Page last updated: 2024-08-21

chenodeoxycholic acid and Biliary Cirrhosis

chenodeoxycholic acid has been researched along with Biliary Cirrhosis in 104 studies

Research

Studies (104)

TimeframeStudies, this research(%)All Research%
pre-199011 (10.58)18.7374
1990's12 (11.54)18.2507
2000's2 (1.92)29.6817
2010's50 (48.08)24.3611
2020's29 (27.88)2.80

Authors

AuthorsStudies
Abenavoli, L; Alvaro, D; Bertino, G; Brunetto, M; Calvaruso, V; Cannavò, M; Carbone, M; Cazzagon, N; Chessa, L; Claar, E; Coco, B; Colapietro, F; Cotugno, R; Cozzolongo, R; Cristoferi, L; Cuccorese, G; D'Amato, D; D'Antò, M; De Gasperi, E; De Vincentis, A; Distefano, M; Fiorini, C; Floreani, A; Frazzetto, E; Galati, G; Galli, A; Gerussi, A; Giannini, EG; Invernizzi, P; Izzi, A; Labanca, S; Lleo, A; Losito, F; Malinverno, F; Marconi, G; Marra, F; Marzioni, M; Morelli, O; Morgando, A; Mulinacci, G; Muratori, L; Niro, GA; Palermo, A; Palitti, VP; Pellicano, R; Pellicelli, A; Picardi, A; Pompili, M; Ponziani, F; Ronca, V; Rosina, F; Russello, M; Sacco, R; Saitta, C; Scaravaglio, M; Scifo, G; Simone, L; Storato, S; Terracciani, F; Tortora, A; Vanni, E; Vespasiani-Gentilucci, U; Viganò, M; Zolfino, T; Zuin, M1
Adekunle, F; Battezzati, PM; Bowlus, CL; Bruns, T; Carbone, M; Cazzagon, N; Corpechot, C; Dalekos, GN; Fisher, H; Flack, S; Floreani, A; Gatselis, NK; Gulamhusein, A; Hansen, BE; Hirschfield, GM; Hiu, S; Invernizzi, P; Janssen, HLA; Jones, D; Kareithi, D; Kowdley, KV; Lammers, WJ; Lindor, KD; Lleo, A; Londoño, MC; Malecha, E; Mason, AL; Mayne, T; Mayo, MJ; Mells, G; Mulcahy, V; Murillo Perez, CF; Ness, E; Nevens, F; Parés, A; Smith, R; Thorburn, D; Trauner, M; Trivedi, PJ; van der Meer, AJ; Verhelst, X; Wason, J1
Díaz-González, Á; Londoño, MC1
Buchanan-Peart, KA; Levy, C1
Adams, D; Alpini, G; Banales, JM; Beuers, U; Björnsson, E; Bowlus, C; Carbone, M; Chazouillères, O; Dalekos, G; De Gottardi, A; Gershwin, ME; Harada, K; Hirschfield, G; Invernizzi, P; Jones, D; Krawitt, E; Lanzavecchia, A; Lian, ZX; Ma, X; Manns, M; Mavilio, D; Mieli-Vergani, G; Quigley, EM; Sallusto, F; Shimoda, S; Strazzabosco, M; Swain, M; Tanaka, A; Terziroli Beretta-Piccoli, B; Trauner, M; Tsuneyama, K; Vergani, D; Vierling, JM; Zigmond, E1
Bedossa, P; Bowlus, CL; Drenth, JPH; Forman, LM; Iloeje, U; Jin, Y; Kremer, AE; Liberman, A; MacConell, L; Parés, A; Pencek, R; Pockros, PJ; Ryder, SD; Terracciano, L1
Ali, B; Eaton, JE; Kamath, PS; Reddy, R; Sathapathy, S; Vuppalanchi, R1
Bowlus, C; Gao, L; Gershwin, ME; He, X; Leung, PSC; Wang, L; Woo, E; Yang, G1
Kowdley, KV; Shah, RA1
Gulamhusein, AF; Hirschfield, GM1
Gulamhusein, AF; Hansen, BE1
Chascsa, DMH; Lindor, KD1
Hirschfield, G; Invernizzi, P; Liberman, A; MacConell, L; Malecha, ES; Parés, A; Shiffman, M; Vargas, V1
Andreone, P; Bowlus, CL; Floreani, A; Goldberg, D; Hirschfield, GM; Jin, Y; Kowdley, KV; LaRusso, NF; Levy, C; MacConell, L; Pencek, R; Rushbrook, S; Schiano, T; Shapiro, D; Shrestha, R; Trotter, J; Vuppalanchi, R1
Dyson, JK; Jones, D; Phaw, NA1
Chapman, RW; Lynch, KD1
de Veer, RC; Laschtowitz, A; Schramm, C; Van der Meer, AJ1
Ahn, DW1
Castro Limo, JD; Romero-Gutiérrez, M; Ruiz Martín, J1
Chai, J; Li, Q; Li, X; Liao, M; Pan, Q; Peng, Y; Qu, J; Xie, Q; Yang, H1
Majee, C; Mishra, R; Sahu, R1
Erickson, M; Frisch, K; Hofmann, AF; Horsager, J; Keiding, S; Kjærgaard, K; Munk, OL; Schacht, AC; Shapiro, D; Sørensen, M1
Korf, H; Nevens, F; Smets, L; van der Merwe, S; Verbeek, J1
Chen, J; Chen, LF; Chiang, CM; Hu, X; Jung, H; Kemper, B; Kemper, JK; Sun, H; Wu, SY1
Ampuero, J; Arenas, JI; Berenguer, M; Carrión, JA; Casado, M; Conde, I; Costa-Moreira, P; De Carvalho, A; Fernández-Rodríguez, CM; Garcia Buey, L; Gomez, E; Hernández-Guerra, M; Jorquera, F; Luisa Gutiérrez, M; Macedo, G; Manuel Sousa, J; Mesquita, M; Molina, E; Morillas, RM; Olveira, A; Pérez-Fernández, E; Presa, J; Santos, A; Simón, MA; Uriz, J1
Gao, Y; Li, B; Li, L; Zhan, Y1
Arab, JP; Candia, R; Kulkarni, AV; Kumar, P; Padaki, NR; Premkumar, M; Reddy, DN; Sharma, M; Tevethia, HV1
Alric, L; Anty, R; Berg, T; Bureau, C; Carbone, M; Carrat, F; Cazzagon, N; Cervoni, JP; Chazouillères, O; Corpechot, C; Dumortier, J; Heurgué, A; Invernizzi, P; Lam, L; Larrey, D; Leroy, V; Levy, C; Nevens, F; Pares, A; Potier, P; Rosa-Hezode, I; Roux, O; Schramm, C; Silvain, C; Smets, L; Soret, PA; Trivedi, P; Weiler-Normann, C1
