chelerythrine has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oberstadt, M | 1 |
| Stieler, J | 1 |
| Simpong, DL | 1 |
| Römuß, U | 1 |
| Urban, N | 1 |
| Schaefer, M | 1 |
| Arendt, T | 1 |
| Holzer, M | 1 |
1 other study available for chelerythrine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
TDP-43 self-interaction is modulated by redox-active compounds Auranofin, Chelerythrine and Riluzole.
Topics: Amyotrophic Lateral Sclerosis; Animals; Auranofin; Benzophenanthridines; Cell Line, Tumor; DNA-Bindi | 2018 |