Page last updated: 2024-10-24

chelerythrine and Myocardial Ischemia

chelerythrine has been researched along with Myocardial Ischemia in 51 studies

chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Landiolol, a highly cardioselective beta1-blocker, has cardioprotective effects against ischemia-reperfusion injury, although the precise mechanism is still unclear."7.74Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway. ( Hirai, H; Minamiyama, Y; Sakaguchi, M; Sasaki, Y; Shibata, T; Suehiro, S; Takahashi, Y; Takemura, S, 2007)
"Landiolol, a highly cardioselective beta1-blocker, has cardioprotective effects against ischemia-reperfusion injury, although the precise mechanism is still unclear."3.74Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway. ( Hirai, H; Minamiyama, Y; Sakaguchi, M; Sasaki, Y; Shibata, T; Suehiro, S; Takahashi, Y; Takemura, S, 2007)
" Intravenous injection of protein kinase C inhibitors chelerythrine (5 mg/kg) and staurosporine (50 microg/kg) or a specific mitochondrial K(ATP) channel inhibitor 5-hydroxydecanoate (5 mg/kg) 5 min before sustained myocardial ischemia abolished the preconditioning afforded by intestinal ischemia."3.71Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel. ( Maeta, H; Mizoguchi, K; Oe, M; Suzuki, T; Wang, YP; Yamashita, Y, 2002)
"Chelerythrine (5 mg/kg) was injected before EP to investigate the role of PKC in EP."1.40Exercise preconditioning-induced early and late phase of cardioprotection is associated with protein kinase C epsilon translocation. ( Ge, J; Hao, Z; Pan, SS; Shen, YJ, 2014)
"Pretreatment with Zaprinast neither induced HSP72 expression nor reduced infarct size ((55."1.35Nitric oxide induces heat shock protein 72 production and delayed protection against myocardial ischemia in rabbits via activating protein kinase C. ( Guo, WY; Hori, M; Jia, GL; Kitakaze, M; Li, F; Li, WJ; Liu, B; Wang, HC; Zhang, DX; Zhao, ZJ, 2008)
"Treatment with adenosine only at the onset of prolonged ischemia afforded a dose-dependent protection."1.30Preconditioning of isolated rabbit cardiomyocytes: no evident separation of induction, memory and protection. ( Armstrong, SC; Ganote, CE; Hoover, DB; Shivell, LC, 1997)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's21 (41.18)18.2507
2000's25 (49.02)29.6817
2010's5 (9.80)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hao, Z3
Pan, SS4
Shen, YJ4
Ge, J3
Zhong, B1
Wang, DH1
Baharvand, B1
Dehaj, ME1
Rasoulian, B1
Namdari, M1
Shikhani, Y1
Kiani, AA1
Li, WJ1
Zhao, ZJ1
Liu, B1
Zhang, DX1
Li, F1
Wang, HC1
Guo, WY1
Jia, GL1
Kitakaze, M1
Hori, M1
Edwards, AG1
Rees, ML1
Gioscia, RA1
Zachman, DK1
Lynch, JM1
