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chenodeoxycholic acid and Acute Liver Injury, Drug-Induced

chenodeoxycholic acid has been researched along with Acute Liver Injury, Drug-Induced in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (52.73)	18.7374
1990's	3 (5.45)	18.2507
2000's	2 (3.64)	29.6817
2010's	18 (32.73)	24.3611
2020's	3 (5.45)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ali, B; Eaton, JE; Kamath, PS; Reddy, R; Sathapathy, S; Vuppalanchi, R	1
Beaudoin, JJ; Bezençon, J; Brouwer, KLR; Fallon, JK; Sjöstedt, N	1
Gao, L; Guo, S; Li, J; Li, Y; Liu, H; Liu, M; Ru, H; Shu, Z; Sun, DD; Tan, Q; Xie, R; Zang, Y; Zhou, Y	1
Cui, Y; Li, R; Ren, Y; Wang, C; Xiong, X; Zhang, Y	1
Aschenbrenner, DS	1
Ashby, K; Borlak, J; Chen, M; Mehta, R; Navarro Almario, EE; Tong, W	1
Rockey, DC	1
Oda, S; Takeuchi, T; Tsuneyama, K; Yang, F; Yokoi, T	1
Afonso, SG; Batlle, A; Buzaleh, AM; Martinez, Mdel C; Meiss, R; Ruspini, SF	1
Bosch, AM; Huidekoper, HH; Vaz, FM; Verrips, A	1
Cai, W; Chen, Y; Gong, Z; Tian, C; Wang, P; Wu, J; Xu, C; Zhao, S; Zhou, J	1
Bridges, AS; Brouwer, KL; Corbett, AH; Kashuba, AD; McRae, M; Rezk, NL; Tien, HC	1
Brouwer, KL; Marion, TL; Perry, CH; St Claire, RL; Yue, W	1
Cipriani, S; D'Amore, C; Distrutti, E; Fiorucci, S; Mencarelli, A; Migliorati, M; Renga, B	1
Chen, J; Chen, M; Lian, F; Liang, L; Wang, Y; Xu, H; Yang, X; Ye, Y; Zhan, Z	1
Alvarez, AR; Amigo, L; Ferrada, C; Galdames, L; Klein, A; Miquel, JF; Morales, MG; Quinones, V; Rigotti, A; Rio, MC; Tichauer, JE; Zanlungo, S	1
Fukunari, A; Imada, T; Ishizaki, K; Iwaki, T; Kinoshita, S; Tanaka, H; Tsurufuji, M	1
Aitio, A; Härkönen, H; Lehtniemi, A	1
Tangedahl, TN	1
Mogadam, M	1
Lachin, JM; Schoenfield, LJ	1
Buffet, C; Chaput, JC; Etienne, JP; Franco, D; Houssin, D; Labayle, D	1
Carey, MC; Palmer, RH	1
Barbara, L; Bazzoli, F; Fromm, H; Roda, A; Roda, E; Sarva, RP	1
Hanson, RF	1
Baker, D; Gochman, N; Javitt, NB; Jones, HM; Miyai, K	1
Forkman, A; Tobiasson, P	1
Fujiwara, K; Matsui, A; Nagoshi, S; Ohta, Y	1
Chen, T; Dyrszka, H; Mosbach, EH; Salen, G; Saltzman, WH	1
Brunner, H; Grabner, G; Horak, W	1
Leuschner, U	1
Bouma, ME; Darnis, F; Infante, R; Lageron, A; Levy, VG	1
Bonorris, GG; Marks, JW; Pearlman, BJ; Schoenfield, LJ	1
Paumgartner, G; Weber, M	1
Ingelfinger, FJ	1
Standaert, LO	1
Allan, RN; Gadacz, TR; Hofmann, AF; Mack, E	1
Glenn, F; May, PS; McSherry, CK; Morrissey, KP; Niemann, WH; Swarm, RL	1
Goldstein, LI; Schoenfield, LJ	1
Deitrick, JE; McSherry, CK; Morrissey, KP; Nieman, WH; Swarm, RL	1
Andersen, RB; Bruusgaard, A	1
Doishita, K; Kitagawa, T; Nonomura, A; Ota, G	1
Berenson, MM; Garcia-Marin, JJ; Welch, V	1
Berenson, MM; Bjorkman, DJ; Gunther, C; Samowitz, WS	1
Alvaro, D; Angelico, M; Attili, AF; Cantafora, A; Capocaccia, L	1
Dowling, RH	1
Cooper, NS; Fischer, CD; Mosbach, EH; Rothschild, MA	1
Lahana, DA; Schoenfield, LJ	1
Schoenfield, LJ	1

