, P; Lechner, G; Maier, A; Mühlbacher, F; Steininger, R1
Casteels, M; Clayton, PT; Lawson, AM; Mieli-Vergani, G1
Bonnefis, MT; Calmus, Y; Chereau, C; Podevin, P; Poupon, R; Veyrunes, C1
Ayyad, N; Cohen, BI; Hoshita, T; Kihira, K; Mikami, T; Mosbach, EH; Yoshii, M1
LaRusso, NF; Marks, DL; McNiven, MA1
Ishida, T; Kaneko, JJ; Tomoda, I; Washizu, M; Washizu, T1
Ballet, F; Boucher, E; Calmus, Y; Franco, D; Gane, P; Hillaire, S; Moukthar, M; Poupon, R1
Bruining, HA; den Toom, R; Nijs, HG; Plaisier, PW; Terpstra, OT; van der Hul, RL1
Barabino, A; Clayton, PT; Johnson, AW; Marazzi, MG; Mills, KA1
Bernard, B; Bouvier, E; Cabrol, A; Cadranel, JF; Dorent, R; Gandjbakhch, I; Gerhardt, M; Ghoussoub, JJ; Lunel, F; Myara, A; Opolon, P; Trivin, F1
Azer, SA; Byth, K; Coverdale, SA; Farrell, GC; Stacey, NH1
Kimura, A; Kurosawa, T; Mahara, R; Murai, T; Tohma, M1
Blanc, MC; Bonnefis, MT; Podevin, P; Poupon, R; Vaubourdolle, M; Veyrunes, C1
Fujisawa, T; Hoshiyama, A; Inoue, T; Kato, H; Kimura, A; Kurosawa, T; Murai, T; Nakashima, E; Sata, M; Suzuki, M; Tohma, M; Yamashita, Y1
Benedetti, P; de Lalla, F; Fabris, P; Mazzella, G; Nicolin, R; Pellizzer, G; Tositti, G; Zanetti, AR1
Kimura, A; Kurosawa, T; Nittono, H; Takei, H1
Anna, M; Antonio, C; Azzaroli, F; Bovicelli, L; Colecchia, A; Constance, M; Davide, F; Enrico, R; Festi, D; Francesco, A; Giovanni, N; Giuliana, S; Luciano, B; Mazzella, G; Miracolo, A; Mwangemi, C; Nicola, R; Nigro, G; Patrizia, S; Rizzo, N; Roda, E; Simonazzi, G; Simoni, P1
Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP1
Chisaki, K; Goto, A; Hirata, Y; Hirose, K; Iida, H; Iwasawa, K; Komatsu, Y; Matsumoto, A; Miyamoto, K; Nagai, R; Nakajima, T; Okuda, Y; Omata, M; Shiratori, Y; Tada, M1
Dick, B; Frey, BM; Frey, FJ; Odermatt, A; Quattropani, C; Vogt, B1
Azzaroli, F; Ferrara, F; Festi, D; Giovanelli, S; Liva, S; Mazzella, G; Nigro, G; Roda, E1
Dick, B; Frey, FJ; Odermatt, A; Rochat, MK; Stauffer, AT1
Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP; Santos, MS; Seiça, R1
Brunner, H; Grabner, G; Horak, W1
Thomassen, PA1
Laatikainen, TJ1
Perman, JA; Watkins, JB1
Mosbach, EH; Salen, G; Shefer, S; Zaki, FG1
Hofmann, AF; van Berge Henegouwen, GP1
Amuro, Y; Endo, T; Higashino, K; Uchida, K; Yamamura, Y1
Hesso, AE; Laatikainen, TJ; Lehtonen, PJ1
Paumgartner, G; Weber, M1
Laatikainen, T2
Fujimoto, T; Higuchi, M; Matsuoka, Y; Matsuyama, Y; Morita, T; Tsujii, T1
Jänne, O; Mäentausta, O1
Ikonen, E; Laatikainen, T1
Bloomer, JR; Ghent, CN; Klatskin, G1
Demers, LM; Hepner, GW1
Brandt, KH; Eyssen, H; Parmentier, G; van Berge Henegouwen, GP1
Hashimoto, H; Makino, I; Nakagawa, S; Shinozaki, K; Yoshino, K1
Bloomer, JR; Boyer, JL1
Sturdevant, RA1
Hesso, A; Laatikainen, T1
Hesse, W; Liersch, MA1
Grabner, G; Horak, W1
Back, P1
Leuschner, U1
Guma, C; Viola, L1
Egestad, B; Marschall, HU; Matern, H; Matern, S; Sjövall, J; Wietholtz, H1
Lehnert, W; Marschall, HU; Matern, H; Matern, S; Schill, A; Schumacher, B; Sjövall, J1
Kage, M; Kimura, A; Kurosawa, T; Mahara, R; Nittono, H; Tohma, M; Yuge, K; Yukizane, S1
Berenson, MM; Bjorkman, DJ; Gunther, C; Samowitz, WS1
Baumgartner, U; Gerok, W; Miyai, K; Schölmerich, J1
Kanai, S; Kitani, K; Ohta, M1
Bailey, ME; Cahill, CJ; Pain, JA1
Bailey, ME; Pain, JA1
Fujima, T; Matsuura, K; Miyazaki, H; Shoda, J; Umahara, R1
Andersson, S; Clayton, PT; Egestad, B; Lawson, AM; Leonard, JV; Setchell, KD; Sjövall, J1
Norman, A; Strandvik, B3
Admirand, WH; Stiehl, A; Thaler, MM2
Burton, JL; Heaton, KW; Kirby, J1
George, P1
Murphy, GM; Signer, E1
Stiehl, A1
Makino, I; Mashimo, K; Nakagawa, S; Shinozaki, K1
Gartner, LM; Goldberg, H; Hollander, M; Javitt, NB; Kok, E; Morrissey, KP; Siegel, E1
Wheeler, HO1
Russell, RI1
Erb, W; Schreiber, J; Walczak, M1
Liersch, M; Stiehl, A1
Chen, T; Leevy, CM; Zaki, FG1

Reviews

18 review(s) available for chenodeoxycholic acid and Cholestasis

ArticleYear
Efficacy and safety of obeticholic acid in liver disease-A systematic review and meta-analysis.
    Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:3

    Topics: Chenodeoxycholic Acid; Cholestasis; Humans; Liver Cirrhosis, Biliary; Non-alcoholic Fatty Liver Disease; Pharmaceutical Preparations; Ursodeoxycholic Acid

2021
Bile acid analysis in human disorders of bile acid biosynthesis.
    Molecular aspects of medicine, 2017, Volume: 56

    Topics: Adult; Animals; Chenodeoxycholic Acid; Cholestasis; Cholesterol; Cholic Acid; Enterohepatic Circulation; Homeostasis; Humans; Infant; Intestinal Mucosa; Intestines; Liver; Mass Spectrometry; Spastic Paraplegia, Hereditary; Zellweger Syndrome

