Page last updated: 2024-08-21

chenodeoxycholic acid and Chemical and Drug Induced Liver Injury

chenodeoxycholic acid has been researched along with Chemical and Drug Induced Liver Injury in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199029 (52.73)18.7374
1990's3 (5.45)18.2507
2000's2 (3.64)29.6817
2010's18 (32.73)24.3611
2020's3 (5.45)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ali, B; Eaton, JE; Kamath, PS; Reddy, R; Sathapathy, S; Vuppalanchi, R1
Beaudoin, JJ; Bezençon, J; Brouwer, KLR; Fallon, JK; Sjöstedt, N1
Gao, L; Guo, S; Li, J; Li, Y; Liu, H; Liu, M; Ru, H; Shu, Z; Sun, DD; Tan, Q; Xie, R; Zang, Y; Zhou, Y1
Cui, Y; Li, R; Ren, Y; Wang, C; Xiong, X; Zhang, Y1
Aschenbrenner, DS1
Ashby, K; Borlak, J; Chen, M; Mehta, R; Navarro Almario, EE; Tong, W1
Rockey, DC1
Oda, S; Takeuchi, T; Tsuneyama, K; Yang, F; Yokoi, T1
Afonso, SG; Batlle, A; Buzaleh, AM; Martinez, Mdel C; Meiss, R; Ruspini, SF1
Bosch, AM; Huidekoper, HH; Vaz, FM; Verrips, A1
Cai, W; Chen, Y; Gong, Z; Tian, C; Wang, P; Wu, J; Xu, C; Zhao, S; Zhou, J1
Bridges, AS; Brouwer, KL; Corbett, AH; Kashuba, AD; McRae, M; Rezk, NL; Tien, HC1
Brouwer, KL; Marion, TL; Perry, CH; St Claire, RL; Yue, W1
Cipriani, S; D'Amore, C; Distrutti, E; Fiorucci, S; Mencarelli, A; Migliorati, M; Renga, B1
Chen, J; Chen, M; Lian, F; Liang, L; Wang, Y; Xu, H; Yang, X; Ye, Y; Zhan, Z1
Alvarez, AR; Amigo, L; Ferrada, C; Galdames, L; Klein, A; Miquel, JF; Morales, MG; Quinones, V; Rigotti, A; Rio, MC; Tichauer, JE; Zanlungo, S1
Fukunari, A; Imada, T; Ishizaki, K; Iwaki, T; Kinoshita, S; Tanaka, H; Tsurufuji, M1
Aitio, A; Härkönen, H; Lehtniemi, A1
Tangedahl, TN1
Mogadam, M1
Lachin, JM; Schoenfield, LJ1
Buffet, C; Chaput, JC; Etienne, JP; Franco, D; Houssin, D; Labayle, D1
Carey, MC; Palmer, RH1
Barbara, L; Bazzoli, F; Fromm, H; Roda, A; Roda, E; Sarva, RP1
Hanson, RF1
Baker, D; Gochman, N; Javitt, NB; Jones, HM; Miyai, K1
Forkman, A; Tobiasson, P1
Fujiwara, K; Matsui, A; Nagoshi, S; Ohta, Y1
Chen, T; Dyrszka, H; Mosbach, EH; Salen, G; Saltzman, WH1
Brunner, H; Grabner, G; Horak, W1
Leuschner, U1
Bouma, ME; Darnis, F; Infante, R; Lageron, A; Levy, VG1
Bonorris, GG; Marks, JW; Pearlman, BJ; Schoenfield, LJ1
Paumgartner, G; Weber, M1
Ingelfinger, FJ1
Standaert, LO1
Allan, RN; Gadacz, TR; Hofmann, AF; Mack, E1
Glenn, F; May, PS; McSherry, CK; Morrissey, KP; Niemann, WH; Swarm, RL1
Goldstein, LI; Schoenfield, LJ1
Deitrick, JE; McSherry, CK; Morrissey, KP; Nieman, WH; Swarm, RL1
Andersen, RB; Bruusgaard, A1
Doishita, K; Kitagawa, T; Nonomura, A; Ota, G1
Berenson, MM; Garcia-Marin, JJ; Welch, V1
Berenson, MM; Bjorkman, DJ; Gunther, C; Samowitz, WS1
Alvaro, D; Angelico, M; Attili, AF; Cantafora, A; Capocaccia, L1
Dowling, RH1
Cooper, NS; Fischer, CD; Mosbach, EH; Rothschild, MA1
Lahana, DA; Schoenfield, LJ1
Schoenfield, LJ1

Reviews

9 review(s) available for chenodeoxycholic acid and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Review article: therapeutic bile acids and the risks for hepatotoxicity.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:12

    Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Humans; Liver

2018
Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety.
    Annals of internal medicine, 1981, Volume: 95, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Diarrhea; Double-Blind Method; Drug Evaluation; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Random Allocation; Sex Factors; Time Factors

1981
Gallstone dissolution--a progress report.
    Clinics in gastroenterology, 1979, Volume: 8, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Contraceptives, Oral, Synthetic; Deoxycholic Acid; Diarrhea; Enterohepatic Circulation; Estrogens; Female; Gallstones; Humans; Liver; Male; Phosphatidylcholines; Pregnancy; Recurrence; Risk

1979
[Current status of treatment of gall stones with chenodeoxycholic acid].
    Tijdschrift voor gastro-enterologie, 1975, Volume: 18, Issue:1

    Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cricetinae; Diarrhea; Digestive System; Dogs; Haplorhini; Humans; Liver; Liver Cirrhosis; Macaca mulatta; Mice; Rabbits; Rats

1975
Gallstones: pathogenesis and medical treatment.
    Advances in internal medicine, 1975, Volume: 20

    Topics: Adult; Animals; Arizona; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Fasting; Female; Guinea Pigs; Humans; Indians, North American; Liver; Male; Middle Aged; Minnesota; Phosphatidylcholines

1975
The goose that laid the golden bile: gallstone dissolution in man with chenodeoxycholic acid.
    Irish journal of medical science, 1974, Volume: 0, Issue:0

    Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholecystectomy; Cholelithiasis; Cholesterol; Cholic Acids; Diarrhea; Dogs; Female; Haplorhini; Humans; Lipid Metabolism; Macaca; Male; Radiography; Rats; Solubility

1974
Progress in medical therapy of gallstones.
    The Surgical clinics of North America, 1973, Volume: 53, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Humans

1973
Medical therapy for gallstones.
    Gastroenterology, 1974, Volume: 67, Issue:4

    Topics: Administration, Oral; Bile; Bile Acids and Salts; Bilirubin; Calcium; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Humans; Lithocholic Acid; Liver; Phenobarbital; United States

1974

Trials

3 trial(s) available for chenodeoxycholic acid and Chemical and Drug Induced Liver Injury

ArticleYear
Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety.
    Annals of internal medicine, 1981, Volume: 95, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Diarrhea; Double-Blind Method; Drug Evaluation; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Random Allocation; Sex Factors; Time Factors

1981
Sounding Board. An optimistic view of the National Cooperative Gallstone Study.
    The New England journal of medicine, 1982, May-13, Volume: 306, Issue:19

    Topics: Bile; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Clinical Trials as Topic; Diarrhea; Humans; Liver; Recurrence; Triglycerides

1982
Hepatic sinusoidal dilatation after chenodeoxycholic-acid therapy.
    Lancet (London, England), 1978, Jan-28, Volume: 1, Issue:8057

    Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Clinical Trials as Topic; Dilatation, Pathologic; Follow-Up Studies; Humans

1978

Other Studies

44 other study(ies) available for chenodeoxycholic acid and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Liver Injury in Patients With Cholestatic Liver Disease Treated With Obeticholic Acid.
    Hepatology (Baltimore, Md.), 2020, Volume: 71, Issue:4

    Topics: Aged; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged

2020
Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions.
    Toxicological sciences : an official journal of the Society of Toxicology, 2020, 07-01, Volume: 176, Issue:1

    Topics: Animals; Bile Acids and Salts; Biological Transport; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Drug Interactions; Hepatocytes; Humans; Ion Transport; Kinetics; Liver; Membrane Transport Proteins; Pharmaceutical Preparations; Proteomics; Taurocholic Acid

2020
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis.
    Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21

    Topics: Animals; Binding Sites; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Drug Design; Drug Evaluation, Preclinical; Half-Life; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship

2020
Obeticholic acid protects mice against lipopolysaccharide-induced liver injury and inflammation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Hepatocytes; Inflammation; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Protective Agents; Receptors, Cytoplasmic and Nuclear

2017
Excessive Dosing of Obeticholic Acid May Increase Risk of Liver Damage.
    The American journal of nursing, 2018, Volume: 118, Issue:2

    Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholangitis; Dose-Response Relationship, Drug; Gastrointestinal Agents; Humans; United States; United States Food and Drug Administration

2018
Editorial: Advances in Hepatology: 2019.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Antiviral Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; End Stage Liver Disease; Gastroenterology; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Non-alcoholic Fatty Liver Disease; Palliative Care

2019
Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2019, 07-01, Volume: 170, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Disease Models, Animal; Drug Synergism; Female; Ketoconazole; Liver; Liver Function Tests; Rats, Sprague-Dawley

