chelerythrine has been researched along with Muscle Contraction in 36 studies
chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pre-treatment with chelerythrine (1 µM) blocked the actions of DCA on the I(Ca-L)." | 5.38 | Deoxycholic acid inhibits smooth muscle contraction via protein kinase C-dependent modulation of L-type Ca2+ channels in rat proximal colon. ( Hu, LD; Yang, B; Yu, BP, 2012) |
| " ATP significantly increased the strength of muscle contraction induced by carbachol." | 3.73 | Role of protein kinase C in the effect of ATP on contractile function of the isolated strip from mouse diaphragm. ( Grishin, SN; Teplov, AY; Zefirov, AL; Ziganshin, AU, 2006) |
| " Studies were designed to identify PKC isoforms present and to investigate their roles in phenylephrine-induced muscle contraction in the isolated rat corpora cavernosa." | 3.72 | Role of PKCalpha and PKCiota in phenylephrine-induced contraction of rat corpora cavernosa. ( Husain, S; Wingard, CJ; Young, D, 2004) |
| " In order to further elucidate differences in the cellular signalling pathways through which ACh and AF3 elicit muscle contraction, we investigated the actions of protein kinase C inhibitors, tamoxifen and chelerythrine, on the dorsal somatic muscle strip of A." | 3.70 | The inhibitory action of tamoxifen on the contraction of Ascaris suum somatic muscle in response to acetylcholine. ( Holden-Dye, L; Trim, N; Walker, RJ, 1999) |
| " Dexmedetomidine dose-response curves were generated in the presence or absence of the following inhibitors: the pan-PKC inhibitor, chelerythrine; the PKC-α and -β inhibitor, Go6976; the PKC-α inhibitor, safingol; the PKC-β inhibitor, ruboxistaurin; the PKC-δ inhibitor, rottlerin; the c-Jun NH2-terminal kinase (JNK) inhibitor, SP600125; and the myosin light chain kinase inhibitor, ML-7 hydrochloride." | 1.42 | Dexmedetomidine-Induced Contraction in the Isolated Endothelium-Denuded Rat Aorta Involves PKC-δ-mediated JNK Phosphorylation. ( Cho, H; Choi, MJ; Chung, YK; Kim, WH; Kwon, SC; Lee, HK; Ok, SH; Park, J; Shin, IW; Sohn, JT; Yu, J, 2015) |
| " SP600125 (a c-Jun NH2-terminal kinase [JNK] inhibitor) dose-response curves were generated in aortas that were pre-contracted with DMT or phorbol 12,13-dibutyrate (PDBu), a protein kinase C (PKC) activator." | 1.40 | Dexmedetomidine-induced contraction involves phosphorylation of caldesmon by JNK in endothelium-denuded rat aortas. ( Baik, J; Cho, H; Choi, MJ; Kim, W; Lee, HK; Nam, IK; Ok, SH; Sohn, JT; Yu, J, 2014) |
| "Pre-treatment with chelerythrine (1 µM) blocked the actions of DCA on the I(Ca-L)." | 1.38 | Deoxycholic acid inhibits smooth muscle contraction via protein kinase C-dependent modulation of L-type Ca2+ channels in rat proximal colon. ( Hu, LD; Yang, B; Yu, BP, 2012) |
| "Curcumin is an active principle contained in rhizome of Curcuma longa, and it has been recently mentioned to show affinity to muscarinic M-1 cholinoceptors (M(1)-mAChR)." | 1.36 | Activation of muscarinic M-1 cholinoceptors by curcumin to increase contractility in urinary bladder isolated from Wistar rats. ( Cheng, JT; Cheng, TC; Chung, HH; Hsu, CC; Kakizawa, N; Lu, CC; Yamada, S, 2010) |
| "Adenosine (10 microM) was used as other contractile agent for comparison." | 1.35 | Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis. ( Gok, S; Izanli-Paksoy, A; Vural, K, 2009) |