2017
[Chronic cholestatic liver diseases : Differential diagnosis, pathogenesis and current treatment in adults].
    Der Internist, 2017, Volume: 58, Issue:8

    Topics: Adult; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Humans; Liver Diseases; Ursodeoxycholic Acid

2017
Review article: therapeutic bile acids and the risks for hepatotoxicity.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:12

    Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Humans; Liver

2018
Novel and emerging therapies for cholestatic liver diseases.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:9

    Topics: Bile Acids and Salts; Budesonide; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Drug Therapy, Combination; Elasticity Imaging Techniques; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2018
Infant cholestasis patient with a novel missense mutation in the
    World journal of gastroenterology, 2018, Sep-21, Volume: 24, Issue:35

    Topics: Chenodeoxycholic Acid; Cholestasis; Gastrointestinal Agents; Humans; Infant, Newborn; Loss of Heterozygosity; Male; Mutation, Missense; Oxidoreductases; Sequence Alignment; Steroid Metabolism, Inborn Errors; Time Factors; Treatment Outcome

2018
Risk stratification and treatment of primary biliary cholangitis.
    Revista espanola de enfermedades digestivas, 2019, Volume: 111, Issue:1

    Topics: Adult; Age Factors; Alkaline Phosphatase; Biomarkers; Budesonide; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; Disease Progression; Fibric Acids; Glucocorticoids; Humans; Liver Cirrhosis; Liver Transplantation; Middle Aged; Risk Assessment; Risk Factors; Sex Factors; Treatment Failure; Ursodeoxycholic Acid

2019
Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:10

    Topics: Adult; Biliary Tract; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; End Stage Liver Disease; Humans; Immunologic Factors; Life Expectancy; Prevalence; Prognosis; Treatment Outcome; Ursodeoxycholic Acid

2019
Obeticholic acid for the treatment of primary biliary cholangitis.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:13

    Topics: Animals; Autoimmune Diseases; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; End Stage Liver Disease; Genome-Wide Association Study; Humans; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2016
FXR Agonists: From Bench to Bedside, a Guide for Clinicians.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Animals; Azepines; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Drug Evaluation, Preclinical; Gastrointestinal Agents; Hepatitis, Autoimmune; Humans; Hypertension, Portal; Indoles; Isoxazoles; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Biliary; Liver Diseases; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2016
The farnesoid X receptor: a novel drug target?
    Expert opinion on investigational drugs, 2004, Volume: 13, Issue:9

    Topics: Animals; Benzene Derivatives; Caprylates; Chenodeoxycholic Acid; Cholestasis; DNA-Binding Proteins; Humans; Hyperlipidemias; Hypolipidemic Agents; Molecular Structure; Phenyl Ethers; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2004
Bile acid metabolism in infants and children.
    Clinics in gastroenterology, 1977, Volume: 6, Issue:1

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cystic Fibrosis; Diarrhea; Digestive System; Enterohepatic Circulation; Female; Fetus; Gallbladder; Gastrointestinal Diseases; Humans; Infant; Infant, Newborn; Liver; Pregnancy; Taurine

1977
Inborn errors of bile acid synthesis.
    Clinics in gastroenterology, 1977, Volume: 6, Issue:1

    Topics: Animals; Bile Acids and Salts; Bile Ducts, Intrahepatic; Chemical Phenomena; Chemistry; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Humans; Liver; Metabolism, Inborn Errors; Xanthomatosis

1977
Clinical aspects of disturbances in the enterohepatic circulation of bile acids in man: the cholanopathies.
    The Netherlands journal of medicine, 1978, Volume: 21, Issue:6

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Celiac Disease; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholic Acids; Colonic Neoplasms; Deoxycholic Acid; Diarrhea; Humans; Intestinal Diseases; Intestine, Small; Lipid Metabolism; Lithocholic Acid; Liver; Liver Circulation; Malabsorption Syndromes; Portal System

1978
Disorders of the extrahepatic bile ducts.
    Clinics in gastroenterology, 1973, Volume: 2, Issue:1

    Topics: Ampulla of Vater; Anti-Bacterial Agents; Bile Duct Neoplasms; Bile Ducts; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholangiography; Cholangitis; Cholecystectomy; Cholelithiasis; Cholestasis; Common Bile Duct; Cysts; Duodenal Neoplasms; Gallstones; Humans; Iatrogenic Disease

1973
Bile acid metabolism in infants and children.
    Gut, 1974, Volume: 15, Issue:2

    Topics: Bile; Bile Acids and Salts; Biological Transport, Active; Chenodeoxycholic Acid; Child; Child, Preschool; Cholestasis; Cholesterol; Cholic Acids; Deoxycholic Acid; Humans; Infant; Infant Nutrition Disorders; Infant, Newborn; Lithocholic Acid; Liver; Liver Diseases; Malabsorption Syndromes; Surface Properties

1974
Sulfation of bile salts: a new metabolic pathway.
    Digestion, 1974, Volume: 11, Issue:5-6

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Humans; Lithocholic Acid; Liver; Rats; Sulfates

1974
Differential diagnosis of cholestasis.
    Advances in internal medicine, 1971, Volume: 17

    Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts; Bile Ducts, Intrahepatic; Bilirubin; Cell Division; Chenodeoxycholic Acid; Cholangiography; Cholestasis; Cholic Acids; Coloring Agents; Diagnosis, Differential; Humans; Liver; Liver Function Tests; Mitochondria, Liver; Pruritus; Vitamin K

1971

Trials

6 trial(s) available for chenodeoxycholic acid and Cholestasis

ArticleYear
A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:5

    Topics: Adult; Alkaline Phosphatase; Chenodeoxycholic Acid; Cholestasis; Double-Blind Method; Female; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2018
The biliary excretion of sulphated and non-sulphated bile acids and bilirubin in patients with external bile drainage.
    Clinical science (London, England : 1979), 1984, Volume: 67, Issue:1

    Topics: Aged; Bile; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Drainage; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Middle Aged; Secretory Rate; Time Factors

1984
Sequential changes in serum levels of individual bile acids in patients with chronic cholestatic liver disease.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:3

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholangitis, Sclerosing; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged; Predictive Value of Tests; Prognosis; Survival Rate

1996
Effect of ursodeoxycholic acid administration in patients with acute viral hepatitis: a pilot study.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Hepatitis Antibodies; Hepatitis Viruses; Hepatitis, Viral, Human; Humans; Male; Middle Aged; Pilot Projects; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Treatment Outcome; Ursodeoxycholic Acid

1999
Ursodeoxycholic acid administration in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers.
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:3

