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chelerythrine and Necrosis

chelerythrine has been researched along with Necrosis in 12 studies

chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" Preconditioning with 10 microM adenosine limited necrosis (10."3.72Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects. ( Headrick, JP; Peart, J, 2003)
"Chelerythrine was selected for further studies based on its cytotoxicity and the lack of apoptotic nuclear alterations."1.42An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death. ( Casanelles, E; Garcia-Belinchón, M; Granados-Colomina, C; Iglesias-Guimarais, V; Martínez-Escardó, L; Pascual-Guiral, S; Ribas, J; Sánchez-Osuna, M; Yuste, VJ, 2015)
"Treatment with chelerythrine alone or the PKCepsilon antagonist KIE1-1 alone at reperfusion had no effect on infarct size compared to control."1.33Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling. ( Guyton, RA; Jiang, R; Kin, H; Lee, G; Lust, R; Mykytenko, J; Reeves, JG; Vinten-Johansen, J; Wang, N; Zatta, AJ; Zhao, ZQ, 2006)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's8 (66.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, WX1
Li, T1
Tang, ZH1
Zhang, LL1
Wang, ZY1
Guo, X1
Su, MX1
Chen, X1
Lu, JJ1
Garcia-Belinchón, M1
Sánchez-Osuna, M1
Martínez-Escardó, L1
Granados-Colomina, C1
Pascual-Guiral, S1
Iglesias-Guimarais, V1
Casanelles, E1
Ribas, J1
Yuste, VJ1
Mioulane, M1
Foldes, G1
Ali, NN1
Schneider, MD1
Harding, SE1
Peart, J1
Headrick, JP1
Penna, C1
Alloatti, G1
Cappello, S1
Gattullo, D1
Berta, G1
Mognetti, B1
Losano, G1
Pagliaro, P1
Kemény-Beke, A1
Aradi, J1
Damjanovich, J1
Beck, Z1
Facskó, A1
Berta, A1
Bodnár, A1
Zatta, AJ1
Kin, H1
Lee, G1
Wang, N1
Jiang, R1
Lust, R1
Reeves, JG1
Mykytenko, J1
Guyton, RA1
Zhao, ZQ1
Vinten-Johansen, J1
Kubal, C1
Sheth, K1
Nadal-Ginard, B1
Galiñanes, M1
Townsend, PA1
Davidson, SM1
Clarke, SJ1
Khaliulin, I1
Carroll, CJ1
Scarabelli, TM1
Knight, RA1
Stephanou, A1
Latchman, DS1
Halestrap, AP1
Diaz, RJ1
Losito, VA1
Mao, GD1
Ford, MK1
Backx, PH1
Wilson, GJ1
Yamamoto, S1
Seta, K1
Morisco, C1
Vatner, SF1
Sadoshima, J1
Gunasekar, P1
Li, L1
Prabhakaran, K1
Eybl, V1
Borowitz, JL1
Isom, GE1

Other Studies

12 other studies available for chelerythrine and Necrosis

ArticleYear
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation.
    Apoptosis : an international journal on programmed cell death, 2018, Volume: 23, Issue:9-10

    Topics: Apoptosis; Benzophenanthridines; Cell Nucleus; eIF-2 Kinase; Endoplasmic Reticulum; Eukaryotic Initi

2018
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
    The Journal of biological chemistry, 2015, Aug-21, Volume: 290, Issue:34

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzophen

2015
Development of high content imaging methods for cell death detection in human pluripotent stem cell-derived cardiomyocytes.
    Journal of cardiovascular translational research, 2012, Volume: 5, Issue:5

    Topics: Animals; Animals, Newborn; Apoptosis; Automation, Laboratory; Benzophenanthridines; Caspases, Effect

2012
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.
    Cardiovascular research, 2003, Jun-01, Volume: 58, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers

2003
Platelet-activating factor induces cardioprotection in isolated rat heart akin to ischemic preconditioning: role of phosphoinositide 3-kinase and protein kinase C activation.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Alkaloids; Animals; Azepines; Benzophenanthridines; Cardiotonic Agents; Chromones; Coronary Circulat

2005
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine.
    Cancer letters, 2006, Jun-08, Volume: 237, Issue:1

    Topics: Alkaloids; Annexin A5; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Berberine Alkaloids;

2006
Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling.
    Cardiovascular research, 2006, May-01, Volume: 70, Issue:2

    Topics: Acetophenones; Alkaloids; Animals; Benzophenanthridines; Benzopyrans; Blotting, Western; Cytosol; Ma

2006
Bone marrow cells have a potent anti-ischemic effect against myocardial cell death in humans.
    The Journal of thoracic and cardiovascular surgery, 2006, Volume: 132, Issue:5

    Topics: Alkaloids; Apoptosis; Benzophenanthridines; Bone Marrow Cells; Cell Death; Heart; Heart Atria; Human

2006
Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2

    Topics: Alkaloids; Animals; Animals, Newborn; Antioxidants; Benzophenanthridines; Calcium; Cardiotonic Agent

2007
Chloride channel inhibition blocks the protection of ischemic preconditioning and hypo-osmotic stress in rabbit ventricular myocardium.
    Circulation research, 1999, Apr-16, Volume: 84, Issue:7

    Topics: Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Chloride Channels; Electrophysiology; Enz

1999
Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:10

    Topics: Acetylcysteine; Adenoviridae; Alkaloids; Animals; Animals, Newborn; Annexin A5; Antioxidants; Apopto

2001
Mechanisms of the apoptotic and necrotic actions of trimethyltin in cerebellar granule cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 64, Issue:1

    Topics: Alkaloids; Animals; Apoptosis; Benzophenanthridines; Catalase; Cells, Cultured; Cerebellum; Dizocilp

2001