Dyson, JK; Jones, DEJ; Wetten, A1
Albillos, A; Álvarez-Navascués, C; Andrade, RJ; Arencibia, A; Berenguer, M; Casado, M; Chahri, N; De la Cruz, G; Diago, M; Estevez, P; Fábrega, E; Fernandez-Bonilla, E; Fernández-Rodriguez, CM; Ferre-Aracil, C; Gallego-Moya, A; Gómez-Camarero, J; Gómez-Domínguez, E; González-Santiago, JM; Hernández-Guerra, M; Hijona, L; Horta, D; Molina, E; Morillas, RM; Parés, A; Pérez-Medrano, IM; Reig, A; Romero-Gomez, M; Sala, M; Suárez, F; Vargas, V; Vergara, M1
Bowlus, C; Floreani, A; Gershwin, ME; Tanaka, A1
Gershwin, ME; Tanaka, A1
Carbone, M; Invernizzi, P1
Carey, EJ; Chascsa, D; Lindor, KD1
Hegade, VS; Jones, DEJ; Wong, LL1
Floreani, A; Mangini, C1
Lindor, KD; Silveira, MG2
Bernuzzi, F; Carbone, M; Gershwin, ME; Invernizzi, P; Malinverno, F; Mousa, HS; Ronca, V1
Adorini, L; Beecher-Jones, T; Böhm, O; Chapman, R; Hirschfield, GM; Jones, D; Kowdley, KV; Luketic, V; Marschall, HU; Mason, A; Parés, A; Pencek, R; Poupon, R; Rust, C; Schramm, C; Sciacca, C; Shapiro, D; Vincent, C1
Strassburg, CP1
Levy, C1
Bossen, L; Grønbæk, H; Hamberg, O; Jepsen, P; Ott, P; Ytting, H1
Alexander, GJM; Chapman, MH; Collier, J; Dyson, JK; Hirschfield, GM; Hübscher, S; Jones, DEJ; Patanwala, I; Pereira, SP; Thain, C; Thorburn, D; Tiniakos, D; Walmsley, M; Webster, G1
Corrigan, M; Jones, D; Jopson, L; Khanna, A; Peterson, P; Rudell, E1
Goldstein, J; Levy, C1
Bonetto, S; Durazzo, M; Fagoonee, S; Morgando, A; Pellicano, R1
Bahar, R; Bowlus, CL; Liu, CH; Wong, KA1
Hirschfield, GM; Webb, GJ2
Corrigan, M; Hegade, VS; Hirschfield, GM; Holmes, E; Jones, DE; Kendrick, S; Marchesi, JR; McDonald, JAK; Pechlivanis, A; Rees, D; Taylor-Robinson, SD1
Kowdley, KV; Manne, V1
Rockey, DC1
Eaton, JE; Gores, GJ1
Corpechot, C1
Carbone, M; Cristoferi, L; Gerussi, A; Invernizzi, P; Ronca, V1
Lindor, KD; Momah, N1
Bowlus, CL; Cazzagon, N; Floreani, A; Franceschet, I; Gershwin, ME; Perini, L1
Adorini, L; Beecher-Jones, T; Bodhenheimer, HC; Böhm, O; Castelloe, E; Gordon, SC; Hirschfield, GM; Kowdley, KV; Lindor, K; Luketic, V; Marschall, HU; Mason, A; Mayo, M; Parés, A; Sciacca, C; Shapiro, D; Trauner, M; Vincent, C1
Bowlus, CL; Gershwin, ME; Invernizzi, P; Lleo, A; Mousa, HS1
Neuschwander-Tetri, BA1
Vetter, C1
Hirschfield, GM1
Chen, G; Dong, R; Zheng, S1
Gershwin, ME; Hirschfield, GM; Trivedi, PJ1
Czul, F; Levy, C1
Parés, A2
Wang, L; Zhang, FC; Zhang, X1
Keam, SJ; Markham, A1
Ali, AH; Lindor, KD1
Andreone, P; Beuers, U; Bowlus, C; Drenth, JP; Floreani, A; Hansen, B; Hirschfield, GM; Hohenester, S; Hooshmand-Rad, R; Invernizzi, P; Jones, DE; Kowdley, KV; Lindor, KD; Luketic, V; MacConell, L; Marmon, T; Marschall, HU; Mazzella, G; Nevens, F; Pencek, R; Pockros, PJ; Pruzanski, M; Regula, J; Shah, H; Shapiro, D; Sheeron, S; Shiffman, M; Strasser, SI; Trauner, M; van Erpecum, KJ; Vargas, V; Vincent, C1
Thomas, H1
Alawad, AS; Levy, C1
Erlinger, S1
Beuers, U; de Vries, E1
Li, B; Ma, X; Wang, QX1
Lindor, KD1
Matsui, A; Setchell, KD1
Aly, A; Carlson, K; Johansson, C; Kirstein, P; Rössner, S; Wallentin, L1
Aly, A; Johansson, C; Norman, A; Samuelson, K1
Fehér, T; Loi, HG; Magyar, I1
Hirano, F; Makino, I; Tanaka, H1
Chrétien, Y; Paumgartner, G; Poupon, R; Poupon, RE1
Aldini, R; Bazzoli, F; Cipolla, A; Festi, D; Mazzella, G; Parini, P; Polimeni, C; Roda, A; Tonelli, D; Villanova, N1
Moriwaki, H; Muto, Y; Nishigaki, Y; Ohnishi, H1
Azer, SA; Byth, K; Coverdale, SA; Farrell, GC; Stacey, NH1
Kaneko, S; Kobayashi, K; Ogino, H; Saeki, R; Unoura, M1
Bateson, MC1
Salemans, JM; Tangerman, A; Van Berge-Henegouwen, GP; van Buuren, HR; van de Meeberg, PC; van Erpecum, KJ; van Hattum, J; Wolfhagen, FH1
Batta, AK; DeSotel, CK; Dickson, ER; Hofmann, AF; Jorgensen, RA; Lacerda, MA; Lindor, KD; Rossi, SS; Salen, G1
Bonner, GF; Boyer, JL; Carithers, RL; Combes, B; Garcia-Tsao, G; Hofmann, AF; Luketic, VA; Maddrey, WC; Munoz, S; Peters, MG; Risser, R; Rossi, SS; Shiffman, ML; White, H; Zetterman, RK1
Fukawa, E; Hirano, F; Hirano, Y; Kobayashi, A; Makino, I; Nomura, Y1
Azzaroli, F; Ferrara, F; Festi, D; Giovanelli, S; Liva, S; Mazzella, G; Nigro, G; Roda, E1
MacDonald, IA; Park-Dincsoy, H; Williams, CN1
Bloomer, JR; Boyer, JL1
Allen, RM; Bloomer, JR; Klatskin, G1
Stiefelhagen, P1
Doty, JE; Tompkins, RK1
Kocsár, LT; Orbán, EC; Pallos, JP1
Fehér, T; Kazik, MH; Papp, J1
Norman, A; Strandvik, B1