    Topics: Adult; Amniotic Fluid; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Dose-Response Relationship, Drug; Female; Fetal Blood; Humans; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pruritus; Ursodeoxycholic Acid

2001
Bile salts, endotoxin and renal function in obstructive jaundice.
    Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:6

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Creatine; Deoxycholic Acid; Drug Evaluation; Endotoxins; Humans; Intraoperative Care; Kidney; Mannitol; Postoperative Complications; Premedication

1987

Other Studies

119 other study(ies) available for chenodeoxycholic acid and Cholestasis

ArticleYear
Molecular cloning and characterization of the murine bile salt export pump.
    Gene, 2000, Jan-04, Volume: 241, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line; Cell Membrane; Cholagogues and Choleretics; Cholestasis; Cloning, Molecular; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Rats; Sequence Homology, Amino Acid; Taurocholic Acid; Transfection

2000
6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Anticholesteremic Agents; Cell Line; Chenodeoxycholic Acid; Cholestasis; DNA-Binding Proteins; Humans; Ligands; Liver; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Transcription Factors

2002
miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis.
    The Journal of biological chemistry, 2021, Volume: 297, Issue:6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Gene Expression Regulation; Male; Mice; Mice, Knockout; MicroRNAs; Nuclear Receptor Co-Repressor 1

2021
A high bile acid environment promotes apoptosis and inhibits migration in pancreatic cancer.
    Bioengineered, 2022, Volume: 13, Issue:3

    Topics: Apoptosis; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Humans; Pancreatic Neoplasms; Reactive Oxygen Species

2022
Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury.
    Journal of lipid research, 2022, Volume: 63, Issue:9

    Topics: Animals; Bile Acids and Salts; Carrier Proteins; Chenodeoxycholic Acid; Cholestasis; Cyclic N-Oxides; Female; Humans; Inflammation; Liver; Male; Membrane Glycoproteins; Mice; Tropanes

2022
Obeticholic acid aggravates liver injury by up-regulating the liver expression of osteopontin in obstructive cholestasis.
    Life sciences, 2022, Oct-15, Volume: 307

    Topics: Alkaline Phosphatase; Animals; Chenodeoxycholic Acid; Cholestasis; Fibrosis; Hydroxyproline; Liver; Mice; Osteopontin

2022
Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice.
    The American journal of pathology, 2023, Volume: 193, Issue:1

    Topics: Animals; Bile Ducts; Chenodeoxycholic Acid; Cholestasis; Humans; Ligation; Liver; Memory, Short-Term; Mice

2023
Bile acids profile and redox status in healthy infants.
    Pediatric research, 2023, Volume: 93, Issue:7

    Topics: Bile Acids and Salts; Biomarkers; Chenodeoxycholic Acid; Cholestasis; Cross-Sectional Studies; Female; Glutathione Disulfide; Humans; Infant; Infant, Newborn; Oxidation-Reduction; Oxidative Stress

2023
Probiotic Lactobacillus rhamnosus GG Prevents Liver Fibrosis Through Inhibiting Hepatic Bile Acid Synthesis and Enhancing Bile Acid Excretion in Mice.
    Hepatology (Baltimore, Md.), 2020, Volume: 71, Issue:6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Fibroblast Growth Factors; Gastrointestinal Microbiome; Humans; Intestines; Lacticaseibacillus rhamnosus; Liver Cirrhosis; Mice; Mice, Knockout; Probiotics; Receptors, Cytoplasmic and Nuclear; Signal Transduction

2020
Probiotic Lactobacillus rhamnosus GG prevents progesterone metabolite epiallaopregnanolone sulfate-induced hepatic bile acid accumulation and liver injury.
    Biochemical and biophysical research communications, 2019, 11-26, Volume: 520, Issue:1

    Topics: Angiogenic Proteins; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Liver; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Probiotics; RNA-Binding Proteins; Signal Transduction; Ursodeoxycholic Acid

2019
FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
    Journal of hepatology, 2020, Volume: 72, Issue:6

    Topics: Autophagosomes; Autophagy; Autophagy-Related Proteins; Chenodeoxycholic Acid; Cholestasis; Cytotoxins; Gene Knockdown Techniques; Hep G2 Cells; Humans; Liver; Lysosomes; Receptors, Cytoplasmic and Nuclear; Retrospective Studies; Signal Transduction; Transfection; Ursodeoxycholic Acid

2020
Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions.
    Toxicological sciences : an official journal of the Society of Toxicology, 2020, 07-01, Volume: 176, Issue:1

    Topics: Animals; Bile Acids and Salts; Biological Transport; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Drug Interactions; Hepatocytes; Humans; Ion Transport; Kinetics; Liver; Membrane Transport Proteins; Pharmaceutical Preparations; Proteomics; Taurocholic Acid

2020
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020, Volume: 1865, Issue:9

    Topics: Animals; Chenodeoxycholic Acid; Cholestasis; Hep G2 Cells; Humans; Liver; Liver Diseases; MafG Transcription Factor; Male; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Rats, Wistar; Receptors, Cytoplasmic and Nuclear

2020
Improved Markers of Cholestatic Liver Injury in Patients With Primary Biliary Cholangitis Treated With Obeticholic Acid and Bezafibrate.
    Hepatology (Baltimore, Md.), 2021, Volume: 73, Issue:6

    Topics: Alkaline Phosphatase; Bezafibrate; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Pruritus; Treatment Outcome

2021
BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination.
    JCI insight, 2020, 12-08, Volume: 6, Issue:1

    Topics: Animals; Azepines; Bile Acids and Salts; Cell Cycle Proteins; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Drug Interactions; Gene Knockdown Techniques; Humans; Liver; Liver Cirrhosis, Biliary; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Nuclear Proteins; Nuclear Receptor Co-Repressor 2; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Triazoles

2020
Primary Biliary Cholangitis: advances in management and treatment of the disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:8

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; Disease Progression; Drug Therapy, Combination; End Stage Liver Disease; Humans; Ursodeoxycholic Acid

2017
Progressive and Preferential Cellular Accumulation of Hydrophobic Bile Acids Induced by Cholestatic Drugs Is Associated with Inhibition of Their Amidation and Sulfation.
    Drug metabolism and disposition: the biological fate of chemicals, 2017, Volume: 45, Issue:12

    Topics: Amides; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Humans; Lithocholic Acid; Liver; Organic Anion Transporters, Sodium-Dependent; Sulfates; Symporters; Taurocholic Acid

2017
Obeticholic acid protects mice against lipopolysaccharide-induced liver injury and inflammation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Hepatocytes; Inflammation; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Protective Agents; Receptors, Cytoplasmic and Nuclear

2017
The pruritus of cholestasis: From bile acids to opiate agonists: Relevant after all these years.
    Medical hypotheses, 2018, Volume: 110

    Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Humans; Lysophospholipids; Models, Biological; Opioid Peptides; Pruritus; Receptors, G-Protein-Coupled; Receptors, Opioid

2018
No Gut No Gain! Enteral Bile Acid Treatment Preserves Gut Growth but Not Parenteral Nutrition-Associated Liver Injury in a Novel Extensive Short Bowel Animal Model.
    JPEN. Journal of parenteral and enteral nutrition, 2018, Volume: 42, Issue:8

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Fibroblast Growth Factors; Gastrointestinal Tract; Intestine, Small; Liver; Liver Diseases; Parenteral Nutrition; Parenteral Nutrition, Total; Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 4; Receptors, Cytoplasmic and Nuclear; Short Bowel Syndrome; Swine

2018
FXR agonist obeticholic acid induces liver growth but exacerbates biliary injury in rats with obstructive cholestasis.
    Scientific reports, 2018, 11-08, Volume: 8, Issue:1

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; cdc25 Phosphatases; Chenodeoxycholic Acid; Cholestasis; Cyclin D1; Disease Models, Animal; Fibroblast Growth Factors; Gene Expression Regulation; Liver Regeneration; Male; Organ Size; Rats

2018
Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:11

    Topics: Animals; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholestasis; Extracellular Signal-Regulated MAP Kinases; Glucose; Humans; Hydrocortisone; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Sphingosine-1-Phosphate Receptors; Steroidogenic Factor 1

2019
Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Apoptosis; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Female; Hep G2 Cells; Humans; Lithocholic Acid; Liver; Male

2013
Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2014, Volume: 46, Issue:6

    Topics: Aminoquinolines; Animals; Bile Ducts; Blood-Brain Barrier; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Disease Models, Animal; Endothelial Cells; Ligation; Male; Microvessels; Occludin; Permeability; Phosphorylation; Pyrimidines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tight Junctions; Tissue Culture Techniques; Zonula Occludens-1 Protein; Zonula Occludens-2 Protein

2014
The FXR agonist obeticholic acid prevents gut barrier dysfunction and bacterial translocation in cholestatic rats.
    The American journal of pathology, 2015, Volume: 185, Issue:2

    Topics: Animals; Bacterial Translocation; Chenodeoxycholic Acid; Cholestasis; Cytokines; Escherichia coli; Gene Expression Regulation; Ileum; Male; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear

2015
Distinct Plasma Bile Acid Profiles of Biliary Atresia and Neonatal Hepatitis Syndrome.
    Journal of proteome research, 2015, Nov-06, Volume: 14, Issue:11

    Topics: Alanine Transaminase; Area Under Curve; Aspartate Aminotransferases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biliary Atresia; Case-Control Studies; Chenodeoxycholic Acid; Cholangiography; Cholestasis; Female; gamma-Glutamyltransferase; Gene Expression Regulation; Hepatitis; Humans; Infant; Infant, Newborn; Male; Metabolome; Receptors, Cytoplasmic and Nuclear; Taurochenodeoxycholic Acid

2015
UDCA and CDCA alleviate 17α-ethinylestradiol-induced cholestasis through PKA-AMPK pathways in rats.
    Toxicology and applied pharmacology, 2016, Nov-15, Volume: 311

    Topics: Adenylate Kinase; Animals; Carrier Proteins; Cells, Cultured; Chenodeoxycholic Acid; Cholestasis; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Ethinyl Estradiol; Female; Male; Membrane Glycoproteins; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid

2016
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Adenosine Triphosphate; Animals; Bile Ducts; Caspase 3; Caspase Inhibitors; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Inflammasomes; Interleukin-1beta; Kupffer Cells; Ligation; Liver; Liver Cirrhosis; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Reactive Oxygen Species; Receptors, G-Protein-Coupled; RNA Interference; Signal Transduction; Transfection

2016
Variable clinical spectrum of the most common inborn error of bile acid metabolism--3beta-hydroxy-Delta 5-C27-steroid dehydrogenase deficiency.
    Journal of pediatric gastroenterology and nutrition, 2010, Volume: 50, Issue:1

    Topics: 3-Hydroxysteroid Dehydrogenases; Avitaminosis; Bile Acids and Salts; Chenodeoxycholic Acid; Child; Child, Preschool; Cholestasis; Cholic Acid; Female; Humans; Infant; Liver; Male; Spectrometry, Mass, Electrospray Ionization; Steatorrhea; Steroid Metabolism, Inborn Errors

2010
Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids.
    Journal of hepatology, 2010, Volume: 52, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Gene Expression; Genes, Reporter; Genetic Variation; Glucuronosyltransferase; Hep G2 Cells; Humans; Lithocholic Acid; Luciferases; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Transcriptional Activation; Ursodeoxycholic Acid; Xenobiotics

2010
Molecular genetic and bile acid profiles in two Japanese patients with 3beta-hydroxy-DELTA5-C27-steroid dehydrogenase/isomerase deficiency.
    Pediatric research, 2010, Volume: 68, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; Base Sequence; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; DNA Primers; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Japan; Liver; Male; Molecular Sequence Data; Mutation; Sequence Analysis, DNA

2010
Eicosapentaenoic acid and docosahexaenoic acid synergistically attenuate bile acid-induced hepatocellular apoptosis.
    JPEN. Journal of parenteral and enteral nutrition, 2012, Volume: 36, Issue:1

    Topics: Apoptosis; Caspase 3; Caspase 7; Chenodeoxycholic Acid; Cholestasis; Docosahexaenoic Acids; Down-Regulation; Drug Synergism; Eicosapentaenoic Acid; Hep G2 Cells; Humans; Liver; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Messenger

2012
Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Jan-15, Volume: 302, Issue:2

    Topics: Animals; Animals, Newborn; Atrophy; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Fibroblast Growth Factors; Glucagon-Like Peptides; Intestinal Mucosa; Liver Diseases; Parenteral Nutrition, Total; Swine; Treatment Outcome

2012
Two neonatal cholestasis patients with mutations in the SRD5B1 (AKR1D1) gene: diagnosis and bile acid profiles during chenodeoxycholic acid treatment.
    Journal of inherited metabolic disease, 2013, Volume: 36, Issue:3

    Topics: Asian People; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Female; Gastrointestinal Agents; Humans; Infant, Newborn; Infant, Newborn, Diseases; Liver; Male; Mutation; Oxidoreductases

2013
Selective inhibition of CYP27A1 and of chenodeoxycholic acid synthesis in cholestatic hamster liver.
    Biochimica et biophysica acta, 2002, Nov-20, Volume: 1588, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bile; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Cholestasis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cricetinae; Cytochrome P-450 CYP3A; Disease Models, Animal; Down-Regulation; Liver; Microsomes, Liver; Models, Chemical; Oxidoreductases, N-Demethylating; RNA, Messenger; Steroid 12-alpha-Hydroxylase; Steroid Hydroxylases