Reviews

9 review(s) available for chenodeoxycholic acid and Acute Liver Injury, Drug-Induced

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Review article: therapeutic bile acids and the risks for hepatotoxicity. Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:12 Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Humans; Liver	2018
Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety. Annals of internal medicine, 1981, Volume: 95, Issue:3 Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Diarrhea; Double-Blind Method; Drug Evaluation; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Random Allocation; Sex Factors; Time Factors	1981
Gallstone dissolution--a progress report. Clinics in gastroenterology, 1979, Volume: 8, Issue:1 Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Contraceptives, Oral, Synthetic; Deoxycholic Acid; Diarrhea; Enterohepatic Circulation; Estrogens; Female; Gallstones; Humans; Liver; Male; Phosphatidylcholines; Pregnancy; Recurrence; Risk	1979
[Current status of treatment of gall stones with chenodeoxycholic acid]. Tijdschrift voor gastro-enterologie, 1975, Volume: 18, Issue:1 Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cricetinae; Diarrhea; Digestive System; Dogs; Haplorhini; Humans; Liver; Liver Cirrhosis; Macaca mulatta; Mice; Rabbits; Rats	1975
Gallstones: pathogenesis and medical treatment. Advances in internal medicine, 1975, Volume: 20 Topics: Adult; Animals; Arizona; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Fasting; Female; Guinea Pigs; Humans; Indians, North American; Liver; Male; Middle Aged; Minnesota; Phosphatidylcholines	1975
The goose that laid the golden bile: gallstone dissolution in man with chenodeoxycholic acid. Irish journal of medical science, 1974, Volume: 0, Issue:0 Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholecystectomy; Cholelithiasis; Cholesterol; Cholic Acids; Diarrhea; Dogs; Female; Haplorhini; Humans; Lipid Metabolism; Macaca; Male; Radiography; Rats; Solubility	1974
Progress in medical therapy of gallstones. The Surgical clinics of North America, 1973, Volume: 53, Issue:5 Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Humans	1973
Medical therapy for gallstones. Gastroenterology, 1974, Volume: 67, Issue:4 Topics: Administration, Oral; Bile; Bile Acids and Salts; Bilirubin; Calcium; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Humans; Lithocholic Acid; Liver; Phenobarbital; United States	1974

Trials

3 trial(s) available for chenodeoxycholic acid and Acute Liver Injury, Drug-Induced

Article	Year
Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety. Annals of internal medicine, 1981, Volume: 95, Issue:3 Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Diarrhea; Double-Blind Method; Drug Evaluation; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Random Allocation; Sex Factors; Time Factors	1981
Sounding Board. An optimistic view of the National Cooperative Gallstone Study. The New England journal of medicine, 1982, May-13, Volume: 306, Issue:19 Topics: Bile; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Clinical Trials as Topic; Diarrhea; Humans; Liver; Recurrence; Triglycerides	1982
Hepatic sinusoidal dilatation after chenodeoxycholic-acid therapy. Lancet (London, England), 1978, Jan-28, Volume: 1, Issue:8057 Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Clinical Trials as Topic; Dilatation, Pathologic; Follow-Up Studies; Humans	1978

Other Studies

44 other study(ies) available for chenodeoxycholic acid and Acute Liver Injury, Drug-Induced