Reviews

44 review(s) available for chenodeoxycholic acid and Biliary Cirrhosis

ArticleYear
Novel Therapies in Primary Biliary Cholangitis: What Is in the Pipeline?
    Clinics in liver disease, 2022, Volume: 26, Issue:4

    Topics: Chenodeoxycholic Acid; Cholangitis; Humans; Liver Cirrhosis, Biliary; Quality of Life; Ursodeoxycholic Acid

2022
The challenges of primary biliary cholangitis: What is new and what needs to be done.
    Journal of autoimmunity, 2019, Volume: 105

    Topics: Antibodies, Antinuclear; Autoimmune Diseases; Chenodeoxycholic Acid; Cholagogues and Choleretics; Congresses as Topic; Female; Humans; Liver; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2019
Clinical Management of Primary Biliary Cholangitis-Strategies and Evolving Trends.
    Clinical reviews in allergy & immunology, 2020, Volume: 59, Issue:2

    Topics: Animals; Bile Acids and Salts; Biomarkers; Chenodeoxycholic Acid; Combined Modality Therapy; Disease Management; Disease Progression; Disease Susceptibility; Fibrosis; Humans; Immunotherapy; Liver Cirrhosis, Biliary; Liver Transplantation; Molecular Targeted Therapy; Severity of Illness Index; Symptom Assessment; Treatment Outcome; Ursodeoxycholic Acid

2020
Current and potential treatments for primary biliary cholangitis.
    The lancet. Gastroenterology & hepatology, 2020, Volume: 5, Issue:3

    Topics: Benzothiazoles; Bezafibrate; Bile Acids and Salts; Budesonide; Case-Control Studies; Chenodeoxycholic Acid; Cholagogues and Choleretics; Clinical Trials as Topic; Cyclosporine; Disease Progression; Glucocorticoids; Homeostasis; Humans; Immunologic Factors; Immunosuppressive Agents; Isoxazoles; Liver Cirrhosis, Biliary; Liver Transplantation; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Rituximab; Treatment Outcome; United States; United States Food and Drug Administration; Ursodeoxycholic Acid

2020
Primary biliary cholangitis: pathogenesis and therapeutic opportunities.
    Nature reviews. Gastroenterology & hepatology, 2020, Volume: 17, Issue:2

    Topics: Adaptive Immunity; Animals; Autoimmunity; Bile Acids and Salts; Chenodeoxycholic Acid; Chloride-Bicarbonate Antiporters; Cholagogues and Choleretics; Dihydrolipoyllysine-Residue Acetyltransferase; Disease Progression; Environmental Exposure; Epigenesis, Genetic; Humans; Immunity, Innate; Liver Cirrhosis; Liver Cirrhosis, Biliary; MicroRNAs; Organic Anion Transporters, Sodium-Dependent; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Symporters; Ursodeoxycholic Acid

2020
Emerging therapies for PBC.
    Journal of gastroenterology, 2020, Volume: 55, Issue:3

    Topics: Chenodeoxycholic Acid; Disease Progression; End Stage Liver Disease; Female; Fibric Acids; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Middle Aged; Ursodeoxycholic Acid

2020
Emerging drugs for the treatment of primary biliary cholangitis.
    Expert opinion on emerging drugs, 2020, Volume: 25, Issue:2

    Topics: Animals; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Progression; Drug Development; Humans; Liver Cirrhosis, Biliary; Quality of Life; Ursodeoxycholic Acid

2020
Obeticholic acid-a new therapy in PBC and NASH.
    British medical bulletin, 2020, 05-15, Volume: 133, Issue:1

    Topics: Chenodeoxycholic Acid; Gastrointestinal Agents; Humans; Liver Cirrhosis, Biliary; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2020
Diagnosis and treatment of primary biliary cholangitis.
    United European gastroenterology journal, 2020, Volume: 8, Issue:6