| "Chelerythrine (12 micro M) was shown to restore ECC in these fibres." | 1.32 | The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat. ( Bakker, AJ; Han, R, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (16.67) | 18.2507 |
| 2000's | 20 (55.56) | 29.6817 |
| 2010's | 10 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kline, LW | 2 |
| Karpinski, E | 2 |
| Baik, J | 2 |
| Ok, SH | 3 |
| Cho, H | 2 |
| Yu, J | 2 |
| Kim, W | 1 |
| Nam, IK | 1 |
| Choi, MJ | 2 |
| Lee, HK | 2 |
| Sohn, JT | 3 |
| Kim, WH | 1 |
| Park, J | 1 |
| Shin, IW | 1 |
| Chung, YK | 1 |
| Kwon, SC | 2 |
| Hong, JM | 1 |
| Oh, J | 1 |
| Han, JY | 1 |
| Khin, PP | 1 |
| Zaw, TS | 1 |
| Sohn, UD | 3 |
| Jin, L | 1 |
| Teixeira, CE | 1 |
| Webb, RC | 1 |
| Leite, R | 1 |
| Sims, SM | 1 |
| Chrones, T | 1 |
| Preiksaitis, HG | 1 |
| Gok, S | 1 |
| Izanli-Paksoy, A | 1 |
| Vural, K | 1 |
| Cheng, TC | 1 |
| Lu, CC | 1 |
| Chung, HH | 1 |
| Hsu, CC | 1 |
| Kakizawa, N | 1 |
| Yamada, S | 1 |
| Cheng, JT | 1 |
| González-Montelongo, MC | 1 |
| Marín, R | 1 |
| Gómez, T | 1 |
| Marrero-Alonso, J | 1 |
| Díaz, M | 1 |
| Kizub, IV | 1 |
| Pavlova, OO | 2 |
| Johnson, CD | 1 |
| Soloviev, AI | 1 |
| Zholos, AV | 1 |
| Enouri, S | 1 |
| Monteith, G | 1 |
| Johnson, R | 1 |
| Hu, LD | 1 |
| Yu, BP | 1 |
| Yang, B | 1 |
| Han, R | 1 |
| Bakker, AJ | 1 |
| Shirasawa, Y | 1 |
| Rutland, TJ | 1 |
| Young, JL | 1 |
| Dean, DA | 1 |
| Joseph, BN | 1 |
| Jeong, JH | 1 |
| Yun, MC | 1 |
| Shin, CY | 1 |
| Lee, TS | 1 |
| Song, HJ | 1 |
| Husain, S | 1 |
| Young, D | 1 |
| Wingard, CJ | 1 |
| Sahach, VF | 1 |
| Solovĭov, AI | 1 |
| Takeuchi, T | 2 |
| Kushida, M | 1 |
| Hirayama, N | 1 |
| Kitayama, M | 1 |
| Fujita, A | 1 |
| Hata, F | 2 |
| Tsai, BM | 1 |
| Wang, M | 1 |
| Pitcher, JM | 1 |
| Meldrum, KK | 1 |
| Meldrum, DR | 1 |
| Jin, JS | 1 |
| Yao, CW | 1 |
| Ka, SM | 1 |
| Chin, TY | 1 |
| Chueh, SH | 1 |
| Lee, HS | 1 |
| Sheu, LF | 1 |
| Lin, YF | 1 |
| Lee, WH | 1 |
| Chen, A | 1 |
| Teplov, AY | 1 |
| Grishin, SN | 1 |
| Zefirov, AL | 1 |
| Ziganshin, AU | 1 |
| Nakajima, H | 1 |
| Azuma, YT | 1 |
| Khattab, MM | 1 |
| Al-Rawi, MB | 1 |
| Aleisa, AM | 1 |
| Chen, Q | 2 |
| De Petris, G | 1 |
| Yu, P | 1 |
| Amaral, J | 1 |
| Biancani, P | 2 |
| Behar, J | 2 |
| Bremerich, DH | 1 |
| Warner, DO | 1 |
| Lorenz, RR | 1 |
| Shumway, R | 1 |
| Jones, KA | 1 |
| Cingolani, HE | 1 |
| Alvarez, BV | 1 |
| Ennis, IL | 1 |
| Camilión de Hurtado, MC | 1 |
| Yu, MF | 1 |
| Gorenne, I | 1 |
| Su, X | 1 |
| Moreland, RS | 1 |
| Kotlikoff, MI | 1 |
| Zhang, XH | 1 |
| Sun, JH | 1 |
| Zhu, PH | 1 |
| Trim, N | 1 |
| Holden-Dye, L | 1 |
| Walker, RJ | 1 |
| Murthy, KS | 1 |
| Grider, JR | 1 |
| Kuemmerle, JF | 1 |
| Makhlouf, GM | 1 |
| Graham, MK | 1 |
| Fairweather, I | 1 |
| McGeown, JG | 1 |
| Montgomery, DE | 1 |
| Chandra, M | 1 |
| Huang, Q | 1 |
| Jin, J | 1 |
| Solaro, RJ | 1 |
| Cao, W | 1 |
| Kim, N | 1 |
| Kirber, MT | 1 |
| Harnett, KM | 1 |
| Aboulafia, J | 1 |
| Silva, BA | 1 |
| Nouailhetas, VL | 1 |
36 other studies available for chelerythrine and Muscle Contraction
| Article | Year |
|---|---|
The flavonoid chrysin, an endocrine disrupter, relaxes cholecystokinin- and KCl-induced tension in male guinea pig gallbladder strips through multiple signaling pathways.
