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chelerythrine and Reperfusion Injury

chelerythrine has been researched along with Reperfusion Injury in 19 studies

chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"Landiolol, a highly cardioselective beta1-blocker, has cardioprotective effects against ischemia-reperfusion injury, although the precise mechanism is still unclear."7.74Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway. ( Hirai, H; Minamiyama, Y; Sakaguchi, M; Sasaki, Y; Shibata, T; Suehiro, S; Takahashi, Y; Takemura, S, 2007)
"Landiolol, a highly cardioselective beta1-blocker, has cardioprotective effects against ischemia-reperfusion injury, although the precise mechanism is still unclear."3.74Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway. ( Hirai, H; Minamiyama, Y; Sakaguchi, M; Sasaki, Y; Shibata, T; Suehiro, S; Takahashi, Y; Takemura, S, 2007)
"Diazoxide is a selective mitochondria ATP-sensitive potassium (K(ATP)) channel opener, which has been reported to preserve the microvascular integrity of ischemia-reperfusion (I/R)-injured tissues."1.33Diazoxide ameliorates microcirculatory disturbances through PKC-dependent pathway in I/R-injured rat cremaster muscles. ( Hung, LM; Wei, FC; Wei, W, 2005)
"This anti-infarction effect of IPC was blocked by Chel (42 +/- 7%) and Poly B (37 +/- 2%) and mimicked by PMA (19 +/- 10%) and OAG (14 +/- 5%) treatments (P < 0."1.31Role and mechanism of PKC in ischemic preconditioning of pig skeletal muscle against infarction. ( Forrest, CR; He, W; Hopper, RA; Neligan, P; Pang, CY; Rutka, J; Xu, H; Zhong, A, 2000)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's10 (52.63)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, B1
Xu, G1
Zheng, Y1
Tong, F1
Qian, P1
Pan, X1
Zhou, X1
Shen, R1
Liu, C1
Liu, Y1
Shen, Z1
Miao, L1
Zhang, K1
Wang, F1
Li, Y2
Eldaif, SM1
Deneve, JA1
Wang, NP1
Jiang, R1
Mosunjac, M1
Mutrie, CJ1
Guyton, RA1
Zhao, ZQ1
Vinten-Johansen, J1
Lu, DQ1
Chen, Y1
Li, T1
Li, BL1
Giaroni, C1
Zanetti, E1
Giuliani, D1
Oldrini, R1
Marchet, S1
Moro, E1
Borroni, P1
Trinchera, M1
Crema, F1
Lecchini, S1
Frigo, G1
Min, TJ1
Kim, JI1
Kim, JH1
Noh, KH1
Kim, TW1
Kim, WY1
Lee, YS1
Park, YC1
Yun, N1
Kim, SH1
Lee, SM1
Ding, HL1
Zhu, HF1
Dong, JW1
Zhu, WZ1
Zhou, ZN1
Schinella, G1
Fantinelli, JC1
Mosca, SM1
Wei, W1
Wei, FC1
Hung, LM1
Bell, RM1
Cave, AC1
Johar, S1
Hearse, DJ1
Shah, AM1
Shattock, MJ1
Sovershaev, MA1
Egorina, EM1
Andreasen, TV1
Jonassen, AK1
Ytrehus, K1
Pan, MX1
Zhang, Y1
Li, AH1
Gao, Y1
Takahashi, Y1
Takemura, S1
Minamiyama, Y1
Shibata, T1
Hirai, H1
Sasaki, Y1
Sakaguchi, M1
Suehiro, S1
Reshef, A1
Sperling, O1
Zoref-Shani, E1
Padua, RR1
Merle, PL1
Doble, BW1
Yu, CH1
Zahradka, P1
Pierce, GN1
Panagia, V1
Kardami, E1
Hopper, RA1
Forrest, CR1
Xu, H1
Zhong, A1
He, W1
Rutka, J1
Neligan, P1
Pang, CY1
Sato, T1
Zhou, HZ1
Karliner, JS1
Gray, MO1

Other Studies

19 other studies available for chelerythrine and Reperfusion Injury

ArticleYear
Chelerythrine Attenuates Renal Ischemia/Reperfusion-induced Myocardial Injury by Activating CSE/H2S via PKC/NF-κB Pathway in Diabetic Rats.
    Kidney & blood pressure research, 2017, Volume: 42, Issue:2

    Topics: Animals; Benzophenanthridines; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Ischemic