Browder, JC1
Chicco, AJ1
Moore, RL1
Zhuang, T1
Wang, FJ1
Mao, HJ1
Chen, BP1
Wang, HP1
Gao, YF1
Xia, Q1
Wang, YP1
Maeta, H1
Mizoguchi, K1
Suzuki, T1
Yamashita, Y1
Oe, M1
Yamamoto, S1
Yang, G1
Zablocki, D1
Liu, J1
Hong, C1
Kim, SJ1
Soler, S1
Odashima, M1
Thaisz, J1
Yehia, G1
Molina, CA1
Yatani, A1
Vatner, DE1
Vatner, SF1
Sadoshima, J1
Wang, QD1
Nygren, E1
Okawa, H1
Horimoto, H1
Mieno, S1
Nomura, Y1
Yoshida, M1
Shinjiro, S1
Loubani, M1
Hassouna, A1
Galiñanes, M2
Hilfiker-Kleiner, D1
Kaminski, K1
Kaminska, A1
Fuchs, M1
Klein, G1
Podewski, E1
Grote, K1
Kiian, I1
Wollert, KC1
Hilfiker, A1
Drexler, H1
Ding, HL1
Zhu, HF1
Dong, JW1
Zhu, WZ1
Zhou, ZN1
Xu, P1
Wang, J1
Kodavatiganti, R1
Zeng, Y1
Kass, IS1
Rorabaugh, BR1
Ross, SA1
Gaivin, RJ1
Papay, RS1
McCune, DF1
Simpson, PC1
Perez, DM1
Hatanaka, K1
Kawata, H1
Toyofuku, T1
Yoshida, K1
Ritchie, RH1
Gordon, JM1
Woodman, OL1
Cao, AH1
Dusting, GJ1
Bae, S1
Zhang, L1
Kubal, C1
Sheth, K1
Nadal-Ginard, B1
Takahashi, Y1
Takemura, S1
Minamiyama, Y1
Shibata, T1
Hirai, H1
Sasaki, Y1
Sakaguchi, M1
Suehiro, S1
Baxter, GF1
Goma, FM1
Yellon, DM3
Speechly-Dick, ME2
Grover, GJ1
Liu, Y1
Cohen, MV3
Downey, JM3
Bugge, E1
Ytrehus, K1
Mocanu, MM1
Rehring, TF1
Friese, RS1
Cleveland, JC2
Meng, X1
Robertson, FG1
Harken, AH2
Bannerjee, A1
Moolman, JA1
Genade, S1
Tromp, E1
Lochner, A1
Meldrum, DR1
Mitchell, MB1
Sheridan, BC1
Gamboni-Robertson, F1
Banerjee, A1
Cope, DK1
Impastato, WK1
Armstrong, SC1
Hoover, DB1
Shivell, LC1
Ganote, CE1
Kremastinos, DT1
Rohs, TJ1
Kilgore, KS1
Georges, AJ1
Bolling, SF1
Miyawaki, H1
Wang, Y3
Ashraf, M2
Miki, T1
Diaz, RJ1
Losito, VA1
Mao, GD1
Ford, MK1
Backx, PH1
Wilson, GJ1
Ping, P2
Zhang, J2
Cao, X2
Li, RC2
Kong, D1
Tang, XL2
Qiu, Y2
Manchikalapudi, S1
Auchampach, JA1
Black, RG1
Bolli, R2
Lundmark, JL1
Ramasamy, R1
Vulliet, PR1
Schaefer, S1
Vinokurov, AA1
Boldyrev, AA1
Chesnokov, DN1
Dmitrashchuk, AI1
Alabovskiĭ, VV1
Huang, S1
Zheng, YT1
Clerk, A1
Sugden, P1
Han, J1
Falck, G1
Schjott, J1
Jynge, P1
Maczewski, M1
Beresewicz, A1
Rakhit, RD1
Edwards, RJ1
Mockridge, JW1
Baydoun, AR1
Wyatt, AW1
Mann, GE1
Marber, MS1
Ito, K1
Shigematsu, S1
Sato, T1
Abe, T1
Li, Y1
Arita, M1
Fryer, RM1
Hsu, AK1
Gross, GJ1
Munakata, M1
Stamm, C1
Friehs, I1
Zurakowski, D1
Cowan, DB1
Cao-Danh, H1
McGowan, FX1
del Nido, PJ1
Jin, ZQ1
Zhou, HZ2
Zhu, P1
Honbo, N1
Mochly-Rosen, D1
Messing, RO1
Goetzl, EJ1
Karliner, JS2
Gray, MO2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Eplerenone on Ischemia Reperfusion Injury in Human Myocardium (EPLICARD Study)[NCT02118753]24 participants (Actual)Interventional2014-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for chelerythrine and Myocardial Ischemia