Topics: Animals; Benzophenanthridines; Boron Compounds; Calcium; Cholagogues and Choleretics; Cholecystokini | 2014 |
Dexmedetomidine-induced contraction involves phosphorylation of caldesmon by JNK in endothelium-denuded rat aortas.
Topics: Analysis of Variance; Animals; Anthracenes; Aorta; Benzophenanthridines; Blotting, Western; Calmodul | 2014 |
Dexmedetomidine-Induced Contraction in the Isolated Endothelium-Denuded Rat Aorta Involves PKC-δ-mediated JNK Phosphorylation.
Topics: Animals; Aorta; Azepines; Benzophenanthridines; Carbazoles; Dexmedetomidine; Endothelium, Vascular; | 2015 |
Dexmedetomidine-Induced Contraction Involves CPI-17 Phosphorylation in Isolated Rat Aortas.
Topics: Adrenergic alpha-2 Receptor Agonists; Amides; Animals; Aorta; Benzophenanthridines; Calcium; Cells, | 2016 |
Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle.
Topics: 4-Aminopyridine; Amides; Animals; Atropine; Azepines; Benzophenanthridines; Bicuculline; Calcimycin; | 2017 |
Testosterone and dihydrotestosterone inhibit gallbladder motility through multiple signalling pathways.
Topics: Animals; Benzophenanthridines; Boron Compounds; Calcium; Cholecystokinin; Dihydrotestosterone; Dose- | 2008 |
Comparison of the involvement of protein kinase C in agonist-induced contractions in mouse aorta and corpus cavernosum.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Benzophenanthrid | 2008 |
Calcium sensitization in human esophageal muscle: role for RhoA kinase in maintenance of lower esophageal sphincter tone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Benzophenanthridines; Calcium; Electric Stimu | 2008 |
Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Benzophenanthridines; Bronchodila | 2009 |
Activation of muscarinic M-1 cholinoceptors by curcumin to increase contractility in urinary bladder isolated from Wistar rats.
Topics: Animals; Benzophenanthridines; Curcumin; Estrenes; In Vitro Techniques; Male; Muscarinic Agonists; M | 2010 |
Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17.
Topics: Amides; Androgens; Animals; Benzophenanthridines; Blotting, Western; Calcium; Colon; Cycloheximide; | 2010 |
Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arteries; Benzophenanthridines; Calcium; Dia | 2010 |
Characteristics of myogenic reactivity in isolated rat mesenteric veins.
Topics: Amides; Animals; Benzophenanthridines; Calcium; Calcium Channels, L-Type; Compliance; Endothelin-1; | 2011 |
Deoxycholic acid inhibits smooth muscle contraction via protein kinase C-dependent modulation of L-type Ca2+ channels in rat proximal colon.
Topics: Acetylcholine; Animals; Benzophenanthridines; Calcium; Calcium Channels, L-Type; Cells, Cultured; Ch | 2012 |
The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat.
Topics: Alkaloids; Animals; Benzophenanthridines; Caffeine; Calcium; Electrophysiology; In Vitro Techniques; | 2003 |
Modulation of protein kinase C (PKC)-mediated contraction and the possible role of PKC epsilon in rat mesenteric arteries.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Gene Expression Regulation, Enzymologic; Gene Tra | 2003 |
Signaling via histamine receptors in cat duodenal smooth muscle cells.