2002
Mitochondrially mediated synergistic cell killing by bile acids.
    Biochimica et biophysica acta, 2003, Jan-20, Volume: 1637, Issue:1

    Topics: Adenine Nucleotides; Animals; Bile Acids and Salts; Cell Survival; Chenodeoxycholic Acid; Cholestasis; Drug Synergism; Hepatocytes; Ion Channels; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Rats; Rats, Sprague-Dawley; Rhodamines; Time Factors; Ursodeoxycholic Acid

2003
Mutations in the sterol 27-hydroxylase gene (CYP27A) cause hepatitis of infancy as well as cerebrotendinous xanthomatosis.
    Journal of inherited metabolic disease, 2002, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Cholestanols; Cholestasis; Cholic Acid; DNA; Exons; Gas Chromatography-Mass Spectrometry; Hepatitis; Humans; Male; Mutation; Steroid Hydroxylases; Xanthomatosis, Cerebrotendinous

2002
Regression of diaphyseal multiloculated bone cyst in familial steroid dehydrogenase deficiency.
    Journal of pediatric gastroenterology and nutrition, 2003, Volume: 36, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Bilirubin; Bone Cysts; Chenodeoxycholic Acid; Cholestasis; Hepatomegaly; Humans; Infant; Liver Diseases; Male; Splenomegaly

2003
Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:2

    Topics: Animals; Chenodeoxycholic Acid; Cholestasis; DNA-Binding Proteins; Dose-Response Relationship, Drug; Estrogens; Hepatocytes; Ligands; Male; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2005
Nuclear receptors, bile-acid detoxification, and cholestasis.
    Lancet (London, England), 2006, Feb-11, Volume: 367, Issue:9509

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; DNA-Binding Proteins; Enzyme Inhibitors; Homeostasis; Humans; Mice; Pregnane X Receptor; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; Transcription Factors

2006
[Effects of bile acids and bilirubin on pancreatic secretion in obstructive jaundice].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1983, Volume: 80, Issue:9

    Topics: Animals; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Dogs; Insulin

1983
Management of gallstones. The new option of bile acid therapy.
    Postgraduate medicine, 1983, Volume: 74, Issue:5

    Topics: Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Humans

1983
Serum primary bile acids in chronic alcoholic pancreatitis.
    Hepato-gastroenterology, 1983, Volume: 30, Issue:5

    Topics: Alcoholism; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chronic Disease; Female; Humans; Male; Pancreatitis

1983
Serum concentrations of bile acid glucuronides in hepatobiliary diseases.
    Digestion, 1983, Volume: 27, Issue:4

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Male

1983
Glycoursodeoxycholate is as effective as tauroursodeoxycholate in preventing the taurocholate-induced cholestasis in the rat.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 42, Issue:3

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Drug Evaluation, Preclinical; Rats; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1983
Gall bladder volume and serum bile acids in cholestasis of pregnancy.
    British journal of obstetrics and gynaecology, 1982, Volume: 89, Issue:1

    Topics: Adult; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Female; Gallbladder; Humans; Pregnancy; Pregnancy Complications; Ultrasonography

1982
Tauroursodeoxycholate prevents taurocholate induced cholestasis.
    Life sciences, 1982, Feb-07, Volume: 30, Issue:6

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Kinetics; Male; Rats; Rats, Inbred WF; Taurochenodeoxycholic Acid; Taurocholic Acid

1982
[Elimination of the lithogenic properties of the bile in patients with certain forms of postcholecystectomy syndrome].
    Klinicheskaia meditsina, 1982, Volume: 60, Issue:3

    Topics: Bile; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholecystectomy; Cholelithiasis; Cholestasis; Diet; Drug Combinations; Humans; Plant Extracts; Postoperative Care; Syndrome; Terpenes; Time Factors; Tissue Extracts

1982
Analysis of bile acid glucuronides in urine: group separation on a lipophilic anion exchanger.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Aug-18, Volume: 123, Issue:3

    Topics: Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholestasis; Chromatography, Ion Exchange; Glucuronates; Glucuronidase; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Sulfates

1982
Pathologic versus physiologic cholestasis: elevated serum concentration of a secondary bile acid in the presence of hepatobiliary disease.
    The Journal of pediatrics, 1981, Volume: 98, Issue:3

    Topics: Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Humans; Infant; Infant, Newborn; Lithocholic Acid; Liver Diseases; Sulfates

1981
Bile acid assays as an index of cholestasis.
    Clinical chemistry, 1981, Volume: 27, Issue:6

    Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Clinical Laboratory Techniques; Glycocholic Acid; Male; Rats

1981
[Different effect of taurolithocholate and chenodeoxycholate on structure and function of isolated hepatocytes (author's transl)].
    Klinische Wochenschrift, 1981, Jun-15, Volume: 59, Issue:12

    Topics: Animals; Aspartate Aminotransferases; Cell Membrane; Chenodeoxycholic Acid; Cholestasis; Dose-Response Relationship, Drug; Glucagon; L-Lactate Dehydrogenase; Lithocholic Acid; Liver; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Taurolithocholic Acid; Uric Acid

1981
Urinary excretion of bile acids in cholestasis: evidence for renal tubular secretion in man.
    Clinical science (London, England : 1979), 1981, Volume: 61, Issue:6

    Topics: Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Ethacrynic Acid; Female; Furosemide; Glycocholic Acid; Humans; Kidney Tubules; Male; Metabolic Clearance Rate; Middle Aged; Probenecid

1981
Plasma bile acid levels and liver disease.
    Acta medica Academiae Scientiarum Hungaricae, 1981, Volume: 38, Issue:2

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Diagnosis, Differential; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Spectrometry, Fluorescence

1981
Biliary sludge after liver transplantation: 2. Treatment with interventional techniques versus surgery and/or oral chemolysis.
    AJR. American journal of roentgenology, 1995, Volume: 164, Issue:4

    Topics: Adolescent; Adult; Aged; Bile; Chenodeoxycholic Acid; Child; Child, Preschool; Cholestasis; Drainage; Female; Humans; Liver Transplantation; Male; Middle Aged; Palliative Care; Postoperative Complications; Reoperation; Retrospective Studies; Stents; Therapeutic Irrigation

1995
Familial giant cell hepatitis with low bile acid concentrations and increased urinary excretion of specific bile alcohols: a new inborn error of bile acid synthesis?
    Pediatric research, 1995, Volume: 37, Issue:4 Pt 1

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholestasis; Cholic Acid; Cholic Acids; Follow-Up Studies; Giant Cells; Hepatitis; Humans; Infant; Male; Metabolism, Inborn Errors; Molecular Structure

1995
Effect of cholestasis and bile acids on interferon-induced 2',5'-adenylate synthetase and NK cell activities.
    Gastroenterology, 1995, Volume: 108, Issue:4