2019
Experimental protoporphyria: effect of bile acids on liver damage induced by griseofulvin.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Dehydrocholic Acid; Deoxycholic Acid; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Griseofulvin; Humans; Lipid Peroxidation; Mice; Oxidative Stress; Porphyrins; Protoporphyria, Erythropoietic; Superoxide Dismutase; Ursodeoxycholic Acid

2015
Hepatotoxicity due to chenodeoxycholic acid supplementation in an infant with cerebrotendinous xanthomatosis: implications for treatment.
    European journal of pediatrics, 2016, Volume: 175, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Child, Preschool; Encephalitis, Viral; Female; Humans; Infant, Newborn; Neonatal Screening; Parechovirus; Picornaviridae Infections; Xanthomatosis, Cerebrotendinous

2016
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Adenosine Triphosphate; Animals; Bile Ducts; Caspase 3; Caspase Inhibitors; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Inflammasomes; Interleukin-1beta; Kupffer Cells; Ligation; Liver; Liver Cirrhosis; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Reactive Oxygen Species; Receptors, G-Protein-Coupled; RNA Interference; Signal Transduction; Transfection

2016
Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.
    Pharmacotherapy, 2010, Volume: 30, Issue:1

    Topics: Adult; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Early Diagnosis; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lithocholic Acid; Liver; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Tandem Mass Spectrometry; Taurocholic Acid; Time Factors

2010
Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 120, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Chromans; Chromatography, High Pressure Liquid; Hepatocytes; Male; PPAR gamma; Propionates; Quinolines; Rats; Rats, Wistar; Tandem Mass Spectrometry; Taurocholic Acid; Thiazolidinediones; Troglitazone

2011
SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:6

    Topics: Animals; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Gene Expression Regulation; HEK293 Cells; Hepatic Stellate Cells; Humans; Interleukin-1beta; Male; Myofibroblasts; Phenotype; PPAR gamma; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Tumor Necrosis Factor-alpha

2011
Activation of farnesoid X receptor attenuates liver injury in systemic lupus erythematosus.
    Rheumatology international, 2012, Volume: 32, Issue:6

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Case-Control Studies; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Concanavalin A; Cytoprotection; Disease Models, Animal; Female; Humans; Inflammation Mediators; Interferon-gamma; Interleukin-6; Liver; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha

2012
Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.
    World journal of gastroenterology, 2007, Jun-14, Volume: 13, Issue:22

    Topics: Adenoviridae; Alkaline Phosphatase; Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Disease Models, Animal; Gene Expression Regulation; Humans; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Phenotype; Phosphoproteins; Transfection

2007
Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters.
    World journal of gastroenterology, 2007, Oct-07, Volume: 13, Issue:37

    Topics: Alanine Transaminase; Animals; Bile Acids and Salts; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cricetinae; Eating; Liver; Liver Diseases; Mesocricetus; Ursodeoxycholic Acid

2007
Styrene exposure and the liver.
    Scandinavian journal of work, environment & health, 1984, Volume: 10, Issue:1

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholic Acids; Female; Follow-Up Studies; gamma-Glutamyltransferase; Humans; Liver; Middle Aged; Occupational Diseases; Polystyrenes; Prospective Studies; Styrenes; Time Factors

1984
Management of gallstones. The new option of bile acid therapy.
    Postgraduate medicine, 1983, Volume: 74, Issue:5

    Topics: Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Humans

1983
The GI drug column. The ACG committee on FDA related matters.
    The American journal of gastroenterology, 1983, Volume: 78, Issue:3

    Topics: Alginates; Aluminum Hydroxide; Antacids; Bicarbonates; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cimetidine; Dicyclomine; Drug Combinations; Gastrointestinal Diseases; Humans; Magnesium Hydroxide; Silicic Acid; Simethicone; Sodium Bicarbonate; United States; United States Food and Drug Administration

1983
[Hepatology in 1981].
    La Revue du praticien, 1981, Dec-21, Volume: 31, Issue:59

    Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Liver Transplantation; Peliosis Hepatis; Peritoneovenous Shunt; Ursodeoxycholic Acid

1981
Relationship between serum and biliary bile acids as an indicator of chenodeoxycholic and ursodeoxycholic acid-induced hepatotoxicity in the rhesus monkey.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:5

    Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Deoxycholic Acid; Female; Lithocholic Acid; Macaca mulatta; Male; Sulfates; Ursodeoxycholic Acid

1982
Gallstones--the case for medical management.
    Geriatrics, 1982, Volume: 37, Issue:7

    Topics: Aged; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholecystectomy; Cholecystitis; Cholelithiasis; Dietary Fats; Female; Gallstones; Humans; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid

1982
Hepatotoxicity of bile acids in rabbits: ursodeoxycholic acid is less toxic than chenodeoxycholic acid.
    Laboratory investigation; a journal of technical methods and pathology, 1982, Volume: 46, Issue:4

