chelerythrine has been researched along with Melanoma in 5 studies
chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the cytotoxic effects of a cell-permeable ceramide (Cer), N-hexanoyl-D-sphingosine (C6-Cer) and of two related sphingoid bases, sphingosine (So) and dihydrosphingosine (sphinganine; Sa) on human melanoma cell lines and on soft tissue sarcoma lines recently established from fresh surgical biopsy specimens." | 3.70 | Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. ( Auzenne, E; Feig, B; Hu, M; Klostergaard, J; Leroux, ME; Pollock, RE, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cho, O | 1 |
| Lee, JW | 1 |
| Kim, HS | 1 |
| Jeong, YJ | 1 |
| Heo, TH | 1 |
| Cavalier, MC | 1 |
| Pierce, AD | 1 |
| Wilder, PT | 1 |
| Alasady, MJ | 1 |
| Hartman, KG | 1 |
| Neau, DB | 1 |
| Foley, TL | 1 |
| Jadhav, A | 1 |
| Maloney, DJ | 1 |
| Simeonov, A | 1 |
| Toth, EA | 1 |
| Weber, DJ | 1 |
| Kemény-Beke, A | 1 |
| Aradi, J | 1 |
| Damjanovich, J | 1 |
| Beck, Z | 1 |
| Facskó, A | 1 |
| Berta, A | 1 |
| Bodnár, A | 1 |
| Park, HY | 1 |
| Russakovsky, V | 1 |
| Ao, Y | 1 |
| Fernandez, E | 1 |
| Gilchrest, BA | 1 |
| Auzenne, E | 1 |
| Leroux, ME | 1 |
| Hu, M | 1 |
| Pollock, RE | 1 |
| Feig, B | 1 |
| Klostergaard, J | 1 |
5 other studies available for chelerythrine and Melanoma
| Article | Year |
|---|---|
Chelerythrine, a novel small molecule targeting IL-2, inhibits melanoma progression by blocking the interaction between IL-2 and its receptor.
Topics: Animals; Antineoplastic Agents; Forkhead Transcription Factors; Immune Checkpoint Inhibitors; Interl | 2023 |
Covalent small molecule inhibitors of Ca(2+)-bound S100B.
Topics: Animals; Benzophenanthridines; Benzoquinones; Binding Sites; Calcium; Cations, Divalent; Cattle; Cel | 2014 |
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine.
Topics: Alkaloids; Annexin A5; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Berberine Alkaloids; | 2006 |
Alpha-melanocyte stimulating hormone-induced pigmentation is blocked by depletion of protein kinase C.
Topics: Alkaloids; alpha-MSH; Animals; Benzophenanthridines; Cell Division; Cyclic AMP; Cyclic AMP-Dependent | 1996 |
Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro.
Topics: Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzophenanthridines; Carboxyl | 1998 |