    Topics: 2',5'-Oligoadenylate Synthetase; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Enzyme Induction; Humans; Interferon-alpha; Killer Cells, Natural; Lymphocytes; Male; Rats; Rats, Wistar; Ursodeoxycholic Acid

1995
Synthesis and metabolism of sodium 3 alpha,7 alpha-dihydroxy-25,26-bishomo-5 beta-cholane-26-sulfonate in the hamster.
    Lipids, 1995, Volume: 30, Issue:1

    Topics: Animals; Chenodeoxycholic Acid; Cholestasis; Cricetinae; Glycochenodeoxycholic Acid; Intestinal Absorption; Liver; Male; Mesocricetus; Molecular Structure

1995
Isolation of the microtubule-vesicle motor kinesin from rat liver: selective inhibition by cholestatic bile acids.
    Gastroenterology, 1995, Volume: 108, Issue:3

    Topics: Amino Acid Sequence; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Kinesins; Liver; Microtubules; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid

1995
Changes in bile acid composition of serum and gallbladder bile in bile duct ligated dogs.
    The Journal of veterinary medical science, 1994, Volume: 56, Issue:2

    Topics: Animals; Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Dogs; Gallbladder; Lithocholic Acid; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Time Factors

1994
Effects of bile acids and cholestasis on major histocompatibility complex class I in human and rat hepatocytes.
    Gastroenterology, 1994, Volume: 107, Issue:3

    Topics: Adult; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme Activation; Female; Histocompatibility Antigens Class I; Humans; Kinetics; Liver; Male; Middle Aged; Protein Kinase C; Rats; RNA, Messenger

1994
[Results of 4 years of gallstone lithotripsy].
    Nederlands tijdschrift voor geneeskunde, 1993, Apr-10, Volume: 137, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Chenodeoxycholic Acid; Cholecystectomy; Cholelithiasis; Cholestasis; Colic; Female; Humans; Lithotripsy; Male; Middle Aged; Pancreatitis; Recurrence; Retrospective Studies; Ursodeoxycholic Acid

1993
Delta 4-3-oxosteroid 5 beta-reductase deficiency: failure of ursodeoxycholic acid treatment and response to chenodeoxycholic acid plus cholic acid.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Cholic Acids; Female; Humans; Infant, Newborn; Oxidoreductases; Ursodeoxycholic Acid

1996
Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Cyclosporine; Fasting; Female; Glycocholic Acid; Heart Transplantation; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Lithocholic Acid; Male; Middle Aged; Spectrophotometry, Ultraviolet; Taurocholic Acid; Ursodeoxycholic Acid

1996
Determination of fetal bile acids in biological fluids from neonates by gas chromatography-negative ion chemical ionization mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Mar-28, Volume: 691, Issue:1

    Topics: Bile Acids and Salts; Body Fluids; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Infant, Newborn; Meconium

1997
Bile acid inhibition of interferon activity in human lymphocytes: no evidence of oxidative stress.
    European journal of clinical investigation, 1997, Volume: 27, Issue:6

    Topics: 2',5'-Oligoadenylate Synthetase; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Drug Resistance; Glutathione; Hepatitis C; Humans; In Vitro Techniques; Interferon alpha-2; Interferon-alpha; Lymphocytes; Malondialdehyde; Oxidative Stress; Recombinant Proteins

1997
Urinary 7alpha-hydroxy-3-oxochol-4-en-24-oic and 3-oxochola-4,6-dien-24-oic acids in infants with cholestasis.
    Journal of hepatology, 1998, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Biliary Atresia; Case-Control Studies; Chenodeoxycholic Acid; Child; Child, Preschool; Cholestasis; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Liver Diseases; Male; Middle Aged; Oxidoreductases

1998
Abnormally low ratio of cholic acid to chenodeoxycholic acid due to a deficiency of 3-oxo-delta4-steroid 5beta-reductase.
    Pediatrics international : official journal of the Japan Pediatric Society, 2000, Volume: 42, Issue:5

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Humans; Hypoglycemia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Oxidoreductases

2000
Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria.
    Bioscience reports, 2001, Volume: 21, Issue:1

    Topics: Animals; Calcium; Chenodeoxycholic Acid; Cholestasis; Cyclosporine; Enzyme Inhibitors; Gastrointestinal Agents; Indicators and Reagents; Liver; Male; Membrane Potentials; Mitochondria, Liver; Osmosis; Permeability; Rats; Rats, Wistar; Ruthenium Red; Subcellular Fractions

2001
Enhancement of endothelial nitric oxide production by chenodeoxycholic acids in patients with hepatobiliary diseases.
    Japanese heart journal, 2001, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Endothelium, Vascular; Female; Hemodynamics; Humans; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide; Ventricular Function, Left

2001
Reduced activity of 11 beta-hydroxysteroid dehydrogenase in patients with cholestasis.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:9

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; 11-beta-Hydroxysteroid Dehydrogenases; Active Transport, Cell Nucleus; Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholestasis; Dose-Response Relationship, Drug; Female; Fibrosis; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Kidney; Male; Microscopy, Fluorescence; Middle Aged; Models, Chemical; Potassium; Sodium; Tetrahydrocortisol; Time Factors; Transfection

2001
The UDCA dosage deficit: a fate shared with CDCA.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:3

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Dose-Response Relationship, Drug; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2002
Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor.
    The Journal of biological chemistry, 2002, Jul-19, Volume: 277, Issue:29

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Active Transport, Cell Nucleus; Animals; Bile Acids and Salts; Cells, Cultured; Chenodeoxycholic Acid; CHO Cells; Cholestasis; Cricetinae; Deoxycholic Acid; Female; Fluorescent Antibody Technique; Gallstones; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Kinetics; Male; Models, Chemical; Receptors, Mineralocorticoid; Transcriptional Activation

2002
Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2002, Volume: 50, Issue:3

    Topics: 1-Naphthylisothiocyanate; Adenine Nucleotides; Alanine Transaminase; Animals; Calcium; Cell Membrane Permeability; Chenodeoxycholic Acid; Cholestasis; Energy Metabolism; Female; Hepatocytes; Homeostasis; Injections, Intraperitoneal; Intracellular Membranes; Membrane Potentials; Mitochondria, Liver; Rats; Rats, Wistar

2002
[Adverse effects of chenodeoxycholic-acid therapy].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1976, Issue:9

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Fatty Liver; Humans

1976
[Important problem in practice: disorders of bile secretion (proceedings)].
    MMW, Munchener medizinische Wochenschrift, 1979, May-25, Volume: 121, Issue:21

    Topics: Biliary Tract; Chenodeoxycholic Acid; Cholangitis; Cholecystitis; Cholelithiasis; Cholestasis; Humans; Radiography