    Topics: Animals; Bile Canaliculi; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cytoskeleton; Deoxycholic Acid; Lithocholic Acid; Liver; Liver Diseases; Prognosis; Rabbits; Ursodeoxycholic Acid

1982
Serum bile acids in acute hepatitis.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholic Acids; Hepatitis, Viral, Human; Humans; Middle Aged; Radioimmunoassay

1981
Protective action of putrescine against rat liver injury.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:2

    Topics: Administration, Oral; Animals; Carbon Tetrachloride Poisoning; Cell Membrane; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Galactosamine; Lipid Peroxidation; Liver; Liver Diseases; Male; Octoxynol; Peroxides; Putrescine; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide

1994
Letter Prevention of chenodeoxycholic-acid toxicity with lincomycin.
    Lancet (London, England), 1975, May-10, Volume: 1, Issue:7915

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Drug Antagonism; Lincomycin; Liver; Liver Diseases; Macaca mulatta

1975
[Adverse effects of chenodeoxycholic-acid therapy].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1976, Issue:9

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Fatty Liver; Humans

1976
[Liver damage during treatment with cheno-acid: animal experiment results and findings in patients with cheno-acid therapy].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1976, Issue:9

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cricetinae; Haplorhini; Humans; Macaca mulatta; Mice; Mitochondria, Liver; Rabbits; Rats

1976
[Surgical, endoscopical and medical treatment of gallstones (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1978, Volume: 35, Issue:9

    Topics: Calcium; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholangitis; Cholecystectomy; Cholecystitis; Cholelithiasis; Cholestasis; Cholesterol; Deoxycholic Acid; Humans

1978
Editorial: Testing drugs: men, mice and baboons.
    The New England journal of medicine, 1975, Sep-04, Volume: 293, Issue:10

    Topics: Animals; Blood Coagulation; Blood Platelets; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Drug Evaluation; Haplorhini; Humans; Mice; Papio; Platelet Aggregation; Rabbits; Somatostatin

1975
Impaired lithocholate sulfation in the rhesus monkey: a possible mechanism for chenodeoxycholate toxicity.
    Gastroenterology, 1976, Volume: 70, Issue:6

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholic Acids; Female; Haplorhini; Humans; Kinetics; Lithocholic Acid; Macaca mulatta; Species Specificity; Sulfuric Acids

1976
Chenodeoxycholic acid induced liver injury in pregnant and neonatal baboons.
    Annals of surgery, 1976, Volume: 184, Issue:4

    Topics: Animals; Animals, Newborn; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Female; Gallbladder; Haplorhini; Liver; Papio; Pregnancy; Pregnancy Complications

1976
Toxicity of chenodeoxycholic acid in the nonhuman primate.
    Surgery, 1975, Volume: 77, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Biopsy; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholesterol; Female; Lithocholic Acid; Liver; Papio; Pregnancy

1975
Effect of an intravenously administered bile acid (chenodeoxycholic acid) on rheumatoid arthritis.
    Scandinavian journal of rheumatology, 1975, Volume: 4, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Drug Evaluation; Female; Hematocrit; Humans; Injections, Intravenous; Male; Middle Aged; Time Factors

1975
[An autopsy case of hepatitis probably induced by chenodeoxycholic acid and thiamphenicol author's transl].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1975, Volume: 72, Issue:1

    Topics: Anti-Bacterial Agents; Autopsy; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Female; Humans; Liver; Middle Aged; Thiamphenicol

1975
Importance of bile acid structure in amelioration of griseofulvin-induced murine protoporphyric hepatopathy.
    The Journal of laboratory and clinical medicine, 1991, Volume: 118, Issue:1

    Topics: Absorption; Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis, Intrahepatic; Cholic Acid; Cholic Acids; Female; Griseofulvin; Liver; Liver Diseases; Mice; Protoporphyrins; Structure-Activity Relationship; Ursodeoxycholic Acid

1991
Formation of biliary thrombi in protoporphyrin-induced cholestasis in perfused rat liver.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Diseases; Microscopy, Electron; Perfusion; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1990
Bile acid-induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids.
    Medical hypotheses, 1986, Volume: 19, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Biotransformation; Cell Membrane; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Detergents; gamma-Glutamyltransferase; Humans; Macaca mulatta; Papio; Rabbits; Taurine

1986
Effect of dietary chenodeoxycholic acid and lithocholic acid in the rabbit.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:10

    Topics: Animals; Appetite; Bile; Bile Acids and Salts; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Deoxycholic Acid; Diet; Lithocholic Acid; Liver; Liver Cirrhosis; Male; Rabbits

1974