    Topics: Autoantigens; Autoimmune Diseases; Bezafibrate; Biomarkers; Biopsy; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Progression; Drug Therapy, Combination; Elasticity Imaging Techniques; End Stage Liver Disease; Fatigue; Female; Humans; Immunoglobulin M; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Liver Transplantation; Middle Aged; Off-Label Use; Prognosis; Pruritus; Quality of Life; Severity of Illness Index; Sjogren's Syndrome; Survival Rate; Treatment Outcome; Ursodeoxycholic Acid

2020
[Novel Insights of Primary Sclerosing Cholangitis and Primary Biliary Cholangitis].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2020, 05-25, Volume: 75, Issue:5

    Topics: Alkaline Phosphatase; Chenodeoxycholic Acid; Cholangitis, Sclerosing; Humans; Liver Cirrhosis, Biliary; Prognosis; Risk Factors; Ursodeoxycholic Acid

2020
Combination therapy of obeticholic acid and ursodeoxycholic acid in patients with primary biliary cholangitis who respond incompletely to ursodeoxycholic acid: a systematic review.
    European journal of gastroenterology & hepatology, 2020, Volume: 32, Issue:9

    Topics: Alanine Transaminase; Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2020
An insight into primary biliary cholangitis and its recent advances in treatment: semi-synthetic analogs to combat ursodeoxycholic-acid resistance.
    Expert review of gastroenterology & hepatology, 2020, Volume: 14, Issue:10

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acids; Humans; Liver Cirrhosis, Biliary; Nitrates; Ursodeoxycholic Acid

2020
Response Rate and Impact on Lipid Profiles of Obeticholic Acid Treatment for Patients with Primary Biliary Cholangitis: A Meta-Analysis.
    Canadian journal of gastroenterology & hepatology, 2021, Volume: 2021

    Topics: Chenodeoxycholic Acid; Humans; Lipids; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2021
Efficacy and safety of obeticholic acid in liver disease-A systematic review and meta-analysis.
    Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:3

    Topics: Chenodeoxycholic Acid; Cholestasis; Humans; Liver Cirrhosis, Biliary; Non-alcoholic Fatty Liver Disease; Pharmaceutical Preparations; Ursodeoxycholic Acid

2021
Geoepidemiology and changing mortality in primary biliary cholangitis.
    Journal of gastroenterology, 2017, Volume: 52, Issue:6

    Topics: Animals; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Models, Animal; Drug Design; Fluorescent Antibody Technique, Indirect; Humans; Liver Cirrhosis, Biliary; Precision Medicine; Ursodeoxycholic Acid

2017
Old and new treatments for primary biliary cholangitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:4

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; End Stage Liver Disease; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2017
What Comes after Ursodeoxycholic Acid in Primary Biliary Cholangitis?
    Digestive diseases (Basel, Switzerland), 2017, Volume: 35, Issue:4

    Topics: Chenodeoxycholic Acid; Cholangitis; Disease Progression; Humans; Liver Cirrhosis, Biliary; Quality of Life; Ursodeoxycholic Acid

2017
Primary biliary cholangitis: Old and novel therapy.
    European journal of internal medicine, 2018, Volume: 47

    Topics: Budesonide; Chenodeoxycholic Acid; Disease Progression; End Stage Liver Disease; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2018
Investigational drugs in phase II clinical trials for primary biliary cholangitis.
    Expert opinion on investigational drugs, 2017, Volume: 26, Issue:10

    Topics: Animals; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Disease Progression; Drug Design; Drugs, Investigational; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2017
From pathogenesis to novel therapies in the treatment of primary biliary cholangitis.
    Expert review of clinical immunology, 2017, Volume: 13, Issue:12

    Topics: Autoimmunity; Bile Ducts, Intrahepatic; Chenodeoxycholic Acid; Cholangitis; Fibrosis; Humans; Immunotherapy; Liver; Liver Cirrhosis, Biliary; Molecular Targeted Therapy; Ursodeoxycholic Acid; Ustekinumab

2017
[Modern treatment of primary biliary cholangitis].
    Der Internist, 2018, Volume: 59, Issue:1

    Topics: Bezafibrate; Budesonide; Chenodeoxycholic Acid; Cohort Studies; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Multicenter Studies as Topic; PPAR alpha; Pregnancy; Prognosis; Quality of Life; Receptors, Cytoplasmic and Nuclear; Risk Assessment; Treatment Outcome; Ursodeoxycholic Acid

2018
[New name and new treatments for primary biliary cholangitits].
    Ugeskrift for laeger, 2018, Mar-05, Volume: 180, Issue:10

    Topics: Anti-Inflammatory Agents; Budesonide; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Fibric Acids; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2018
Novel and emerging therapies for cholestatic liver diseases.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:9

    Topics: Bile Acids and Salts; Budesonide; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Drug Therapy, Combination; Elasticity Imaging Techniques; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2018
Current Treatment Options for Primary Biliary Cholangitis.
    Clinics in liver disease, 2018, Volume: 22, Issue:3

    Topics: Alkaline Phosphatase; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Comorbidity; Drug Therapy, Combination; Fenofibrate; Fibroblast Growth Factors; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Malnutrition; Osteoporosis; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2018
Work in Progress: Drugs in Development.
    Clinics in liver disease, 2018, Volume: 22, Issue:3

    Topics: Abatacept; Acetates; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Bezafibrate; CD40 Antigens; CD40 Ligand; Chalcones; Chemokine CX3CL1; Chenodeoxycholic Acid; Cholic Acids; Drug Development; Fenofibrate; Fibroblast Growth Factors; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Janus Kinase Inhibitors; Liver Cirrhosis, Biliary; Methylamines; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Propionates; Pruritus; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Thiazepines; Triazoles; Ustekinumab

