chelerythrine has been researched along with Tuberous Sclerosis in 1 studies
chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Medvetz, D | 1 |
| Sun, Y | 1 |
| Li, C | 1 |
| Khabibullin, D | 1 |
| Balan, M | 1 |
| Parkhitko, A | 1 |
| Priolo, C | 1 |
| Asara, JM | 1 |
| Pal, S | 1 |
| Yu, J | 1 |
| Henske, EP | 1 |
1 other study available for chelerythrine and Tuberous Sclerosis
| Article | Year |
|---|---|
High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.
Topics: Benzophenanthridines; Cell Death; Cell Line, Tumor; Drug Screening Assays, Antitumor; Glutathione; H | 2015 |