ArticleYear
Ischemic preconditioning of the heart.
    Basic research in cardiology, 1997, Volume: 92 Suppl 2

    Topics: Adenosine; Alkaloids; Animals; Benzophenanthridines; Cardiovascular Agents; Drug Therapy, Combinatio

1997

Other Studies

50 other studies available for chelerythrine and Myocardial Ischemia

ArticleYear
Exercise preconditioning-induced early and late phase of cardioprotection is associated with protein kinase C epsilon translocation.
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:7

    Topics: Animals; Antineoplastic Agents; Benzophenanthridines; Cytoplasm; Enzyme Activation; Male; Myocardial

2014
Exercise preconditioning-induced late phase of cardioprotection against exhaustive exercise: possible role of protein kinase C delta.
    The journal of physiological sciences : JPS, 2014, Volume: 64, Issue:5

    Topics: Animals; Benzophenanthridines; Cardiotonic Agents; Heart Ventricles; Male; Myocardial Ischemia; Myoc

2014
N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2

    Topics: Animals; Benzophenanthridines; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Rece

2008
Delayed anti-arrhythmic effect of nitroglycerin in anesthetized rats: involvement of CGRP, PKC and mK ATP channels.
    International journal of cardiology, 2009, Jun-26, Volume: 135, Issue:2

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzophenanthridines; Calcitonin

2009
Nitric oxide induces heat shock protein 72 production and delayed protection against myocardial ischemia in rabbits via activating protein kinase C.
    Chinese medical journal, 2008, Jun-20, Volume: 121, Issue:12

    Topics: Animals; Benzophenanthridines; Cyclic GMP; Hemodynamics; HSP72 Heat-Shock Proteins; Male; Myocardial

2008
PKC-permitted elevation of sarcolemmal KATP concentration may explain female-specific resistance to myocardial infarction.
    The Journal of physiology, 2009, Dec-01, Volume: 587, Issue:Pt 23

    Topics: Animals; ATP-Binding Cassette Transporters; Benzophenanthridines; Blotting, Western; Coronary Circul

2009
Exercise preconditioning initiates late cardioprotection against isoproterenol-induced myocardial injury in rats independent of protein kinase C.
    The journal of physiological sciences : JPS, 2011, Volume: 61, Issue:1

    Topics: Animals; Benzophenanthridines; Isoproterenol; Male; Microscopy, Electron, Transmission; Myocardial I

2011
[The study of effects and mechanism of U50, 488H on electrical coupling during ischemia in the perfused isolated rat heart].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2010, Volume: 26, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; B

2010
Exercise preconditioning provides early cardioprotection against exhaustive exercise in rats: potential involvement of protein kinase C delta translocation.
    Molecular and cellular biochemistry, 2012, Volume: 368, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Benzophenanthridines; Enzyme Activation; Male; Muscle Proteins; Myoc

2012
Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel.
    Cardiovascular research, 2002, Aug-15, Volume: 55, Issue:3

    Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Blood Pressure; Decanoic Acids; Enzy

2002
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:10

    Topics: Alkaloids; Animals; Apoptosis; Benzophenanthridines; Cardiomegaly; Cardiomyopathy, Dilated; Caspase

2003
Various inotropic effects of angiotensin II in post-ischaemic rat hearts depending on ischaemic time with possible involvement of protein kinase C.
    Acta physiologica Scandinavica, 2003, Volume: 178, Issue:3

    Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Blood Pressure; Cardiotonic Agents; Heart;

2003
Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotective effects against ischemia reperfusion in isolated rat hearts.
    Molecular and cellular biochemistry, 2003, Volume: 248, Issue:1-2

    Topics: Adenosine Triphosphate; Alkaloids; Animals; Atrial Natriuretic Factor; Benzophenanthridines; Cyclic

2003
Delayed preconditioning of the human myocardium: signal transduction and clinical implications.
    Cardiovascular research, 2004, Feb-15, Volume: 61, Issue:3

    Topics: Acetylcholine; Aged; Alkaloids; Anisomycin; Antihypertensive Agents; Benzophenanthridines; Culture T

2004
Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation.
    Circulation, 2004, May-11, Volume: 109, Issue:18

    Topics: Alkaloids; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoat

2004
Intermittent hypoxia protects the rat heart against ischemia/reperfusion injury by activating protein kinase C.
    Life sciences, 2004, Oct-08, Volume: 75, Issue:21

    Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Cells, Cultured; Coronary Circulation; Heart Vent

2004
Activation of protein kinase C contributes to the isoflurane-induced improvement of functional and metabolic recovery in isolated ischemic rat hearts.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:4

    Topics: Adenosine Triphosphate; Alkaloids; Anesthetics, Inhalation; Animals; Benzophenanthridines; Energy Me

2004
alpha1A- but not alpha1B-adrenergic receptors precondition the ischemic heart by a staurosporine-sensitive, chelerythrine-insensitive mechanism.
    Cardiovascular research, 2005, Feb-01, Volume: 65, Issue:2

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Inhibitors; Female; Ischemic Preconditioning, Myoca

2005
Down-regulation of connexin43 in early myocardial ischemia and protective effect by ischemic preconditioning in rat hearts in vivo.
    Japanese heart journal, 2004, Volume: 45, Issue:6

    Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Northern; Connexin 43; Down-Regulation; Immunohi

2004
Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia.
    British journal of pharmacology, 2005, Volume: 145, Issue:4

    Topics: Alkaloids; Analysis of Variance; Animals; Annexin A1; Benzophenanthridines; Cells, Cultured; Creatin

2005
Gender differences in cardioprotection against ischemia/reperfusion injury in adult rat hearts: focus on Akt and protein kinase C signaling.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Alkaloids; Androstadienes; Animals; Benzophenanthridines; Blotting, Western; Enzyme Activation; Fema

2005
Bone marrow cells have a potent anti-ischemic effect against myocardial cell death in humans.
    The Journal of thoracic and cardiovascular surgery, 2006, Volume: 132, Issue:5

    Topics: Alkaloids; Apoptosis; Benzophenanthridines; Bone Marrow Cells; Cell Death; Heart; Heart Atria; Human

2006
Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway.
    Free radical research, 2007, Volume: 41, Issue:7

    Topics: Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Cardiotonic Agents; Glyburide

2007
Involvement of protein kinase C in the delayed cytoprotection following sublethal ischaemia in rabbit myocardium.
    British journal of pharmacology, 1995, Volume: 115, Issue:2

    Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Blood Pressure; Cadmium; Cadmium Com

1995
Does ischemic preconditioning in the human involve protein kinase C and the ATP-dependent K+ channel? Studies of contractile function after simulated ischemia in an atrial in vitro model.
    Circulation research, 1995, Volume: 77, Issue:5

    Topics: Adenosine Triphosphate; Adult; Aged; Alkaloids; Benzophenanthridines; Benzopyrans; Cromakalim; Digly

1995
Chelerythrine, a highly selective protein kinase C inhibitor, blocks the anti-infarct effect of ischemic preconditioning in rabbit hearts.
    Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:6

    Topics: Alkaloids; Animals; Benzophenanthridines; Female; Male; Myocardial Infarction; Myocardial Ischemia;

1994
Ischaemic preconditioning is protein kinase C dependent but not through stimulation of alpha adrenergic or adenosine receptors in the isolated rat heart.
    Cardiovascular research, 1995, Volume: 29, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; In Vitro Techniques; Male; Myocardial Infarction; Myocardi

1995
Protein kinase C. Its role in ischemic preconditioning in the rat.
    Circulation research, 1994, Volume: 75, Issue:3

    Topics: Alkaloids; Analysis of Variance; Animals; Arrhythmias, Cardiac; Benzophenanthridines; Blood Pressure

1994
Alpha-adrenergic preservation of myocardial pH during ischemia is PKC isoform dependent.
    The Journal of surgical research, 1996, Volume: 63, Issue:1

    Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Calcium; Diglycerides; Enzyme Inhibi

1996
No evidence for mediation of ischemic preconditioning by alpha 1-adrenergic signal transduction pathway or protein kinase C in the isolated rat heart.
    Cardiovascular drugs and therapy, 1996, Volume: 10, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; Card

1996
Protein kinase C mediates Ca2(+)-induced cardioadaptation to ischemia-reperfusion injury.
    The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 2