2018
Obeticholic acid in primary biliary cholangitis: where we stand.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Chenodeoxycholic Acid; Cholesterol, HDL; Dose-Response Relationship, Drug; Drug Labeling; Dyslipidemias; Humans; Liver Cirrhosis, Biliary; Nasopharyngitis; Pruritus; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2019
Precision medicine in primary biliary cholangitis.
    Journal of digestive diseases, 2019, Volume: 20, Issue:7

    Topics: Chenodeoxycholic Acid; Disease Progression; Gastrointestinal Agents; Humans; Liver Cirrhosis, Biliary; Precision Medicine

2019
Obeticholic acid and budesonide for the treatment of primary biliary cirrhosis.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:3

    Topics: Bile Acids and Salts; Budesonide; Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid

2014
Primary biliary cirrhosis in adults.
    Expert review of gastroenterology & hepatology, 2014, Volume: 8, Issue:4

    Topics: Adult; Autoimmune Diseases; Chenodeoxycholic Acid; Cholagogues and Choleretics; Humans; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2014
New therapies for primary biliary cirrhosis.
    Clinical reviews in allergy & immunology, 2015, Volume: 48, Issue:2-3

    Topics: Biological Factors; Budesonide; Chenodeoxycholic Acid; Clinical Trials as Topic; Fibric Acids; Humans; Liver Cirrhosis, Biliary; Treatment Outcome

2015
Advances in pharmacotherapy for primary biliary cirrhosis.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:5

    Topics: Autoimmune Diseases; Bile Acids and Salts; Budesonide; Chenodeoxycholic Acid; End Stage Liver Disease; Female; Fibric Acids; Humans; Liver; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Treatment Failure; Ursodeoxycholic Acid

2015
Obeticholic acid for the treatment of primary biliary cirrhosis.
    Expert review of clinical pharmacology, 2016, Volume: 9, Issue:1

    Topics: Animals; Chenodeoxycholic Acid; Dose-Response Relationship, Drug; End Stage Liver Disease; Humans; Liver Cirrhosis, Biliary; Pruritus; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2016
Novel Therapies on Primary Biliary Cirrhosis.
    Clinics in liver disease, 2016, Volume: 20, Issue:1

    Topics: Abatacept; Anti-Retroviral Agents; Antibodies, Monoclonal, Humanized; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Fenofibrate; Glucocorticoids; Humans; Hypolipidemic Agents; Immunologic Factors; Liver Cirrhosis, Biliary; Mesenchymal Stem Cell Transplantation; Receptors, Cytoplasmic and Nuclear; Rituximab; Ursodeoxycholic Acid; Ustekinumab

2016
Therapeutic advances for primary biliary cholangitis: the old and the new.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:6

    Topics: Abatacept; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cyclosporine; Enzyme Inhibitors; Fibric Acids; Glucocorticoids; Humans; Immunosuppressive Agents; Indoles; Liver Cirrhosis, Biliary; Mesenchymal Stem Cell Transplantation; Methotrexate; Mycophenolic Acid; Pyridones; Rituximab; Tacrolimus; Ursodeoxycholic Acid; Ustekinumab

2016
Obeticholic Acid: First Global Approval.
    Drugs, 2016, Volume: 76, Issue:12

    Topics: Chenodeoxycholic Acid; Drug Approval; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2016
Obeticholic acid for the treatment of primary biliary cholangitis.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:13

    Topics: Animals; Autoimmune Diseases; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; End Stage Liver Disease; Genome-Wide Association Study; Humans; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2016
FXR Agonists: From Bench to Bedside, a Guide for Clinicians.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Animals; Azepines; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Drug Evaluation, Preclinical; Gastrointestinal Agents; Hepatitis, Autoimmune; Humans; Hypertension, Portal; Indoles; Isoxazoles; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Biliary; Liver Diseases; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2016
Management of cholestatic disease in 2017.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37 Suppl 1

    Topics: Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis, Sclerosing; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2017
Primary biliary cholangitis in 2016: High-definition PBC: biology, models and therapeutic advances.
    Nature reviews. Gastroenterology & hepatology, 2017, Volume: 14, Issue:2

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary

2017
Novel Treatment Strategies for Primary Biliary Cholangitis.
    Seminars in liver disease, 2017, Volume: 37, Issue:1

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Disease Progression; Fibric Acids; Gastrointestinal Agents; Humans; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2017
[Research advances in autoimmune liver diseases in 2016].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2017, Feb-20, Volume: 25, Issue:2

    Topics: Autoimmune Diseases; Biomedical Research; Chenodeoxycholic Acid; Cholangitis; Cholangitis, Sclerosing; Clinical Trials, Phase III as Topic; Hepatitis, Autoimmune; Humans; Liver Cirrhosis, Biliary; Liver Diseases

2017
Farnesoid X receptor agonists for primary biliary cirrhosis.
    Current opinion in gastroenterology, 2011, Volume: 27, Issue:3

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Gastrointestinal Agents; Humans; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear

2011
Serum bile acid analysis.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Jan-07, Volume: 127, Issue:1

    Topics: Adult; Aged; Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Child; Child, Preschool; Cholic Acids; Chromatography, Gas; Chromatography, Gel; Deoxycholic Acid; Female; Gas Chromatography-Mass Spectrometry; Humans; Ileum; Lithocholic Acid; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged

1983
Modern management of biliary tract stone disease.
    Advances in surgery, 1987, Volume: 20

    Topics: Chenodeoxycholic Acid; Cholecystectomy; Cholecystitis; Cholelithiasis; Humans; Lithotripsy; Liver Cirrhosis, Biliary; Solvents; Ursodeoxycholic Acid

1987

Trials

13 trial(s) available for chenodeoxycholic acid and Biliary Cirrhosis

ArticleYear
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
    Gastroenterology, 2022, Volume: 163, Issue:6

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022
Long-Term Obeticholic Acid Therapy Improves Histological Endpoints in Patients With Primary Biliary Cholangitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2020, Volume: 18, Issue:5