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests	2011
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Liver Injury in Patients With Cholestatic Liver Disease Treated With Obeticholic Acid. Hepatology (Baltimore, Md.), 2020, Volume: 71, Issue:4 Topics: Aged; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged	2020
Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions. Toxicological sciences : an official journal of the Society of Toxicology, 2020, 07-01, Volume: 176, Issue:1 Topics: Animals; Bile Acids and Salts; Biological Transport; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Drug Interactions; Hepatocytes; Humans; Ion Transport; Kinetics; Liver; Membrane Transport Proteins; Pharmaceutical Preparations; Proteomics; Taurocholic Acid	2020
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis. Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21 Topics: Animals; Binding Sites; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Drug Design; Drug Evaluation, Preclinical; Half-Life; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship	2020
Obeticholic acid protects mice against lipopolysaccharide-induced liver injury and inflammation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96 Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Hepatocytes; Inflammation; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Protective Agents; Receptors, Cytoplasmic and Nuclear	2017
Excessive Dosing of Obeticholic Acid May Increase Risk of Liver Damage. The American journal of nursing, 2018, Volume: 118, Issue:2 Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholangitis; Dose-Response Relationship, Drug; Gastrointestinal Agents; Humans; United States; United States Food and Drug Administration	2018
Editorial: Advances in Hepatology: 2019. Current opinion in gastroenterology, 2019, Volume: 35, Issue:3 Topics: Antiviral Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; End Stage Liver Disease; Gastroenterology; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Non-alcoholic Fatty Liver Disease; Palliative Care	2019
Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats. Toxicological sciences : an official journal of the Society of Toxicology, 2019, 07-01, Volume: 170, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Disease Models, Animal; Drug Synergism; Female; Ketoconazole; Liver; Liver Function Tests; Rats, Sprague-Dawley	2019
Experimental protoporphyria: effect of bile acids on liver damage induced by griseofulvin. BioMed research international, 2015, Volume: 2015 Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Dehydrocholic Acid; Deoxycholic Acid; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Griseofulvin; Humans; Lipid Peroxidation; Mice; Oxidative Stress; Porphyrins; Protoporphyria, Erythropoietic; Superoxide Dismutase; Ursodeoxycholic Acid	2015
Hepatotoxicity due to chenodeoxycholic acid supplementation in an infant with cerebrotendinous xanthomatosis: implications for treatment. European journal of pediatrics, 2016, Volume: 175, Issue:1 Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Child, Preschool; Encephalitis, Viral; Female; Humans; Infant, Newborn; Neonatal Screening; Parechovirus; Picornaviridae Infections; Xanthomatosis, Cerebrotendinous	2016
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis. Oncotarget, 2016, Dec-20, Volume: 7, Issue:51 Topics: Adenosine Triphosphate; Animals; Bile Ducts; Caspase 3; Caspase Inhibitors; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Inflammasomes; Interleukin-1beta; Kupffer Cells; Ligation; Liver; Liver Cirrhosis; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Reactive Oxygen Species; Receptors, G-Protein-Coupled; RNA Interference; Signal Transduction; Transfection	2016
Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity. Pharmacotherapy, 2010, Volume: 30, Issue:1 Topics: Adult; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Early Diagnosis; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lithocholic Acid; Liver; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Tandem Mass Spectrometry; Taurocholic Acid; Time Factors	2010
Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 120, Issue:2 Topics: Animals; ATP-Binding Cassette Transporters; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Chromans; Chromatography, High Pressure Liquid; Hepatocytes; Male; PPAR gamma; Propionates; Quinolines; Rats; Rats, Wistar; Tandem Mass Spectrometry; Taurocholic Acid; Thiazolidinediones; Troglitazone	2011
SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:6 Topics: Animals; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Gene Expression Regulation; HEK293 Cells; Hepatic Stellate Cells; Humans; Interleukin-1beta; Male; Myofibroblasts; Phenotype; PPAR gamma; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Tumor Necrosis Factor-alpha	2011
Activation of farnesoid X receptor attenuates liver injury in systemic lupus erythematosus. Rheumatology international, 2012, Volume: 32, Issue:6 Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Case-Control Studies; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Concanavalin A; Cytoprotection; Disease Models, Animal; Female; Humans; Inflammation Mediators; Interferon-gamma; Interleukin-6; Liver; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha	2012
Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse. World journal of gastroenterology, 2007, Jun-14, Volume: 13, Issue:22 Topics: Adenoviridae; Alkaline Phosphatase; Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Disease Models, Animal; Gene Expression Regulation; Humans; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Phenotype; Phosphoproteins; Transfection	2007
Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters. World journal of gastroenterology, 2007, Oct-07, Volume: 13, Issue:37 Topics: Alanine Transaminase; Animals; Bile Acids and Salts; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cricetinae; Eating; Liver; Liver Diseases; Mesocricetus; Ursodeoxycholic Acid	2007
Styrene exposure and the liver. Scandinavian journal of work, environment & health, 1984, Volume: 10, Issue:1 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholic Acids; Female; Follow-Up Studies; gamma-Glutamyltransferase; Humans; Liver; Middle Aged; Occupational Diseases; Polystyrenes; Prospective Studies; Styrenes; Time Factors	1984
Management of gallstones. The new option of bile acid therapy. Postgraduate medicine, 1983, Volume: 74, Issue:5 Topics: Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Humans	1983
The GI drug column. The ACG committee on FDA related matters. The American journal of gastroenterology, 1983, Volume: 78, Issue:3 Topics: Alginates; Aluminum Hydroxide; Antacids; Bicarbonates; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cimetidine; Dicyclomine; Drug Combinations; Gastrointestinal Diseases; Humans; Magnesium Hydroxide; Silicic Acid; Simethicone; Sodium Bicarbonate; United States; United States Food and Drug Administration	1983
[Hepatology in 1981]. La Revue du praticien, 1981, Dec-21, Volume: 31, Issue:59 Topics: Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Liver Transplantation; Peliosis Hepatis; Peritoneovenous Shunt; Ursodeoxycholic Acid	1981
Relationship between serum and biliary bile acids as an indicator of chenodeoxycholic and ursodeoxycholic acid-induced hepatotoxicity in the rhesus monkey. Digestive diseases and sciences, 1982, Volume: 27, Issue:5 Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Deoxycholic Acid; Female; Lithocholic Acid; Macaca mulatta; Male; Sulfates; Ursodeoxycholic Acid	1982
Gallstones--the case for medical management. Geriatrics, 1982, Volume: 37, Issue:7 Topics: Aged; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholecystectomy; Cholecystitis; Cholelithiasis; Dietary Fats; Female; Gallstones; Humans; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid	1982
Hepatotoxicity of bile acids in rabbits: ursodeoxycholic acid is less toxic than chenodeoxycholic acid. Laboratory investigation; a journal of technical methods and pathology, 1982, Volume: 46, Issue:4 Topics: Animals; Bile Canaliculi; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cytoskeleton; Deoxycholic Acid; Lithocholic Acid; Liver; Liver Diseases; Prognosis; Rabbits; Ursodeoxycholic Acid	1982
Serum bile acids in acute hepatitis. Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholic Acids; Hepatitis, Viral, Human; Humans; Middle Aged; Radioimmunoassay	1981
Protective action of putrescine against rat liver injury. Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:2 Topics: Administration, Oral; Animals; Carbon Tetrachloride Poisoning; Cell Membrane; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Galactosamine; Lipid Peroxidation; Liver; Liver Diseases; Male; Octoxynol; Peroxides; Putrescine; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide	1994