Topics: Alkaloids; Animals; Benzophenanthridines; Cats; Duodenum; Enzyme Inhibitors; Ethylmaleimide; Famotid | 2003 |
Role of PKCalpha and PKCiota in phenylephrine-induced contraction of rat corpora cavernosa.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Alkaloids; Animals; Benzophenanthri | 2004 |
[Effect of inhibiting protein kinase C on calcium sensitivity of contractile apparatus of vascular smooth muscle during vasospasms of different origins].
Topics: Actin Cytoskeleton; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Hypoxia; Endothelium, Va | 2003 |
Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.
Topics: ADP Ribose Transferases; Alkaloids; Amides; Animals; Bacterial Toxins; Benzophenanthridines; Botulin | 2004 |
Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C.
Topics: Alkaloids; Animals; Benzophenanthridines; Cell Hypoxia; Cytokines; Enzyme Inhibitors; In Vitro Techn | 2004 |
IgA immune complex blunts the contraction of cultured mesangial cells through the inhibition of protein kinase C and intracellular calcium.
Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcium; Cell Size; Cells, Cultured; Enzym | 2004 |
Role of protein kinase C in the effect of ATP on contractile function of the isolated strip from mouse diaphragm.
Topics: Adenosine; Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Carbachol; Cardiotonic | 2006 |
A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon.
Topics: Alkaloids; Amides; Animals; Benzophenanthridines; Calcium; Carbachol; Carcinogens; Cholinergic Agoni | 2007 |
Postjunctional synergism of norepinephrine with ATP and diadenosine tetraphosphate in Guinea pig vas deferens. Role of protein kinase C and Myosin light chain phosphatase.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Cantharidin; Dinucleoside Phosphat | 2007 |
Different pathways mediate cholecystokinin actions in cholelithiasis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Benzimidazoles; Benzophenanthridi | 1997 |
Role of protein kinase C in calcium sensitization during muscarinic stimulation in airway smooth muscle.
Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Membrane Permeability; Cytoso | 1997 |
Stretch-induced alkalinization of feline papillary muscle: an autocrine-paracrine system.
Topics: Alkalies; Alkaloids; Amiloride; Angiotensin II; Animals; Anti-Arrhythmia Agents; Autocrine Communica | 1998 |
Sodium hydrosulfite contractions of smooth muscle are calcium and myosin phosphorylation independent.
Topics: Alkaloids; Animals; Aorta, Thoracic; Benzophenanthridines; Caffeine; Calcium; Carbonyl Cyanide p-Tri | 1998 |
Effects of phorbol esters on excitation-contraction coupling and protein kinase C activity of frog twitch muscle fibers.
Topics: Alkaloids; Animals; Anti-Bacterial Agents; Benzophenanthridines; Calcium Signaling; Cold Temperature | 1999 |
The inhibitory action of tamoxifen on the contraction of Ascaris suum somatic muscle in response to acetylcholine.
Topics: Acetylcholine; Alkaloids; Animals; Ascaris suum; Benzophenanthridines; Electrophysiology; Levamisole | 1999 |
Sustained muscle contraction induced by agonists, growth factors, and Ca(2+) mediated by distinct PKC isozymes.
Topics: Alkaloids; Animals; Antibodies; Benzophenanthridines; Bombesin; Calcium; Carbazoles; Enzyme Inhibito | 2000 |
Second messengers mediating mechanical responses to the FARP GYIRFamide in the fluke Fasciola hepatica.
Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Inhibitors; Fasciola hepatica; Guanosine Diphosphat | 2000 |
Transgenic incorporation of skeletal TnT into cardiac myofilaments blunts PKC-mediated depression of force.
Topics: Actin Cytoskeleton; Alkaloids; Animals; Benzophenanthridines; Carcinogens; Enzyme Inhibitors; Gene E | 2001 |
Ca2+-induced contraction of cat esophageal circular smooth muscle cells.
Topics: Adrenergic beta-Antagonists; Alkaloids; Animals; Antibodies; Azepines; Benzophenanthridines; Bridged | 2001 |
Protein kinase C modulators enhance angiotensin II desensitization of guinea pig ileum via maxi-K+ channels.
Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Enzyme Activation; Enzyme Inhibitors; Fema | 2002 |