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Ursodeoxycholic Acid

2020
Reduction and stabilization of bilirubin with obeticholic acid treatment in patients with primary biliary cholangitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2020, Volume: 40, Issue:5

    Topics: Bilirubin; Chenodeoxycholic Acid; Cholangitis; Humans; Liver Cirrhosis, Biliary; Liver Function Tests

2020
A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis.
    Journal of hepatology, 2020, Volume: 73, Issue:1

    Topics: Alkaline Phosphatase; Chenodeoxycholic Acid; Cholagogues and Choleretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Female; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Pruritus; Treatment Outcome

2020
Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis.
    Journal of hepatology, 2021, Volume: 74, Issue:1

    Topics: Aged; Alkaline Phosphatase; Bile Acids and Salts; Bile Ducts, Intrahepatic; Biological Transport; Chenodeoxycholic Acid; Double-Blind Method; Female; Gastrointestinal Agents; Hepatocytes; Humans; Liver Cirrhosis, Biliary; Middle Aged; Positron-Emission Tomography; Receptors, Cytoplasmic and Nuclear; Treatment Outcome; Ursodeoxycholic Acid

2021
A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:5

    Topics: Adult; Alkaline Phosphatase; Chenodeoxycholic Acid; Cholestasis; Double-Blind Method; Female; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2018
Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid.
    Gastroenterology, 2015, Volume: 148, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Chenodeoxycholic Acid; Cholagogues and Choleretics; Dose-Response Relationship, Drug; Double-Blind Method; Female; gamma-Glutamyltransferase; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Pruritus; Treatment Failure; Treatment Outcome; Ursodeoxycholic Acid

2015
A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.
    The New England journal of medicine, 2016, Aug-18, Volume: 375, Issue:7

    Topics: Adult; Aged; Alkaline Phosphatase; Bile Acids and Salts; Bone Density; Chenodeoxycholic Acid; Double-Blind Method; Female; Fibroblast Growth Factors; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Middle Aged; Pruritus

2016
Serum bile acids in primary biliary cirrhosis: effect of ursodeoxycholic acid therapy.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Deoxycholic Acid; Female; Humans; Lithocholic Acid; Liver Cirrhosis, Biliary; Male; Middle Aged; Placebos; Ursodeoxycholic Acid

1993
Sequential changes in serum levels of individual bile acids in patients with chronic cholestatic liver disease.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:3

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholangitis, Sclerosing; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged; Predictive Value of Tests; Prognosis; Survival Rate

1996
Single or multiple dose ursodeoxycholic acid for cholestatic liver disease: biliary enrichment and biochemical response.
    Journal of hepatology, 1996, Volume: 25, Issue:6

    Topics: Adult; Alkaline Phosphatase; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis, Sclerosing; Chromatography, Gas; Cross-Over Studies; Deoxycholic Acid; Dose-Response Relationship, Drug; Female; Follow-Up Studies; gamma-Glutamyltransferase; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Regression Analysis; Transaminases; Treatment Outcome; Ursodeoxycholic Acid

1996
Relationship between biliary and serum bile acids and response to ursodeoxycholic acid in patients with primary biliary cirrhosis.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:9

    Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acids; Double-Blind Method; Humans; Liver Cirrhosis, Biliary; Patient Compliance; Ursodeoxycholic Acid

1998
Biliary bile acids in primary biliary cirrhosis: effect of ursodeoxycholic acid.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:6

    Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Chromatography, Gas; Chromatography, High Pressure Liquid; Deoxycholic Acid; Double-Blind Method; Drug Administration Schedule; Female; Humans; Lithocholic Acid; Liver Cirrhosis, Biliary; Male; Middle Aged; Placebos; Regression Analysis; Reproducibility of Results; Time Factors; Ursodeoxycholic Acid

1999

Other Studies

47 other study(ies) available for chenodeoxycholic acid and Biliary Cirrhosis

ArticleYear
Predictors of serious adverse events and non-response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid.
    Liver international : official journal of the International Association for the Study of the Liver, 2022, Volume: 42, Issue:11

    Topics: Albumins; Ascites; Bilirubin; Chenodeoxycholic Acid; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male

2022
Predicting liver-related serious adverse events in patients with primary biliary cholangitis-related cirrhosis treated with obeticholic acid.
    Liver international : official journal of the International Association for the Study of the Liver, 2022, Volume: 42, Issue:11

    Topics: Chenodeoxycholic Acid; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022
Liver Injury in Patients With Cholestatic Liver Disease Treated With Obeticholic Acid.
    Hepatology (Baltimore, Md.), 2020, Volume: 71, Issue:4

    Topics: Aged; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged

2020
Beyond Biochemical Responses, Use of Histologic Staging to Predict Outcomes of Patients With Primary Biliary Cholangitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2020, Volume: 18, Issue:5

    Topics: Chenodeoxycholic Acid; Cholangitis; Humans; Liver Cirrhosis, Biliary

2020
Effective treatment of autoimmune hepatitis-primary biliary cholangitis overlap syndrome with obeticholic acid.
    Revista espanola de enfermedades digestivas, 2020, Volume: 112, Issue:9

    Topics: Adult; Chenodeoxycholic Acid; Female; Hepatitis, Autoimmune; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2020
Improved Markers of Cholestatic Liver Injury in Patients With Primary Biliary Cholangitis Treated With Obeticholic Acid and Bezafibrate.
    Hepatology (Baltimore, Md.), 2021, Volume: 73, Issue:6

    Topics: Alkaline Phosphatase; Bezafibrate; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Pruritus; Treatment Outcome

2021
BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination.
    JCI insight, 2020, 12-08, Volume: 6, Issue:1

    Topics: Animals; Azepines; Bile Acids and Salts; Cell Cycle Proteins; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Drug Interactions; Gene Knockdown Techniques; Humans; Liver; Liver Cirrhosis, Biliary; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Nuclear Proteins; Nuclear Receptor Co-Repressor 2; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Triazoles