1979
Urinary bile acids in late pregnancy and in recurrent cholestasis of pregnancy.
    European journal of clinical investigation, 1979, Volume: 9, Issue:6

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Recurrence

1979
Fetal bile acid levels in pregnancies complicated by maternal intrahepatic cholestasis.
    American journal of obstetrics and gynecology, 1975, Aug-01, Volume: 122, Issue:7

    Topics: Androstenols; Apgar Score; Birth Weight; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetal Blood; Fetal Distress; Humans; Infant, Newborn; Labor, Induced; Pregnancy; Pregnancy Complications; Pregnanediol; Pruritus; Transaminases

1975
Bile acid metabolism in benign recurrent intrahepatic cholestasis. Comparative studies on the icteric and anicteric phases of a single case.
    Gastroenterology, 1979, Volume: 76, Issue:5 Pt 1

    Topics: Adult; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Feces; Humans; Lithocholic Acid; Male; Recurrence

1979
Fetal sulfated and nonsulfated bile acids in intrahepatic cholestasis of pregnancy.
    The Journal of laboratory and clinical medicine, 1978, Volume: 92, Issue:2

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Chromatography, Gas; Female; Fetal Blood; Fetus; Mass Spectrometry; Pregnancy; Pregnancy Complications

1978
[Surgical, endoscopical and medical treatment of gallstones (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1978, Volume: 35, Issue:9

    Topics: Calcium; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholangitis; Cholecystectomy; Cholecystitis; Cholelithiasis; Cholestasis; Cholesterol; Deoxycholic Acid; Humans

1978
Effect of cholestyramine and phenobarbital on pruritus and serum bile acid levels in cholestasis of pregnancy.
    American journal of obstetrics and gynecology, 1978, Nov-01, Volume: 132, Issue:5

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholestyramine Resin; Cholic Acids; Female; Humans; Phenobarbital; Pregnancy; Pregnancy Complications; Pruritus

1978
Postprandial serum bile acids in cholestasis of pregnancy.
    Annals of clinical research, 1978, Volume: 10, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Fasting; Female; Humans; Pregnancy; Pregnancy Complications

1978
Clinical significance of serum bile acid measurement in liver diseases.
    Gastroenterologia Japonica, 1978, Volume: 13, Issue:6

    Topics: Acute Disease; Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases

1978
Radioimmunoassay of conjugated cholic acid, chenodeoxycholic acid, and deoxycholic acid from human serum, with use of 125I-labeled ligands.
    Clinical chemistry, 1979, Volume: 25, Issue:2

    Topics: Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Pregnancy; Pregnancy Complications; Radioimmunoassay

1979
Serum bile acids in cholestasis of pregnancy.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:3

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Female; Fetal Distress; Humans; Infant, Newborn; Liver Function Tests; Placenta; Pregnancy; Pregnancy Complications; Pruritus

1977
Elevations in skin tissue levels of bile acids in human cholestasis: relation to serum levels and topruritus.
    Gastroenterology, 1977, Volume: 73, Issue:5

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Female; Humans; Lithocholic Acid; Male; Middle Aged; Pruritus; Skin

1977
Levels of immunoreactive glycine-conjugated bile acids in health and hepatobiliary disease.
    American journal of clinical pathology, 1976, Volume: 66, Issue:5

    Topics: Alcoholism; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Glycocholic Acid; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Radioimmunoassay

1976
Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis.
    Gut, 1976, Volume: 17, Issue:11

    Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Humans; Liver Cirrhosis; Sulfates

1976
Sulfated and nonsulfated bile acids in urine, serum, and bile of patients with hepatobiliary diseases.
    Gastroenterology, 1975, Volume: 68, Issue:3

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Male; Sulfates

1975
Phenobarbital effects in cholestatic liver diseases.
    Annals of internal medicine, 1975, Volume: 82, Issue:3

    Topics: Adult; Bile Ducts, Intrahepatic; Bilirubin; Chenodeoxycholic Acid; Child; Child, Preschool; Cholangitis; Cholestasis; Cholic Acids; Feces; Female; Hepatitis; Humans; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Phenobarbital; Pruritus; Rose Bengal; Sulfobromophthalein

1975
Medical treatment of gallstones.
    Southern medical journal, 1975, Volume: 68, Issue:1

    Topics: Animals; Arteriosclerosis; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholesterol; Diarrhea; Humans; Lipid Metabolism; Lithocholic Acid; Liver; Macaca mulatta; Phenobarbital; Phosphatidylcholines; Placebos

1975
Determination of serum bile acids by glass capillary gas-liquid chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Oct-01, Volume: 64, Issue:1

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Female; Gestational Age; Humans; Pregnancy; Pregnancy Complications

1975
Synthetic capacity and cell metabolites of bile duct obstructed rat livers. Effect of free and conjugated dihydroxy bile acids.
    Acta hepato-gastroenterologica, 1975, Volume: 22, Issue:5

    Topics: Acetoacetates; Adenine Nucleotides; Animals; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Common Bile Duct; Deoxycholic Acid; Female; Gluconeogenesis; Glycogen; Hydroxybutyrates; Ketone Bodies; Ligation; Liver; Male; Rats; Urea

1975
[Physiology of bile secretion].
    Acta medica Austriaca, 1975, Volume: 2, Issue:3

    Topics: Amiloride; Animals; Bile; Bile Acids and Salts; Biological Transport, Active; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholesterol; Ethinyl Estradiol; Humans; Liver; Liver Circulation; Phospholipids; Rabbits; Rats; Sodium; Solubility

1975
Bile acid glucuronides, II[1]. Isolation and identification of a chenodeoxycholic acid glucuronide from human plasma in intrahepatic cholestasis.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1976, Volume: 357, Issue:2

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Glucuronates; Mass Spectrometry

1976
[Dissolution of cholesterol calculi using chenodeoxycholic acid].
    Deutsche medizinische Wochenschrift (1946), 1976, Jul-23, Volume: 101, Issue:30

    Topics: Alcoholism; Chenodeoxycholic Acid; Cholecystitis; Cholelithiasis; Cholestasis; Cholesterol; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis

1976
[Ursotherapy in hepatobiliary diseases].
    Acta gastroenterologica Latinoamericana, 1992, Volume: 22, Issue:3

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Humans; Liver Diseases; Ursodeoxycholic Acid

1992
Bile acid N-acetylglucosaminidation. In vivo and in vitro evidence for a selective conjugation reaction of 7 beta-hydroxylated bile acids in humans.
    The Journal of clinical investigation, 1992, Volume: 89, Issue:6

    Topics: Acetylglucosamine; Administration, Oral; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Glycosides; Humans; Hydroxylation; Liver Diseases; Mass Spectrometry; Ursodeoxycholic Acid