    Topics: Adaptation, Physiological; Alkaloids; Animals; Benzophenanthridines; Biological Transport; Calcium;

1996
Volatile anesthetics protect the ischemic rabbit myocardium from infarction.
    Anesthesiology, 1997, Volume: 86, Issue:3

    Topics: Adenosine; Alkaloids; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Benzophenanthridin

1997
Preconditioning of isolated rabbit cardiomyocytes: no evident separation of induction, memory and protection.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8

    Topics: Adenosine; Alkaloids; Animals; Benzophenanthridines; Cardiovascular Agents; Cells, Cultured; Enzyme

1997
Postischemic function and protein kinase C signal transduction.
    The Annals of thoracic surgery, 1998, Volume: 65, Issue:6

    Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Bicarbonates; Calcium Chloride; Cardioplegi

1998
Oxidant stress with hydrogen peroxide attenuates calcium paradox injury: role of protein kinase C and ATP-sensitive potassium channel.
    Cardiovascular research, 1998, Volume: 37, Issue:3

    Topics: Adenosine Triphosphate; Alkaloids; Animals; Anti-Arrhythmia Agents; Benzophenanthridines; Calcium; C

1998
Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits.
    Molecular and cellular biochemistry, 1998, Volume: 186, Issue:1-2

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Tec

1998
Chloride channel inhibition blocks the protection of ischemic preconditioning and hypo-osmotic stress in rabbit ventricular myocardium.
    Circulation research, 1999, Apr-16, Volume: 84, Issue:7

    Topics: Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Chloride Channels; Electrophysiology; Enz

1999
PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Alkaloids; Amino Acid Sequence; Animals; Benzophenanthridines; Calcium-Calmodulin-Dependent Protein

1999
Role of protein kinase C in mitochondrial KATP channel-mediated protection against Ca2+ overload injury in rat myocardium.
    Circulation research, 1999, May-28, Volume: 84, Issue:10

    Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channel Blockers;

1999
Chelerythrine increases Na-K-ATPase activity and limits ischemic injury in isolated rat hearts.
    The American journal of physiology, 1999, Volume: 277, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Activation; Enzyme Inhibitors; Male; Myocardial Isc

1999
[Protein kinase C inhibitors block contractions of the ischemic myocardium caused by acetylcarnosine].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 128, Issue:9

    Topics: Adenine Nucleotides; Alkaloids; Animals; Benzophenanthridines; Carnosine; Enzyme Inhibitors; Indoles

1999
PKC-dependent activation of p46/p54 JNKs during ischemic preconditioning in conscious rabbits.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Activation; Enzyme Inhibitors; Ischemic Preconditio

1999
Hyperosmotic pretreatment reduces infarct size in the rat heart.
    Physiological research, 1999, Volume: 48, Issue:5

    Topics: Alkaloids; Animals; Benzophenanthridines; Fluorescent Dyes; Gadolinium; Guanidines; In Vitro Techniq

1999
The role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:2

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Alkaloids; Angiotensin-Converting Enzyme Inhibitors; An

2000
Nitric oxide-induced cardioprotection in cultured rat ventricular myocytes.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:4

    Topics: Alkaloids; Animals; Animals, Newborn; Anti-Infective Agents; Benzophenanthridines; Cells, Cultured;

2000
JTV-519, a novel cardioprotective agent, improves the contractile recovery after ischaemia-reperfusion in coronary perfused guinea-pig ventricular muscles.
    British journal of pharmacology, 2000, Volume: 130, Issue:4

    Topics: Action Potentials; Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel

2000
Essential activation of PKC-delta in opioid-initiated cardioprotection.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3

    Topics: Acetophenones; Alkaloids; Analgesics; Animals; Benzophenanthridines; Benzopyrans; Benzylidene Compou

2001
Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C.
    The Annals of thoracic surgery, 2002, Volume: 73, Issue:4

    Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Calcium; Corona

2002
Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6

    Topics: Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Blotting, Western; Cells, Cultured; Crea

2002
Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Body Weight; Creatine Kinase; Enzyme Activation; Enzyme In

2002