chelerythrine has been researched along with Acidosis in 4 studies
chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aimed at characterizing changes in rumen microbial abundances and fermentation profiles using a severe subacute ruminal acidosis (SARA) in vitro model, and to evaluate a potential modulatory role of plant derived alkaloids (PDA), containing quaternary benzophenanthridine and protopine alkaloids, of which sanguinarine and chelerythrine were the major bioactive compounds." | 3.83 | Rumen microbial abundance and fermentation profile during severe subacute ruminal acidosis and its modulation by plant derived alkaloids in vitro. ( Chizzola, R; Khiaosa-Ard, R; Klevenhusen, F; Metzler-Zebeli, BU; Mickdam, E; Zebeli, Q, 2016) |
| " The alkalosis was completely blocked by the NHE inhibitor, cariporide, and by sodium-free bathing solutions, indicating it was mediated by NHE activation." | 3.77 | Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes. ( Ajiro, Y; Giles, WR; Saegusa, N; Spitzer, KW; Stafforini, DM, 2011) |
| "Troglitazone was studied in pH-sensitive LLC-PK1-F+ cells to determine the effect on pHi and glutamine metabolism as well as the role of peroxisome proliferator-activated receptor (PPARgamma)-dependent and PPARgamma-independent signaling pathways." | 1.32 | Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism. ( Fowler, R; Friday, E; Nissim, I; Turturro, F; Welbourne, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mickdam, E | 1 |
| Khiaosa-Ard, R | 1 |
| Metzler-Zebeli, BU | 1 |
| Klevenhusen, F | 1 |
| Chizzola, R | 1 |
| Zebeli, Q | 1 |
| Ajiro, Y | 1 |
| Saegusa, N | 1 |
| Giles, WR | 1 |
| Stafforini, DM | 1 |
| Spitzer, KW | 1 |
| Welbourne, T | 1 |
| Friday, E | 1 |
| Fowler, R | 1 |
| Turturro, F | 1 |
| Nissim, I | 1 |
| Cohen, MV | 1 |
| Yang, XM | 1 |
| Downey, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for chelerythrine and Acidosis
| Article | Year |
|---|---|
Rumen microbial abundance and fermentation profile during severe subacute ruminal acidosis and its modulation by plant derived alkaloids in vitro.
Topics: Acidosis; Alkaloids; Animal Feed; Animals; Benzophenanthridines; Berberine Alkaloids; Cattle; Diet; | 2016 |
Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes.
Topics: Acidosis; Alkalosis; Animals; Azepines; Benzophenanthridines; Dose-Response Relationship, Drug; Flav | 2011 |
Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism.
Topics: Acid-Base Equilibrium; Acidosis; Alanine; Alkaloids; Animals; Antineoplastic Agents; Benzhydryl Comp | 2004 |
The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis.
Topics: Acidosis; Alkaloids; Animals; Apoptosis; Benzophenanthridines; Buffers; Carbon Dioxide; Catheterizat | 2007 |