2020
Effectiveness and safety of obeticholic acid in a Southern European multicentre cohort of patients with primary biliary cholangitis and suboptimal response to ursodeoxycholic acid.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:4

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Humans; Liver Cirrhosis, Biliary; Prospective Studies; Spain; Ursodeoxycholic Acid

2021
Combination of fibrates with obeticholic acid is able to normalise biochemical liver tests in patients with difficult-to-treat primary biliary cholangitis.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:10

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Fibric Acids; Humans; Liver Cirrhosis, Biliary; Retrospective Studies; Ursodeoxycholic Acid

2021
Specific considerations for the management of primary biliary cholangitis: are the drug treatment options good enough?
    Expert opinion on pharmacotherapy, 2021, Volume: 22, Issue:15

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Humans; Liver Cirrhosis, Biliary; Pharmaceutical Preparations; Ursodeoxycholic Acid

2021
Obeticholic Acid and Fibrates in Primary Biliary Cholangitis: Comparative Effects in a Multicentric Observational Study.
    The American journal of gastroenterology, 2021, 11-01, Volume: 116, Issue:11

    Topics: Bezafibrate; Chenodeoxycholic Acid; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Retrospective Studies; Treatment Outcome

2021
Obeticholic acid (Ocaliva) for primary biliary cholangitis.
    The Medical letter on drugs and therapeutics, 2017, 03-27, Volume: 59, Issue:1517

    Topics: Chenodeoxycholic Acid; Cholangitis; Gastrointestinal Agents; Humans; Liver; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2017
Finding the cure for primary biliary cholangitis - Still waiting.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:4

    Topics: Biomarkers; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Progression; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2017
Treatment of PBC-A step forward.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:4

    Topics: Biomarkers; Chenodeoxycholic Acid; Disease Progression; Humans; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic

2017
Evolving role of obeticholic acid in primary biliary cholangitis.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:5

    Topics: Chenodeoxycholic Acid; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2018
The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines.
    Gut, 2018, Volume: 67, Issue:9

    Topics: Alanine Transaminase; Alkaline Phosphatase; Autoantibodies; Bilirubin; Biomarkers; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Disease Progression; Gastroenterology; Humans; Liver Cirrhosis, Biliary; Mitochondria; Predictive Value of Tests; Risk Assessment; Risk Factors; Sensitivity and Specificity; Societies, Medical; Treatment Outcome; United Kingdom; Ursodeoxycholic Acid

2018
Are Clinicians Ready for Safe Use of Stratified Therapy in Primary Biliary Cholangitis (PBC)? A Study of Educational Awareness.
    Digestive diseases and sciences, 2018, Volume: 63, Issue:10

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Clinical Competence; Disease Progression; Early Diagnosis; Gastroenterologists; Humans; Liver Cirrhosis, Biliary; Risk Factors; Ursodeoxycholic Acid

2018
Management of primary biliary cholangitis prior to obeticholic acid availability.
    Minerva medica, 2018, Volume: 109, Issue:6

    Topics: Aged; Chenodeoxycholic Acid; Cholagogues and Choleretics; Female; Humans; Liver Cirrhosis, Biliary; Male; Ursodeoxycholic Acid

2018
Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:5

    Topics: Adult; Aged; Bile Acids and Salts; Biomarkers; Carrier Proteins; Case-Control Studies; Chenodeoxycholic Acid; Cholic Acid; Chromatography, Liquid; Feces; Female; Humans; Liver Cirrhosis, Biliary; Male; Membrane Glycoproteins; Methylamines; Middle Aged; Phosphoric Diester Hydrolases; Pruritus; RNA, Ribosomal, 16S; Tandem Mass Spectrometry; Thiazepines

2019
Editorial: Advances in Hepatology: 2019.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Antiviral Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; End Stage Liver Disease; Gastroenterology; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Non-alcoholic Fatty Liver Disease; Palliative Care

2019
Long-term outcomes with obeticholic acid in primary biliary cholangitis: reassuring, but still an itch we need to scratch.
    The lancet. Gastroenterology & hepatology, 2019, Volume: 4, Issue:6

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Pruritus; Ursodeoxycholic Acid

2019
Clinical Trials in PBC Going Forward.
    Seminars in liver disease, 2019, Volume: 39, Issue:3

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2019
Targeting the FXR nuclear receptor to treat liver disease.
    Gastroenterology, 2015, Volume: 148, Issue:4

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Female; Humans; Liver Cirrhosis, Biliary; Male

2015
[In Process Citation].
    MMW Fortschritte der Medizin, 2015, Volume: 157 Suppl 2

    Topics: Chenodeoxycholic Acid; Cholangitis, Sclerosing; Hope; Humans; Life Expectancy; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2015
Reply: To PMID 25500425.
    Gastroenterology, 2015, Volume: 149, Issue:2

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Female; Humans; Liver Cirrhosis, Biliary; Male

2015
The Appropriate Timing and Dose of Obeticholic Acid in Patients With Primary Biliary Cirrhosis.
    Gastroenterology, 2015, Volume: 149, Issue:2

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Female; Humans; Liver Cirrhosis, Biliary; Male

2015
Therapy of Primary Biliary Cirrhosis: Novel Approaches for Patients with Suboptimal Response to Ursodeoxycholic Acid.
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33 Suppl 2

    Topics: Antibodies, Monoclonal; Chenodeoxycholic Acid; Cholagogues and Choleretics; Fibric Acids; Glucocorticoids; Humans; Liver Cirrhosis, Biliary; Treatment Failure; Treatment Outcome; Ursodeoxycholic Acid

2015
Therapy: Obeticholic acid for PBC.
    Nature reviews. Gastroenterology & hepatology, 2016, Volume: 13, Issue:10

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2016
Obeticholic acid in primary biliary cholangitis.
    Clinics and research in hepatology and gastroenterology, 2017, Volume: 41, Issue:1