1992
Synthesis of 13C-labeled chenodeoxycholic, hyodeoxycholic, and ursodeoxycholic acids for the study of bile acid metabolism in liver disease.
    Clinica chimica acta; international journal of clinical chemistry, 1991, Nov-09, Volume: 203, Issue:1

    Topics: Administration, Oral; Carbon Isotopes; Chenodeoxycholic Acid; Cholestasis; Chromatography, Thin Layer; Deoxycholic Acid; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Spectrophotometry, Infrared; Ursodeoxycholic Acid

1991
Abnormal low ratio of cholic acid to chenodeoxycholic acid in a cholestatic infant with severe hypoglycemia.
    Journal of pediatric gastroenterology and nutrition, 1991, Volume: 12, Issue:3

    Topics: Adult; Bile; Bile Duct Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Enterohepatic Circulation; Female; Humans; Hypoglycemia; Infant, Newborn; Male

1991
Formation of biliary thrombi in protoporphyrin-induced cholestasis in perfused rat liver.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Diseases; Microscopy, Electron; Perfusion; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1990
Tauroursodeoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liver.
    Journal of hepatology, 1990, Volume: 10, Issue:3

    Topics: Animals; Chenodeoxycholic Acid; Cholestasis; Lithocholic Acid; Liver; Rats; Taurochenodeoxycholic Acid; Taurolithocholic Acid

1990
Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat.
    The American journal of physiology, 1985, Volume: 248, Issue:4 Pt 1

    Topics: 5'-Nucleotidase; Albumins; Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Isomerism; L-Lactate Dehydrogenase; Male; Nucleotidases; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Time Factors

1985
Prevention of endotoxaemia in obstructive jaundice--a comparative study of bile salts.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1988, Volume: 1, Issue:1

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Deoxycholic Acid; Endotoxins; Escherichia coli; Glycodeoxycholic Acid; Intestinal Absorption; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Taurodeoxycholic Acid; Ursodeoxycholic Acid

1988
[Occurrence of urinary 3 beta,7 alpha- and 3 beta,7 beta-dihydroxy-5-cholenoic acids in cholestasis].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1988, Volume: 85, Issue:9

    Topics: Chenodeoxycholic Acid; Cholestasis; Humans

1988
Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha-dihydroxy-and 3 beta,7 alpha, 12 alpha-trihydroxy-5-cholenoic acids.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Chenodeoxycholic Acid; Cholenes; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, Ion Exchange; Gas Chromatography-Mass Spectrometry; Hepatitis; Humans; Infant, Newborn; Male; Spectrophotometry, Atomic

1987
Bile acid excretion after disappearance of jaundice in intrahepatic cholestasis of infancy.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:3

    Topics: Autoradiography; Bile Acids and Salts; Bilirubin; Carbon Isotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Chromatography, Thin Layer; Creatinine; Cytomegalovirus; Humans; Infant; Transaminases; Trypsin Inhibitors

1973
Formation and excretion of bile salt sulfates: an important metabolic pathway in cholestasis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: Suppl 4

    Topics: Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Child, Preschool; Cholestasis; Cholic Acids; Female; Humans; Liver; Sulfuric Acids; Tritium

1974
Pruritic effect of bile salts.
    British medical journal, 1974, Dec-21, Volume: 4, Issue:5946

    Topics: Adolescent; Adult; Aged; Bile Acids and Salts; Blister; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Female; Humans; Male; Middle Aged; Pruritus; Skin Tests

1974
Sulfated and nonsulfated bile acid in human serum.
    Lipids, 1972, Volume: 7, Issue:11

    Topics: Adult; Aged; Bile Acids and Salts; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gel; Chromatography, Ion Exchange; Deoxycholic Acid; Female; Glycocholic Acid; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Sulfuric Acids; Taurocholic Acid

1972
Cholestatic syndromes in infancy: diagnostic value of serum bile acid pattern and cholestyramine administration.
    Pediatric research, 1973, Volume: 7, Issue:3

    Topics: Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Child, Preschool; Cholestasis; Cholestyramine Resin; Cholic Acids; Chromatography, Gas; Diagnosis, Differential; Female; Humans; Infant; Infant, Newborn; Male; Nucleotidases

1973
Excretion of bile acids in extrahepatic biliary atresia and intrahepatic cholestasis of infancy.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:3

    Topics: Autoradiography; Bile Acids and Salts; Bile Ducts; Carbon Isotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Chromatography, Thin Layer; Complement Fixation Tests; Constriction; Creatinine; Diagnosis, Differential; Female; Half-Life; Humans; Infant; Infant, Newborn; Liver Cirrhosis, Biliary; Male; Transaminases; Trypsin Inhibitors

1973
Effects of phenobarbital on bile salt metabolism in cholestasis due to intrahepatic bile duct hypoplasia.
    Pediatrics, 1973, Volume: 51, Issue:6

    Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; Bilirubin; Carbon Isotopes; Chenodeoxycholic Acid; Child, Preschool; Cholestasis; Cholic Acids; Feces; Female; Half-Life; Humans; Leucyl Aminopeptidase; Liver; Phenobarbital; Pruritus

1973
Biliary excretion of bile acids, lecithin, and cholesterol in hamsters with gallstones.
    Gastroenterology, 1973, Volume: 65, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholesterol; Chromatography; Cricetinae; Deficiency Diseases; Diet; Fatty Acids; Glycocholic Acid; Linoleic Acids; Male; Phosphatidylcholines; Secretory Rate

1973
Excretion of bile acids in erythroblastosis foetalis.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:2

    Topics: Autoradiography; Bile Acids and Salts; Bilirubin; Carbon Isotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Chromatography, Thin Layer; Erythroblastosis, Fetal; Feces; Female; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Male; Pregnancy; Time Factors

1973
Clinical aspects of alterations in bile acid metabolism--the wrong bile acids in the wrong place.
    Scottish medical journal, 1973, Volume: 18, Issue:5

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Celiac Disease; Chenodeoxycholic Acid; Cholestasis; Colonic Diseases; Diarrhea; Hepatitis A; Ileum; Intestinal Mucosa; Intestine, Small; Lithocholic Acid; Liver Cirrhosis; Malabsorption Syndromes; Neomycin; Pancreatitis; Pruritus; Zollinger-Ellison Syndrome

1973
[Bile acids in the serum of patients with extrahepatic cholestasis with chronic liver diseases].
    Zeitschrift fur Gastroenterologie, 1973, Volume: 11, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chronic Disease; Deoxycholic Acid; Hepatic Encephalopathy; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases

1973
[Formation of bile acid sulfate esters in perfused rat livers following bile duct occlusion].
    Zeitschrift fur Gastroenterologie, 1974, Volume: 12, Issue:2

    Topics: Animals; Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Esters; Lithocholic Acid; Liver; Male; Perfusion; Rats; Sulfates; Taurocholic Acid

1974