chelerythrine has been researched along with Carcinoma, Hepatocellular in 8 studies
chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chelerythrine (CHE) is a type of benzophenanthridine alkaloid found in many herbs and is also the main alkaloid constituent of Toddalia asiatica (L." | 5.48 | Chelerythrine Inhibits Human Hepatocellular Carcinoma Metastasis in Vitro. ( Chu, C; Pan, Y; Qian, Y; Wu, Y; Zhang, G; Zhong, W; Zhu, G; Zhu, Y, 2018) |
| "We have examined the effects of adenosine receptors and protein kinases A and C in the regulation of erythropoietin (Epo) production using hepatocellular carcinoma (Hep3B) cells in culture and in vivo in normal mice under normoxic and hypoxic conditions." | 3.71 | Adenosine A(2A) and A(2B) receptor activation of erythropoietin production. ( Brookins, J; Fisher, JW, 2001) |
| "Chelerythrine (CHE) is a type of benzophenanthridine alkaloid found in many herbs and is also the main alkaloid constituent of Toddalia asiatica (L." | 1.48 | Chelerythrine Inhibits Human Hepatocellular Carcinoma Metastasis in Vitro. ( Chu, C; Pan, Y; Qian, Y; Wu, Y; Zhang, G; Zhong, W; Zhu, G; Zhu, Y, 2018) |
| "Studies were performed in HTC rat hepatoma and Mz-ChA-1 human cholangiocarcinoma cells, which were used as model hepatocytes and cholangiocytes, respectively." | 1.30 | Activation of protein kinase Calpha couples cell volume to membrane Cl- permeability in HTC hepatoma and Mz-ChA-1 cholangiocarcinoma cells. ( Bodily, KO; Fitz, JG; Raymond, JR; Roman, RM; Wang, Y, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, Y | 1 |
| Pan, Y | 1 |
| Zhang, G | 1 |
| Wu, Y | 1 |
| Zhong, W | 1 |
| Chu, C | 1 |
| Qian, Y | 1 |
| Zhu, G | 1 |
| Zhang, ZF | 1 |
| Guo, Y | 1 |
| Zhang, JB | 1 |
| Wei, XH | 1 |
| Zdarilová, A | 1 |
| Vrzal, R | 1 |
| Rypka, M | 1 |
| Ulrichová, J | 2 |
| Dvorák, Z | 2 |
| Sovadinová, I | 1 |
| Bláha, L | 1 |
| Giesy, JP | 1 |
| Long, WP | 1 |
| Pray-Grant, M | 1 |
| Tsai, JC | 1 |
| Perdew, GH | 1 |
| Yoshioka, K | 1 |
| Clejan, S | 1 |
| Fisher, JW | 2 |
| Roman, RM | 1 |
| Bodily, KO | 1 |
| Wang, Y | 1 |
| Raymond, JR | 1 |
| Fitz, JG | 1 |
| Brookins, J | 1 |
8 other studies available for chelerythrine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Chelerythrine Inhibits Human Hepatocellular Carcinoma Metastasis in Vitro.
Topics: Antineoplastic Agents; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movem | 2018 |
Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Benzophenan | 2011 |
Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.
Topics: Alkaloids; Benzophenanthridines; Carcinoma, Hepatocellular; Catalysis; Cell Line, Tumor; Cytochrome | 2006 |
Quaternary benzo[c]phenathridine alkaloids sanguinarine and chelerythrine do not affect transcriptional activity of aryl hydrocarbon receptor: analyses in rat hepatoma cell line H4IIE.luc.
Topics: Alkaloids; Animals; Anti-Infective Agents; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Lin | 2006 |
Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction.
Topics: Alkaloids; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzophenanthridines; Carcinoma, Hepatoce | 1998 |
Activation of protein kinase C in human hepatocellular carcinoma (HEP3B) cells increases erythropoietin production.
Topics: Alkaloids; Benzophenanthridines; Calcimycin; Carcinoma, Hepatocellular; Diglycerides; Enzyme Activat | 1998 |
Activation of protein kinase Calpha couples cell volume to membrane Cl- permeability in HTC hepatoma and Mz-ChA-1 cholangiocarcinoma cells.
Topics: Alkaloids; Animals; Benzophenanthridines; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Catalytic | 1998 |
Adenosine A(2A) and A(2B) receptor activation of erythropoietin production.
Topics: Adenosine; Alkaloids; Benzophenanthridines; Carcinoma, Hepatocellular; Enzyme Activation; Erythropoi | 2001 |