    Topics: Chenodeoxycholic Acid; Cholangitis; Double-Blind Method; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2017
Lipoprotein abnormalities in patients with early primary biliary cirrhosis.
    European journal of clinical investigation, 1984, Volume: 14, Issue:2

    Topics: Adult; Aged; Chenodeoxycholic Acid; Electrophoresis, Agar Gel; Fat Emulsions, Intravenous; Female; Humans; Lipase; Lipoproteins; Lipoproteins, HDL; Liver Cirrhosis, Biliary; Liver Function Tests; Middle Aged; Phosphatidylcholine-Sterol O-Acyltransferase

1984
Serum and urinary bile acids in patients with primary biliary cirrhosis.
    Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:1

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Radioimmunoassay

1982
Plasma bile acid levels and liver disease.
    Acta medica Academiae Scientiarum Hungaricae, 1981, Volume: 38, Issue:2

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Diagnosis, Differential; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Spectrometry, Fluorescence

1981
Chenodeoxycholic acid-dependent induction of major histocompatibility complex class I mRNA expression in a human hepatoma cell line.
    Biochemical and biophysical research communications, 1993, Sep-30, Volume: 195, Issue:3

    Topics: Carcinoma, Hepatocellular; Chenodeoxycholic Acid; Gene Expression Regulation, Neoplastic; Genes, MHC Class I; Liver Cirrhosis, Biliary; Liver Neoplasms; RNA, Messenger; Tumor Cells, Cultured

1993
Ursodeoxycholic acid administration on bile acid metabolism in patients with early stages of primary biliary cirrhosis.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:5

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Deoxycholic Acid; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Ursodeoxycholic Acid

1993
Ursodeoxycholic acid corrects defective natural killer activity by inhibiting prostaglandin E2 production in primary biliary cirrhosis.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:7

    Topics: Adult; Aged; Cells, Cultured; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chronic Disease; Deoxycholic Acid; Dinoprostone; Female; Hepatitis C; Humans; Indomethacin; Killer Cells, Natural; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged; Ursodeoxycholic Acid

1996
Effects of chenodeoxycholic and ursodeoxycholic acids on interferon-gamma production by peripheral blood mononuclear cells from patients with primary biliary cirrhosis.
    Journal of gastroenterology, 1995, Volume: 30, Issue:6

    Topics: Case-Control Studies; Cells, Cultured; Chenodeoxycholic Acid; Cholagogues and Choleretics; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Humans; In Vitro Techniques; Interferon-gamma; Leukocytes, Mononuclear; Liver Cirrhosis, Biliary; Male; Middle Aged; Ursodeoxycholic Acid

1995
Bile acid research and applications.
    Lancet (London, England), 1997, Jan-04, Volume: 349, Issue:9044

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis, Intrahepatic; Female; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Pregnancy; Pregnancy Complications; Research; Ursodeoxycholic Acid

1997
Bile acids regulate RANTES gene expression through its cognate NF-kappaB binding sites.
    Biochemical and biophysical research communications, 2001, Nov-16, Volume: 288, Issue:5

    Topics: Antibodies; Bile Acids and Salts; Binding Sites; Chemokine CCL5; Chenodeoxycholic Acid; Electrophoretic Mobility Shift Assay; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Liver Cirrhosis, Biliary; NF-kappa B; Promoter Regions, Genetic; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured

2001
The UDCA dosage deficit: a fate shared with CDCA.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:3

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Dose-Response Relationship, Drug; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2002
Primary bile acid kinetics in patients with primary biliary cirrhosis and in normal subjects.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1979, Volume: 2, Issue:1

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged

1979
Phenobarbital effects in cholestatic liver diseases.
    Annals of internal medicine, 1975, Volume: 82, Issue:3

    Topics: Adult; Bile Ducts, Intrahepatic; Bilirubin; Chenodeoxycholic Acid; Child; Child, Preschool; Cholangitis; Cholestasis; Cholic Acids; Feces; Female; Hepatitis; Humans; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Phenobarbital; Pruritus; Rose Bengal; Sulfobromophthalein

1975
Serum bile acids in primary biliary cirrhosis.
    Archives of internal medicine, 1976, Volume: 136, Issue:1

    Topics: Adult; Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Fasting; Female; Humans; Liver; Liver Cirrhosis, Biliary; Male; Middle Aged; Mitochondria

1976
Bile acid therapy in the 1990s.
    Lancet (London, England), 1992, Nov-21, Volume: 340, Issue:8830

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

1992
[Cholestatic liver diseases and modern bile acid therapy (Medica '89)].
    Der Internist, 1990, Volume: 31, Issue:6

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Deoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

1990
Production and properties of antiserum for radioimmunoassay of serum conjugated chenodeoxycholic acid and its preliminary application.
    Acta medica Hungarica, 1985, Volume: 42, Issue:1-2

    Topics: Chenodeoxycholic Acid; Glycochenodeoxycholic Acid; Humans; Immune Sera; Liver Cirrhosis, Biliary; Radioimmunoassay

1985
Spectrofluorimetric determination of individual bile acids in biological fluids: peripheral plasma.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Mar-30, Volume: 44, Issue:3

    Topics: Acetylation; Adolescent; Adult; Aged; Animals; Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Thin Layer; Deoxycholic Acid; Dogs; Female; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Methylation; Middle Aged; Pruritus; Spectrometry, Fluorescence

1973
Excretion of bile acids in extrahepatic biliary atresia and intrahepatic cholestasis of infancy.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:3

    Topics: Autoradiography; Bile Acids and Salts; Bile Ducts; Carbon Isotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Chromatography, Thin Layer; Complement Fixation Tests; Constriction; Creatinine; Diagnosis, Differential; Female; Half-Life; Humans; Infant; Infant, Newborn; Liver Cirrhosis, Biliary; Male; Transaminases; Trypsin Inhibitors

1973