2017
Sevoflurane Preconditioning Reduces Intestinal Ischemia-Reperfusion Injury: Role of Protein Kinase C and Mitochondrial ATP-Sensitive Potassium Channel.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Animals; Benzophenanthridines; Intestinal Mucosa; Intestines; Ischemic Preconditioning; KATP Channel

2015
Attenuation of renal ischemia-reperfusion injury by postconditioning involves adenosine receptor and protein kinase C activation.
    Transplant international : official journal of the European Society for Organ Transplantation, 2010, Volume: 23, Issue:2

    Topics: Animals; Apoptosis; Benzophenanthridines; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; E

2010
[Role of protein kinase C in protecting rats against pulmonary ischemia reperfusion injury through opening of mitochondrial ATP sensitive potassium channel].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:3

    Topics: Animals; Benzophenanthridines; Female; KATP Channels; Lung; Male; Mitochondria; Protein Kinase C; Ra

2010
Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Benzophenanthridines; Guinea Pigs; Ileum; In Vitro Techniques;

2011
Morphine postconditioning attenuates ICAM-1 expression on endothelial cells.
    Journal of Korean medical science, 2011, Volume: 26, Issue:2

    Topics: Animals; Benzophenanthridines; Endothelial Cells; Endothelium, Vascular; Humans; Intercellular Adhes

2011
Differential consequences of protein kinase C activation during early and late hepatic ischemic preconditioning.
    The journal of physiological sciences : JPS, 2012, Volume: 62, Issue:3

    Topics: Acetophenones; Animals; Apoptosis; Benzophenanthridines; Benzopyrans; Cytochromes c; Heme Oxygenase-

2012
Intermittent hypoxia protects the rat heart against ischemia/reperfusion injury by activating protein kinase C.
    Life sciences, 2004, Oct-08, Volume: 75, Issue:21

    Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Cells, Cultured; Coronary Circulation; Heart Vent

2004
Cardioprotective effects of Ilex paraguariensis extract: evidence for a nitric oxide-dependent mechanism.
    Clinical nutrition (Edinburgh, Scotland), 2005, Volume: 24, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; Cardiotonic Agents; Ilex paraguariensis; In Vitro Techniqu

2005
Diazoxide ameliorates microcirculatory disturbances through PKC-dependent pathway in I/R-injured rat cremaster muscles.
    Journal of biomedical science, 2005, Volume: 12, Issue:3

    Topics: Abdominal Muscles; Alkaloids; Animals; Benzophenanthridines; Cell Adhesion Molecules; Cell Movement;

2005
Pivotal role of NOX-2-containing NADPH oxidase in early ischemic preconditioning.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:14

    Topics: Acridines; Alkaloids; Animals; Benzophenanthridines; Coloring Agents; Heart; Ischemia; Ischemic Prec

2005
Preconditioning by 17beta-estradiol in isolated rat heart depends on PI3-K/PKB pathway, PKC, and ROS.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:4

    Topics: Alkaloids; Androstadienes; Animals; Benzophenanthridines; Dose-Response Relationship, Drug; Enzyme I

2006
[Protective effect of protein kinase C and mitogen-activated protein kinases and its mechanism in liver ischemic preconditioning].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:8

    Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Benzophenanthridines; Enzyme

2006
Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway.
    Free radical research, 2007, Volume: 41, Issue:7

    Topics: Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Cardiotonic Agents; Glyburide

2007
Activation and inhibition of protein kinase C protect rat neuronal cultures against ischemia-reperfusion insult.
    Neuroscience letters, 1997, Nov-28, Volume: 238, Issue:1-2

    Topics: Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Diglycerides; Enzyme Activation; Enzyme I

1997
FGF-2-induced negative inotropism and cardioprotection are inhibited by chelerythrine: involvement of sarcolemmal calcium-independent protein kinase C.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:12

    Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent P

1998
Role and mechanism of PKC in ischemic preconditioning of pig skeletal muscle against infarction.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:2

    Topics: Adenosine; Alkaloids; Animals; Benzophenanthridines; Biological Transport; Decanoic Acids; Diglyceri

2000
Dual signaling via protein kinase C and phosphatidylinositol 3'-kinase/Akt contributes to bradykinin B2 receptor-induced cardioprotection in guinea pig hearts.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:11

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Benzophenanthridines; Blotting, Western; Bradykinin; Dec

2001
Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Body Weight; Creatine Kinase; Enzyme Activation; Enzyme In

2002