Letter Prevention of chenodeoxycholic-acid toxicity with lincomycin. Lancet (London, England), 1975, May-10, Volume: 1, Issue:7915 Topics: Animals; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Drug Antagonism; Lincomycin; Liver; Liver Diseases; Macaca mulatta	1975
[Adverse effects of chenodeoxycholic-acid therapy]. Zeitschrift fur Gastroenterologie. Verhandlungsband, 1976, Issue:9 Topics: Animals; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Fatty Liver; Humans	1976
[Liver damage during treatment with cheno-acid: animal experiment results and findings in patients with cheno-acid therapy]. Zeitschrift fur Gastroenterologie. Verhandlungsband, 1976, Issue:9 Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cricetinae; Haplorhini; Humans; Macaca mulatta; Mice; Mitochondria, Liver; Rabbits; Rats	1976
[Surgical, endoscopical and medical treatment of gallstones (author's transl)]. Therapeutische Umschau. Revue therapeutique, 1978, Volume: 35, Issue:9 Topics: Calcium; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholangitis; Cholecystectomy; Cholecystitis; Cholelithiasis; Cholestasis; Cholesterol; Deoxycholic Acid; Humans	1978
Editorial: Testing drugs: men, mice and baboons. The New England journal of medicine, 1975, Sep-04, Volume: 293, Issue:10 Topics: Animals; Blood Coagulation; Blood Platelets; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Drug Evaluation; Haplorhini; Humans; Mice; Papio; Platelet Aggregation; Rabbits; Somatostatin	1975
Impaired lithocholate sulfation in the rhesus monkey: a possible mechanism for chenodeoxycholate toxicity. Gastroenterology, 1976, Volume: 70, Issue:6 Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholic Acids; Female; Haplorhini; Humans; Kinetics; Lithocholic Acid; Macaca mulatta; Species Specificity; Sulfuric Acids	1976
Chenodeoxycholic acid induced liver injury in pregnant and neonatal baboons. Annals of surgery, 1976, Volume: 184, Issue:4 Topics: Animals; Animals, Newborn; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Female; Gallbladder; Haplorhini; Liver; Papio; Pregnancy; Pregnancy Complications	1976
Toxicity of chenodeoxycholic acid in the nonhuman primate. Surgery, 1975, Volume: 77, Issue:6 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Biopsy; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholesterol; Female; Lithocholic Acid; Liver; Papio; Pregnancy	1975
Effect of an intravenously administered bile acid (chenodeoxycholic acid) on rheumatoid arthritis. Scandinavian journal of rheumatology, 1975, Volume: 4, Issue:3 Topics: Adult; Aged; Arthritis, Rheumatoid; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Drug Evaluation; Female; Hematocrit; Humans; Injections, Intravenous; Male; Middle Aged; Time Factors	1975
[An autopsy case of hepatitis probably induced by chenodeoxycholic acid and thiamphenicol author's transl]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1975, Volume: 72, Issue:1 Topics: Anti-Bacterial Agents; Autopsy; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Female; Humans; Liver; Middle Aged; Thiamphenicol	1975
Importance of bile acid structure in amelioration of griseofulvin-induced murine protoporphyric hepatopathy. The Journal of laboratory and clinical medicine, 1991, Volume: 118, Issue:1 Topics: Absorption; Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis, Intrahepatic; Cholic Acid; Cholic Acids; Female; Griseofulvin; Liver; Liver Diseases; Mice; Protoporphyrins; Structure-Activity Relationship; Ursodeoxycholic Acid	1991
Formation of biliary thrombi in protoporphyrin-induced cholestasis in perfused rat liver. Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5 Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Diseases; Microscopy, Electron; Perfusion; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid	1990
Bile acid-induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids. Medical hypotheses, 1986, Volume: 19, Issue:1 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Biotransformation; Cell Membrane; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Detergents; gamma-Glutamyltransferase; Humans; Macaca mulatta; Papio; Rabbits; Taurine	1986
Effect of dietary chenodeoxycholic acid and lithocholic acid in the rabbit. The American journal of digestive diseases, 1974, Volume: 19, Issue:10 Topics: Animals; Appetite; Bile; Bile Acids and Salts; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Deoxycholic Acid; Diet; Lithocholic Acid; Liver; Liver Cirrhosis; Male; Rabbits	1974